WP_TCA_CYCLE_AKA_KREBS_OR_CITRIC_ACID_CYCLE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IDH2 Isocitrate dehydrogenase [NADP], mitochondrial [1] -1.12[2] -1.55[3] -0.95[4] -1.65[5] -2.86[6] -0.13[7]
2 MDH2 Malate dehydrogenase, mitochondrial [8] -0.19[9] -0.76[10] -0.12[11] -0.39[12] -0.83[13] -0.29[14]
3 SDHB Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial -1.14[15] -0.53[16] -1.20[17] -1.23[18] -0.95[19] -0.34[20]
4 SDHA Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial -0.33[21] -0.64[22] -0.60[23] -0.67[24] 0.02[25] 0.24[26]
5 SDHD Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial -0.53[27] -0.51[28] -1.00[29] -0.04[30] -0.19[31] 0.42[32]
6 SUCLG2 Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial [33] -1.18[34] -0.74[35] -0.94[36] -1.69[37] -0.90[38] 0.08[39]
7 SUCLG1 Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial -0.80[40] -0.32[41] 0.74[42] -0.97[43] -0.58[44] -0.43[45]
8 FH Fumarate hydratase, mitochondrial [46] -0.67[47] -0.52[48] -0.15[49] 0.34[50] -0.04[51] 0.31[52]
9 DLD Dihydrolipoyl dehydrogenase, mitochondrial [53] -0.23[54] 0.40[55] 0.39[56] 0.90[57] 0.48[58] 0.26[59]
10 SDHC Succinate dehydrogenase cytochrome b560 subunit, mitochondrial [60] 1.19[61] 1.14[62] 0.88[63] 1.61[64] 1.33[65] -0.59[66]
11 IDH3B Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial [67] 0.71[68] 0.86[69] 0.19[70] 0.21[71] 0.40[72] -0.64[73]
12 DLST Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial 1.36[74] 1.79[75] 0.88[76] 1.47[77] 1.71[78] -0.39[79]
13 ACO2 Aconitate hydratase, mitochondrial [80] 0.68[81] 0.67[82] 0.96[83] 0.14[84] 0.42[85] 0.41[86]
14 CS Citrate synthase, mitochondrial [87] 3.24[88] 2.93[89] 2.54[90] 2.39[91] 2.57[92] 0.48[93]
15 IDH3G Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial [94] -0.30[95] -0.20[96] 0.13[97] 0.83[98] 0.55[99] -0.20[100]
16 SUCLA2 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial [101] 0.04[102] 1.10[103] 0.25[104] 0.25[105] 1.00[106] -0.06[107]
17 OGDH 2-oxoglutarate dehydrogenase, mitochondrial [108] 1.65[109] 0.96[110] 2.01[111] 2.21[112] 2.27[113] 1.46[114]
18 IDH3A Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial [115] 0.46[116] 0.91[117] 0.08[118] 1.41[119] 1.90[120] 0.92[121]
[1]
ref_hepatocyte IDH2
Mean 157
Standard deviation 1.1e+02
Values 30 2.4e+02 2.6e+02 2e+02 52
[2]
HepG2 IDH2
Mean 85
Standard deviation 1.2
Values 84 86
[3]
HepG2.C3A IDH2
Mean 59.2
Standard deviation 12
Values 51 68
[4]
HuH.7 IDH2
Mean 77.5
Standard deviation 6.5
Values 79 70 83
[5]
SNU475 IDH2
Mean 40.8
Standard deviation 22
Values 26 56
[6]
THLE IDH2
Mean 18.2
Standard deviation 1.2
Values 17 19
[7]
liver IDH2
Mean 181
Standard deviation 68
Values 1.4e+02 1.1e+02 2.1e+02 2.6e+02
[8]
ref_hepatocyte MDH2
Mean 104
Standard deviation 75
Values 77 1.3e+02 2.2e+02 38 53
[9]
HepG2 MDH2
Mean 107
Standard deviation 16
Values 96 1.2e+02
[10]
HepG2.C3A MDH2
Mean 67.7
Standard deviation 5.8
Values 64 72
[11]
HuH.7 MDH2
Mean 91.1
Standard deviation 31
Values 98 57 1.2e+02
[12]
SNU475 MDH2
Mean 64.7
Standard deviation 14
Values 55 74
[13]
THLE MDH2
Mean 49
Standard deviation 8.8
Values 43 55
[14]
liver MDH2
Mean 107
Standard deviation 92
Values 29 26 1.7e+02 2e+02
[15]
ref_hepatocyte SDHB
Mean 81.4
Standard deviation 76
Values 43 1.6e+02 1.7e+02 14 23
[16]
HepG2 SDHB
Mean 43.4
Standard deviation 2.6
Values 45 42
[17]
HepG2.C3A SDHB
Mean 62.7
Standard deviation 9.9
Values 70 56
[18]
HuH.7 SDHB
Mean 33.9
Standard deviation 12
Values 46 22 34
[19]
SNU475 SDHB
Mean 28.4
Standard deviation 0.73
Values 28 29
[20]
THLE SDHB
Mean 35.4
Standard deviation 4.1
Values 33 38
[21]
liver SDHB
Mean 81
Standard deviation 60
Values 23 36 1.4e+02 1.3e+02
[22]
ref_hepatocyte SDHA
Mean 64.8
Standard deviation 32
Values 36 1.1e+02 93 47 43
[23]
HepG2 SDHA
Mean 60.8
Standard deviation 7
Values 66 56
[24]
HepG2.C3A SDHA
Mean 46
Standard deviation 2.9
Values 44 48
[25]
HuH.7 SDHA
Mean 40.8
Standard deviation 11
Values 47 28 48
[26]
SNU475 SDHA
Mean 33.3
Standard deviation 7.3
Values 28 38
[27]
THLE SDHA
Mean 55.2
Standard deviation 3.8
Values 53 58
[28]
liver SDHA
Mean 96.7
Standard deviation 39
Values 61 78 97 1.5e+02
[29]
ref_hepatocyte SDHD
Mean 63.7
Standard deviation 69
Values 21 1.7e+02 92 12 21
[30]
HepG2 SDHD
Mean 51.9
Standard deviation 13
Values 61 42
[31]
HepG2.C3A SDHD
Mean 49.6
Standard deviation 13
Values 59 40
[32]
HuH.7 SDHD
Mean 30.4
Standard deviation 8.6
Values 39 22 30
[33]
SNU475 SDHD
Mean 50.5
Standard deviation 13
Values 42 59
[34]
THLE SDHD
Mean 46.9
Standard deviation 3.1
Values 45 49
[35]
liver SDHD
Mean 107
Standard deviation 77
Values 32 50 1.6e+02 1.8e+02
[36]
ref_hepatocyte SUCLG2
Mean 52.6
Standard deviation 48
Values 14 1.3e+02 71 15 33
[37]
HepG2 SUCLG2
Mean 27.4
Standard deviation 5.7
Values 31 23
[38]
HepG2.C3A SUCLG2
Mean 34.7
Standard deviation 8.9
Values 41 28
[39]
HuH.7 SUCLG2
Mean 26.2
Standard deviation 0.91
Values 26 26 27
[40]
SNU475 SUCLG2
Mean 13.3
Standard deviation 5.2
Values 9.7 17
[41]
THLE SUCLG2
Mean 23.8
Standard deviation 4.1
Values 21 27
[42]
liver SUCLG2
Mean 69.9
Standard deviation 18
Values 48 63 77 91
[43]
ref_hepatocyte SUCLG1
Mean 51.8
Standard deviation 25
Values 25 71 85 36 42
[44]
HepG2 SUCLG1
Mean 35
Standard deviation 6.7
Values 40 30
[45]
HepG2.C3A SUCLG1
Mean 46
Standard deviation 6.9
Values 51 41
[46]
HuH.7 SUCLG1
Mean 82.9
Standard deviation 9.5
Values 94 78 77
[47]
SNU475 SUCLG1
Mean 21.5
Standard deviation 1.6
Values 20 23
[48]
THLE SUCLG1
Mean 29.3
Standard deviation 2.7
Values 27 31
[49]
liver SUCLG1
Mean 48.5
Standard deviation 38
Values 14 18 89 73
[50]
ref_hepatocyte FH
Mean 43.1
Standard deviation 38
Values 8.7 78 91 17 21
[51]
HepG2 FH
Mean 32
Standard deviation 8
Values 38 26
[52]
HepG2.C3A FH
Mean 33.4
Standard deviation 7.2
Values 39 28
[53]
HuH.7 FH
Mean 37.1
Standard deviation 6.3
Values 43 31 38
[54]
SNU475 FH
Mean 44.6
Standard deviation 4.8
Values 41 48
[55]
THLE FH
Mean 35.3
Standard deviation 6.3
Values 31 40
[56]
liver FH
Mean 67.3
Standard deviation 23
Values 42 55 82 90
[57]
ref_hepatocyte DLD
Mean 31.7
Standard deviation 25
Values 13 19 16 39 73
[58]
HepG2 DLD
Mean 31.9
Standard deviation 11
Values 39 24
[59]
HepG2.C3A DLD
Mean 46.4
Standard deviation 13
Values 56 37
[60]
HuH.7 DLD
Mean 39.8
Standard deviation 5.6
Values 43 33 44
[61]
SNU475 DLD
Mean 48.2
Standard deviation 1.7
Values 47 49
[62]
THLE DLD
Mean 37.3
Standard deviation 2.8
Values 35 39
[63]
liver DLD
Mean 47.9
Standard deviation 25
Values 20 37 56 79
[64]
ref_hepatocyte SDHC
Mean 28.6
Standard deviation 18
Values 5.1 52 39 22 25
[65]
HepG2 SDHC
Mean 76.9
Standard deviation 9.9
Values 84 70
[66]
HepG2.C3A SDHC
Mean 70
Standard deviation 21
Values 85 55
[67]
HuH.7 SDHC
Mean 50.2
Standard deviation 12
Values 60 37 54
[68]
SNU475 SDHC
Mean 71.2
Standard deviation 19
Values 58 85
[69]
THLE SDHC
Mean 60.4
Standard deviation 12
Values 52 69
[70]
liver SDHC
Mean 24
Standard deviation 9.1
Values 16 17 27 35
[71]
ref_hepatocyte IDH3B
Mean 28.3
Standard deviation 6.5
Values 37 20 30 31 25
[72]
HepG2 IDH3B
Mean 54.6
Standard deviation 1.5
Values 54 56
[73]
HepG2.C3A IDH3B
Mean 56.9
Standard deviation 3.4
Values 59 55
[74]
HuH.7 IDH3B
Mean 30.9
Standard deviation 9.2
Values 39 21 33
[75]
SNU475 IDH3B
Mean 26.7
Standard deviation 4.1
Values 30 24
[76]
THLE IDH3B
Mean 31.5
Standard deviation 3.2
Values 29 34
[77]
liver IDH3B
Mean 22.9
Standard deviation 10
Values 14 15 31 32
[78]
ref_hepatocyte DLST
Mean 19.4
Standard deviation 4.5
Values 24 19 22 12 20
[79]
HepG2 DLST
Mean 58.7
Standard deviation 1.6
Values 58 60
[80]
HepG2.C3A DLST
Mean 74.5
Standard deviation 3.3
Values 72 77
[81]
HuH.7 DLST
Mean 34.1
Standard deviation 5.6
Values 39 28 36
[82]
SNU475 DLST
Mean 43.8
Standard deviation 3.5
Values 41 46
[83]
THLE DLST
Mean 53.2
Standard deviation 2.1
Values 52 55
[84]
liver DLST
Mean 18.7
Standard deviation 14
Values 28 33 6.4 6.7
[85]
ref_hepatocyte ACO2
Mean 19
Standard deviation 5.5
Values 13 22 26 20 14
[86]
HepG2 ACO2
Mean 36.1
Standard deviation 0.091
Values 36 36
[87]
HepG2.C3A ACO2
Mean 33.5
Standard deviation 6
Values 29 38
[88]
HuH.7 ACO2
Mean 35.4
Standard deviation 5.1
Values 32 33 41
[89]
SNU475 ACO2
Mean 17.1
Standard deviation 6.3
Values 13 22
[90]
THLE ACO2
Mean 21.5
Standard deviation 7.4
Values 16 27
[91]
liver ACO2
Mean 31.8
Standard deviation 8.4
Values 29 29 25 44
[92]
ref_hepatocyte CS
Mean 15.3
Standard deviation 5.2
Values 19 12 13 23 9.8
[93]
HepG2 CS
Mean 170
Standard deviation 16
Values 1.8e+02 1.6e+02
[94]
HepG2.C3A CS
Mean 129
Standard deviation 6.5
Values 1.2e+02 1.3e+02
[95]
HuH.7 CS
Mean 85.2
Standard deviation 12
Values 86 73 96
[96]
SNU475 CS
Mean 65.5
Standard deviation 9.6
Values 59 72
[97]
THLE CS
Mean 76.6
Standard deviation 19
Values 63 90
[98]
liver CS
Mean 26.9
Standard deviation 9.6
Values 20 18 31 38
[99]
ref_hepatocyte IDH3G
Mean 13.3
Standard deviation 5.7
Values 14 14 22 6.6 11
[100]
HepG2 IDH3G
Mean 12.7
Standard deviation 1.8
Values 14 11
[101]
HepG2.C3A IDH3G
Mean 12.8
Standard deviation 3.2
Values 11 15
[102]
HuH.7 IDH3G
Mean 14
Standard deviation 3.5
Values 15 10 17
[103]
SNU475 IDH3G
Mean 19.3
Standard deviation 5
Values 16 23
[104]
THLE IDH3G
Mean 16.4
Standard deviation 1.5
Values 15 17
[105]
liver IDH3G
Mean 14.6
Standard deviation 9.7
Values 6.7 6.4 19 26
[106]
ref_hepatocyte SUCLA2
Mean 11.9
Standard deviation 8.1
Values 5.1 9.7 5 24 16
[107]
HepG2 SUCLA2
Mean 14.5
Standard deviation 6.2
Values 19 10
[108]
HepG2.C3A SUCLA2
Mean 28.3
Standard deviation 6.8
Values 33 23
[109]
HuH.7 SUCLA2
Mean 13.6
Standard deviation 0.97
Values 15 13 13
[110]
SNU475 SUCLA2
Mean 11.5
Standard deviation 1.5
Values 10 13
[111]
THLE SUCLA2
Mean 20.1
Standard deviation 0.15
Values 20 20
[112]
liver SUCLA2
Mean 14.4
Standard deviation 5.4
Values 8.4 11 18 20
[113]
ref_hepatocyte OGDH
Mean 9.59
Standard deviation 2.6
Values 12 7.8 11 6.1 11
[114]
HepG2 OGDH
Mean 35.5
Standard deviation 0.48
Values 36 35
[115]
HepG2.C3A OGDH
Mean 20.6
Standard deviation 2.9
Values 19 23
[116]
HuH.7 OGDH
Mean 37
Standard deviation 11
Values 38 26 47
[117]
SNU475 OGDH
Mean 36.2
Standard deviation 8.1
Values 31 42
[118]
THLE OGDH
Mean 38.9
Standard deviation 6
Values 35 43
[119]
liver OGDH
Mean 33.2
Standard deviation 11
Values 45 41 21 26
[120]
ref_hepatocyte IDH3A
Mean 8.88
Standard deviation 1.1
Values 8.8 8.3 10 7.4 9.8
[121]
HepG2 IDH3A
Mean 14.4
Standard deviation 2.4
Values 16 13
[122]
HepG2.C3A IDH3A
Mean 18.5
Standard deviation 3.9
Values 21 16
[123]
HuH.7 IDH3A
Mean 8.96
Standard deviation 1.7
Values 9.9 7 10
[124]
SNU475 IDH3A
Mean 19.2
Standard deviation 3.3
Values 22 17
[125]
THLE IDH3A
Mean 28
Standard deviation 4
Values 25 31
[126]
liver IDH3A
Mean 21.2
Standard deviation 6.2
Values 13 19 25 27