WP_TLR4_SIGNALING_AND_TOLERANCE | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | NFKBIA | NF-kappa-B inhibitor alpha | [1] | -0.97[2] | -2.83[3] | -2.90[4] | -4.05[5] | -1.67[6] | -1.19[7] |
2 | TRAM1 | Translocating chain-associated membrane protein 1 | [8] | -0.42[9] | 0.09[10] | 0.34[11] | 1.16[12] | -0.59[13] | 0.19[14] |
3 | IKBKG | NF-kappa-B essential modulator | [15] | -0.80[16] | -0.73[17] | -2.67[18] | -1.38[19] | -2.10[20] | -0.66[21] |
4 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | [22] | 1.50[23] | 0.82[24] | 0.11[25] | 0.26[26] | 1.13[27] | -0.74[28] |
5 | MYD88 | Myeloid differentiation primary response protein MyD88 | [29] | -0.10[30] | -0.12[31] | -0.37[32] | -1.57[33] | -0.77[34] | 0.74[35] |
6 | IRF7 | Interferon regulatory factor 7 | [36] | -9.14[37] | -8.22[38] | -6.81[39] | -3.68[40] | -3.44[41] | -0.13[42] |
7 | IRF3 | Interferon regulatory factor 3 | [43] | 0.39[44] | 0.48[45] | 1.52[46] | -0.18[47] | -0.09[48] | -1.24[49] |
8 | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 | [50] | 0.45[51] | 0.54[52] | 1.12[53] | 1.17[54] | 1.12[55] | 0.19[56] |
9 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [57] | -0.01[58] | 0.98[59] | 1.16[60] | -0.05[61] | 0.64[62] | 0.19[63] |
10 | TBK1 | Serine/threonine-protein kinase TBK1 | [64] | -0.55[65] | 1.06[66] | 0.51[67] | -0.04[68] | 0.54[69] | 0.42[70] |
11 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [71] | 0.76[72] | 0.36[73] | 0.46[74] | -0.78[75] | 0.63[76] | 0.40[77] |
12 | TICAM1 | TIR domain-containing adapter molecule 1 | [78] | -0.62[79] | -1.80[80] | -0.56[81] | -1.76[82] | -0.21[83] | -0.56[84] |
13 | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 | [85] | 0.38[86] | 0.46[87] | 0.45[88] | 0.54[89] | 0.57[90] | 1.43[91] |
14 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [92] | 0.99[93] | 2.14[94] | 2.41[95] | 0.12[96] | 1.43[97] | 1.46[98] |
15 | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | [99] | 0.74[100] | 1.31[101] | 1.69[102] | -0.53[103] | 0.31[104] | 0.17[105] |
16 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [106] | 0.61[107] | 0.59[108] | 1.01[109] | -0.28[110] | 0.32[111] | 1.13[112] |
17 | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein | [113] | -0.05[114] | -0.16[115] | 0.26[116] | -0.25[117] | -0.93[118] | 0.21[119] |
18 | IRAK4 | Interleukin-1 receptor-associated kinase 4 | [120] | 0.35[121] | 1.63[122] | 2.22[123] | 0.88[124] | 1.14[125] | 1.72[126] |
19 | IL6 | Interleukin-6 | [127] | -8.35[128] | [129] | -4.51[130] | -1.39[131] | 1.62[132] | [133] |
20 | TRAF3 | TNF receptor-associated factor 3 | [134] | 2.98[135] | 2.32[136] | 2.24[137] | 2.29[138] | 3.21[139] | 1.87[140] |
21 | INPP5D | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 | [141] | 3.94[142] | 4.25[143] | -5.63[144] | -6.20[145] | -2.75[146] | 1.22[147] |
22 | TRAF6 | TNF receptor-associated factor 6 | [148] | 1.18[149] | 0.99[150] | 1.87[151] | 1.13[152] | 1.08[153] | 2.85[154] |
23 | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon | [155] | 1.81[156] | 1.60[157] | 0.81[158] | 2.03[159] | 2.08[160] | -0.29[161] |
24 | TLR4 | Toll-like receptor 4 | [162] | 0.36[163] | -4.87[164] | -5.45[165] | -5.63[166] | 5.29[167] | 4.41[168] |
25 | TNF | Tumor necrosis factor | [169] | 1.19[170] | -1.02[171] | -5.31[172] | -2.76[173] | -5.48[174] | -1.95[175] |
26 | IRAK3 | Interleukin-1 receptor-associated kinase 3 | [176] | -1.36[177] | -0.45[178] | 1.73[179] | 5.51[180] | 8.25[181] | 5.83[182] |
27 | MIR6502 | [183] | [184] | [185] | [186] | [187] | [188] | [189] | |
28 | CXCL8 | Interleukin-8 | [190] | [191] | [192] | [193] | [194] | [195] | [196] |
29 | MIR718 | [197] | [198] | [199] | [200] | [201] | [202] | [203] | |
30 | IFNB1 | Interferon beta | [204] | [205] | [206] | [207] | [208] | [209] | [210] |