WP_TCA_CYCLE_IN_SENESCENCE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GOT1 Aspartate aminotransferase, cytoplasmic [1] -0.61[2] 0.31[3] -1.02[4] -3.39[5] -2.01[6] 0.24[7]
2 MDH1 Malate dehydrogenase, cytoplasmic [8] 0.05[9] -0.06[10] -0.42[11] -0.07[12] 0.01[13] -0.74[14]
3 FH Fumarate hydratase, mitochondrial [15] -0.89[16] -1.38[17] -0.96[18] -0.39[19] -0.44[20] -0.02[21]
4 PDHA1 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial -0.10[22] -0.83[23] 0.41[24] -0.10[25] -0.11[26] -0.01[27]
5 TP53 Cellular tumor antigen p53 [28] 2.32[29] 1.16[30] 2.14[31] 1.73[32] 1.85[33] -0.20[34]
6 ME1 NADP-dependent malic enzyme [35] -5.66[36] -5.75[37] 2.61[38] 3.34[39] 2.27[40] 0.37[41]
7 ME2 NAD-dependent malic enzyme, mitochondrial [42] 1.55[43] 0.70[44] 1.42[45] 2.34[46] 3.16[47] 1.05[48]
8 PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 3.05[49] 3.04[50] 2.88[51] 3.05[52] 1.73[53] 1.91[54]
9 PDP2 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial 2.59[55] 2.25[56] 3.04[57] 2.23[58] 2.36[59] 2.25[60]
10 BRAF Serine/threonine-protein kinase B-raf [61] 0.93[62] -0.06[63] 2.19[64] 1.18[65] 1.33[66] 1.70[67]
[1]
ref_hepatocyte GOT1
Mean 75.1
Standard deviation 57
Values 62 1.1e+02 1.5e+02 6.4 44
[2]
HepG2 GOT1
Mean 67.6
Standard deviation 26
Values 49 86
[3]
HepG2.C3A GOT1
Mean 188
Standard deviation 68
Values 1.4e+02 2.4e+02
[4]
HuH.7 GOT1
Mean 61.7
Standard deviation 15
Values 75 45 65
[5]
SNU475 GOT1
Mean 9.68
Standard deviation 0.11
Values 9.8 9.6
[6]
THLE GOT1
Mean 20.6
Standard deviation 1.6
Values 20 22
[7]
liver GOT1
Mean 140
Standard deviation 1e+02
Values 51 1.1e+02 1.1e+02 2.8e+02
[8]
ref_hepatocyte MDH1
Mean 74.5
Standard deviation 43
Values 9.2 1.1e+02 1e+02 99 52
[9]
HepG2 MDH1
Mean 106
Standard deviation 36
Values 1.3e+02 80
[10]
HepG2.C3A MDH1
Mean 144
Standard deviation 49
Values 1.8e+02 1.1e+02
[11]
HuH.7 MDH1
Mean 93.1
Standard deviation 25
Values 1.2e+02 67 96
[12]
SNU475 MDH1
Mean 95.9
Standard deviation 44
Values 65 1.3e+02
[13]
THLE MDH1
Mean 83.2
Standard deviation 9.4
Values 77 90
[14]
liver MDH1
Mean 70.6
Standard deviation 50
Values 22 34 1.2e+02 1.1e+02
[15]
ref_hepatocyte FH
Mean 43.1
Standard deviation 38
Values 8.7 78 91 17 21
[16]
HepG2 FH
Mean 32
Standard deviation 8
Values 38 26
[17]
HepG2.C3A FH
Mean 33.4
Standard deviation 7.2
Values 39 28
[18]
HuH.7 FH
Mean 37.1
Standard deviation 6.3
Values 43 31 38
[19]
SNU475 FH
Mean 44.6
Standard deviation 4.8
Values 41 48
[20]
THLE FH
Mean 35.3
Standard deviation 6.3
Values 31 40
[21]
liver FH
Mean 67.3
Standard deviation 23
Values 42 55 82 90
[22]
ref_hepatocyte PDHA1
Mean 24.9
Standard deviation 8.4
Values 16 20 25 25 38
[23]
HepG2 PDHA1
Mean 32
Standard deviation 3.7
Values 35 29
[24]
HepG2.C3A PDHA1
Mean 28.2
Standard deviation 0.42
Values 28 28
[25]
HuH.7 PDHA1
Mean 55
Standard deviation 18
Values 67 34 64
[26]
SNU475 PDHA1
Mean 31.4
Standard deviation 0.34
Values 31 32
[27]
THLE PDHA1
Mean 25.6
Standard deviation 3
Values 24 28
[28]
liver PDHA1
Mean 39.1
Standard deviation 23
Values 17 22 54 63
[29]
ref_hepatocyte TP53
Mean 5.28
Standard deviation 0.94
Values 6.2 5.5 5.5 5.5 3.7
[30]
HepG2 TP53
Mean 36.3
Standard deviation 0.12
Values 36 36
[31]
HepG2.C3A TP53
Mean 23.9
Standard deviation 1.8
Values 25 23
[32]
HuH.7 TP53
Mean 38.7
Standard deviation 16
Values 46 20 50
[33]
SNU475 TP53
Mean 23.7
Standard deviation 6.7
Values 19 28
[34]
THLE TP53
Mean 21.1
Standard deviation 6.6
Values 16 26
[35]
liver TP53
Mean 7.29
Standard deviation 2.3
Values 5.6 5 9 9.5
[36]
ref_hepatocyte ME1
Mean 4.08
Standard deviation 4.6
Values 2.3 2 4.3 0.033 12
[37]
HepG2 ME1
Mean 0.111
Standard deviation 0.019
Values 0.12 0.097
[38]
HepG2.C3A ME1
Mean 0.153
Standard deviation 0.0038
Values 0.15 0.16
[39]
HuH.7 ME1
Mean 41.5
Standard deviation 4.1
Values 45 37 42
[40]
SNU475 ME1
Mean 55.8
Standard deviation 9
Values 49 62
[41]
THLE ME1
Mean 21.9
Standard deviation 0.18
Values 22 22
[42]
liver ME1
Mean 8.33
Standard deviation 4.2
Values 3.3 6.5 12 11
[43]
ref_hepatocyte ME2
Mean 3.58
Standard deviation 2.1
Values 4.5 1.9 2.2 2.4 6.9
[44]
HepG2 ME2
Mean 14.4
Standard deviation 2.8
Values 16 12
[45]
HepG2.C3A ME2
Mean 11.7
Standard deviation 3.5
Values 14 9.2
[46]
HuH.7 ME2
Mean 16
Standard deviation 2.5
Values 17 13 18
[47]
SNU475 ME2
Mean 24.6
Standard deviation 2.3
Values 23 26
[48]
THLE ME2
Mean 35.5
Standard deviation 2.3
Values 34 37
[49]
liver ME2
Mean 11.7
Standard deviation 2.3
Values 9.1 14 10 13
[50]
ref_hepatocyte PDK1
Mean 1.82
Standard deviation 1.1
Values 0.89 2.1 1.1 3.7 1.3
[51]
HepG2 PDK1
Mean 20.7
Standard deviation 5.2
Values 24 17
[52]
HepG2.C3A PDK1
Mean 30.3
Standard deviation 3.9
Values 33 28
[53]
HuH.7 PDK1
Mean 22.3
Standard deviation 0.9
Values 21 22 23
[54]
SNU475 PDK1
Mean 20.4
Standard deviation 4.6
Values 17 24
[55]
THLE PDK1
Mean 6.71
Standard deviation 0.29
Values 6.5 6.9
[56]
liver PDK1
Mean 10.8
Standard deviation 3
Values 7.1 12 10 14
[57]
ref_hepatocyte PDP2
Mean 1.33
Standard deviation 0.54
Values 1 1.9 0.93 1.9 0.85
[58]
HepG2 PDP2
Mean 11
Standard deviation 1.3
Values 10 12
[59]
HepG2.C3A PDP2
Mean 12.8
Standard deviation 1.3
Values 12 14
[60]
HuH.7 PDP2
Mean 18.3
Standard deviation 2.6
Values 16 21 18
[61]
SNU475 PDP2
Mean 8.5
Standard deviation 0.56
Values 8.1 8.9
[62]
THLE PDP2
Mean 7.59
Standard deviation 1.4
Values 6.6 8.6
[63]
liver PDP2
Mean 10.1
Standard deviation 3.5
Values 8.7 15 6.2 11
[64]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 2.3 0.67 0.67 0.56 1.2
[65]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 3.2 2.4
[66]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 2.5 1.6
[67]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 3.4 15 6.4
[68]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.4 3.2
[69]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[70]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 7.9 8 3.1 2.9