WP_TYPE_II_INTERFERON_SIGNALING_IFNG | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HLA-B | HLA class I histocompatibility antigen, B-73 alpha chain | [1] | -2.11[2] | -3.04[3] | -7.24[4] | 0.09[5] | -0.37[6] | -1.23[7] |
2 | IFI6 | Interferon alpha-inducible protein 6 | [8] | -1.60[9] | -5.01[10] | -3.70[11] | -2.46[12] | -2.99[13] | 0.33[14] |
3 | ISG15 | Ubiquitin-like protein ISG15 | [15] | -1.27[16] | -0.62[17] | -1.60[18] | -3.61[19] | -4.20[20] | -2.29[21] |
4 | IFNGR1 | Interferon gamma receptor 1 | [22] | 1.67[23] | 0.95[24] | -0.37[25] | -0.69[26] | -0.39[27] | -0.20[28] |
5 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [29] | 1.33[30] | 2.17[31] | 2.26[32] | 0.58[33] | 1.76[34] | 1.37[35] |
6 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [36] | 0.81[37] | 0.30[38] | 1.54[39] | 2.22[40] | 0.50[41] | 1.06[42] |
7 | GBP1 | Guanylate-binding protein 1 | [43] | -3.62[44] | -8.23[45] | -5.17[46] | 0.73[47] | -0.52[48] | -0.11[49] |
8 | IFNGR2 | Interferon gamma receptor 2 | [50] | 0.85[51] | 1.82[52] | -0.07[53] | -1.68[54] | 0.15[55] | -0.47[56] |
9 | JAK1 | Tyrosine-protein kinase JAK1 | [57] | 1.40[58] | 1.29[59] | 1.61[60] | 0.32[61] | 1.51[62] | 1.64[63] |
10 | PSMB9 | Proteasome subunit beta type-9 | [64] | -2.11[65] | -4.43[66] | -6.58[67] | 0.17[68] | -1.53[69] | -1.72[70] |
11 | ICAM1 | Intercellular adhesion molecule 1 | [71] | 2.79[72] | 2.56[73] | 3.11[74] | -0.12[75] | 2.60[76] | -0.30[77] |
12 | IRF9 | Interferon regulatory factor 9 | [78] | 0.07[79] | -1.35[80] | -0.94[81] | -0.68[82] | -1.17[83] | 0.02[84] |
13 | OAS1 | 2'-5'-oligoadenylate synthase 1 | [85] | 0.26[86] | -2.22[87] | -7.89[88] | -3.06[89] | -3.97[90] | -0.32[91] |
14 | SOCS3 | Suppressor of cytokine signaling 3 | [92] | -3.25[93] | -3.26[94] | -1.41[95] | -1.11[96] | -1.64[97] | 0.24[98] |
15 | TAP1 | Antigen peptide transporter 1 | [99] | 0.77[100] | 0.16[101] | -3.41[102] | 1.28[103] | 0.19[104] | -0.56[105] |
16 | IRF2 | Interferon regulatory factor 2 | [106] | -0.21[107] | 0.59[108] | -0.44[109] | -1.41[110] | -0.80[111] | -0.23[112] |
17 | IRF1 | Interferon regulatory factor 1 | [113] | 0.38[114] | 0.31[115] | 0.59[116] | 0.95[117] | 0.49[118] | 0.94[119] |
18 | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase | [120] | 0.57[121] | 0.93[122] | -0.91[123] | 0.70[124] | 0.76[125] | 0.90[126] |
19 | STAT2 | Signal transducer and activator of transcription 2 | [127] | 0.92[128] | 2.69[129] | 1.98[130] | 1.22[131] | 1.22[132] | 3.14[133] |
20 | IFIT2 | Interferon-induced protein with tetratricopeptide repeats 2 | [134] | -4.62[135] | -5.06[136] | -1.01[137] | -1.75[138] | -1.43[139] | 0.37[140] |
21 | PRKCD | Protein kinase C delta type | [141] | 1.99[142] | 2.64[143] | 2.25[144] | -0.81[145] | 0.89[146] | -0.96[147] |
22 | IL1B | Interleukin-1 beta | [148] | -7.81[149] | -7.27[150] | -2.81[151] | -3.90[152] | 2.23[153] | -5.09[154] |
23 | IRF8 | Interferon regulatory factor 8 | [155] | -5.94[156] | -4.45[157] | 4.30[158] | -4.74[159] | -1.12[160] | 0.79[161] |
24 | SOCS1 | Suppressor of cytokine signaling 1 | [162] | -0.56[163] | 0.71[164] | 1.11[165] | -2.10[166] | -2.94[167] | -1.35[168] |
25 | SPI1 | Transcription factor PU.1 | [169] | -8.27[170] | [171] | -8.83[172] | -9.96[173] | -10.23[174] | -0.46[175] |
26 | CXCL10 | C-X-C motif chemokine 10 | [176] | -8.26[177] | -5.54[178] | -0.29[179] | -1.87[180] | -8.92[181] | -2.27[182] |
27 | CYBB | Cytochrome b-245 heavy chain | [183] | [184] | [185] | -8.79[186] | -4.78[187] | -9.79[188] | 3.16[189] |
28 | JAK2 | Tyrosine-protein kinase JAK2 | [190] | 1.11[191] | 1.51[192] | 1.20[193] | 0.45[194] | 1.59[195] | 2.82[196] |
29 | NOS2 | Nitric oxide synthase, inducible | [197] | 0.91[198] | [199] | -4.80[200] | -5.17[201] | -5.51[202] | -7.20[203] |
30 | IRF4 | Interferon regulatory factor 4 | [204] | -3.94[205] | -3.20[206] | -3.69[207] | -4.61[208] | -5.18[209] | 0.72[210] |
31 | REG1A | Lithostathine-1-alpha | [211] | [212] | [213] | 0.01[214] | [215] | [216] | -2.27[217] |
32 | CXCL9 | C-X-C motif chemokine 9 | [218] | -6.80[219] | [220] | -2.86[221] | -2.28[222] | [223] | 0.50[224] |
33 | IFNG | Interferon gamma | [225] | [226] | [227] | [228] | -1.00[229] | [230] | -2.19[231] |
34 | CIITA | MHC class II transactivator | [232] | -1.50[233] | -1.27[234] | -3.05[235] | -0.97[236] | 0.73[237] | 3.02[238] |
35 | IFNA2 | Interferon alpha-2 | [239] | [240] | [241] | [242] | [243] | [244] | [245] |
36 | H4C14 | [246] | [247] | [248] | [249] | [250] | [251] | [252] | |
37 | IFNB1 | Interferon beta | [253] | [254] | [255] | [256] | [257] | [258] | [259] |