WP_TP53_NETWORK Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SUMO1 Small ubiquitin-related modifier 1 [1] -1.49[2] -1.26[3] -0.92[4] -0.41[5] -1.22[6] -0.69[7]
2 GADD45A Growth arrest and DNA damage-inducible protein GADD45 alpha [8] -2.36[9] -3.37[10] -2.47[11] -2.93[12] -1.95[13] -2.16[14]
3 CDKN1A Cyclin-dependent kinase inhibitor 1 [15] 0.95[16] -0.37[17] -2.36[18] -0.93[19] 0.87[20] -0.98[21]
4 MYC Myc proto-oncogene protein [22] 0.54[23] 0.27[24] -1.05[25] -1.73[26] -0.12[27] -1.14[28]
5 BAX Apoptosis regulator BAX [29] 0.44[30] -0.29[31] -0.04[32] -0.54[33] -0.92[34] -3.10[35]
6 BOK Bcl-2-related ovarian killer protein [36] -0.01[37] 0.48[38] -2.33[39] -0.84[40] -1.97[41] 1.16[42]
7 TNFSF10 Tumor necrosis factor ligand superfamily member 10 [43] -4.36[44] -2.69[45] 0.64[46] -1.41[47] -5.42[48] -0.54[49]
8 BID BH3-interacting domain death agonist [50] -0.16[51] 0.01[52] 0.34[53] 0.77[54] -0.53[55] 1.03[56]
9 MDM2 E3 ubiquitin-protein ligase Mdm2 [57] 2.22[58] 3.71[59] 1.65[60] 1.57[61] 1.69[62] 3.02[63]
10 TP53 Cellular tumor antigen p53 [64] 1.75[65] 1.38[66] 2.84[67] 2.35[68] 1.26[69] 0.81[70]
11 BBC3 Bcl-2-binding component 3 [71] 0.85[72] 0.80[73] 1.00[74] -1.74[75] -1.75[76] -3.48[77]
12 ABL1 Tyrosine-protein kinase ABL1 [78] 2.34[79] 1.80[80] 3.30[81] 3.13[82] 3.06[83] 1.79[84]
13 PMAIP1 Phorbol-12-myristate-13-acetate-induced protein 1 [85] 0.16[86] -3.14[87] 1.12[88] 3.34[89] 1.80[90] -3.44[91]
14 ATM Serine-protein kinase ATM [92] 3.14[93] 4.81[94] 5.24[95] 5.22[96] 3.94[97] 5.84[98]
15 CDKN2A Cyclin-dependent kinase inhibitor 2A [99] 4.19[100] 2.03[101] 6.14[102] 6.27[103] 7.29[104] -1.30[105]
16 TP73 Tumor protein p73 [106] 0.83[107] 3.46[108] 3.08[109] 1.74[110] 2.11[111] 1.50[112]
17 BCL2 Apoptosis regulator Bcl-2 [113] -2.74[114] 2.73[115] -3.97[116] 2.83[117] 1.79[118] 4.08[119]
18 TP63 Tumor protein 63 [120] [121] [122] -1.19[123] -0.31[124] -4.65[125] -0.63[126]
19 OTX2 Homeobox protein OTX2 [127] [128] [129] [130] -0.41[131] [132] [133]
20 MIR3191 [134] [135] [136] [137] [138] [139] [140]
[1]
ref_hepatocyte SUMO1
Mean 76.3
Standard deviation 10
Values 89 77 61 80 74
[2]
HepG2 SUMO1
Mean 55.7
Standard deviation 4.2
Values 59 53
[3]
HepG2.C3A SUMO1
Mean 55.2
Standard deviation 14
Values 65 45
[4]
HuH.7 SUMO1
Mean 41.2
Standard deviation 13
Values 53 27 44
[5]
SNU475 SUMO1
Mean 50.5
Standard deviation 16
Values 40 62
[6]
THLE SUMO1
Mean 54.6
Standard deviation 7.9
Values 49 60
[7]
liver SUMO1
Mean 37.2
Standard deviation 30
Values 10 13 71 54
[8]
ref_hepatocyte GADD45A
Mean 72.7
Standard deviation 61
Values 1.2e+02 36 23 28 1.5e+02
[9]
HepG2 GADD45A
Mean 29
Standard deviation 18
Values 16 42
[10]
HepG2.C3A GADD45A
Mean 12.2
Standard deviation 0.97
Values 12 13
[11]
HuH.7 GADD45A
Mean 13.4
Standard deviation 4.4
Values 13 18 9.2
[12]
SNU475 GADD45A
Mean 8.43
Standard deviation 3
Values 11 6.3
[13]
THLE GADD45A
Mean 31.4
Standard deviation 0.034
Values 31 31
[14]
liver GADD45A
Mean 12.8
Standard deviation 5.7
Values 11 5.8 15 19
[15]
ref_hepatocyte CDKN1A
Mean 40.1
Standard deviation 28
Values 76 5.7 52 19 48
[16]
HepG2 CDKN1A
Mean 158
Standard deviation 49
Values 1.2e+02 1.9e+02
[17]
HepG2.C3A CDKN1A
Mean 53.9
Standard deviation 3.9
Values 57 51
[18]
HuH.7 CDKN1A
Mean 8
Standard deviation 1.9
Values 7.3 10 6.5
[19]
SNU475 CDKN1A
Mean 18.6
Standard deviation 7.8
Values 24 13
[20]
THLE CDKN1A
Mean 122
Standard deviation 11
Values 1.3e+02 1.1e+02
[21]
liver CDKN1A
Mean 16
Standard deviation 8.1
Values 16 6.2 16 26
[22]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 89 1.4 23 15 20
[23]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 52 1.3e+02
[24]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 52 73
[25]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 14 18 13
[26]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 8.9 6.9
[27]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[28]
liver MYC
Mean 10.6
Standard deviation 6
Values 5.5 5.9 18 13
[29]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 34 11 27 30 21
[30]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 58 80
[31]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 33 38
[32]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 34 14 26
[33]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 16 14
[34]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[35]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 1.4 2.5 2.3 2.9
[36]
ref_hepatocyte BOK
Mean 22.1
Standard deviation 14
Values 14 41 32 16 7
[37]
HepG2 BOK
Mean 44.8
Standard deviation 8.4
Values 39 51
[38]
HepG2.C3A BOK
Mean 53.5
Standard deviation 23
Values 37 70
[39]
HuH.7 BOK
Mean 4.52
Standard deviation 0.61
Values 4.8 3.8 5
[40]
SNU475 BOK
Mean 10.9
Standard deviation 1.6
Values 9.8 12
[41]
THLE BOK
Mean 9.45
Standard deviation 0.048
Values 9.5 9.4
[42]
liver BOK
Mean 39
Standard deviation 23
Values 18 23 68 47
[43]
ref_hepatocyte TNFSF10
Mean 20
Standard deviation 23
Values 4.9 61 18 13 4.3
[44]
HepG2 TNFSF10
Mean 1.99
Standard deviation 0.0057
Values 2 2
[45]
HepG2.C3A TNFSF10
Mean 5.38
Standard deviation 0.9
Values 4.8 6
[46]
HuH.7 TNFSF10
Mean 31.9
Standard deviation 15
Values 26 49 21
[47]
SNU475 TNFSF10
Mean 6.62
Standard deviation 4.6
Values 3.4 9.9
[48]
THLE TNFSF10
Mean 0.781
Standard deviation 0.14
Values 0.88 0.68
[49]
liver TNFSF10
Mean 10.8
Standard deviation 3.9
Values 15 7 14 8
[50]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 17 12 15 4.5 12
[51]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 23 22
[52]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 25 18
[53]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 21 12 15
[54]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 17 19
[55]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[56]
liver BID
Mean 19.7
Standard deviation 11
Values 10 9.4 30 29
[57]
ref_hepatocyte MDM2
Mean 6.36
Standard deviation 2.9
Values 5 4.8 3.6 11 7.6
[58]
HepG2 MDM2
Mean 60.6
Standard deviation 13
Values 70 51
[59]
HepG2.C3A MDM2
Mean 145
Standard deviation 52
Values 1.8e+02 1.1e+02
[60]
HuH.7 MDM2
Mean 20.4
Standard deviation 0.31
Values 20 20 21
[61]
SNU475 MDM2
Mean 16.7
Standard deviation 1.8
Values 15 18
[62]
THLE MDM2
Mean 34.2
Standard deviation 0.86
Values 35 34
[63]
liver MDM2
Mean 40.5
Standard deviation 11
Values 45 54 29 35
[64]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 6.2 5.5 5.5 5.5 3.7
[65]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[66]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 25 23
[67]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 46 20 50
[68]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 19 28
[69]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[70]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 5.6 5 9 9.5
[71]
ref_hepatocyte BBC3
Mean 4.09
Standard deviation 4.3
Values 11 1.3 3.2 3.6 0.92
[72]
HepG2 BBC3
Mean 15.1
Standard deviation 11
Values 7 23
[73]
HepG2.C3A BBC3
Mean 12.4
Standard deviation 9.8
Values 5.5 19
[74]
HuH.7 BBC3
Mean 8.39
Standard deviation 3.1
Values 7.8 12 5.7
[75]
SNU475 BBC3
Mean 1.08
Standard deviation 0.44
Values 0.77 1.4
[76]
THLE BBC3
Mean 2.04
Standard deviation 0.082
Values 2.1 2
[77]
liver BBC3
Mean 0.288
Standard deviation 0.11
Values 0.44 0.3 0.24 0.18
[78]
ref_hepatocyte ABL1
Mean 3.99
Standard deviation 2.5
Values 8 2 1.7 4.1 4.1
[79]
HepG2 ABL1
Mean 41.3
Standard deviation 2.2
Values 40 43
[80]
HepG2.C3A ABL1
Mean 24.2
Standard deviation 1.3
Values 25 23
[81]
HuH.7 ABL1
Mean 40.3
Standard deviation 6.6
Values 35 38 48
[82]
SNU475 ABL1
Mean 30.8
Standard deviation 0.67
Values 30 31
[83]
THLE ABL1
Mean 55.5
Standard deviation 15
Values 45 66
[84]
liver ABL1
Mean 10.9
Standard deviation 3.5
Values 14 13 8.1 7.7
[85]
ref_hepatocyte PMAIP1
Mean 2.2
Standard deviation 2.9
Values 6.7 0.54 0.22 0.061 3.5
[86]
HepG2 PMAIP1
Mean 5.03
Standard deviation 2.9
Values 3 7.1
[87]
HepG2.C3A PMAIP1
Mean 0.435
Standard deviation 0.037
Values 0.46 0.41
[88]
HuH.7 PMAIP1
Mean 4.88
Standard deviation 0.84
Values 4.2 5.8 4.6
[89]
SNU475 PMAIP1
Mean 19.7
Standard deviation 2.1
Values 21 18
[90]
THLE PMAIP1
Mean 12.8
Standard deviation 1
Values 14 12
[91]
liver PMAIP1
Mean 0.159
Standard deviation 0.092
Values 0.053 0.11 0.21 0.26
[92]
ref_hepatocyte ATM
Mean 0.969
Standard deviation 0.7
Values 0.27 1.1 0.7 2.1 0.69
[93]
HepG2 ATM
Mean 17.5
Standard deviation 8.3
Values 23 12
[94]
HepG2.C3A ATM
Mean 47.4
Standard deviation 4.5
Values 51 44
[95]
HuH.7 ATM
Mean 37.5
Standard deviation 9.1
Values 27 44 41
[96]
SNU475 ATM
Mean 31.7
Standard deviation 8.2
Values 26 38
[97]
THLE ATM
Mean 24.9
Standard deviation 4.4
Values 28 22
[98]
liver ATM
Mean 43.7
Standard deviation 31
Values 64 76 17 17
[99]
ref_hepatocyte CDKN2A
Mean 0.323
Standard deviation 0.62
Values 0 0.065 0.13 1.4 0
[100]
HepG2 CDKN2A
Mean 12.1
Standard deviation 5.5
Values 8.2 16
[101]
HepG2.C3A CDKN2A
Mean 2.29
Standard deviation 0.19
Values 2.4 2.1
[102]
HuH.7 CDKN2A
Mean 23.3
Standard deviation 9
Values 32 14 24
[103]
SNU475 CDKN2A
Mean 21.9
Standard deviation 6.8
Values 17 27
[104]
THLE CDKN2A
Mean 84.5
Standard deviation 8.9
Values 78 91
[105]
liver CDKN2A
Mean 0.103
Standard deviation 0.079
Values 0.026 0.071 0.21 0.1
[106]
ref_hepatocyte TP73
Mean 0.183
Standard deviation 0.15
Values 0.19 0.098 0.23 0.4 0
[107]
HepG2 TP73
Mean 0.666
Standard deviation 0.13
Values 0.76 0.57
[108]
HepG2.C3A TP73
Mean 3.48
Standard deviation 0.49
Values 3.8 3.1
[109]
HuH.7 TP73
Mean 1.58
Standard deviation 0.41
Values 1.3 1.4 2.1
[110]
SNU475 TP73
Mean 0.537
Standard deviation 0.035
Values 0.51 0.56
[111]
THLE TP73
Mean 1.32
Standard deviation 0.075
Values 1.3 1.4
[112]
liver TP73
Mean 0.407
Standard deviation 0.19
Values 0.64 0.47 0.19 0.33
[113]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.15 0.2 0.12 0.019 0
[114]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.026 0.034
[115]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 0.99 1.3
[116]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[117]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.68 0.55
[118]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[119]
liver BCL2
Mean 1.31
Standard deviation 1
Values 2.5 1.8 0.49 0.49
[120]
ref_hepatocyte TP63
Mean 0.0845
Standard deviation 0.17
Values 0.4 0 0 0 0.026
[121]
HepG2 TP63
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A TP63
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 TP63
Mean 0.038
Standard deviation 0.033
Values 0.056 0.058 0
[124]
SNU475 TP63
Mean 0.06
Standard deviation 0.059
Values 0.1 0.019
[125]
THLE TP63
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[126]
liver TP63
Mean 0.0431
Standard deviation 0.045
Values 0.11 0.043 0.024 0
[127]
ref_hepatocyte OTX2
Mean 0.0407
Standard deviation 0.091
Values 0 0.2 0 0 0
[128]
HepG2 OTX2
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A OTX2
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 OTX2
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 OTX2
Mean 0.027
Standard deviation 0.012
Values 0.035 0.019
[132]
THLE OTX2
Mean 0
Standard deviation 0
Values 0 0
[133]
liver OTX2
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte MIR3191
Missing
[135]
HepG2 MIR3191
Missing
[136]
HepG2.C3A MIR3191
Missing
[137]
HuH.7 MIR3191
Missing
[138]
SNU475 MIR3191
Missing
[139]
THLE MIR3191
Missing
[140]
liver MIR3191
Missing