WP_TYPE_II_DIABETES_MELLITUS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SLC2A2 Solute carrier family 2, facilitated glucose transporter member 2 [1] -3.26[2] -3.29[3] -2.47[4] -6.33[5] -10.71[6] 0.05[7]
2 SURF1 Surfeit locus protein 1 [8] -1.91[9] -2.45[10] -2.10[11] -1.47[12] -1.69[13] -2.39[14]
3 MAPK1 Mitogen-activated protein kinase 1 [15] 1.65[16] 0.98[17] 0.97[18] 2.30[19] 1.93[20] -0.02[21]
4 GK Glycerol kinase [22] 0.37[23] 1.69[24] 0.69[25] -3.06[26] -0.91[27] 0.21[28]
5 PRKCZ Protein kinase C zeta type [29] 0.41[30] -0.01[31] -1.85[32] -1.85[33] -4.06[34] -3.43[35]
6 MAPK8 Mitogen-activated protein kinase 8 [36] -1.51[37] -0.90[38] -1.86[39] -0.45[40] -0.61[41] -2.30[42]
7 INSR Insulin receptor [43] 0.40[44] 0.24[45] 1.84[46] -2.63[47] -0.05[48] 2.21[49]
8 PHKA2 Phosphorylase b kinase regulatory subunit alpha, liver isoform [50] 1.21[51] 1.95[52] 1.61[53] -0.10[54] -0.03[55] 1.19[56]
9 PRKCD Protein kinase C delta type [57] 1.04[58] 0.48[59] 0.12[60] -0.06[61] 1.09[62] -2.86[63]
10 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [64] 0.46[65] -0.29[66] -0.02[67] 0.71[68] 0.78[69] -0.61[70]
11 MTOR Serine/threonine-protein kinase mTOR [71] 2.47[72] 2.68[73] 2.41[74] 3.13[75] 3.20[76] 1.66[77]
12 IRS1 Insulin receptor substrate 1 [78] 2.03[79] 0.67[80] 2.26[81] 2.15[82] 1.72[83] 0.32[84]
13 SOCS4 Suppressor of cytokine signaling 4 [85] 0.58[86] 0.57[87] 1.24[88] 2.23[89] 2.83[90] -0.03[91]
14 SLC2A4 Solute carrier family 2, facilitated glucose transporter member 4 [92] 1.77[93] 1.20[94] 1.99[95] -1.68[96] -2.43[97] -0.35[98]
15 KCNJ11 ATP-sensitive inward rectifier potassium channel 11 [99] 0.24[100] -1.07[101] -1.47[102] -0.76[103] -1.51[104] -2.24[105]
16 PIK3R5 Phosphoinositide 3-kinase regulatory subunit 5 [106] -7.23[107] [108] -3.23[109] -3.47[110] -3.15[111] 0.55[112]
17 TNF Tumor necrosis factor [113] 1.04[114] -1.90[115] -6.33[116] -1.77[117] -5.01[118] -3.68[119]
18 MAFA Transcription factor MafA [120] 0.35[121] -2.10[122] -1.21[123] -2.99[124] -0.99[125] [126]
19 ADIPOQ Adiponectin [127] -1.58[128] -2.18[129] -2.24[130] -0.42[131] -1.44[132] -2.54[133]
20 INS-IGF2 Insulin, isoform 2 [134] -4.64[135] -3.44[136] -5.12[137] [138] [139] -1.58[140]
21 PDX1 Pancreas/duodenum homeobox protein 1 [141] 0.33[142] -3.15[143] 4.93[144] -1.82[145] [146] 0.65[147]
22 CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A [148] -2.16[149] -1.62[150] 1.43[151] 5.38[152] 3.43[153] 2.49[154]
[1]
ref_hepatocyte SLC2A2
Mean 50.4
Standard deviation 77
Values 0.5 1.9e+02 39 3.6 23
[2]
HepG2 SLC2A2
Mean 12.1
Standard deviation 6.3
Values 17 7.6
[3]
HepG2.C3A SLC2A2
Mean 18.4
Standard deviation 9.8
Values 25 11
[4]
HuH.7 SLC2A2
Mean 27.9
Standard deviation 5.4
Values 22 32 29
[5]
SNU475 SLC2A2
Mean 0.843
Standard deviation 0.21
Values 0.69 0.99
[6]
THLE SLC2A2
Mean 0.0458
Standard deviation 0.027
Values 0.065 0.027
[7]
liver SLC2A2
Mean 257
Standard deviation 32
Values 2.9e+02 2.6e+02 2.5e+02 2.2e+02
[8]
ref_hepatocyte SURF1
Mean 25.5
Standard deviation 23
Values 4.8 53 48 9.2 12
[9]
HepG2 SURF1
Mean 15.7
Standard deviation 1.6
Values 15 17
[10]
HepG2.C3A SURF1
Mean 16.8
Standard deviation 3.5
Values 14 19
[11]
HuH.7 SURF1
Mean 18.3
Standard deviation 3.6
Values 22 15 18
[12]
SNU475 SURF1
Mean 12.4
Standard deviation 0.63
Values 12 13
[13]
THLE SURF1
Mean 12.1
Standard deviation 1.5
Values 11 13
[14]
liver SURF1
Mean 24
Standard deviation 22
Values 7.5 4.3 50 35
[15]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[16]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[17]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[18]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[19]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[20]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[21]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[22]
ref_hepatocyte GK
Mean 9.96
Standard deviation 1.5
Values 9.2 11 11 10 7.8
[23]
HepG2 GK
Mean 29.7
Standard deviation 12
Values 21 38
[24]
HepG2.C3A GK
Mean 115
Standard deviation 44
Values 85 1.5e+02
[25]
HuH.7 GK
Mean 49.4
Standard deviation 1.2
Values 50 50 48
[26]
SNU475 GK
Mean 1.61
Standard deviation 0.1
Values 1.7 1.5
[27]
THLE GK
Mean 8.1
Standard deviation 0.54
Values 7.7 8.5
[28]
liver GK
Mean 56.7
Standard deviation 16
Values 53 46 47 81
[29]
ref_hepatocyte PRKCZ
Mean 7.98
Standard deviation 3.5
Values 6.7 6.6 8.2 14 4.6
[30]
HepG2 PRKCZ
Mean 24.4
Standard deviation 2
Values 23 26
[31]
HepG2.C3A PRKCZ
Mean 28.4
Standard deviation 7.3
Values 23 33
[32]
HuH.7 PRKCZ
Mean 6.79
Standard deviation 1.7
Values 5.5 8.8 6.1
[33]
SNU475 PRKCZ
Mean 2.98
Standard deviation 1.9
Values 1.6 4.4
[34]
THLE PRKCZ
Mean 0.727
Standard deviation 0.035
Values 0.75 0.7
[35]
liver PRKCZ
Mean 3.64
Standard deviation 0.55
Values 3.5 3.9 2.9 4.2
[36]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[37]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[38]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[39]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[40]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[41]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[42]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[43]
ref_hepatocyte INSR
Mean 5.73
Standard deviation 1.4
Values 4.1 7.7 5.3 6.5 5
[44]
HepG2 INSR
Mean 17.4
Standard deviation 4.9
Values 14 21
[45]
HepG2.C3A INSR
Mean 24.3
Standard deviation 6.7
Values 20 29
[46]
HuH.7 INSR
Mean 62.9
Standard deviation 26
Values 39 91 58
[47]
SNU475 INSR
Mean 1.24
Standard deviation 0.29
Values 1 1.4
[48]
THLE INSR
Mean 8.45
Standard deviation 0.32
Values 8.2 8.7
[49]
liver INSR
Mean 131
Standard deviation 15
Values 1.3e+02 1.5e+02 1.4e+02 1.1e+02
[50]
ref_hepatocyte PHKA2
Mean 4.97
Standard deviation 3.9
Values 1.2 8.3 10 3 2.3
[51]
HepG2 PHKA2
Mean 26.5
Standard deviation 4.1
Values 29 24
[52]
HepG2.C3A PHKA2
Mean 69
Standard deviation 22
Values 53 85
[53]
HuH.7 PHKA2
Mean 46.4
Standard deviation 20
Values 34 69 37
[54]
SNU475 PHKA2
Mean 6.24
Standard deviation 1.9
Values 4.9 7.6
[55]
THLE PHKA2
Mean 7.41
Standard deviation 0.35
Values 7.2 7.7
[56]
liver PHKA2
Mean 55.8
Standard deviation 17
Values 57 76 36 54
[57]
ref_hepatocyte PRKCD
Mean 3.58
Standard deviation 2
Values 5.5 1.5 2.1 5.9 2.9
[58]
HepG2 PRKCD
Mean 16.9
Standard deviation 3.4
Values 15 19
[59]
HepG2.C3A PRKCD
Mean 17.9
Standard deviation 3.3
Values 16 20
[60]
HuH.7 PRKCD
Mean 12
Standard deviation 0.2
Values 12 12 12
[61]
SNU475 PRKCD
Mean 4.64
Standard deviation 0.32
Values 4.9 4.4
[62]
THLE PRKCD
Mean 11.6
Standard deviation 1.2
Values 11 12
[63]
liver PRKCD
Mean 2.43
Standard deviation 1
Values 2.3 1.4 3.9 2.2
[64]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[65]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[66]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[67]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[68]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[69]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[70]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[71]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[72]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[73]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[74]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[75]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[76]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[77]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[78]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 2.7 4.7 2.1 4.3 1.5
[79]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 23 35
[80]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 13 22
[81]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 37 48 49
[82]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 22 15
[83]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[84]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 22 18 23 12
[85]
ref_hepatocyte SOCS4
Mean 2.14
Standard deviation 1.9
Values 0.46 0.67 1.1 4.4 4.1
[86]
HepG2 SOCS4
Mean 7.35
Standard deviation 2.4
Values 9 5.7
[87]
HepG2.C3A SOCS4
Mean 11.4
Standard deviation 2.1
Values 13 9.9
[88]
HuH.7 SOCS4
Mean 15.4
Standard deviation 2.2
Values 15 14 18
[89]
SNU475 SOCS4
Mean 13.5
Standard deviation 0.85
Values 14 13
[90]
THLE SOCS4
Mean 23.2
Standard deviation 3.1
Values 25 21
[91]
liver SOCS4
Mean 10.3
Standard deviation 1.7
Values 9.5 13 9.5 9.4
[92]
ref_hepatocyte SLC2A4
Mean 0.539
Standard deviation 0.49
Values 0.027 1.1 0.48 1 0.1
[93]
HepG2 SLC2A4
Mean 4.23
Standard deviation 1.9
Values 2.9 5.5
[94]
HepG2.C3A SLC2A4
Mean 4.46
Standard deviation 1.2
Values 3.6 5.3
[95]
HuH.7 SLC2A4
Mean 6.56
Standard deviation 1.3
Values 7.1 5.1 7.5
[96]
SNU475 SLC2A4
Mean 0.226
Standard deviation 0.054
Values 0.19 0.26
[97]
THLE SLC2A4
Mean 0.153
Standard deviation 0.043
Values 0.18 0.12
[98]
liver SLC2A4
Mean 2.08
Standard deviation 1.4
Values 1.3 1 4 2
[99]
ref_hepatocyte KCNJ11
Mean 0.422
Standard deviation 0.31
Values 0.53 0.42 0.87 0.038 0.25
[100]
HepG2 KCNJ11
Mean 1.15
Standard deviation 0.64
Values 0.7 1.6
[101]
HepG2.C3A KCNJ11
Mean 0.724
Standard deviation 0.45
Values 0.41 1
[102]
HuH.7 KCNJ11
Mean 0.468
Standard deviation 0.1
Values 0.49 0.36 0.56
[103]
SNU475 KCNJ11
Mean 0.336
Standard deviation 0.023
Values 0.32 0.35
[104]
THLE KCNJ11
Mean 0.227
Standard deviation 0.065
Values 0.27 0.18
[105]
liver KCNJ11
Mean 0.44
Standard deviation 0.18
Values 0.52 0.66 0.33 0.26
[106]
ref_hepatocyte PIK3R5
Mean 0.373
Standard deviation 0.52
Values 1.3 0.3 0.29 0 0
[107]
HepG2 PIK3R5
Mean 0.00573
Standard deviation 0.0081
Values 0 0.011
[108]
HepG2.C3A PIK3R5
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 PIK3R5
Mean 0.122
Standard deviation 0.035
Values 0.16 0.12 0.09
[110]
SNU475 PIK3R5
Mean 0.0452
Standard deviation 0.051
Values 0.081 0.0093
[111]
THLE PIK3R5
Mean 0.0642
Standard deviation 0.068
Values 0.11 0.016
[112]
liver PIK3R5
Mean 2.68
Standard deviation 0.95
Values 3.9 2.9 1.9 2
[113]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[114]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[115]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[116]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[117]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[118]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[119]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[120]
ref_hepatocyte MAFA
Mean 0.0832
Standard deviation 0.19
Values 0.42 0 0 0 0
[121]
HepG2 MAFA
Mean 0.245
Standard deviation 0.16
Values 0.13 0.36
[122]
HepG2.C3A MAFA
Mean 0.0696
Standard deviation 0.053
Values 0.032 0.11
[123]
HuH.7 MAFA
Mean 0.11
Standard deviation 0.033
Values 0.075 0.14 0.11
[124]
SNU475 MAFA
Mean 0.0141
Standard deviation 0.013
Values 0.0051 0.023
[125]
THLE MAFA
Mean 0.0639
Standard deviation 0.015
Values 0.053 0.074
[126]
liver MAFA
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte ADIPOQ
Mean 0.0714
Standard deviation 0.076
Values 0.073 0.041 0.2 0.045 0
[128]
HepG2 ADIPOQ
Mean 0.0551
Standard deviation 0.011
Values 0.047 0.063
[129]
HepG2.C3A ADIPOQ
Mean 0.0565
Standard deviation 0.011
Values 0.064 0.049
[130]
HuH.7 ADIPOQ
Mean 0.0463
Standard deviation 0.036
Values 0.075 0.0064 0.057
[131]
SNU475 ADIPOQ
Mean 0.0718
Standard deviation 0.049
Values 0.11 0.037
[132]
THLE ADIPOQ
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[133]
liver ADIPOQ
Mean 0.0603
Standard deviation 0.041
Values 0.093 0.071 0 0.077
[134]
ref_hepatocyte INS-IGF2
Mean 0.0309
Standard deviation 0.069
Values 0 0.15 0 0 0
[135]
HepG2 INS-IGF2
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[136]
HepG2.C3A INS-IGF2
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[137]
HuH.7 INS-IGF2
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[138]
SNU475 INS-IGF2
Mean 0
Standard deviation 0
Values 0 0
[139]
THLE INS-IGF2
Mean 0
Standard deviation 0
Values 0 0
[140]
liver INS-IGF2
Mean 0.0507
Standard deviation 0.054
Values 0.013 0.014 0.047 0.13
[141]
ref_hepatocyte PDX1
Mean 0.0133
Standard deviation 0.02
Values 0.022 0 0 0.045 0
[142]
HepG2 PDX1
Mean 0.0386
Standard deviation 0.006
Values 0.043 0.034
[143]
HepG2.C3A PDX1
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[144]
HuH.7 PDX1
Mean 1.24
Standard deviation 0.28
Values 1.5 0.93 1.3
[145]
SNU475 PDX1
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[146]
THLE PDX1
Mean 0
Standard deviation 0
Values 0 0
[147]
liver PDX1
Mean 0.103
Standard deviation 0.045
Values 0.16 0.057 0.12 0.077
[148]
ref_hepatocyte CACNA1A
Mean 0.00833
Standard deviation 0.012
Values 0 0.024 0.017 0 0
[149]
HepG2 CACNA1A
Mean 0.00429
Standard deviation 0.0061
Values 0.0086 0
[150]
HepG2.C3A CACNA1A
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[151]
HuH.7 CACNA1A
Mean 0.0688
Standard deviation 0.035
Values 0.1 0.071 0.033
[152]
SNU475 CACNA1A
Mean 0.467
Standard deviation 0.15
Values 0.36 0.58
[153]
THLE CACNA1A
Mean 0.137
Standard deviation 0.066
Values 0.18 0.09
[154]
liver CACNA1A
Mean 0.231
Standard deviation 0.021
Values 0.23 0.26 0.24 0.21