WP_WNT_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RHOA | Transforming protein RhoA | [1] | -1.74[2] | -1.90[3] | -1.88[4] | -1.66[5] | -1.18[6] | -1.64[7] |
2 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [8] | -1.19[9] | -1.19[10] | -0.68[11] | -0.42[12] | -0.42[13] | -1.29[14] |
3 | AKT1 | RAC-alpha serine/threonine-protein kinase | [15] | -0.72[16] | -0.62[17] | -1.90[18] | -0.49[19] | -0.44[20] | -0.56[21] |
4 | CTNNB1 | Catenin beta-1 | [22] | 0.82[23] | 0.64[24] | 1.34[25] | 0.32[26] | 0.57[27] | 0.79[28] |
5 | MYC | Myc proto-oncogene protein | [29] | -0.37[30] | -0.38[31] | -2.60[32] | -3.23[33] | -0.83[34] | -2.32[35] |
6 | CCND1 | G1/S-specific cyclin-D1 | [36] | 2.25[37] | 0.08[38] | 0.71[39] | 1.44[40] | -0.01[41] | 0.73[42] |
7 | CTBP1 | C-terminal-binding protein 1 | [43] | -0.75[44] | -0.30[45] | -0.22[46] | -0.03[47] | -0.96[48] | -0.59[49] |
8 | CSNK1A1 | Casein kinase I isoform alpha | [50] | -0.46[51] | -0.14[52] | -0.57[53] | 0.40[54] | 0.52[55] | 0.37[56] |
9 | CSNK1D | Casein kinase I isoform delta | [57] | 0.37[58] | 0.47[59] | 0.18[60] | 0.59[61] | 0.15[62] | -0.91[63] |
10 | GCKR | Glucokinase regulatory protein | [64] | -5.06[65] | -1.90[66] | -5.46[67] | -8.97[68] | -6.42[69] | 0.63[70] |
11 | DVL1 | Segment polarity protein dishevelled homolog DVL-1 | [71] | 0.01[72] | 0.79[73] | -0.53[74] | -0.37[75] | -0.31[76] | -1.08[77] |
12 | LRP5 | Low-density lipoprotein receptor-related protein 5 | [78] | 1.31[79] | 1.36[80] | 1.78[81] | 1.30[82] | -0.14[83] | 1.83[84] |
13 | MAPK1 | Mitogen-activated protein kinase 1 | [85] | 0.91[86] | 1.38[87] | 1.01[88] | 1.41[89] | 1.08[90] | 1.46[91] |
14 | GSK3A | Glycogen synthase kinase-3 alpha | [92] | -0.18[93] | -0.11[94] | -0.21[95] | -0.36[96] | 0.43[97] | -2.15[98] |
15 | RYK | Tyrosine-protein kinase RYK | [99] | 0.08[100] | 0.15[101] | -0.65[102] | -0.03[103] | 0.16[104] | -0.81[105] |
16 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [106] | -0.90[107] | 0.50[108] | 0.17[109] | 0.05[110] | 0.25[111] | -0.07[112] |
17 | ARRB2 | Beta-arrestin-2 | [113] | -0.63[114] | 0.09[115] | -0.16[116] | -1.75[117] | -0.93[118] | -1.19[119] |
18 | MAPK8 | Mitogen-activated protein kinase 8 | [120] | -2.24[121] | -0.50[122] | -1.83[123] | -1.34[124] | -1.46[125] | -0.83[126] |
19 | CSNK1E | Casein kinase I isoform epsilon | [127] | 0.57[128] | 0.53[129] | 0.99[130] | 0.03[131] | 1.12[132] | -1.14[133] |
20 | DVL3 | Segment polarity protein dishevelled homolog DVL-3 | [134] | 0.69[135] | 1.23[136] | 0.43[137] | 1.03[138] | 1.13[139] | -0.01[140] |
21 | TCF3 | Transcription factor E2-alpha | [141] | 1.34[142] | 0.99[143] | 1.38[144] | 0.94[145] | 1.13[146] | -1.46[147] |
22 | AXIN1 | Axin-1 | [148] | 0.55[149] | 1.20[150] | -0.56[151] | -9.13[152] | -0.26[153] | -0.97[154] |
23 | MAPK9 | Mitogen-activated protein kinase 9 | [155] | 0.43[156] | 0.99[157] | 0.84[158] | 1.28[159] | 0.76[160] | 0.19[161] |
24 | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | [162] | 0.26[163] | 0.88[164] | 0.27[165] | 0.46[166] | 1.48[167] | 0.33[168] |
25 | GSK3B | Glycogen synthase kinase-3 beta | [169] | 0.47[170] | 0.43[171] | 0.81[172] | 1.38[173] | 1.23[174] | 0.84[175] |
26 | CDK6 | Cyclin-dependent kinase 6 | [176] | 1.25[177] | 2.28[178] | 0.48[179] | 0.48[180] | 1.30[181] | 1.75[182] |
27 | AXIN2 | Axin-2 | [183] | 2.67[184] | 0.60[185] | -3.64[186] | -1.53[187] | -1.88[188] | -2.66[189] |
28 | PPARG | Peroxisome proliferator-activated receptor gamma | [190] | -0.89[191] | 1.06[192] | 1.37[193] | 0.41[194] | 0.40[195] | -0.70[196] |
29 | MTOR | Serine/threonine-protein kinase mTOR | [197] | 1.73[198] | 3.08[199] | 2.45[200] | 2.25[201] | 2.35[202] | 3.13[203] |
30 | TSC2 | Tuberin | [204] | 1.02[205] | 0.87[206] | 1.36[207] | 0.76[208] | 1.31[209] | 1.76[210] |
31 | PRKCA | Protein kinase C alpha type | [211] | 2.04[212] | 2.41[213] | 2.57[214] | 1.71[215] | 2.09[216] | 1.60[217] |
32 | TCF7L2 | Transcription factor 7-like 2 | [218] | 0.07[219] | 1.17[220] | 1.17[221] | 0.26[222] | 0.26[223] | 1.40[224] |
33 | NLK | Serine/threonine-protein kinase NLK | [225] | -0.53[226] | 0.37[227] | 0.66[228] | 0.28[229] | 0.06[230] | 0.49[231] |
34 | DVL2 | Segment polarity protein dishevelled homolog DVL-2 | [232] | 1.32[233] | 1.40[234] | 2.18[235] | 1.79[236] | 1.45[237] | -0.31[238] |
35 | LRP6 | Low-density lipoprotein receptor-related protein 6 | [239] | 1.02[240] | 2.02[241] | 3.17[242] | 1.42[243] | 1.99[244] | 4.46[245] |
36 | TSC1 | Hamartin | [246] | 1.09[247] | 2.08[248] | 2.03[249] | 1.62[250] | 1.85[251] | 2.44[252] |
37 | CSNK1G1 | Casein kinase I isoform gamma-1 | [253] | 1.03[254] | 1.58[255] | 1.80[256] | 2.01[257] | 1.94[258] | 1.35[259] |
38 | FRAT1 | Proto-oncogene FRAT1 | [260] | -0.11[261] | -0.02[262] | 1.89[263] | -2.99[264] | -1.78[265] | 0.15[266] |
39 | APC | Adenomatous polyposis coli protein | [267] | -0.23[268] | 1.77[269] | 1.41[270] | 1.79[271] | 2.45[272] | 3.42[273] |
40 | GJA1 | Gap junction alpha-1 protein | [274] | -3.65[275] | -3.03[276] | 3.99[277] | 4.52[278] | 4.63[279] | -0.66[280] |
41 | BCL9 | B-cell CLL/lymphoma 9 protein | [281] | 1.21[282] | 1.32[283] | 2.76[284] | 3.62[285] | 1.83[286] | 0.89[287] |
42 | PIP5K1B | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta | [288] | -0.36[289] | 2.38[290] | 1.71[291] | -4.27[292] | -5.83[293] | -3.21[294] |
43 | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2 | [295] | 1.79[296] | 3.38[297] | 2.59[298] | -0.26[299] | 0.72[300] | 2.97[301] |
44 | PRKCB | Protein kinase C beta type | [302] | -7.61[303] | -6.08[304] | [305] | 2.04[306] | -3.24[307] | 3.22[308] |
45 | TCF4 | Transcription factor 4 | [309] | -3.04[310] | -1.76[311] | 4.40[312] | 4.89[313] | 4.38[314] | 5.00[315] |
46 | TEK | Angiopoietin-1 receptor | [316] | -5.35[317] | -6.53[318] | -5.70[319] | 3.88[320] | 1.51[321] | 5.11[322] |
47 | ROR1 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | [323] | -1.39[324] | -1.76[325] | 3.99[326] | 5.22[327] | 4.93[328] | 1.41[329] |
48 | LEF1 | Lymphoid enhancer-binding factor 1 | [330] | 1.85[331] | -4.74[332] | 2.98[333] | 0.64[334] | -1.04[335] | 0.76[336] |
49 | PRKCG | Protein kinase C gamma type | [337] | -1.62[338] | -0.62[339] | -3.20[340] | -1.50[341] | -1.57[342] | [343] |
50 | ROR2 | Tyrosine-protein kinase transmembrane receptor ROR2 | [344] | -3.48[345] | [346] | -1.66[347] | 6.34[348] | 8.03[349] | 3.23[350] |
51 | SOX1 | Transcription factor SOX-1 | [351] | [352] | [353] | [354] | [355] | [356] | [357] |
52 | TPTEP2-CSNK1E | [358] | [359] | [360] | [361] | [362] | [363] | [364] | |
53 | MIR6808 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |