Bartke, A., L Y. Sun, X. Li, R. A. Miller. 2022. Early life interventions can shape aging. Front. Endocrinol. 13:797581. doi: 10.3389/fendo.2022.797581.

Garratt, M., I. Erturk, R. Alonzo, F. Zufall, T. Leinders-Zufall., S. Pletcher, R. A. Miller. 2022. Lifespan extension in female mice by early, transient exposure to adult female olfactory cues. eLife 2022;11:e84060. DOI: https://doi.org/10.7554/eLife.84060 [bioRxiv 2022.10.07.511218; doi: https://doi.org/10.1101/2022.10.07.511218. PMID: 36525360.

Li, X, M. Hager, M. McPherson, M. Lee, R. Hagalwadi, M. Skinner, D. Lombard, R. A. Miller. 2022. Recapitulation of anti-aging phenotypes by global, but not by muscle-specific, deletion of PAPP-A in mice. Geroscience doi: 10.1007/s11357-022-00692-3. PMID: 36542300. PMC9886707.

Li, X., M. McPherson, M. Hager, Y. Fang, A. Bartke, R. A. Miller. 2022. Transient early life growth hormone exposure alters brain, muscle, liver, macrophages, and adipocytes in long-lived Ames dwarf mice. FASEB J., doi: 10.1096/fj.202200143R. PMID: 35704312.

Li, X., X. Shi, M. McPherson, M. Hager, G. G. Garcia, R. A. Miller. 2022. Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant mice. Aging Cell doi.org/10.1111/acel.13685. PMID: 35930768

Miller HA, Huang S, Dean ES, Schaller ML, Tuckowski AM, Munneke AS, et al. Serotonin and dopamine modulate aging in response to food odor and availability. Nat Commun. 2022;13(1):3271. Epub 20220607. doi: 10.1038/s41467-022-30869-5. PubMed PMID: 35672307; PubMed Central PMCID: PMCPMC9174215.

Munneke AS, Chakraborty TS, Porter SS, Gendron CM, Pletcher SD. 2022. The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster. Front Aging. Dec 1;3:1068455. doi: 10.3389/fragi.2022.1068455. PMID: 36531741; PMCID: PMC9751412.

Wink, L., R. A. Miller, G. G. Garcia. 2022. Rapamycin, acarbose, and 17 -estradiol share common mechanisms regulating the MAPK signaling pathways involved in hormonal signaling and inflammation. Immunity and Ageing. DOI: 10.1186/s12979-022-00264-1. PMID: 35105357. PMCID: PMC8805398

Beydoun S, Choi HS, Dela-Cruz G, Kruempel J, Huang S, Bazopoulou D, Miller HA, Schaller ML, Evans CR, Leiser SF. An alternative food source for metabolism and longevity studies in Caenorhabditis elegans. Commun Biol. 2021 Feb 26;4(1):258. doi: 10.1038/s42003-021-01764-4. PMID: 33637830; PMCID: PMC7910432.

Lu, Y.-X., J. C. Regan, J. Eber, L. F. Drews, T. Weinseis, J. Stinn, O. Hahn, R. A. Miller, S. Grönke, L Partridge. 2021. A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to promote healthy longevity. eLife 10:e62233. PMID: 33988501. PMC8186904. DOI: 10.7554/eLife.62233

Luo Y, Johnson J, Chakraborty T, Piontkowski A, Pletcher SD. 2021. Indirect exposure to yeast volatiles doubles Drosophila starvation survival. Science Advances, May 12;7(20):eabf8896. doi: 10.1126/sciadv.abf8896s.

Lyu Y, Holme KJ, Promislow DEL , Pletcher SD. 2021. Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice in Drosophila melanogaster. Communications Biology. Jun 15;4(1):740. doi: 10.1038/s42003-021-02260-5.

Lyu Y, Holme KJ, Shaukat H, Plumhoff MI, Tjilos M, Promislow DEL , Pletcher SD. 2021 Serotonin 2A receptor coordinates central metabolic processes to modulate aging and physiology in response to nutrient choice. ELife. DOI: 10.7554/eLife.59399

Miller HA, Dean ES, Pletcher SD, Leiser SF.2020. Cell non-autonomous regulation of health and longevity. Elife. 2020 Dec 10;9:e62659. d10.7554/eLife.62659.PMID: 33300870

Shen, Z., A. Hinson, R. A. Miller, G. G. Garcia. 2021. Cap-independent translation: a shared mechanism for lifespan extension by rapamycin, acarbose, and 17a-estradiol. Aging Cell 20(5):e13345. DOI: 10.1111/acel.13345. PMID: 33742521. PMC8135077 DOI: 10.1111/acel.13345

Cho CS, Xi J, Si Y, Park SR, Hsu JE, Kim M, Jun G, Kang HM, Lee JH. Microscopic examination of spatial transcriptome using Seq-Scope. Cell. 2021 Jun 24;184(13):3559-3572.e22. doi: 10.1016/j.cell.2021.05.010. Epub 2021 Jun 10. PubMed PMID: 34115981; PubMed Central PMCID: PMC8238917.

Debarba, L. K., H. Jayarathne, R. A. Miller, M. Garratt, M. Sadagurski. 2021. 17-a-estradiol has sex-specific effects on neuroinflammation that are partly reversed by gonadectomy. J. Gerontol. Biol. Sci., in press. PMID: 34309657.

Endicott, S. J., A. C. Monovich, E. L. Huang, E. I. Henry, D. N. Boynton, Jr., L. J. Beckmann, M. J. MacCoss, R. A. Miller. 2021. Lysosomal targetomics in ghr KO mice reveals a role for enhanced chaperone-mediated autophagy in shaping specific molecular pathways. Autophagy, in press. https://doi.org/10.1080/15548627.2021.1990670.

Ewart, D., L. Harper, A. Gravely, R. A. Miller, C. S. Carlson, R.F. Loeser. 2020. Naturally occurring osteoarthritis in male mice exposed to drugs that extend lifespan. Connective Tissue Research 61:95 - 103. doi:10.1080/03008207.2019.1635590. PMID: 31530037. PMC6884676.

Gendron CM, Chakraborty TS, Chung BY, Harvanek ZM, Holme KJ, Johnson JC, Lyu Y, Munneke AS, and Pletcher SD. 2020. Neuronal mechanisms that drive organismal aging through the lens of perception. Annual Review of Physiology. 82:227-249.

Gendron CM, Chakraborty TS, Duran C, Dono T, Pletcher SD. Ring neurons in the Drosophila central complex act as a rheostat for sensory modulation of aging. PLoS Biol. 2023 Jun 13;21(6):e3002149. doi: 10.1371/journal.pbio.3002149. PMID: 37310911; PMCID: PMC10263353.

Giblin W, Bringman-Rodenbarger L, Guo AH, Kumar S, Monovich AC, Mostafa AM, Skinner ME, Azar M, Mady AS, Chung CH, Kadambi N, Melong KA, Lee HJ, Zhang L, Sajjakulnukit P, Trefely S, Varner EL, Iyer S, Wang M, Wilmott JS, Soyer HP, Sturm RA, Pritchard AL, Andea AA, Scolyer RA, Stark MS, Scott DA, Fullen DR, Bosenberg MW, Chandrasekaran S, Nikolovska-Coleska Z, Verhaegen ME, Snyder NW, Rivera MN, Osterman AL, Lyssiotis CA, Lombard DB. The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics. J Clin Invest. 2021 Jun 15;131(12):e138926. doi: 10.1172/JCI138926. PMID: 33945506; PMCID: PMC8203465.

Korfhage J, Skinner ME, Basu J, Greenson JK, Miller RA, Lombard DB. Canagliflozin increases intestinal adenoma burden in female Apc Min/+ mice. J Gerontol A Biol Sci Med Sci. 2021 Aug 27:glab254. doi: 10.1093/gerona/glab254. Epub ahead of print. PMID: 34448851.

Kumar, S., Giblin, W., and Lombard D.B. (2020). Sirtuins, Healthspan, and Longevity in Mammals. In Handbook of the Biology of Aging, Elsevier, 9th edition.

Kumar S, Jones M, Li Q, Lombard DB. Assessment of Cellular Bioenergetics in Mouse Hematopoietic Stem and Primitive Progenitor Cells using the Extracellular Flux Analyzer. J Vis Exp. 2021 Sep 24;(175). doi: 10.3791/63045. PMID: 34633378.

Kumar S, Lombard DB. SIRT5's GOT1 up on PDAC. Gastroenterology. 2021 Jul 16:S0016-5085(21)03254-6. doi: 10.1053/j.gastro.2021.07.020. Epub ahead of print. PMID: 34280390.

Li, X., J. A. Frazier, E. Spahiu, M. McPherson, and R. A. Miller. 2020, Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice. Aging 12: 8677 - 8789. PMID: 32464603 PMC7288969.

Lombard DB, Kohler W, Guo AH, Gendron C, Han M, Ding W, Lyu Y, Ching T, Wang F, Chakraborty T, Nikolovska-Coleska Z, Duan Y, Girke T, Hsu A, Pletcher SD, Miller R. 2020. High throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Science Advances. 6 (40).

Lyu Y, Holme KJ, Promislow DEL , Pletcher SD. 2020. Complex nutritional environment modulates aging-associated metabolic network integrity through serotonin signaling in Drosophila. 2020. ELife. In Review.

Lyu Y, Holme KJ, Shaukat H, Plumhoff MI, Tjilos M, Promislow DEL , Pletcher SD. 2020 Serotonin 2A receptor coordinates central metabolic processes to modulate aging and physiology in response to nutrient choice. ELife. In Revision.

Beydoun S, Choi HS, Dela-Cruz G, Kruempel J, Huang S, Bazopoulou D, Miller HA, Schaller ML, Evans CR, Leiser SF. An alternative food source for metabolism and longevity studies in Caenorhabditis elegans. Commun Biol. 2021 Feb 26;4(1):258. doi: 10.1038/s42003-021-01764-4. PMID: 33637830; PMCID: PMC7910432. Chakraborty TS, Gendron CM, Lyu Y, Munneke AS, DeMarco MN, Hoisington ZW, Pletcher SD: Sensory perception of dead conspecifics induces aversive cues and modulates lifespan through serotonin in Drosophila. Nat Commun 2019, 10(1):2365.

Endicott, S. J., D. N. Boynton, Jr., L. J. Beckmann, and R. A. Miller. 2020. Long-lived mice with reduced growth hormone signaling have a constitutive upregulation of hepatic chaperone-mediated autophagy. Autophagy, in press. doi: 10.1080/15548627.2020.1725378 PMID: 32013718

Endicott, S. J., Z. J. Ziemba, L. J. Beckmann, D. N. Boynton, and R. A. Miller. 2020. Chaperone-mediated autophagy is controlled by the INS-PI3K-PDPK1 signaling pathway. J. Cell Biol. 219 (12): e202001031. https://doi.org/10.1083/jcb.202001031. PMID: 33048163.

Ewart, D., L. Harper, A. Gravely, R. A. Miller, C. S. Carlson, R.F. Loeser. 2020. Naturally occurring osteoarthritis in male mice exposed to drugs that extend lifespan. Connective Tissue Research 61:95 - 103. doi:10.1080/03008207.2019.1635590. PMID: 31530037. PMC6884676.

Garratt, M., D. Leander, K. Pifer, B. Bower, J. J. Herrera, S. M. Day, O. Fiehn,. S. V. Brooks, R. A. Miller. 2019. 17-? estradiol ameliorates age-associated sarcopenia and improves late life physical function in male mice but not in females or castrated males. Aging Cell, DOI: 10.1111/acel.12920. PMID: 30740872. PMC6413653.

Gendron CM, Chakraborty TS, Chung BY, Harvanek ZM, Holme KJ, Johnson JC, Lyu Y, Munneke AS, Pletcher SD: Neuronal Mechanisms that Drive Organismal Aging Through the Lens of Perception. Annu Rev Physiol 2020, 82:227-249.

Harrison DE, Strong R, Alavez S, Astle CM, DiGiovanni J, Fernandez E, Flurkey K, Garratt M, Gelfond JAL, Javors MA, Levi M, Lithgow GJ, Macchiarini F, Nelson JF, Sukoff Rizzo SJ, Slaga TJ, Stearns T, Wilkinson JE, Miller RA. Acarbose improves health and lifespan in aging HET3 mice. Aging Cell. 2019 Apr;18(2):e12898. doi: 10.1111/acel.12898. Epub 2019 Jan 27. PMID: 30688027; PMCID: PMC6413665.

Harrison BR, Wang L, Gajda E, Hoffman EV, Chung BY, Pletcher SD, Raftery D, Promislow DEL: The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster. BMC Genomics 2020, 21(1):341.

Herbst, A., A. N. Hoang, W. Woo, D. McKenzie, J. M. Aiken, R. A. Miller, D. B. Allison, N. Liu, J. Wanagat. 2019. Mitochondrial DNA alterations in aged macrophage migration inhibitory factor-knockout mice. Mech. Ageing Dev. 182: 111 - 126. doi: 10.1016/j.mad.2019.111126. PMID: 31381889. PMC6718337.

Herrera, J. J., S. Louzon, K. Pifer, D. Leander, G. Merrihew, K. Szczesniak, J. Whitson, J. E. Wilkinson, O. Fiehn, M. MacCoss, S. M. Day, R. A. Miller, and M. Garratt. 2020. Acarbose has sex-dependent and independent effects on age-related physical function, cardiac health and lipid biology. JCI Insight Sep 29;137474. doi: 10.1172/jci.insight.137474. PMID: 32990683.

Kruempel JCP, Howington MB, and Leiser SF: "Computational Tools for Geroscience", Translational Medicine of Aging, 3:132-143, 2019. doi: 10.1016/j.tma.2019.11.004

Kruempel JCP, Miller HA, Schaller M, Huang S, Sarker M, Fretz A, and Leiser SF, "Hypoxic response regulators RHY-1 and EGL-9/PHD promote longevity through a VHL-1 independent transcriptional response." Geroscience. (In Press), 2020. PMID 32399915

Lombard DB, Kohler WJ, Guo AH, Gendron C, Han M, Ding W, Lyu Y, Ching TT, Wang FY, Chakraborty TS et al: High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 2020, 6(40).

Lombard, D. B., W. Kohler, A. H. Guo, C. Gendron, M. Han, W. Ding, Y. Lyu, T.T. Ching, F. Y. Want, T. Chakraborty, X. Li, X. Shi, Z. Nikolovska-Coleska, Y. Duan, T. Girke, A.-L. Hsu, S. D. Pletcher, and R. A. Miller. 2020. High throughput small molecule screening reveals NRF2-dependent and independent pathways of cellular stress resistance. Science Advances 6 : eaaz7628. https://www.biorxiv.org/content/10.1101/778548v1

Lombard, D.B., Kohler, W.J., Guo, A.H., Gendron, C., Han, M., Ding, W., Lyu, Y., Ching, T.-T., Wang, F.-Y., Chakraborty, T.S., Nikolovsoka-Coleska, N., Duan, Y., Girke, T., Hsu, A.-L., Pletcher, S.D., and Miller, R.A. (2020). High throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci. Advances 6(40):eaaz7628. doi: 10.1126/sciadv.aaz7628.

Mau, T., M. O'Brien, A. K. Ghosh, R. A. Miller, and R. Yung. 2019. Lifespan extension drug interventions affect adipose tissue inflammation in aging. J. Gerontol. Biol. Sci., in press; doi: 10.1093/gerona/glz177. PMID: 31353414.

May CE, Vaziri A, Lin YQ, Grushko O, Khabiri M, Wang QP, Holme KJ, Pletcher SD, Freddolino PL, Neely GG et al: High Dietary Sugar Reshapes Sweet Taste to Promote Feeding Behavior in Drosophila melanogaster. Cell Rep 2019, 27(6):1675-1685 e1677.

Miller HA, Dean ES, Pletcher SD, Leiser SF. Cell non-autonomous regulation of health and longevity. Elife. 2020 Dec 10;9:e62659. doi: 10.7554/eLife.62659. PMID: 33300870; PMCID: PMC7728442.

Munkacsy E, Chocron ES, Quintanilla L, Gendron CM, Pletcher SD, Pickering AM: Neuronal-specific proteasome augmentation via Prosbeta5 overexpression extends lifespan and reduces age-related cognitive decline. Aging Cell 2019, 18(5):e13005.

Ozkurede, U., and R. A. Miller. 2019. Improved mitochondrial stress response in long-lived Snell dwarf mice. Aging Cell. e13030. https ://doi.org/10.1111/acel.13030. PMID: 31423721. PMC6826134.

Ozkurede, U., R. Kala, C. Johnson, Z. Shen, R. A. Miller, and G. G. Garcia. 2019. Cap-independent mRNA translation is upregulated in long-lived endocrine mutant mice. J. Molec. Endo. 63:123-138. https://doi.org/10.1530/JME-19-0021. PMID: 31357177. PMC6691957.

Reid, J. J., M. A. Linden, F. F. Peelor III, R. A. Miller, K. L. Hamilton, and B. F. Miller. Brain protein synthesis rates in the UM-HET3 mouse following treatment with rapamycin or rapamycin with metformin. 2019. J. Gerontol. Biol. Sci doi: 10.1093/gerona/glz069. PMID: 30864661.

Schmitt RE, Messick MR, Shell BC, Dunbar EK, Fang HF, Shelton KL, Venton BJ, Pletcher SD, Grotewiel M: Dietary yeast influences ethanol sedation in Drosophila via serotonergic neuron function. Addict Biol 2020, 25(4):e12779.

Smith, B. J., R. A. Miller, A. C. Ericsson, D. E. Harrison, R. Strong, T. M. Schmidt. 2019. Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice. bioRxiv 311456; DOI: 10.1186/s12866-019-1494-7 BMC Microbiology 19:130. PMID: 31195972.

Tyshkovskiy, A., A. A. Borodinova, G. P. Ables, M. Garratt, P. Khaitovich, R. A. Miller, V. N. Gladyshev. 2019. Identification and application of gene expression signatures of lifespan-extending interventions. Cell Metabolism, DOI:10.1016/j.cmet.2019.06.018. PMID: 31353263. PMC6907080.

Altschuler RA, Kanicki A, Martin C, Kohrman DC, Miller RA. Rapamycin but not acarbose decreases age-related loss of outer hair cells in the mouse Cochlea. Hear Res. 2018 Dec;370:11-15. doi: 10.1016/j.heares.2018.09.003. Epub 2018 Sep 7. PMID: 30245283; PMCID: PMC6240471.

Bielas, J., A. Herbst, K. Widjaja, J. Hui, J. M. Aiken, D. McKenzie, R. A. Miller, S. Brooks, and J. Wanagat. 2018. Long term rapamycin treatment improves mitochondrial DNA quality control in aging mice. Experimental Gerontology 106:125-131. doi.org/10.1016/j.exger.2018.02.021. PMID: 29486228.

Bringman-Rodenbarger, L. R., A. H. Guo, C. A. Lyssiotis, and D. B. Lombard. 2018. Emerging roles for sirt5 in metabolism and cancer. Antioxid Redox Signal 28:677-690. PMC5824490; PMID: 28707979.

Chakraborty T. M., C. M. Gendron, Y. Lyu, A. S. Munneke, M. N. DeMarco, Z. W. Hoisington, and S. D. Pletcher. 2018. Serotonin links psychological experience and aging in Drosophila. Submitted.

Garratt, M., K. Lehmann, Y.-M. Tsai, A. Galecki, M. Jain, and R. A. Miller. 2018. Male lifespan extension with 17-? estradiol is linked to a sex-specific metabolomic response modulated by gonadal hormones in mice. Aging Cell. http://dx.doi.org/10.1111/acel.12786.

Gendron, C. and S. D. Pletcher. 2018. MicroRNAs mir-184 and let-7 alter Drosophila metabolism and longevity. Aging Cell. 6:1434-1438. PMID: 28963741.

Kumar, S. and D. B. Lombard. 2018. Functions of the sirtuin deacylase SIRT5 in normal physiology and pathobiology. Crit Rev Biochem Mol Biol 53:311-334. PMID: 29637793.

Stein, A. B., W. Giblin, A. H. Guo, and D. B. Lombard. 2018. Roles for sirtuins in cardiovascular biology. In Introductory Review on Sirtuins in Biology, Aging, and Disease. L. Guarente, R. Mostoslavsky, and A. Kazantsev, eds. Academic Press, London, UK. 155-174.

Arbuthnott D, Fedina TY, Pletcher SD, Promislow DE. 2017. Mate choice in fruit flies is rational and adaptive. Nat Commun. Jan 17;8:13953. doi: 10.1038/ncomms13953. PMID: 28094789. PMC5247575.

Bajwa, P., S. Nielsen, J. M. Lombard, L. Rassam, P. Nahar, B. Rueda, J. Erby Wilkinson, R. A. Miller, P. S. Tanwar. 2017. Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice. Oncotarget, Jan 31;8(5):7265-7275. doi: 10.18632/oncotarget.13919. PMID: 27980219. PMCID: PMC5352319.

Bringman-Rodenbarger LR, Guo AH, Lyssiotis CA, Lombard DB. Emerging Roles for SIRT5 in Metabolism and Cancer. Antioxid Redox Signal. 2018 Mar 10;28(8):677-690. doi: 10.1089/ars.2017.7264. Epub 2017 Oct 26. PMID: 28707979; PMCID: PMC5824490

Cady G, Landeryou T, Garratt M, Kopchick JJ, Qi N, Garcia-Galiano D, Elias CF, Myers MG Jr, Miller RA, Sandoval DA, Sadagurski M. Hypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neurons. Mol Metab. 2017 Mar 16;6(5):393-405. doi: 10.1016/j.molmet.2017.03.001. PMID: 28462074; PMCID: PMC5404104.

Cho C. S., Lombard, D. B., and J. H. Lee. 2017. SIRT3 as a Regulator of Hepatic Autophagy. Hepatology, Epub ahead of print. doi: 10.1002/hep.29271. PMID: 28520180.

Chung, B. C., J. R. Ro, K. M. Miller, S. Kondo, and S. D. Pletcher. 2017. The Drosophila neuropeptide F circuit integrates feeding and sleep-wake behavior. Cell Reports 19:2441-2450. doi: 10.1016/j.celrep.2017.05.085. PMID: 28636933.

Cole, J J., N. A. Robertson, M. I. Rather, T. McBryan, C. Brock, W. Clark, R. A. Miller, H. Brown-Borg, P. D. Adams. 2017. Diverse interventions that extend mouse lifespan suppress shared age associated epigenetic changes at critical gene regulatory regions. Genome Biology 28:58. doi: 10.1186/s13059-017-1185-3. PMID: 28351383. PMC5370462.

Dominick, G., J. Bowman, X. Li, R. A. Miller and G. Garcia. 2017. mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GRKO, and PAPPA-KO mice. Aging Cell 16:52-60. doi: 10.1111/acel.12525. PMID: 27618784.

Fang, Y., S. McFadden. J. Darcy, C. M Hill, J. A. Huber, S. Verhulst, J. J. Kopchick, R. A Miller, L. Y. Sun, A. Bartke. 2017. Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice. Geroscience 39:347-356. PMID: 28523599. PMC5505892.

Fedina, T. and S. D. Pletcher. 2017. Tissue-specific insulin signaling effects on female attractiveness and reproductive function. PLoS Genetics 13(8):e1006935. doi: 10.1371/journal.pgen.1006935. PMID: 28817572

Garratt, M., B. Bower, G. G. Garcia, and R. A. Miller. 2017. Sex-differences in lifespan-extension with acarbose and 17-? estradiol: gonadal hormones underlie male-specific improvements in glucose tolerance and mTORC2 signaling. Aging Cell 16:1256-1266. doi: 10.1111/acel.12656. PMID: 28834262.

Gendron, C. and S. D. Pletcher. 2017. MicroRNAs mir-184 and let-7 Alter Drosophila Metabolism and Longevity. Aging Cell (in press).

Giblin, W. and D. B. Lombard. 2017. Sirtuin 6 builds a wall against inflammation, trumping diabetes. Diabetes 66:2535-2537. PMC5606319; PMID: 28931553.

Harvanek, Z., Y. Lyu, J. Johnson, S. Kondo, D. Promislow, S. D. Pletcher. Perceptive costs of reproduction drive ageing and physiology in male Drosophila. 2017. Nature Ecology and Evolution, doi:10.1038/s41559-017-0152.

Hine, C., H-J. Kim, Y. Zhu, E. Harputlugil, A. Longchamp, M. S. Matos, P. Ramadoss, K. Bauerle, L. Brace, J. M. Asara, C. K. Ozaki, S.-y. Cheng, S. Singha, K. H. Ahn, A. Kimmelman, F. M. Fisher, P. Pissios, D. J. Withers, C. Selman, R. Wang, K. Yen, V. Longo, P. Cohen, A. Bartke, J. J. Kopchick, R. Miller, A. N. Hollenberg, J. R. Mitchell. 2017. Hypothalamic-pituitary axis regulates hydrogen sulfide production. Cell Metabolism, Jun 6;25(6):1320-1333.e5. http://dx.doi.org/10.1016/j.cmet.2017.05.003 PMID: 28591635.

Hoffman, J. M., Y. Lyu, S. D. Pletcher, and D. E. L. Promislow. 2017. Proteomics and metabolomics in ageing research: from biomarkers to systems biology. Essays Biochem 61:379-388. PMID: 28698311.

Kumar, S., and D. B. Lombard. 2017. Cycling around Lysine Modifications. Trends in Biochemical Sciences, Epub ahead of print. doi: 10.1016/j.tibs.2017.05.006. PMID: 28595832.

Kumar, S., and D. B. Lombard. 2017. For Certain, SIRT4 activities! Trends in Biochemical Sciences, Epub ahead of print. doi: 10.1016/j.tibs.2017.05.008. PMID: 28587732.

Lee, J-E, M. Rayyan, I. Edery, and S. D. Pletcher. 2017. Acute protein restriction acts via TOR, PP2A, and Myc signaling to boost innate immunity in Drosophila. Cell Reports, 20:479-490. doi: 10.1016/j.celrep.2017.06.052. PMID: 28700947.

Lombard, D. B., R. A. Miller, and S. D. Pletcher. 2017. Biology of Aging and Longevity. Hazzard's Geriatric Medicine and Gerontology, 7th Edition. Eds: J. B. Halter, J. G. Ouslander, S. Studenski, K. P. High, S. Asthana, M. A. Supiano, C. Ritchie. Chapter 1, pages 3 - 24. McGraw-Hill, New York.

Lombard, D. B. and Y. Zhao. 2017. ACSF3 and mal(onate)-adapted mitochondria. Cell Chem Biol 24:649-650. PMID: 28644952.

Miller H., M. Fletcher, M. Primitivo, A. Leonard, G. L. Sutphin, N. Rintala, M. Kaeberlein, and S. F. Leiser. 2017. Genetic interaction with temperature is an important determinant of nematode longevity. Aging Cell 16:1425-1429. PMID: 28940623.

Petkovich, D. A., D. I. Podolskiy, A. V. Lobanov, S.-G. Lee, R. A. Miller and V. N. Gladyshev. 2017. Using DNA methylation profiling to evaluate biological age and longevity interventions. Cell Metabolism, dx.doi.org/10.1016/j.cmet.2017.03.016. PMID: 28380383.

Pickering, A. M., M. Lehr, C. M Gendron, S. D Pletcher, R. A Miller. 2017. Mitochondrial Thioredoxin Reductase 2 is elevated in long?lived primate and rodent species and in long?lived mutant mice, and extends fly lifespan. Aging Cell, May 5. doi: 10.1111/acel.12596. PMID: 28474396.

Rossner R, Kaeberlein M, Leiser SF. Flavin-containing monooxygenases in aging and disease: Emerging roles for ancient enzymes. J Biol Chem. 2017 Jul 7;292(27):11138-11146. doi: 10.1074/jbc.R117.779678. Epub 2017 May 17. PMID: 28515321; PMCID: PMC5500783

Sadagurski, M., G. Cady, and R. A. Miller. 2017. Anti-aging drugs reduce hypothalamic inflammation in a sex-specific manner. Aging Cell 16:652-660. PMID: 28544365.

Bajwa, P., P. B. Nagendra, S. Nielsen, A. Bielanowicz, J. M. Lombard, J. E. Wilkinson, M. Serrano, R. A. Miller, P. S. Tanwar. 2016. Age related increase in mTOR activity contributes to the pathological changes in ovarian surface epithelium. 2016. Oncotarget 7:14-27. doi: 10.18632/oncotarget.8468. PMID: 27036037. PMC4991377.

Guetschow, E D., S. Kumar, D. B. Lombard, and R. T. Kennedy. 2016. Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples. Analytical and Bioanalytical Chemistry 408:721-31. doi: 10.1007/s00216-015-9206-0. PMID: 26635020. PMC4712073.

Harvanek, Z. M., Mourao, M.A., Schnell, S., Pletcher, S.D., 2016. A computational approach to studying aging at the individual level. Proc Biol Sci 283: 1824. PMID: 26865300. PMC4760160.

Kumar, S., and D. B. Lombard. 2016. Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules. F1000 Res. 2016 Mar 29;5. pii: F1000 Faculty Rev-406. doi: 10.12688/f1000research.7821.1. PMID: 27081480. PMC4813637.

Kumar, S., and D. B. Lombard. 2016. Generation and purification of catalytically active SIRT5. Methods in Molecular Biology 1436:241-57. doi: 10.1007/978-1-4939-3667-0 16. PMID: 27246219. PMC4890613.

Ma, S., A. Upneja, A. Galecki, Y.-M. Tsai, C. Burant, S. Raskind, Q. Zhang, Z. D. Zhang, A. Seluanov, V. Gorbunova, C. B. Clish, R. A. Miller, and V. N. Gladyshev. 2016. Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity. eLife 2016;10.7554/eLife.19130. PMID: 27874830.

Miller, R. A. 2016. Not your father's (or mother's) rodent: moving beyond B6. Neuron dx.doi.org/10.1016/j.neuron.2016.09.009. PMID: 27657444.

Novgorodov S. A., Riley C. L., Keffler J. A., Yu J., Kindy M. S., Macklin W. B., Lombard D. B., and T. I. Gudz. 2016. SIRT3 Deacetylates Ceramide Synthases: Implications for Mitochondrial Dysfunction and Brain Injury. The Journal of biological chemistry 291(4):1957-73. DOI: 10.1074/jbc.M115.668228. PMID: 26620563. PMC4722471.

Ro J., G. Pak, P. A. Malec, Y. Lyu, D. B. Allison, R. T. Kennedy, and S. D. Pletcher. 2016. Serotonin signaling mediates protein valuation and aging. ELife. Aug 23;5. pii: e16843. doi: 10.7554/eLife.16843. PMID: 27572262.

Richardson A., K. E. Fischer, J. R. Speakman, R. de Cabo, S. J. Mitchell, C. A. Peterson, P. Rabinovitch, Y., A. Chiao, G. Taffet, R. A. Miller, R. C. Rentería, J. Bower, D. K. Ingram, W. C. Ladiges, Y. Ikeno, F. Sierra, S. N. Austad. 2016. Measures of healthspan as indices of aging in mice - A recommendation. J Gerontol A Biol Sci Med Sci. 71:427-430. PMID: 26287941. PMC4834833.

Strong, R., R. A. Miller, A. Antebi, C. M. Astle, M. Bogue, M. S. Denzel, E. Fernandez, K. Flurkey, K. L. Hamilton, D. W. Lamming, M. A. Javors, J. P. de Magalhães, J. M. McCord, B. F. Miller, M. Müller, J. F. Nelson, J. Ndukum, G. E.. Rainger, A. Richardson, D. M. Sabatini, A. B. Salmon, J. W. Simpkins, W. T. Steegenga, N. L. Nadon, D. E. Harrison. 2016. Longer lifespan in male mice treated with a non-feminizing steroid, an antioxidant, an ?-glucosidase inhibitor or a Nrf2-inducer. Aging Cell 15: 872 - 884. doi: 10.1111/acel.12496. PMID: 27312235. PMC5013015.

Tan, M., C. Peng, K. A. Anderson, P. Chhoy, Z. Xie, L. Dai, J. Park, Y. Chen, Z. Xie, D. Zhang, D. Chung, Z. Tang, H. Huang, L. Dai, S. Qi, J. Li, G. Colak, Y. Chen, C. Xia, C. Peng, H. Ruan, M. Kirkey, D. Wang, L. M. Jensen, O. K. Kwon, S. Lee, S. D. Pletcher, M. Tan, D. B. Lombard, K. P. White, H. Zhao, J. Li, R. G. Roeder, X. Yang, Y. Zhao. 2016. Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation. Mol Cell 62:194-206. PMC5540445; PMID: 27105115.

B., White, K. P., Zhao, H., Li, J., Roeder, R. G., Yang, X., and Y. Zhao. 2016. Metabolic Regulation of Gene Expression by Histone Lysine ?-Hydroxybutyrylation. Molecular Cell 62(2):194-206. doi: 10.1016/j.molcel.2016.03.036. PMID: 27105115.

Zaseck, L. W., R. A. Miller, and S. V. Brooks. 2016. Rapamycin attenuates age-associated changes in tibialis anterior tendon viscoelastic properties. J. Gerontol. Biol. Sci. doi: 10.1093/gerona/glv307. PMID: 26809496. PMC4906327.

Colak, G., O. Pougovkina, L. Dai, M. Tan, H. Te Brinke, H. Huang, Z. Cheng, J. Park, X. Wan, X. Liu, W. W. Yue, R. J. Wanders, J. W. Locasale, D. B. Lombard, V. C. de Boer, and Y. Zhao. 2015. Proteomic and biochemical studies of lysine malonylation suggest its malonic aciduria-associated regulatory role in mitochondrial function and fatty acid oxidation. Mol Cell Proteomics 14:3056-3071. PMC4638046; PMID: 26320211.

Kumar, S. and D. B. Lombard. 2015. Mitochondrial sirtuins and their relationships with metabolic disease and cancer. Antioxid Redox Signal 22:1060-1077. PMC4389911; PMID: 25545135.

Linford, N. J., J. Ro, B. Y. Chung, and S. D. Pletcher. 2015. Gustatory and metabolic perception of nutrient stress in Drosophila. Proc Natl Acad Sci U S A 112:2587-2592. PMID: 25675472.

D. B. Lombard. 2015. Aging. Rubin’s Pathology, 7th Edition. Eds. D. S. Strayer and E. Rubin. Chapter 10, pages 477-485. Wolters Kluwer, Baltimore, MD.

Lombard, D. B., B. P. Dash and S. Kumar. 2015. Acetyl-ed question in mitochondrial biology? EMBO Journal 34:2597-600. doi: 10.15252/embj.201592927. PMID: 26369717. PMC4641526.

Linford, N.J., Ro, J., Chung, B.Y., Pletcher, S.D., 2015. Gustatory and metabolic perception of nutrient stress in Drosophila. Proc Natl Acad Sci U S A Feb 24; 112, 2587-2592. doi: 10.1073/pnas.1401501112. Epub 2015 Feb 9. PMID: 25675472. PMC4345594.

Ma, S., S. H. Yim, S. G. Lee, E. B. Kim, S.-R. Lee, K.-T. Chang, R. Buffenstein, K. N. Lewis, T. J. Park, R. A. Miller, C. B. Clish, and V. N. Gladyshev. 2015. Organization of the mammalian metabolome according to organ function, lineage specialization and longevity. Cell Metabolism 22:332-343. PMID: 26244935.

Owczarczyk, A B., Schaller, M. A., Reed, M., Rasky, A. J., Lombard, D. B., and N. W. Lukacs. 2015. Sirtuin 1 Regulates Dendritic Cell Activation and Autophagy during Respiratory Syncytial Virus-Induced Immune Responses. Journal of Immunology 195:1637-46. doi: 10.4049/jimmunol.1500326. PMID: 26157176. PMC4530059.

Pickering, A. M., M. Lehr, and R. A. Miller. 2015. Lifespan of mice and primates correlates with immunoproteasome expression. J. Clin. Investigation 125:2059-2068. PMID: 25866968. PMC4463211.

Sadagurski, M., T. Landeryou, G. Cady, J. J. Kopchick, E. O. List, D. E. Berryman, A. Bartke, and R. A. Miller. 2015. Growth hormone modulates hypothalamic inflammation in long-lived pituitary dwarf mice. Aging Cell 14:1045-54. doi: 10.1111/acel.12382. PMID: 26268661.

Waterson M. J., T. P. Chan, and S. D. Pletcher. 2015. Adaptive physiological response to perceived scarcity as a mechanism of sensory modulation of lifespan. J. Gerontology A Biol. Sci 70:1088-91. doi: 10.1093/gerona/glv039. PMID: 25878032.

Zhang, B., R. Xiao, E. A. Ronan, Y. He, A.-L. Hsu, J. Liu, and X.Z. S. Xu. 2015. Environmental temperature differentially modulates C. elegans longevity through a thermosensitive channel. Cell Reports, 11:1414-1424. PMID: 26027928.