WP_TGFBETA_RECEPTOR_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SERPINE1 | Plasminogen activator inhibitor 1 | [1] | -0.06[2] | 0.60[3] | -5.37[4] | -4.43[5] | 1.40[6] | -4.26[7] |
2 | FKBP1A | Peptidyl-prolyl cis-trans isomerase FKBP1A | [8] | -1.30[9] | -1.28[10] | -2.07[11] | -0.88[12] | -2.15[13] | -1.76[14] |
3 | JUN | Transcription factor AP-1 | [15] | -1.68[16] | -2.79[17] | -1.75[18] | -2.33[19] | -2.60[20] | -2.19[21] |
4 | FOS | Proto-oncogene c-Fos | [22] | -7.20[23] | -5.51[24] | -5.40[25] | -6.79[26] | -6.57[27] | -1.69[28] |
5 | CTNNB1 | Catenin beta-1 | [29] | 0.43[30] | 0.35[31] | 2.02[32] | 0.13[33] | -0.49[34] | 0.72[35] |
6 | STAT3 | Signal transducer and activator of transcription 3 | [36] | -0.64[37] | -1.71[38] | -0.20[39] | -0.38[40] | -1.95[41] | 2.02[42] |
7 | SPP1 | Osteopontin | [43] | 1.99[44] | 1.18[45] | -6.54[46] | 1.27[47] | -7.64[48] | -1.46[49] |
8 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [50] | -1.26[51] | -1.75[52] | 0.13[53] | 1.91[54] | -1.21[55] | 0.57[56] |
9 | TGIF1 | Homeobox protein TGIF1 | [57] | -1.49[58] | -1.70[59] | -0.10[60] | -1.01[61] | -2.22[62] | -2.24[63] |
10 | JAK1 | Tyrosine-protein kinase JAK1 | [64] | -0.68[65] | -0.76[66] | 0.19[67] | 0.00[68] | -0.20[69] | 1.15[70] |
11 | HRAS | GTPase HRas | [71] | -2.20[72] | -2.47[73] | -2.49[74] | -1.57[75] | -2.63[76] | -3.05[77] |
12 | TGFBR2 | TGF-beta receptor type-2 | [78] | 1.63[79] | 1.53[80] | 1.95[81] | 0.44[82] | 1.31[83] | 1.12[84] |
13 | THBS1 | Thrombospondin-1 | [85] | 1.31[86] | -3.09[87] | -2.31[88] | 2.22[89] | 1.06[90] | 0.73[91] |
14 | TFE3 | Transcription factor E3 | [92] | -0.53[93] | -0.76[94] | 0.52[95] | 0.81[96] | -1.07[97] | -0.48[98] |
15 | BAMBI | BMP and activin membrane-bound inhibitor homolog | [99] | 0.03[100] | -0.59[101] | 0.86[102] | 0.38[103] | -1.18[104] | -2.04[105] |
16 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [106] | -0.52[107] | -0.41[108] | 0.15[109] | -0.87[110] | -0.81[111] | 0.07[112] |
17 | SMAD3 | Mothers against decapentaplegic homolog 3 | [113] | 0.74[114] | 0.57[115] | 1.57[116] | 1.17[117] | 1.21[118] | -0.17[119] |
18 | SMAD1 | Mothers against decapentaplegic homolog 1 | [120] | -2.24[121] | -1.55[122] | -0.49[123] | -1.35[124] | -1.64[125] | 0.24[126] |
19 | TGFBR1 | TGF-beta receptor type-1 | [127] | -0.86[128] | -0.20[129] | 0.07[130] | -0.28[131] | -0.02[132] | 0.95[133] |
20 | MAPK9 | Mitogen-activated protein kinase 9 | [134] | 0.04[135] | 0.69[136] | 1.53[137] | 1.09[138] | -0.30[139] | 0.12[140] |
21 | MAPK3 | Mitogen-activated protein kinase 3 | [141] | 0.66[142] | 1.14[143] | 1.95[144] | -0.20[145] | -1.02[146] | -1.43[147] |
22 | SMAD7 | Mothers against decapentaplegic homolog 7 | [148] | 0.67[149] | -0.79[150] | -1.03[151] | -0.04[152] | -1.18[153] | -0.38[154] |
23 | FST | Follistatin | [155] | -1.23[156] | 0.86[157] | -2.07[158] | -5.38[159] | -4.95[160] | -0.34[161] |
24 | SKI | Ski oncogene | [162] | 1.28[163] | 1.41[164] | 1.66[165] | 1.54[166] | 1.04[167] | 0.65[168] |
25 | SMAD4 | Mothers against decapentaplegic homolog 4 | [169] | 0.20[170] | 1.26[171] | 2.00[172] | 1.29[173] | 0.81[174] | 2.41[175] |
26 | SMAD5 | Mothers against decapentaplegic homolog 5 | [176] | 0.64[177] | 1.77[178] | 2.32[179] | 2.02[180] | 1.22[181] | 2.57[182] |
27 | SMAD2 | Mothers against decapentaplegic homolog 2 | [183] | 0.83[184] | 1.52[185] | 1.79[186] | 1.76[187] | 1.10[188] | 2.18[189] |
28 | EP300 | Histone acetyltransferase p300 | [190] | 1.53[191] | 1.56[192] | 3.22[193] | 1.95[194] | 1.15[195] | 2.37[196] |
29 | TGFB1 | Transforming growth factor beta-1 | [197] | 2.28[198] | 1.67[199] | -0.30[200] | 3.21[201] | 1.60[202] | -1.61[203] |
30 | SKIL | Ski-like protein | [204] | 0.47[205] | 0.94[206] | 3.17[207] | 2.01[208] | 1.19[209] | 2.77[210] |
31 | ZFYVE9 | Zinc finger FYVE domain-containing protein 9 | [211] | 0.45[212] | 1.12[213] | 1.85[214] | 0.98[215] | 0.58[216] | 1.82[217] |
32 | TGFBR3 | Transforming growth factor beta receptor type 3 | [218] | 1.10[219] | 3.58[220] | 2.92[221] | 1.23[222] | -1.29[223] | 2.59[224] |
33 | CREBBP | CREB-binding protein | [225] | 1.71[226] | 1.36[227] | 2.74[228] | 2.13[229] | 1.29[230] | 2.85[231] |
34 | LTBP1 | Latent-transforming growth factor beta-binding protein 1 | [232] | -1.94[233] | -7.57[234] | -0.76[235] | 1.64[236] | 1.01[237] | 2.00[238] |
35 | BMP4 | Bone morphogenetic protein 4 | [239] | 3.30[240] | 2.96[241] | 0.66[242] | 1.38[243] | -1.61[244] | -1.57[245] |
36 | LIF | Leukemia inhibitory factor | [246] | 1.09[247] | 1.36[248] | 2.96[249] | 0.99[250] | 1.16[251] | -5.57[252] |
37 | ENG | Endoglin | [253] | -2.08[254] | 0.15[255] | -5.09[256] | 2.42[257] | -2.28[258] | 3.52[259] |
38 | SMAD6 | Mothers against decapentaplegic homolog 6 | [260] | 0.22[261] | -1.09[262] | 0.11[263] | 0.83[264] | -1.57[265] | 0.47[266] |
39 | INHBA | Inhibin beta A chain | [267] | -8.68[268] | -7.96[269] | -6.74[270] | 2.30[271] | -2.15[272] | 0.22[273] |
40 | LEFTY1 | Left-right determination factor 1 | [274] | -1.73[275] | -2.78[276] | -0.77[277] | -5.19[278] | -5.98[279] | -1.32[280] |
41 | ZEB2 | Zinc finger E-box-binding homeobox 2 | [281] | -1.81[282] | -5.72[283] | -4.44[284] | 4.18[285] | 4.24[286] | 5.13[287] |
42 | SMAD9 | Mothers against decapentaplegic homolog 9 | [288] | 2.79[289] | 2.91[290] | 2.95[291] | 1.57[292] | 2.24[293] | 2.49[294] |
43 | ITGB6 | Integrin beta-6 | [295] | [296] | [297] | [298] | -1.72[299] | -5.37[300] | -3.15[301] |
44 | IFNG | Interferon gamma | [302] | [303] | [304] | [305] | -1.32[306] | [307] | -2.68[308] |
45 | RUNX3 | Runt-related transcription factor 3 | [309] | -0.43[310] | -0.98[311] | 2.78[312] | 2.94[313] | -3.09[314] | 0.98[315] |
46 | TNF | Tumor necrosis factor | [316] | -0.09[317] | -1.79[318] | -5.62[319] | -2.85[320] | -6.91[321] | -2.28[322] |
47 | FOXH1 | Forkhead box protein H1 | [323] | -4.13[324] | 2.07[325] | -3.94[326] | -3.67[327] | -4.58[328] | -3.61[329] |
48 | LEFTY2 | Left-right determination factor 2 | [330] | -0.93[331] | -0.69[332] | 3.07[333] | -0.43[334] | -5.85[335] | -2.41[336] |
49 | LEF1 | Lymphoid enhancer-binding factor 1 | [337] | 1.46[338] | -5.03[339] | 3.66[340] | 0.46[341] | -2.09[342] | 0.70[343] |
50 | ZNF423 | Zinc finger protein 423 | [344] | 0.41[345] | -4.66[346] | 0.80[347] | 0.82[348] | -4.19[349] | 3.09[350] |
51 | RUNX2 | Runt-related transcription factor 2 | [351] | -2.04[352] | -1.96[353] | 3.88[354] | 6.50[355] | 7.61[356] | 3.24[357] |
52 | EGF | Pro-epidermal growth factor | [358] | 0.78[359] | 3.00[360] | 7.38[361] | 8.40[362] | 4.98[363] | 1.19[364] |
53 | NOG | Noggin | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | MIR302A | [372] | [373] | [374] | [375] | [376] | [377] | [378] | |
55 | WNT1 | Proto-oncogene Wnt-1 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | MIR6869 | [386] | [387] | [388] | [389] | [390] | [391] | [392] | |
57 | LINC02478 | [393] | [394] | [395] | [396] | [397] | [398] | [399] | |
58 | MIR1281 | [400] | [401] | [402] | [403] | [404] | [405] | [406] |