Morgan Penny, B.S.
Adrenocortical carcinoma (ACC)
Adrenocortical carcinoma (ACC) is a rare and aggressive cancer that affects 1-2 people per million in the United States annually. Oncogenic Β-catenin mutations occur in ~20% of all ACCs and are associated with poor prognosis. I am working to define the signature of proteins that are expressed in ACCs characterized by oncogenic β-catenin mutations, and their role in cancer proliferation, invasion, and metastasis.