WP_THIAMINE_METABOLIC_PATHWAYS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TKT Transketolase [1] 0.19[2] 0.29[3] -0.51[4] 0.55[5] 0.06[6] -1.72[7]
2 PDHA1 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial -0.65[8] -0.83[9] -0.43[10] -0.92[11] -0.55[12] 0.57[13]
3 BCKDHA 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial [14] -1.68[15] -1.52[16] -0.81[17] -2.28[18] -1.31[19] 0.83[20]
4 BCKDK [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 0.77[21] 0.04[22] -0.41[23] -1.25[24] 0.04[25] 0.78[26]
5 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [27] 0.88[28] 0.09[29] 0.38[30] 0.66[31] 1.42[32] 1.71[33]
6 SLC19A2 Thiamine transporter 1 [34] -0.83[35] 0.87[36] -0.04[37] -1.74[38] 0.44[39] 0.00[40]
7 SLC19A3 Thiamine transporter 2 [41] -0.93[42] -4.45[43] 3.86[44] -2.80[45] -1.15[46] 0.82[47]
8 SLC25A19 Mitochondrial thiamine pyrophosphate carrier [48] 0.56[49] 0.57[50] -1.29[51] -1.88[52] -0.44[53] -1.37[54]
9 TPK1 Thiamin pyrophosphokinase 1 [55] -2.94[56] -4.24[57] -1.50[58] 0.44[59] 0.18[60] 1.01[61]
[1]
ref_hepatocyte TKT
Mean 86.7
Standard deviation 36
Values 1.2e+02 31 1.1e+02 74 92
[2]
HepG2 TKT
Mean 199
Standard deviation 1.1e+02
Values 1.2e+02 2.8e+02
[3]
HepG2.C3A TKT
Mean 213
Standard deviation 92
Values 1.5e+02 2.8e+02
[4]
HuH.7 TKT
Mean 181
Standard deviation 32
Values 1.5e+02 2.2e+02 1.8e+02
[5]
SNU475 TKT
Mean 303
Standard deviation 1e+02
Values 2.3e+02 3.7e+02
[6]
THLE TKT
Mean 136
Standard deviation 17
Values 1.2e+02 1.5e+02
[7]
liver TKT
Mean 27.9
Standard deviation 9
Values 28 36 15 32
[8]
ref_hepatocyte PDHA1
Mean 24.9
Standard deviation 8.4
Values 16 20 25 25 38
[9]
HepG2 PDHA1
Mean 32
Standard deviation 3.7
Values 35 29
[10]
HepG2.C3A PDHA1
Mean 28.2
Standard deviation 0.42
Values 28 28
[11]
HuH.7 PDHA1
Mean 55
Standard deviation 18
Values 67 34 64
[12]
SNU475 PDHA1
Mean 31.4
Standard deviation 0.34
Values 31 32
[13]
THLE PDHA1
Mean 25.6
Standard deviation 3
Values 24 28
[14]
liver PDHA1
Mean 39.1
Standard deviation 23
Values 17 22 54 63
[15]
ref_hepatocyte BCKDHA
Mean 21.2
Standard deviation 23
Values 7 43 48 2.1 5.2
[16]
HepG2 BCKDHA
Mean 13.3
Standard deviation 4.2
Values 10 16
[17]
HepG2.C3A BCKDHA
Mean 15
Standard deviation 6.3
Values 10 19
[18]
HuH.7 BCKDHA
Mean 35.9
Standard deviation 11
Values 42 24 42
[19]
SNU475 BCKDHA
Mean 10.4
Standard deviation 2.4
Values 8.7 12
[20]
THLE BCKDHA
Mean 12.9
Standard deviation 0.022
Values 13 13
[21]
liver BCKDHA
Mean 39.9
Standard deviation 28
Values 14 18 56 71
[22]
ref_hepatocyte BCKDK
Mean 11.9
Standard deviation 7.4
Values 13 16 21 5.4 3.5
[23]
HepG2 BCKDK
Mean 40.9
Standard deviation 5.4
Values 37 45
[24]
HepG2.C3A BCKDK
Mean 24.7
Standard deviation 3.8
Values 22 27
[25]
HuH.7 BCKDK
Mean 26.6
Standard deviation 7.3
Values 30 18 32
[26]
SNU475 BCKDK
Mean 11.9
Standard deviation 0.64
Values 11 12
[27]
THLE BCKDK
Mean 18.5
Standard deviation 3.5
Values 16 21
[28]
liver BCKDK
Mean 21.6
Standard deviation 15
Values 11 6.6 35 34
[29]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 12 7.8 11 6.1 11
[30]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 36 35
[31]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 19 23
[32]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 38 26 47
[33]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 31 42
[34]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[35]
liver OGDH
Mean 33.2
Standard deviation 11
Values 45 41 21 26
[36]
ref_hepatocyte SLC19A2
Mean 8.62
Standard deviation 6.1
Values 8.3 4.7 2.9 19 8.7
[37]
HepG2 SLC19A2
Mean 9.74
Standard deviation 1.7
Values 11 8.6
[38]
HepG2.C3A SLC19A2
Mean 31.9
Standard deviation 4.8
Values 28 35
[39]
HuH.7 SLC19A2
Mean 25
Standard deviation 1.1
Values 25 26 24
[40]
SNU475 SLC19A2
Mean 6.15
Standard deviation 0.42
Values 6.5 5.9
[41]
THLE SLC19A2
Mean 17.7
Standard deviation 0.8
Values 18 17
[42]
liver SLC19A2
Mean 9.14
Standard deviation 3.7
Values 13 11 8 4.7
[43]
ref_hepatocyte SLC19A3
Mean 3.24
Standard deviation 3.1
Values 0.62 7.7 5.2 0.9 1.7
[44]
HepG2 SLC19A3
Mean 3.42
Standard deviation 2.1
Values 1.9 4.9
[45]
HepG2.C3A SLC19A3
Mean 0.299
Standard deviation 0.059
Values 0.26 0.34
[46]
HuH.7 SLC19A3
Mean 139
Standard deviation 1.6
Values 1.4e+02 1.4e+02 1.4e+02
[47]
SNU475 SLC19A3
Mean 1.11
Standard deviation 0.1
Values 1.2 1
[48]
THLE SLC19A3
Mean 2.2
Standard deviation 0.79
Values 2.8 1.6
[49]
liver SLC19A3
Mean 6.07
Standard deviation 1.5
Values 6.8 7.7 4.3 5.5
[50]
ref_hepatocyte SLC25A19
Mean 2.66
Standard deviation 1.4
Values 3.7 1 2.8 4.2 1.6
[51]
HepG2 SLC25A19
Mean 7.91
Standard deviation 0.2
Values 7.8 8
[52]
HepG2.C3A SLC25A19
Mean 7.99
Standard deviation 3.3
Values 10 5.6
[53]
HuH.7 SLC25A19
Mean 3.24
Standard deviation 1.6
Values 4.6 1.4 3.7
[54]
SNU475 SLC25A19
Mean 1.73
Standard deviation 0.24
Values 1.9 1.6
[55]
THLE SLC25A19
Mean 2.96
Standard deviation 0.11
Values 2.9 3
[56]
liver SLC25A19
Mean 1.09
Standard deviation 0.4
Values 0.69 0.81 1.4 1.5
[57]
ref_hepatocyte TPK1
Mean 0.847
Standard deviation 0.66
Values 0.41 0.91 1.2 0 1.7
[58]
HepG2 TPK1
Mean 0.222
Standard deviation 0.035
Values 0.2 0.25
[59]
HepG2.C3A TPK1
Mean 0.0905
Standard deviation 0.037
Values 0.064 0.12
[60]
HuH.7 TPK1
Mean 0.891
Standard deviation 0.19
Values 1 0.97 0.67
[61]
SNU475 TPK1
Mean 2.75
Standard deviation 0.75
Values 2.2 3.3
[62]
THLE TPK1
Mean 1.45
Standard deviation 0.062
Values 1.5 1.4
[63]
liver TPK1
Mean 1.81
Standard deviation 0.36
Values 1.6 1.8 1.5 2.3