WP_TGIF_DISRUPTION_OF_SHH_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TGIF1 Homeobox protein TGIF1 [1] -0.88[2] -1.58[3] -0.74[4] -1.19[5] -0.99[6] -1.78[7]
2 TGIF2 Homeobox protein TGIF2 [8] 0.66[9] 1.04[10] 0.42[11] -3.08[12] -1.09[13] -0.82[14]
3 SMAD2 Mothers against decapentaplegic homolog 2 [15] 1.44[16] 1.65[17] 1.15[18] 1.58[19] 2.33[20] 2.64[21]
4 SHH Sonic hedgehog protein [22] -0.19[23] -0.40[24] -0.32[25] -7.98[26] -7.57[27] 0.20[28]
5 FGF8 Fibroblast growth factor 8 [29] -3.90[30] -3.62[31] 0.88[32] -2.72[33] [34] 2.77[35]
6 GLI3 Transcriptional activator GLI3 [36] -1.80[37] [38] -0.90[39] 8.13[40] 7.06[41] 4.23[42]
7 NODAL Nodal homolog [43] 3.32[44] -0.45[45] 4.37[46] 2.76[47] 2.03[48] 4.75[49]
8 NKX2-1 Homeobox protein Nkx-2.1 [50] [51] [52] [53] [54] [55] [56]
9 FOXG1 Forkhead box protein G1 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte TGIF1
Mean 16.4
Standard deviation 7.1
Values 23 6.4 12 18 22
[2]
HepG2 TGIF1
Mean 29.4
Standard deviation 8.9
Values 23 36
[3]
HepG2.C3A TGIF1
Mean 16.8
Standard deviation 4.7
Values 13 20
[4]
HuH.7 TGIF1
Mean 28.6
Standard deviation 4.6
Values 28 34 25
[5]
SNU475 TGIF1
Mean 23.1
Standard deviation 0.016
Values 23 23
[6]
THLE TGIF1
Mean 20.1
Standard deviation 0.36
Values 20 20
[7]
liver TGIF1
Mean 6.47
Standard deviation 2.5
Values 4.2 4.4 8.7 8.6
[8]
ref_hepatocyte TGIF2
Mean 5.52
Standard deviation 6.3
Values 2.3 1.2 2.1 16 5.5
[9]
HepG2 TGIF2
Mean 28.8
Standard deviation 4.1
Values 26 32
[10]
HepG2.C3A TGIF2
Mean 34.7
Standard deviation 11
Values 27 42
[11]
HuH.7 TGIF2
Mean 21.6
Standard deviation 5.1
Values 26 16 23
[12]
SNU475 TGIF2
Mean 2.09
Standard deviation 0.75
Values 1.6 2.6
[13]
THLE TGIF2
Mean 6.33
Standard deviation 0.15
Values 6.2 6.4
[14]
liver TGIF2
Mean 4.24
Standard deviation 1.8
Values 3 2.5 5.1 6.4
[15]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 1.9 1.6 1.9 4.5 2.8
[16]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 24 21
[17]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 23 25
[18]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 15 18 17
[19]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 22 27
[20]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[21]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 25 29 17 15
[22]
ref_hepatocyte SHH
Mean 1.15
Standard deviation 1
Values 2.5 1.6 1.4 0.23 0
[23]
HepG2 SHH
Mean 3.31
Standard deviation 2.1
Values 1.8 4.8
[24]
HepG2.C3A SHH
Mean 2.66
Standard deviation 0.92
Values 2 3.3
[25]
HuH.7 SHH
Mean 2.69
Standard deviation 0.5
Values 2.3 3.3 2.5
[26]
SNU475 SHH
Mean 0.0146
Standard deviation 0.00091
Values 0.015 0.014
[27]
THLE SHH
Mean 0.0148
Standard deviation 0.021
Values 0.03 0
[28]
liver SHH
Mean 1.79
Standard deviation 2.1
Values 4.1 2.9 0.12 0
[29]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0.098 0 0 0
[30]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0.0086 0
[31]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[32]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.075 0.051 0.19
[33]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.0051 0.014
[34]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[35]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.25 0.34 0.047 0.077
[36]
ref_hepatocyte GLI3
Mean 0.0152
Standard deviation 0.021
Values 0.043 0.033 0 0 0
[37]
HepG2 GLI3
Mean 0.0143
Standard deviation 0.02
Values 0 0.029
[38]
HepG2.C3A GLI3
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 GLI3
Mean 0.0238
Standard deviation 0.021
Values 0 0.039 0.033
[40]
SNU475 GLI3
Mean 13.7
Standard deviation 1.2
Values 13 14
[41]
THLE GLI3
Mean 4.94
Standard deviation 1.2
Values 4.1 5.8
[42]
liver GLI3
Mean 0.384
Standard deviation 0.18
Values 0.42 0.37 0.59 0.15
[43]
ref_hepatocyte NODAL
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[44]
HepG2 NODAL
Mean 0.214
Standard deviation 0.03
Values 0.19 0.23
[45]
HepG2.C3A NODAL
Mean 0.0146
Standard deviation 0.021
Values 0 0.029
[46]
HuH.7 NODAL
Mean 0.391
Standard deviation 0.15
Values 0.22 0.51 0.43
[47]
SNU475 NODAL
Mean 0.141
Standard deviation 0.029
Values 0.16 0.12
[48]
THLE NODAL
Mean 0.0648
Standard deviation 0.0088
Values 0.071 0.059
[49]
liver NODAL
Mean 0.236
Standard deviation 0.26
Values 0.58 0.29 0.024 0.051
[50]
ref_hepatocyte NKX2-1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 NKX2-1
Mean 0
Standard deviation 0
Values 0 0
[52]
HepG2.C3A NKX2-1
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 NKX2-1
Mean 0
Standard deviation 0
Values 0 0 0
[54]
SNU475 NKX2-1
Mean 0.0164
Standard deviation 0.016
Values 0.0051 0.028
[55]
THLE NKX2-1
Mean 0
Standard deviation 0
Values 0 0
[56]
liver NKX2-1
Mean 0.0104
Standard deviation 0.014
Values 0.013 0.029 0 0
[57]
ref_hepatocyte FOXG1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 FOXG1
Mean 0.0122
Standard deviation 0.001
Values 0.013 0.011
[59]
HepG2.C3A FOXG1
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[60]
HuH.7 FOXG1
Mean 5.07
Standard deviation 0.98
Values 6.2 4.7 4.4
[61]
SNU475 FOXG1
Mean 18.8
Standard deviation 1.9
Values 17 20
[62]
THLE FOXG1
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[63]
liver FOXG1
Mean 0
Standard deviation 0
Values 0 0 0 0