WP_THYMIC_STROMAL_LYMPHOPOIETIN_TSLP_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | RPS6 | 40S ribosomal protein S6 | [1] | [2] | [3] | [4] | [5] | [6] | [7] |
2 | NFKBIA | NF-kappa-B inhibitor alpha | [8] | 0.20[9] | -1.49[10] | -1.79[11] | -2.35[12] | -0.41[13] | -0.14[14] |
3 | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1 | [15] | 0.26[16] | 0.05[17] | 0.73[18] | -2.13[19] | -0.52[20] | -0.60[21] |
4 | AKT1 | RAC-alpha serine/threonine-protein kinase | [22] | 1.33[23] | 1.21[24] | 0.20[25] | 1.12[26] | 1.20[27] | 0.76[28] |
5 | STAT3 | Signal transducer and activator of transcription 3 | [29] | 1.80[30] | 0.41[31] | 1.22[32] | 1.41[33] | 0.74[34] | 3.41[35] |
6 | MYC | Myc proto-oncogene protein | [36] | 1.68[37] | 1.45[38] | -0.50[39] | -1.62[40] | 0.81[41] | -1.00[42] |
7 | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1 | [43] | 0.32[44] | 0.10[45] | 0.75[46] | 0.63[47] | 1.19[48] | -0.19[49] |
8 | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 | [50] | 1.31[51] | 1.09[52] | 2.03[53] | 0.33[54] | 0.87[55] | -0.70[56] |
9 | PTPN11 | Tyrosine-protein phosphatase non-receptor type 11 | [57] | 1.70[58] | 2.24[59] | 2.26[60] | 2.06[61] | 2.75[62] | 2.26[63] |
10 | YES1 | Tyrosine-protein kinase Yes | [64] | 0.39[65] | 1.99[66] | 2.28[67] | 1.62[68] | 1.14[69] | 1.12[70] |
11 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [71] | 1.18[72] | 0.37[73] | 1.55[74] | 3.70[75] | 1.49[76] | 1.95[77] |
12 | NFKB2 | Nuclear factor NF-kappa-B p100 subunit | [78] | 0.48[79] | 0.89[80] | 1.41[81] | -0.21[82] | 0.70[83] | -2.02[84] |
13 | RELA | Transcription factor p65 | [85] | 1.38[86] | 0.99[87] | 1.20[88] | 1.11[89] | 1.08[90] | 0.12[91] |
14 | STAT6 | Signal transducer and activator of transcription 6 | [92] | 1.60[93] | 1.95[94] | 0.94[95] | 2.02[96] | 1.97[97] | 1.70[98] |
15 | JAK1 | Tyrosine-protein kinase JAK1 | [99] | 1.76[100] | 1.36[101] | 1.61[102] | 1.80[103] | 2.50[104] | 2.53[105] |
16 | MAPK1 | Mitogen-activated protein kinase 1 | [106] | 2.96[107] | 3.21[108] | 3.11[109] | 3.02[110] | 2.72[111] | 2.78[112] |
17 | MAPK14 | Mitogen-activated protein kinase 14 | [113] | 2.73[114] | 2.90[115] | 2.55[116] | 2.85[117] | 2.38[118] | 2.28[119] |
18 | MAPK8 | Mitogen-activated protein kinase 8 | [120] | -0.19[121] | 1.33[122] | 0.27[123] | 0.27[124] | 0.18[125] | 0.49[126] |
19 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [127] | 1.92[128] | 1.71[129] | 1.57[130] | 0.92[131] | 1.89[132] | 1.45[133] |
20 | LYN | Tyrosine-protein kinase Lyn | [134] | 0.39[135] | 0.32[136] | 0.92[137] | 2.23[138] | 1.04[139] | 1.02[140] |
21 | CISH | Cytokine-inducible SH2-containing protein | [141] | -1.65[142] | -1.36[143] | -1.08[144] | -1.48[145] | -2.86[146] | 2.10[147] |
22 | MAPK9 | Mitogen-activated protein kinase 9 | [148] | 2.48[149] | 2.81[150] | 2.95[151] | 2.88[152] | 2.40[153] | 1.51[154] |
23 | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | [155] | 2.31[156] | 2.70[157] | 2.37[158] | 2.07[159] | 3.13[160] | 1.65[161] |
24 | MAPK3 | Mitogen-activated protein kinase 3 | [162] | 3.10[163] | 3.26[164] | 3.37[165] | 1.59[166] | 1.67[167] | -0.04[168] |
25 | RELB | Transcription factor RelB | [169] | 0.96[170] | 0.65[171] | 0.97[172] | 0.15[173] | 1.44[174] | -1.51[175] |
26 | STAT5B | Signal transducer and activator of transcription 5B | [176] | 2.61[177] | 2.34[178] | 3.12[179] | 2.72[180] | 1.92[181] | 2.62[182] |
27 | TSLP | Thymic stromal lymphopoietin | [183] | -7.18[184] | [185] | -8.24[186] | -4.66[187] | -1.43[188] | -1.68[189] |
28 | SRC | Proto-oncogene tyrosine-protein kinase Src | [190] | 4.28[191] | 4.37[192] | 3.44[193] | 3.57[194] | 2.80[195] | 0.15[196] |
29 | FES | Tyrosine-protein kinase Fes/Fps | [197] | 2.03[198] | 0.14[199] | 0.57[200] | -5.44[201] | -1.10[202] | 2.18[203] |
30 | MTOR | Serine/threonine-protein kinase mTOR | [204] | 3.78[205] | 4.91[206] | 4.55[207] | 3.85[208] | 3.99[209] | 4.45[210] |
31 | STAT5A | Signal transducer and activator of transcription 5A | [211] | -0.70[212] | 0.59[213] | -0.27[214] | 0.32[215] | 1.14[216] | 1.24[217] |
32 | FYN | Tyrosine-protein kinase Fyn | [218] | 2.19[219] | -6.30[220] | 2.34[221] | 2.64[222] | 4.22[223] | 1.97[224] |
33 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 0.87[225] | 2.62[226] | 2.88[227] | 2.30[228] | 2.56[229] | 2.91[230] | |
34 | GAB2 | GRB2-associated-binding protein 2 | [231] | 2.82[232] | 2.71[233] | 3.03[234] | 2.09[235] | 2.24[236] | 1.54[237] |
35 | HCK | Tyrosine-protein kinase HCK | [238] | -4.59[239] | -4.67[240] | [241] | -4.10[242] | -4.98[243] | 1.71[244] |
36 | IL6 | Interleukin-6 | [245] | -7.19[246] | [247] | -3.40[248] | 0.31[249] | 2.89[250] | [251] |
37 | STAT4 | Signal transducer and activator of transcription 4 | [252] | -3.59[253] | -2.41[254] | -1.81[255] | 2.80[256] | 1.67[257] | 2.03[258] |
38 | JAK2 | Tyrosine-protein kinase JAK2 | [259] | 1.48[260] | 1.58[261] | 1.21[262] | 1.93[263] | 2.59[264] | 3.71[265] |
39 | TEC | Tyrosine-protein kinase Tec | [266] | -0.90[267] | -1.19[268] | -0.53[269] | 2.51[270] | 0.99[271] | 2.59[272] |
40 | IL7R | Interleukin-7 receptor subunit alpha | [273] | -2.98[274] | -3.47[275] | -3.49[276] | 6.41[277] | 6.38[278] | 3.21[279] |
41 | LCK | Tyrosine-protein kinase Lck | [280] | 4.03[281] | 4.22[282] | -5.71[283] | -3.91[284] | -4.06[285] | 2.23[286] |
42 | BTK | Tyrosine-protein kinase BTK | [287] | -6.13[288] | [289] | 0.89[290] | -1.84[291] | -4.01[292] | 2.83[293] |
43 | IL2RA | Interleukin-2 receptor subunit alpha | [294] | [295] | -4.23[296] | [297] | -3.43[298] | -5.29[299] | 1.53[300] |
44 | TNFSF4 | Tumor necrosis factor ligand superfamily member 4 | [301] | 4.99[302] | 7.96[303] | 6.83[304] | 3.53[305] | 6.97[306] | 2.78[307] |
45 | CXCL8 | Interleukin-8 | [308] | [309] | [310] | [311] | [312] | [313] | [314] |
46 | CCL11 | Eotaxin | [315] | [316] | [317] | [318] | [319] | [320] | [321] |
47 | CRLF2 | Cytokine receptor-like factor 2 | [322] | [323] | [324] | [325] | [326] | [327] | [328] |