WP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | P4HB | Protein disulfide-isomerase | [1] | 0.36[2] | 0.10[3] | -0.13[4] | -0.62[5] | -0.83[6] | 0.69[7] |
2 | PPIB | Peptidyl-prolyl cis-trans isomerase B | [8] | -2.56[9] | -2.43[10] | -2.32[11] | -2.62[12] | -3.42[13] | -2.44[14] |
3 | SERPINF1 | Pigment epithelium-derived factor | [15] | -1.23[16] | -0.48[17] | -1.51[18] | -7.47[19] | -8.21[20] | -0.59[21] |
4 | PLOD2 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | [22] | -1.03[23] | -0.78[24] | -0.50[25] | -0.37[26] | -0.16[27] | -2.59[28] |
5 | PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | [29] | 2.79[30] | 3.20[31] | 2.44[32] | 1.98[33] | 2.14[34] | 0.81[35] |
6 | P4HA1 | Prolyl 4-hydroxylase subunit alpha-1 | [36] | 2.28[37] | 2.75[38] | 2.40[39] | 2.67[40] | 1.95[41] | 0.99[42] |
7 | MBTPS1 | Membrane-bound transcription factor site-1 protease | [43] | 1.91[44] | 1.64[45] | 2.08[46] | 2.34[47] | 2.06[48] | 1.47[49] |
8 | LRP5 | Low-density lipoprotein receptor-related protein 5 | [50] | 2.44[51] | 2.07[52] | 3.13[53] | 2.69[54] | 0.89[55] | 2.30[56] |
9 | SERPINH1 | Serpin H1 | [57] | 2.43[58] | 1.94[59] | 1.60[60] | 4.57[61] | 3.51[62] | -0.22[63] |
10 | TMEM38B | Trimeric intracellular cation channel type B | [64] | -0.56[65] | -0.03[66] | 0.91[67] | -0.23[68] | -0.10[69] | -0.09[70] |
11 | P4HA2 | Prolyl 4-hydroxylase subunit alpha-2 | [71] | 1.76[72] | 0.65[73] | 0.42[74] | 2.34[75] | 2.48[76] | -1.36[77] |
12 | MIA3 | Transport and Golgi organization protein 1 homolog | [78] | -0.19[79] | 0.53[80] | 2.37[81] | 2.26[82] | 1.20[83] | 2.35[84] |
13 | CRTAP | Cartilage-associated protein | [85] | 1.61[86] | 1.22[87] | 3.91[88] | 3.60[89] | 3.25[90] | 1.09[91] |
14 | BMP1 | Bone morphogenetic protein 1 | [92] | 1.06[93] | -0.52[94] | -0.75[95] | 3.06[96] | 2.14[97] | 1.07[98] |
15 | MBTPS2 | Membrane-bound transcription factor site-2 protease | [99] | 1.27[100] | 1.54[101] | 2.77[102] | 3.04[103] | 2.62[104] | 1.70[105] |
16 | FKBP10 | Peptidyl-prolyl cis-trans isomerase FKBP10 | [106] | 4.88[107] | 4.50[108] | 0.28[109] | 1.12[110] | 4.89[111] | -1.19[112] |
17 | TNFSF11 | Tumor necrosis factor ligand superfamily member 11 | [113] | [114] | [115] | [116] | -9.59[117] | -4.44[118] | -3.61[119] |
18 | LRP6 | Low-density lipoprotein receptor-related protein 6 | [120] | 2.15[121] | 2.73[122] | 4.52[123] | 2.81[124] | 3.02[125] | 4.93[126] |
19 | TNFRSF11 | Tumor necrosis factor receptor superfamily member 11A | [127] | 2.37[128] | 1.06[129] | -0.34[130] | 0.32[131] | 1.32[132] | -1.09[133] |
20 | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 | [134] | 3.47[135] | 3.27[136] | 4.86[137] | 3.80[138] | 4.34[139] | 4.80[140] |
21 | COL1A1 | Collagen alpha-1(I) chain | [141] | 5.07[142] | -2.53[143] | -0.27[144] | 7.95[145] | 9.16[146] | 6.50[147] |
22 | COL1A2 | Collagen alpha-2(I) chain | [148] | -5.82[149] | -5.84[150] | -2.91[151] | 5.92[152] | 5.63[153] | 6.57[154] |
23 | TNFRSF11 | Tumor necrosis factor receptor superfamily member 11B | [155] | -3.09[156] | -3.72[157] | 3.05[158] | 2.99[159] | 3.04[160] | 2.93[161] |
24 | FZD1 | Frizzled-1 | [162] | 1.88[163] | -0.17[164] | 3.95[165] | 3.36[166] | 4.16[167] | 2.94[168] |
25 | ADAMTS2 | A disintegrin and metalloproteinase with thrombospondin motifs 2 | [169] | 1.72[170] | 2.45[171] | -3.40[172] | 3.51[173] | 5.96[174] | 5.86[175] |
26 | LOX | Protein-lysine 6-oxidase | [176] | 8.14[177] | 8.56[178] | 9.64[179] | 6.19[180] | 9.95[181] | 3.68[182] |
27 | CREB3L1 | Cyclic AMP-responsive element-binding protein 3-like protein 1 | [183] | 0.32[184] | -2.69[185] | 7.43[186] | 6.26[187] | 6.21[188] | -0.09[189] |
28 | IFITM5 | Interferon-induced transmembrane protein 5 | [190] | [191] | [192] | -1.55[193] | [194] | [195] | -2.08[196] |
29 | COLGALT1 | Procollagen galactosyltransferase 1 | [197] | [198] | [199] | [200] | [201] | [202] | [203] |
30 | WNT1 | Proto-oncogene Wnt-1 | [204] | [205] | [206] | [207] | [208] | [209] | [210] |
31 | SP7 | Transcription factor Sp7 | [211] | [212] | [213] | [214] | [215] | [216] | [217] |
32 | P3H1 | Prolyl 3-hydroxylase 1 | [218] | [219] | [220] | [221] | [222] | [223] | [224] |
33 | P3H2 | Prolyl 3-hydroxylase 2 | [225] | [226] | [227] | [228] | [229] | [230] | [231] |