WP_TRYPTOPHAN_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2E1 Cytochrome P450 2E1 [1] -11.70[2] -11.99[3] -9.65[4] -13.74[5] -11.02[6] -0.55[7]
2 ALDH2 Aldehyde dehydrogenase, mitochondrial [8] -0.11[9] -1.14[10] -1.72[11] -1.75[12] -0.58[13] -0.60[14]
3 ALDH1A1 Retinal dehydrogenase 1 [15] 1.30[16] 0.31[17] 2.43[18] 2.82[19] -4.39[20] -1.54[21]
4 CYP3A4 Cytochrome P450 3A4 [22] -8.95[23] -9.22[24] -11.84[25] -13.82[26] -11.12[27] 0.58[28]
5 ECHS1 Enoyl-CoA hydratase, mitochondrial [29] 0.15[30] 0.56[31] -0.57[32] -1.32[33] 0.05[34] -0.33[35]
6 ACAT1 Acetyl-CoA acetyltransferase, mitochondrial [36] 0.32[37] 0.05[38] -2.03[39] -0.20[40] -0.15[41] 0.44[42]
7 AOX1 Aldehyde oxidase [43] -0.87[44] -1.20[45] -8.50[46] -2.62[47] 0.18[48] 2.10[49]
8 DHCR24 Delta(24)-sterol reductase [50] 2.23[51] 2.98[52] 2.41[53] 0.10[54] 2.03[55] 1.39[56]
9 TDO2 Tryptophan 2,3-dioxygenase [57] -11.91[58] -10.10[59] -7.40[60] -5.19[61] -6.51[62] 0.96[63]
10 CAT Catalase [64] 0.74[65] 0.29[66] -0.12[67] -0.55[68] -0.02[69] 0.34[70]
11 KYNU Kynureninase [71] -0.07[72] 0.37[73] -3.43[74] -1.64[75] -1.28[76] -2.71[77]
12 HSD17B10 3-hydroxyacyl-CoA dehydrogenase type-2 [78] 0.08[79] -0.33[80] -1.00[81] 0.13[82] 2.07[83] -1.12[84]
13 CYP1A2 Cytochrome P450 1A2 [85] -8.12[86] -6.97[87] -8.54[88] -7.39[89] -6.65[90] -1.80[91]
14 HAAO 3-hydroxyanthranilate 3,4-dioxygenase [92] -0.71[93] 0.22[94] -2.69[95] -8.44[96] -9.25[97] -0.83[98]
15 MAOB Amine oxidase [flavin-containing] B [99] 0.43[100] -0.12[101] -0.37[102] 0.48[103] -6.08[104] -0.14[105]
16 ALDH9A1 4-trimethylaminobutyraldehyde dehydrogenase [106] -0.07[107] 0.56[108] 0.89[109] 1.14[110] 2.46[111] -0.11[112]
17 ALDH3A2 Fatty aldehyde dehydrogenase [113] 2.79[114] 2.55[115] 1.10[116] 1.98[117] 2.29[118] 0.27[119]
18 CYP1A1 Cytochrome P450 1A1 [120] -1.67[121] -3.40[122] -0.65[123] -2.79[124] -2.18[125] -5.94[126]
19 CYP2C18 Cytochrome P450 2C18 [127] -8.67[128] -10.30[129] -5.36[130] -10.65[131] -7.56[132] -0.60[133]
20 HADH Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial [134] 0.41[135] 1.11[136] -0.02[137] -0.20[138] 1.35[139] -0.03[140]
21 PRMT1 Protein arginine N-methyltransferase 1 [141] 3.04[142] 2.94[143] 2.50[144] 1.61[145] 2.90[146] -2.09[147]
22 GCDH Glutaryl-CoA dehydrogenase, mitochondrial [148] -0.30[149] 0.36[150] -0.01[151] -2.07[152] 0.25[153] -0.93[154]
23 ACMSD 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase [155] -11.13[156] -8.50[157] -2.59[158] -9.43[159] -7.83[160] -0.76[161]
24 AFMID Kynurenine formamidase [162] 2.14[163] 3.24[164] 0.65[165] -1.44[166] 0.26[167] 0.32[168]
25 CYP2J2 Cytochrome P450 2J2 [169] -2.61[170] -2.75[171] -0.54[172] -5.49[173] -2.86[174] 0.12[175]
26 DDC Aromatic-L-amino-acid decarboxylase [176] 0.72[177] 1.77[178] 2.27[179] -4.51[180] -4.39[181] 0.02[182]
27 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [183] 3.54[184] 2.78[185] 2.77[186] 3.73[187] 4.83[188] 1.14[189]
28 CYP4F12 Cytochrome P450 4F12 [190] 0.10[191] 1.28[192] 1.55[193] -2.25[194] -5.14[195] 0.05[196]
29 AADAT Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [197] 0.93[198] 1.01[199] -1.63[200] -0.33[201] 1.24[202] 0.08[203]
30 CYP1B1 Cytochrome P450 1B1 [204] -4.25[205] -3.83[206] -0.64[207] 4.20[208] 7.97[209] 0.87[210]
31 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [211] -5.23[212] -4.10[213] [214] -6.33[215] -1.45[216] 2.13[217]
32 CYP19A1 Aromatase [218] 4.73[219] 5.60[220] -1.76[221] 1.04[222] -0.25[223] -6.48[224]
33 ASMT Acetylserotonin O-methyltransferase [225] [226] [227] [228] [229] [230] [231]
34 IDO1 Indoleamine 2,3-dioxygenase 1 [232] 1.43[233] 2.08[234] 0.25[235] 4.43[236] 2.22[237] 0.22[238]
35 INMT Indolethylamine N-methyltransferase [239] 1.84[240] 2.42[241] 1.36[242] 3.86[243] 2.47[244] 6.67[245]
36 ALDH1A2 Retinal dehydrogenase 2 [246] -1.13[247] -1.20[248] 1.28[249] 1.90[250] 10.64[251] 2.06[252]
37 CYP2A13 Cytochrome P450 2A13 [253] [254] [255] [256] [257] [258] -0.66[259]
38 CYP2F1 Cytochrome P450 2F1 [260] 2.02[261] 0.25[262] 3.65[263] 4.13[264] 4.19[265] 0.83[266]
39 AANAT Serotonin N-acetyltransferase [267] 2.15[268] 4.54[269] 3.67[270] 4.06[271] 4.72[272] 0.99[273]
40 TPH1 Tryptophan 5-hydroxylase 1 [274] [275] [276] [277] [278] [279] [280]
41 AOC1 Amiloride-sensitive amine oxidase [copper-containing] [281] [282] [283] [284] [285] [286] [287]
42 WARS1 [288] [289] [290] [291] [292] [293] [294]
[1]
ref_hepatocyte CYP2E1
Mean 1.39e+03
Standard deviation 1.9e+03
Values 90 4.1e+03 2.7e+03 0 4.6
[2]
HepG2 CYP2E1
Mean 0.133
Standard deviation 0.1
Values 0.06 0.21
[3]
HepG2.C3A CYP2E1
Mean 0.107
Standard deviation 0.15
Values 0 0.21
[4]
HuH.7 CYP2E1
Mean 0.975
Standard deviation 0.29
Values 0.99 1.3 0.67
[5]
SNU475 CYP2E1
Mean 0.0289
Standard deviation 0.005
Values 0.025 0.032
[6]
THLE CYP2E1
Mean 0.0955
Standard deviation 0.082
Values 0.15 0.037
[7]
liver CYP2E1
Mean 1.49e+03
Standard deviation 8.2e+02
Values 6.9e+02 1e+03 2.6e+03 1.7e+03
[8]
ref_hepatocyte ALDH2
Mean 413
Standard deviation 5.9e+02
Values 22 1.4e+03 6.4e+02 20 27
[9]
HepG2 ALDH2
Mean 122
Standard deviation 2.9
Values 1.2e+02 1.2e+02
[10]
HepG2.C3A ALDH2
Mean 58.8
Standard deviation 8.6
Values 53 65
[11]
HuH.7 ALDH2
Mean 71
Standard deviation 19
Values 83 49 81
[12]
SNU475 ALDH2
Mean 34.9
Standard deviation 8.2
Values 29 41
[13]
THLE ALDH2
Mean 39.5
Standard deviation 1.8
Values 38 41
[14]
liver ALDH2
Mean 429
Standard deviation 2.9e+02
Values 1.8e+02 1.8e+02 7.1e+02 6.5e+02
[15]
ref_hepatocyte ALDH1A1
Mean 382
Standard deviation 2.7e+02
Values 20 4.3e+02 2.8e+02 4.1e+02 7.6e+02
[16]
HepG2 ALDH1A1
Mean 298
Standard deviation 51
Values 3.3e+02 2.6e+02
[17]
HepG2.C3A ALDH1A1
Mean 148
Standard deviation 48
Values 1.8e+02 1.1e+02
[18]
HuH.7 ALDH1A1
Mean 1.17e+03
Standard deviation 3.9e+02
Values 1.4e+03 7.1e+02 1.4e+03
[19]
SNU475 ALDH1A1
Mean 768
Standard deviation 3.3e+02
Values 5.4e+02 1e+03
[20]
THLE ALDH1A1
Mean 2.59
Standard deviation 1.5
Values 3.6 1.6
[21]
liver ALDH1A1
Mean 207
Standard deviation 1.4e+02
Values 68 2.8e+02 1.2e+02 3.6e+02
[22]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 11 9.6e+02 3.2e+02 0.24 11
[23]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.24 0.097
[24]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.2 0.068
[25]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.047 0.064 0.0082
[26]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[27]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[28]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 49 6.4e+02 4.3e+02 1.3e+03
[29]
ref_hepatocyte ECHS1
Mean 234
Standard deviation 2.7e+02
Values 36 6.2e+02 4.2e+02 50 41
[30]
HepG2 ECHS1
Mean 82.5
Standard deviation 19
Values 96 69
[31]
HepG2.C3A ECHS1
Mean 108
Standard deviation 1.4
Values 1.1e+02 1.1e+02
[32]
HuH.7 ECHS1
Mean 88.7
Standard deviation 28
Values 1.1e+02 59 93
[33]
SNU475 ECHS1
Mean 26.6
Standard deviation 2.9
Values 25 29
[34]
THLE ECHS1
Mean 34.4
Standard deviation 3
Values 32 37
[35]
liver ECHS1
Mean 293
Standard deviation 2.8e+02
Values 63 64 6.2e+02 4.2e+02
[36]
ref_hepatocyte ACAT1
Mean 166
Standard deviation 1.7e+02
Values 23 3.9e+02 3.2e+02 49 47
[37]
HepG2 ACAT1
Mean 65.7
Standard deviation 6.9
Values 71 61
[38]
HepG2.C3A ACAT1
Mean 53.7
Standard deviation 16
Values 65 43
[39]
HuH.7 ACAT1
Mean 22.9
Standard deviation 6
Values 29 17 22
[40]
SNU475 ACAT1
Mean 40.9
Standard deviation 14
Values 31 51
[41]
THLE ACAT1
Mean 21.3
Standard deviation 4.8
Values 18 25
[42]
liver ACAT1
Mean 353
Standard deviation 1.8e+02
Values 1.6e+02 2.4e+02 4.7e+02 5.4e+02
[43]
ref_hepatocyte AOX1
Mean 166
Standard deviation 2e+02
Values 25 4.8e+02 2.5e+02 12 68
[44]
HepG2 AOX1
Mean 28.7
Standard deviation 3.3
Values 31 26
[45]
HepG2.C3A AOX1
Mean 22.6
Standard deviation 2.4
Values 24 21
[46]
HuH.7 AOX1
Mean 0.258
Standard deviation 0.25
Values 0.066 0.55 0.16
[47]
SNU475 AOX1
Mean 7.67
Standard deviation 6.2
Values 12 3.3
[48]
THLE AOX1
Mean 26.7
Standard deviation 2.8
Values 29 25
[49]
liver AOX1
Mean 1.12e+03
Standard deviation 5.3e+02
Values 1.1e+03 1.8e+03 5.6e+02 9.6e+02
[50]
ref_hepatocyte DHCR24
Mean 160
Standard deviation 83
Values 44 2.6e+02 2e+02 1.8e+02 1.1e+02
[51]
HepG2 DHCR24
Mean 239
Standard deviation 90
Values 3e+02 1.8e+02
[52]
HepG2.C3A DHCR24
Mean 395
Standard deviation 1.3e+02
Values 3e+02 4.9e+02
[53]
HuH.7 DHCR24
Mean 482
Standard deviation 1.1e+02
Values 3.7e+02 5.9e+02 4.9e+02
[54]
SNU475 DHCR24
Mean 48.6
Standard deviation 27
Values 29 68
[55]
THLE DHCR24
Mean 93.2
Standard deviation 28
Values 73 1.1e+02
[56]
liver DHCR24
Mean 661
Standard deviation 1.8e+02
Values 5.3e+02 6.7e+02 5.4e+02 9.1e+02
[57]
ref_hepatocyte TDO2
Mean 130
Standard deviation 1.9e+02
Values 5.3 4.3e+02 2e+02 0 18
[58]
HepG2 TDO2
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[59]
HepG2.C3A TDO2
Mean 0.037
Standard deviation 0.039
Values 0.064 0.0097
[60]
HuH.7 TDO2
Mean 0.435
Standard deviation 0.39
Values 0.26 0.89 0.16
[61]
SNU475 TDO2
Mean 1.01
Standard deviation 0.68
Values 1.5 0.53
[62]
THLE TDO2
Mean 0.203
Standard deviation 0.19
Values 0.34 0.069
[63]
liver TDO2
Mean 397
Standard deviation 2.8e+02
Values 1.8e+02 1.8e+02 7.8e+02 4.4e+02
[64]
ref_hepatocyte CAT
Mean 121
Standard deviation 1.6e+02
Values 6.7 4e+02 1.4e+02 47 18
[65]
HepG2 CAT
Mean 64.4
Standard deviation 24
Values 81 48
[66]
HepG2.C3A CAT
Mean 46.5
Standard deviation 7.1
Values 51 41
[67]
HuH.7 CAT
Mean 62.9
Standard deviation 3.7
Values 64 59 66
[68]
SNU475 CAT
Mean 23.4
Standard deviation 1.8
Values 22 25
[69]
THLE CAT
Mean 17
Standard deviation 1.1
Values 16 18
[70]
liver CAT
Mean 242
Standard deviation 27
Values 2.5e+02 2e+02 2.6e+02 2.5e+02
[71]
ref_hepatocyte KYNU
Mean 90.5
Standard deviation 1.2e+02
Values 70 24 31 22 3.1e+02
[72]
HepG2 KYNU
Mean 27.4
Standard deviation 17
Values 16 39
[73]
HepG2.C3A KYNU
Mean 36.6
Standard deviation 14
Values 47 26
[74]
HuH.7 KYNU
Mean 4.72
Standard deviation 2.1
Values 3.2 7.1 3.9
[75]
SNU475 KYNU
Mean 8.24
Standard deviation 5.2
Values 12 4.6
[76]
THLE KYNU
Mean 5.29
Standard deviation 2.8
Values 7.2 3.3
[77]
liver KYNU
Mean 21.7
Standard deviation 3.4
Values 21 18 26 22
[78]
ref_hepatocyte HSD17B10
Mean 85.5
Standard deviation 74
Values 31 1.7e+02 1.7e+02 14 52
[79]
HepG2 HSD17B10
Mean 28.7
Standard deviation 2
Values 30 27
[80]
HepG2.C3A HSD17B10
Mean 21.3
Standard deviation 2.8
Values 23 19
[81]
HuH.7 HSD17B10
Mean 24.2
Standard deviation 9.3
Values 32 14 26
[82]
SNU475 HSD17B10
Mean 26.6
Standard deviation 1.5
Values 28 26
[83]
THLE HSD17B10
Mean 51.1
Standard deviation 6
Values 47 55
[84]
liver HSD17B10
Mean 61.9
Standard deviation 43
Values 24 25 95 1e+02
[85]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[86]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[87]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[88]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[89]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[90]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[91]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[92]
ref_hepatocyte HAAO
Mean 49.4
Standard deviation 65
Values 9.1 1.5e+02 72 8.2 3.8
[93]
HepG2 HAAO
Mean 9.61
Standard deviation 2.4
Values 11 7.9
[94]
HepG2.C3A HAAO
Mean 18
Standard deviation 2.2
Values 16 20
[95]
HuH.7 HAAO
Mean 4.33
Standard deviation 0.95
Values 4.9 3.2 4.8
[96]
SNU475 HAAO
Mean 0.0405
Standard deviation 0.021
Values 0.025 0.056
[97]
THLE HAAO
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[98]
liver HAAO
Mean 43.7
Standard deviation 25
Values 23 21 64 67
[99]
ref_hepatocyte MAOB
Mean 46.4
Standard deviation 48
Values 6.9 1.2e+02 70 20 15
[100]
HepG2 MAOB
Mean 19.9
Standard deviation 8.1
Values 26 14
[101]
HepG2.C3A MAOB
Mean 13.4
Standard deviation 5.7
Values 17 9.3
[102]
HuH.7 MAOB
Mean 20.3
Standard deviation 0.76
Values 19 21 21
[103]
SNU475 MAOB
Mean 18.4
Standard deviation 15
Values 7.7 29
[104]
THLE MAOB
Mean 0.0976
Standard deviation 0.012
Values 0.089 0.11
[105]
liver MAOB
Mean 66.2
Standard deviation 42
Values 26 35 1.1e+02 92
[106]
ref_hepatocyte ALDH9A1
Mean 45
Standard deviation 33
Values 14 94 53 14 49
[107]
HepG2 ALDH9A1
Mean 13.7
Standard deviation 4.1
Values 17 11
[108]
HepG2.C3A ALDH9A1
Mean 20.8
Standard deviation 1.7
Values 22 20
[109]
HuH.7 ALDH9A1
Mean 47.2
Standard deviation 5.8
Values 45 54 43
[110]
SNU475 ALDH9A1
Mean 28.2
Standard deviation 2.2
Values 27 30
[111]
THLE ALDH9A1
Mean 35.2
Standard deviation 4.8
Values 32 39
[112]
liver ALDH9A1
Mean 65.7
Standard deviation 27
Values 38 50 78 97
[113]
ref_hepatocyte ALDH3A2
Mean 44.1
Standard deviation 25
Values 7.1 76 44 41 52
[114]
HepG2 ALDH3A2
Mean 97
Standard deviation 12
Values 1.1e+02 89
[115]
HepG2.C3A ALDH3A2
Mean 80.8
Standard deviation 15
Values 91 70
[116]
HuH.7 ALDH3A2
Mean 53.4
Standard deviation 2.9
Values 50 55 55
[117]
SNU475 ALDH3A2
Mean 49.4
Standard deviation 7.9
Values 44 55
[118]
THLE ALDH3A2
Mean 30.6
Standard deviation 2.4
Values 29 32
[119]
liver ALDH3A2
Mean 83.6
Standard deviation 21
Values 55 88 85 1.1e+02
[120]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 0.06 82 17 77 43
[121]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 2.6 6.2
[122]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.2 1.4
[123]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 17 17 14
[124]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 3.1 0.49
[125]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[126]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.8 0.47 1.2 0.92
[127]
ref_hepatocyte CYP2C18
Mean 43
Standard deviation 35
Values 18 56 51 0 90
[128]
HepG2 CYP2C18
Mean 0.0336
Standard deviation 0.017
Values 0.021 0.046
[129]
HepG2.C3A CYP2C18
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[130]
HuH.7 CYP2C18
Mean 0.593
Standard deviation 0.1
Values 0.53 0.71 0.53
[131]
SNU475 CYP2C18
Mean 0.0076
Standard deviation 0.011
Values 0.015 0
[132]
THLE CYP2C18
Mean 0.0325
Standard deviation 0.029
Values 0.012 0.053
[133]
liver CYP2C18
Mean 44.5
Standard deviation 13
Values 31 57 36 54
[134]
ref_hepatocyte HADH
Mean 40.9
Standard deviation 39
Values 2.9 93 70 29 9.1
[135]
HepG2 HADH
Mean 17.3
Standard deviation 4.6
Values 21 14
[136]
HepG2.C3A HADH
Mean 27.7
Standard deviation 5.6
Values 32 24
[137]
HuH.7 HADH
Mean 22.8
Standard deviation 5.7
Values 28 17 23
[138]
SNU475 HADH
Mean 10.1
Standard deviation 2
Values 8.7 12
[139]
THLE HADH
Mean 14.8
Standard deviation 0.91
Values 14 15
[140]
liver HADH
Mean 62.8
Standard deviation 48
Values 15 29 1e+02 1e+02
[141]
ref_hepatocyte PRMT1
Mean 40.1
Standard deviation 17
Values 53 15 32 45 56
[142]
HepG2 PRMT1
Mean 105
Standard deviation 22
Values 90 1.2e+02
[143]
HepG2.C3A PRMT1
Mean 96.5
Standard deviation 1.5
Values 95 98
[144]
HuH.7 PRMT1
Mean 128
Standard deviation 40
Values 1.6e+02 83 1.4e+02
[145]
SNU475 PRMT1
Mean 34.9
Standard deviation 0.11
Values 35 35
[146]
THLE PRMT1
Mean 42.7
Standard deviation 5.5
Values 39 47
[147]
liver PRMT1
Mean 14.8
Standard deviation 4.4
Values 11 11 19 18
[148]
ref_hepatocyte GCDH
Mean 35.5
Standard deviation 31
Values 4.7 82 49 27 14
[149]
HepG2 GCDH
Mean 9.16
Standard deviation 0.58
Values 9.6 8.7
[150]
HepG2.C3A GCDH
Mean 14.3
Standard deviation 0.91
Values 14 15
[151]
HuH.7 GCDH
Mean 20
Standard deviation 9.2
Values 27 9.5 23
[152]
SNU475 GCDH
Mean 2.41
Standard deviation 0.62
Values 2 2.8
[153]
THLE GCDH
Mean 6.01
Standard deviation 1
Values 5.3 6.7
[154]
liver GCDH
Mean 29.4
Standard deviation 20
Values 16 11 56 34
[155]
ref_hepatocyte ACMSD
Mean 35.4
Standard deviation 47
Values 3 81 91 0 1.6
[156]
HepG2 ACMSD
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[157]
HepG2.C3A ACMSD
Mean 0.0307
Standard deviation 0.0021
Values 0.032 0.029
[158]
HuH.7 ACMSD
Mean 3.33
Standard deviation 0.47
Values 3.9 3.2 3
[159]
SNU475 ACMSD
Mean 0.0146
Standard deviation 0.00091
Values 0.015 0.014
[160]
THLE ACMSD
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[161]
liver ACMSD
Mean 32.8
Standard deviation 10
Values 19 32 35 44
[162]
ref_hepatocyte AFMID
Mean 27.8
Standard deviation 20
Values 4.8 35 51 41 7.6
[163]
HepG2 AFMID
Mean 39
Standard deviation 12
Values 47 31
[164]
HepG2.C3A AFMID
Mean 82.2
Standard deviation 14
Values 72 92
[165]
HuH.7 AFMID
Mean 24.5
Standard deviation 7.7
Values 32 17 25
[166]
SNU475 AFMID
Mean 2.9
Standard deviation 0.18
Values 2.8 3
[167]
THLE AFMID
Mean 4.73
Standard deviation 0.045
Values 4.7 4.8
[168]
liver AFMID
Mean 54.5
Standard deviation 41
Values 28 23 1.1e+02 54
[169]
ref_hepatocyte CYP2J2
Mean 23.2
Standard deviation 23
Values 9.9 51 44 1.9 9.2
[170]
HepG2 CYP2J2
Mean 1.21
Standard deviation 0.23
Values 1 1.4
[171]
HepG2.C3A CYP2J2
Mean 1.08
Standard deviation 0.51
Values 0.72 1.4
[172]
HuH.7 CYP2J2
Mean 8.98
Standard deviation 0.32
Values 9.3 9 8.6
[173]
SNU475 CYP2J2
Mean 0.147
Standard deviation 0.13
Values 0.24 0.056
[174]
THLE CYP2J2
Mean 0.454
Standard deviation 0.094
Values 0.52 0.39
[175]
liver CYP2J2
Mean 39.7
Standard deviation 21
Values 24 21 66 48
[176]
ref_hepatocyte DDC
Mean 16.2
Standard deviation 7.9
Values 3.1 24 19 20 15
[177]
HepG2 DDC
Mean 8.45
Standard deviation 3.2
Values 11 6.2
[178]
HepG2.C3A DDC
Mean 17.3
Standard deviation 4.6
Values 21 14
[179]
HuH.7 DDC
Mean 43.9
Standard deviation 9.4
Values 53 34 45
[180]
SNU475 DDC
Mean 0.201
Standard deviation 0.063
Values 0.16 0.25
[181]
THLE DDC
Mean 0.11
Standard deviation 0.087
Values 0.17 0.048
[182]
liver DDC
Mean 25.7
Standard deviation 11
Values 28 15 41 19
[183]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 12 7.8 11 6.1 11
[184]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 36 35
[185]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 19 23
[186]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 38 26 47
[187]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 31 42
[188]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[189]
liver OGDH
Mean 33.2
Standard deviation 11
Values 45 41 21 26
[190]
ref_hepatocyte CYP4F12
Mean 7.85
Standard deviation 7.8
Values 0.73 19 8.4 11 0.13
[191]
HepG2 CYP4F12
Mean 2.67
Standard deviation 0.39
Values 2.4 2.9
[192]
HepG2.C3A CYP4F12
Mean 5.98
Standard deviation 2.1
Values 4.5 7.5
[193]
HuH.7 CYP4F12
Mean 13
Standard deviation 3.4
Values 14 16 9.3
[194]
SNU475 CYP4F12
Mean 0.47
Standard deviation 0.47
Values 0.14 0.8
[195]
THLE CYP4F12
Mean 0.0316
Standard deviation 0.022
Values 0.047 0.016
[196]
liver CYP4F12
Mean 12.8
Standard deviation 14
Values 3.9 5.3 34 8.3
[197]
ref_hepatocyte AADAT
Mean 6.3
Standard deviation 9.1
Values 0.67 22 6.3 1.3 1.3
[198]
HepG2 AADAT
Mean 3.81
Standard deviation 2.5
Values 5.6 2
[199]
HepG2.C3A AADAT
Mean 3.96
Standard deviation 1.1
Values 4.7 3.2
[200]
HuH.7 AADAT
Mean 1.15
Standard deviation 0.46
Values 1.5 0.62 1.4
[201]
SNU475 AADAT
Mean 1.43
Standard deviation 0.11
Values 1.3 1.5
[202]
THLE AADAT
Mean 2.12
Standard deviation 0.11
Values 2 2.2
[203]
liver AADAT
Mean 10.5
Standard deviation 4.6
Values 6 7.2 16 13
[204]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.92 1.4 2.7 0.024 8
[205]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.03 0.057
[206]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.086 0.029
[207]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.95 1 0.87
[208]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 11 16
[209]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[210]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.2 7.4 6.9 9.5
[211]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 1.1 2.7 1.2 0 2.2
[212]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.013 0.011
[213]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.043 0.0097
[214]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[215]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[216]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[217]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 12 17 6.3 4.8
[218]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 0.28 0 0 5.3 0.08
[219]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 10 8.9
[220]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 13 21
[221]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.047 0.5 0.016
[222]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 1.1 0.25
[223]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[224]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0.079 0 0 0
[225]
ref_hepatocyte ASMT
Mean 0.657
Standard deviation 0.74
Values 0 0.88 1.8 0.29 0.27
[226]
HepG2 ASMT
Missing
[227]
HepG2.C3A ASMT
Missing
[228]
HuH.7 ASMT
Missing
[229]
SNU475 ASMT
Missing
[230]
THLE ASMT
Missing
[231]
liver ASMT
Missing
[232]
ref_hepatocyte IDO1
Mean 0.512
Standard deviation 0.3
Values 0.35 0.33 0.22 0.8 0.86
[233]
HepG2 IDO1
Mean 0.438
Standard deviation 0.012
Values 0.45 0.43
[234]
HepG2.C3A IDO1
Mean 0.68
Standard deviation 0.23
Values 0.51 0.85
[235]
HuH.7 IDO1
Mean 0.343
Standard deviation 0.071
Values 0.26 0.4 0.37
[236]
SNU475 IDO1
Mean 3.13
Standard deviation 1.9
Values 1.8 4.4
[237]
THLE IDO1
Mean 0.339
Standard deviation 0.014
Values 0.35 0.33
[238]
liver IDO1
Mean 0.937
Standard deviation 0.19
Values 1.1 1.1 0.85 0.72
[239]
ref_hepatocyte INMT
Mean 0.233
Standard deviation 0.17
Values 0.019 0.33 0.38 0.075 0.37
[240]
HepG2 INMT
Mean 0.265
Standard deviation 0.023
Values 0.25 0.28
[241]
HepG2.C3A INMT
Mean 0.391
Standard deviation 0.099
Values 0.46 0.32
[242]
HuH.7 INMT
Mean 0.338
Standard deviation 0.018
Values 0.33 0.36 0.33
[243]
SNU475 INMT
Mean 0.957
Standard deviation 0.36
Values 0.7 1.2
[244]
THLE INMT
Mean 0.184
Standard deviation 0.049
Values 0.22 0.15
[245]
liver INMT
Mean 37.2
Standard deviation 11
Values 37 23 50 38
[246]
ref_hepatocyte ALDH1A2
Mean 0.153
Standard deviation 0.15
Values 0.37 0.24 0.086 0 0.075
[247]
HepG2 ALDH1A2
Mean 0.0222
Standard deviation 0.025
Values 0.0043 0.04
[248]
HepG2.C3A ALDH1A2
Mean 0.0209
Standard deviation 0.016
Values 0.032 0.0097
[249]
HuH.7 ALDH1A2
Mean 0.211
Standard deviation 0.19
Values 0.11 0.43 0.09
[250]
SNU475 ALDH1A2
Mean 0.162
Standard deviation 0.0069
Values 0.16 0.17
[251]
THLE ALDH1A2
Mean 34.9
Standard deviation 6.3
Values 30 39
[252]
liver ALDH1A2
Mean 1
Standard deviation 0.59
Values 1.8 1.1 0.47 0.64
[253]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0.057 0.28 0 0
[254]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[255]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[257]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[258]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[259]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0.04 0.13 0 0.1
[260]
ref_hepatocyte CYP2F1
Mean 0.026
Standard deviation 0.058
Values 0 0.13 0 0 0
[261]
HepG2 CYP2F1
Mean 0.0336
Standard deviation 0.007
Values 0.039 0.029
[262]
HepG2.C3A CYP2F1
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[263]
HuH.7 CYP2F1
Mean 0.185
Standard deviation 0.058
Values 0.14 0.25 0.16
[264]
SNU475 CYP2F1
Mean 0.129
Standard deviation 0.047
Values 0.096 0.16
[265]
THLE CYP2F1
Mean 0.0674
Standard deviation 0.0051
Values 0.071 0.064
[266]
liver CYP2F1
Mean 0.0726
Standard deviation 0.035
Values 0.093 0.071 0.024 0.1
[267]
ref_hepatocyte AANAT
Mean 0.00813
Standard deviation 0.018
Values 0 0.041 0 0 0
[268]
HepG2 AANAT
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[269]
HepG2.C3A AANAT
Mean 0.0593
Standard deviation 0.054
Values 0.021 0.097
[270]
HuH.7 AANAT
Mean 0.0585
Standard deviation 0.03
Values 0.084 0.026 0.066
[271]
SNU475 AANAT
Mean 0.0386
Standard deviation 0.0044
Values 0.035 0.042
[272]
THLE AANAT
Mean 0.0305
Standard deviation 0.0096
Values 0.024 0.037
[273]
liver AANAT
Mean 0.0253
Standard deviation 0.021
Values 0.026 0 0.024 0.051
[274]
ref_hepatocyte TPH1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[275]
HepG2 TPH1
Mean 0.0701
Standard deviation 0.01
Values 0.077 0.063
[276]
HepG2.C3A TPH1
Mean 0.269
Standard deviation 0.11
Values 0.34 0.19
[277]
HuH.7 TPH1
Mean 0.0367
Standard deviation 0.025
Values 0.019 0.026 0.066
[278]
SNU475 TPH1
Mean 0.0361
Standard deviation 0.008
Values 0.03 0.042
[279]
THLE TPH1
Mean 0.0911
Standard deviation 0.039
Values 0.12 0.064
[280]
liver TPH1
Mean 0.0508
Standard deviation 0.037
Values 0.066 0.086 0 0.051
[281]
ref_hepatocyte AOC1
Missing
[282]
HepG2 AOC1
Missing
[283]
HepG2.C3A AOC1
Missing
[284]
HuH.7 AOC1
Missing
[285]
SNU475 AOC1
Missing
[286]
THLE AOC1
Missing
[287]
liver AOC1
Missing
[288]
ref_hepatocyte WARS1
Missing
[289]
HepG2 WARS1
Missing
[290]
HepG2.C3A WARS1
Missing
[291]
HuH.7 WARS1
Missing
[292]
SNU475 WARS1
Missing
[293]
THLE WARS1
Missing
[294]
liver WARS1
Missing