WP_VITAMIN_D_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GC Vitamin D-binding protein [1] -8.48[2] -8.10[3] -0.22[4] -7.30[5] -6.41[6] -0.17[7]
2 CYP27A1 Sterol 26-hydroxylase, mitochondrial [8] 1.07[9] 2.16[10] -2.48[11] 0.37[12] -0.56[13] 0.33[14]
3 DHCR7 7-dehydrocholesterol reductase [15] 2.14[16] 4.17[17] 2.87[18] 2.30[19] 3.16[20] 1.37[21]
4 RXRA Retinoic acid receptor RXR-alpha [22] 3.10[23] 3.20[24] 2.49[25] 4.94[26] 5.24[27] 2.39[28]
5 RXRB Retinoic acid receptor RXR-beta [29] 4.17[30] 4.80[31] 2.17[32] 6.51[33] 6.02[34] 0.36[35]
6 CYP2R1 Vitamin D 25-hydroxylase [36] -0.83[37] 1.27[38] 1.93[39] 3.60[40] 3.72[41] -0.63[42]
7 CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [43] 11.29[44] 6.73[45] -0.46[46] 9.04[47] 2.86[48] -6.85[49]
8 VDR Vitamin D3 receptor [50] 2.99[51] 3.72[52] 2.80[53] 7.26[54] 9.23[55] 0.72[56]
9 CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [57] 5.83[58] 7.57[59] 5.41[60] 6.12[61] 7.48[62] 1.92[63]
10 PTH Parathyroid hormone [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte GC
Mean 1.32e+03
Standard deviation 1.8e+03
Values 97 3.6e+03 2.9e+03 0.066 6.6
[2]
HepG2 GC
Mean 0.917
Standard deviation 0.12
Values 1 0.83
[3]
HepG2.C3A GC
Mean 0.862
Standard deviation 0.14
Values 0.76 0.96
[4]
HuH.7 GC
Mean 573
Standard deviation 3.1e+02
Values 4.4e+02 9.2e+02 3.6e+02
[5]
SNU475 GC
Mean 0.507
Standard deviation 0.13
Values 0.42 0.6
[6]
THLE GC
Mean 0.681
Standard deviation 0.23
Values 0.84 0.52
[7]
liver GC
Mean 1.41e+03
Standard deviation 6.2e+02
Values 8.1e+02 1.1e+03 2.2e+03 1.5e+03
[8]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 18 3.7e+02 2.1e+02 62 8
[9]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 82 59
[10]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 90 1.3e+02
[11]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 8.9 21 7.2
[12]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 9.4 12
[13]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[14]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 1.1e+02 1.2e+02 3.3e+02 2.5e+02
[15]
ref_hepatocyte DHCR7
Mean 31.8
Standard deviation 19
Values 23 59 43 21 13
[16]
HepG2 DHCR7
Mean 34.7
Standard deviation 11
Values 43 27
[17]
HepG2.C3A DHCR7
Mean 103
Standard deviation 68
Values 54 1.5e+02
[18]
HuH.7 DHCR7
Mean 117
Standard deviation 29
Values 90 1.5e+02 1.1e+02
[19]
SNU475 DHCR7
Mean 9.4
Standard deviation 1.9
Values 8 11
[20]
THLE DHCR7
Mean 12.4
Standard deviation 3.1
Values 10 15
[21]
liver DHCR7
Mean 98.2
Standard deviation 72
Values 68 50 69 2.1e+02
[22]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 9.4 18 22 15 7.5
[23]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 29 33
[24]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 20 28
[25]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 30 51 42
[26]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 21 33
[27]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[28]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.2e+02 72 1.3e+02 49
[29]
ref_hepatocyte RXRB
Mean 5.01
Standard deviation 2.9
Values 7.3 7 7.1 1.6 2.1
[30]
HepG2 RXRB
Mean 22.3
Standard deviation 2
Values 24 21
[31]
HepG2.C3A RXRB
Mean 24.9
Standard deviation 2.8
Values 23 27
[32]
HuH.7 RXRB
Mean 11.3
Standard deviation 2.4
Values 14 10 9.8
[33]
SNU475 RXRB
Mean 27.5
Standard deviation 6.1
Values 23 32
[34]
THLE RXRB
Mean 14.2
Standard deviation 0.3
Values 14 14
[35]
liver RXRB
Mean 7.69
Standard deviation 0.73
Values 8.2 6.6 8 7.9
[36]
ref_hepatocyte CYP2R1
Mean 2.89
Standard deviation 1.8
Values 3.6 2.3 3.9 0 4.7
[37]
HepG2 CYP2R1
Mean 0.405
Standard deviation 0.2
Values 0.27 0.54
[38]
HepG2.C3A CYP2R1
Mean 1.25
Standard deviation 0.41
Values 0.95 1.5
[39]
HuH.7 CYP2R1
Mean 5.56
Standard deviation 0.93
Values 6.4 5.8 4.6
[40]
SNU475 CYP2R1
Mean 2.12
Standard deviation 0.069
Values 2.1 2.2
[41]
THLE CYP2R1
Mean 1.67
Standard deviation 0.39
Values 1.9 1.4
[42]
liver CYP2R1
Mean 2.24
Standard deviation 0.78
Values 2 1.6 3.4 2
[43]
ref_hepatocyte CYP24A1
Mean 0.344
Standard deviation 0.69
Values 0 0 0 1.6 0.15
[44]
HepG2 CYP24A1
Mean 215
Standard deviation 90
Values 1.5e+02 2.8e+02
[45]
HepG2.C3A CYP24A1
Mean 6.56
Standard deviation 2.9
Values 8.6 4.5
[46]
HuH.7 CYP24A1
Mean 0.126
Standard deviation 0.11
Values 0.019 0.24 0.11
[47]
SNU475 CYP24A1
Mean 10.9
Standard deviation 10
Values 18 3.8
[48]
THLE CYP24A1
Mean 0.109
Standard deviation 0.079
Values 0.053 0.16
[49]
liver CYP24A1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[50]
ref_hepatocyte VDR
Mean 0.333
Standard deviation 0.23
Values 0.19 0.39 0.41 0.038 0.63
[51]
HepG2 VDR
Mean 0.657
Standard deviation 0.019
Values 0.64 0.67
[52]
HepG2.C3A VDR
Mean 0.783
Standard deviation 0.23
Values 0.94 0.62
[53]
HuH.7 VDR
Mean 1.17
Standard deviation 0.57
Values 1.3 0.56 1.7
[54]
SNU475 VDR
Mean 3.08
Standard deviation 3
Values 5.2 0.97
[55]
THLE VDR
Mean 8.71
Standard deviation 1.4
Values 7.8 9.7
[56]
liver VDR
Mean 0.658
Standard deviation 0.17
Values 0.54 0.56 0.63 0.9
[57]
ref_hepatocyte CYP27B1
Mean 0.0505
Standard deviation 0.082
Values 0.19 0.065 0 0 0
[58]
HepG2 CYP27B1
Mean 0.715
Standard deviation 0.14
Values 0.81 0.62
[59]
HepG2.C3A CYP27B1
Mean 1.72
Standard deviation 0.25
Values 1.5 1.9
[60]
HuH.7 CYP27B1
Mean 1.08
Standard deviation 0.18
Values 1.3 0.89 1.1
[61]
SNU475 CYP27B1
Mean 0.211
Standard deviation 0.1
Values 0.28 0.14
[62]
THLE CYP27B1
Mean 0.395
Standard deviation 0.14
Values 0.5 0.29
[63]
liver CYP27B1
Mean 0.228
Standard deviation 0.17
Values 0.24 0.14 0.071 0.46
[64]
ref_hepatocyte PTH
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 PTH
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A PTH
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 PTH
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 PTH
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE PTH
Mean 0
Standard deviation 0
Values 0 0
[70]
liver PTH
Mean 0.026
Standard deviation 0.0021
Values 0.026 0.029 0.024 0.026