WP_SYNAPTIC_SIGNALING_PATHWAYS_ASSOCIATED_WITH_AUTISM_SPECTRUM_DISORDER Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RHEB GTP-binding protein Rheb [1] -2.14[2] -1.89[3] -2.16[4] -1.59[5] -1.37[6] -1.76[7]
2 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 [8] -1.18[9] -1.83[10] -1.42[11] -3.78[12] -2.13[13] -2.27[14]
3 AKT1 RAC-alpha serine/threonine-protein kinase [15] -0.11[16] -0.67[17] -1.95[18] -0.53[19] -0.40[20] -0.92[21]
4 PRKAG1 5'-AMP-activated protein kinase subunit gamma-1 [22] -1.61[23] -1.40[24] -1.48[25] -0.83[26] -1.01[27] -2.32[28]
5 NRAS GTPase NRas [29] 0.44[30] 0.54[31] 0.76[32] 0.51[33] 0.19[34] -0.92[35]
6 PRKAG2 5'-AMP-activated protein kinase subunit gamma-2 [36] -4.25[37] -9.68[38] -3.44[39] -2.22[40] -1.97[41] -1.14[42]
7 HRAS GTPase HRas [43] -1.20[44] -2.23[45] -3.22[46] -1.43[47] -1.54[48] -3.33[49]
8 MAPK1 Mitogen-activated protein kinase 1 [50] 1.52[51] 1.33[52] 0.96[53] 1.37[54] 1.12[55] 1.11[56]
9 AKT2 RAC-beta serine/threonine-protein kinase [57] 0.77[58] 0.71[59] 0.65[60] 0.37[61] 0.27[62] 0.46[63]
10 UBE3A Ubiquitin-protein ligase E3A [64] -0.49[65] 0.00[66] -0.17[67] 0.30[68] 0.30[69] 0.55[70]
11 KRAS GTPase KRas [71] -0.71[72] -1.06[73] 0.35[74] 0.32[75] 0.09[76] 0.00[77]
12 PRKAA1 5'-AMP-activated protein kinase catalytic subunit alpha-1 [78] -0.27[79] 0.68[80] 2.00[81] 0.98[82] 1.36[83] 1.39[84]
13 PRKAB2 5'-AMP-activated protein kinase subunit beta-2 [85] 0.69[86] 1.55[87] 1.47[88] 0.54[89] -0.38[90] 0.74[91]
14 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [92] -0.66[93] -0.87[94] 0.02[95] 1.58[96] 1.19[97] 2.33[98]
15 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -0.73[99] 0.33[100] 0.34[101] -1.05[102] 0.31[103] 1.81[104]
16 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [105] 1.68[106] 1.58[107] 1.99[108] 0.22[109] 0.89[110] -0.96[111]
17 PRKAB1 5'-AMP-activated protein kinase subunit beta-1 [112] 0.52[113] 0.72[114] -0.32[115] -0.55[116] -0.33[117] -0.67[118]
18 MAPK3 Mitogen-activated protein kinase 3 [119] 1.66[120] 1.38[121] 1.22[122] -0.06[123] 0.07[124] -1.71[125]
19 GSK3B Glycogen synthase kinase-3 beta [126] 1.07[127] 0.38[128] 0.76[129] 1.33[130] 1.27[131] 0.49[132]
20 MTOR Serine/threonine-protein kinase mTOR [133] 2.34[134] 3.03[135] 2.40[136] 2.20[137] 2.39[138] 2.78[139]
21 TSC2 Tuberin [140] 1.62[141] 0.82[142] 1.31[143] 0.72[144] 1.35[145] 1.41[146]
22 RPS6KB1 Ribosomal protein S6 kinase beta-1 [147] [148] [149] [150] [151] [152] [153]
23 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 1.02[154] 1.20[155] 1.16[156] 0.57[157] 0.83[158] 0.49[159]
24 RPTOR Regulatory-associated protein of mTOR [160] 2.89[161] 1.80[162] 1.71[163] 1.36[164] 1.71[165] 1.67[166]
25 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -0.57[167] 0.74[168] 0.73[169] 0.65[170] 0.96[171] 1.24[172]
26 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1.69[173] 2.45[174] -1.55[175] -0.20[176] 0.67[177] -0.37[178]
27 TSC1 Hamartin [179] 1.70[180] 2.03[181] 1.98[182] 1.58[183] 1.89[184] 2.09[185]
28 NF1 Neurofibromin [186] 2.27[187] 2.28[188] 2.90[189] 3.49[190] 3.04[191] 3.44[192]
29 HOMER1 Homer protein homolog 1 [193] 1.23[194] 1.85[195] 2.38[196] 1.04[197] 0.86[198] -1.19[199]
30 SHANK3 SH3 and multiple ankyrin repeat domains protein 3 [200] 2.95[201] 2.42[202] 2.34[203] 0.56[204] -0.62[205] 2.31[206]
31 PRKAA2 5'-AMP-activated protein kinase catalytic subunit alpha-2 [207] 2.84[208] 2.96[209] 2.79[210] 2.56[211] 0.71[212] 1.18[213]
32 CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta [214] -2.73[215] -4.38[216] -7.53[217] -3.34[218] -2.60[219] 0.48[220]
33 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [221] 1.53[222] 1.21[223] 1.86[224] 2.68[225] 1.81[226] 2.01[227]
34 AKT3 RAC-gamma serine/threonine-protein kinase [228] -2.03[229] -4.92[230] -4.43[231] 5.36[232] 4.42[233] 2.94[234]
35 DLG4 Disks large homolog 4 [235] 2.59[236] 2.55[237] 1.11[238] 1.48[239] 3.80[240] 1.03[241]
36 SYNGAP1 Ras/Rap GTPase-activating protein SynGAP [242] 3.00[243] 2.64[244] 2.50[245] 4.40[246] 4.94[247] 1.21[248]
37 ARC Activity-regulated cytoskeleton-associated protein [249] -2.60[250] -0.74[251] -5.17[252] -1.84[253] 1.91[254] -4.19[255]
38 GRIN2D Glutamate receptor ionotropic, NMDA 2D [256] 4.30[257] 3.86[258] 3.99[259] 2.30[260] 1.36[261] -0.72[262]
39 BDNF Brain-derived neurotrophic factor [263] -1.85[264] -4.95[265] -3.22[266] 6.26[267] 5.13[268] 1.43[269]
40 GRIN3A Glutamate receptor ionotropic, NMDA 3A [270] -1.36[271] 0.28[272] 0.27[273] 0.98[274] 0.03[275] 2.91[276]
41 CAMK4 Calcium/calmodulin-dependent protein kinase type IV [277] [278] -2.28[279] -3.14[280] 0.96[281] 3.14[282] 3.58[283]
42 GRIN3B Glutamate receptor ionotropic, NMDA 3B [284] 3.77[285] 2.15[286] 2.57[287] -0.20[288] 2.79[289] 1.53[290]
43 GRIN2B Glutamate receptor ionotropic, NMDA 2B [291] -2.65[292] [293] [294] 0.61[295] -2.10[296] 1.19[297]
44 PRKAG3 5'-AMP-activated protein kinase subunit gamma-3 [298] -1.93[299] [300] -2.78[301] -1.50[302] [303] 2.45[304]
45 GRIN2C Glutamate receptor ionotropic, NMDA 2C [305] 3.40[306] 4.72[307] 3.13[308] 3.00[309] 3.74[310] 3.27[311]
46 CACNA1C Voltage-dependent L-type calcium channel subunit alpha-1C [312] 4.53[313] 1.70[314] 4.37[315] 5.24[316] 7.58[317] 7.64[318]
47 GRIN2A Glutamate receptor ionotropic, NMDA 2A [319] [320] [321] -1.32[322] 8.57[323] 1.21[324] 7.36[325]
48 GRM1 Metabotropic glutamate receptor 1 [326] 2.06[327] [328] -0.30[329] 5.09[330] 2.94[331] 2.46[332]
49 MIR5004 [333] [334] [335] [336] [337] [338] [339]
50 GRIN1 Glutamate receptor ionotropic, NMDA 1 [340] [341] [342] [343] [344] [345] [346]
51 NTRK2 BDNF/NT-3 growth factors receptor [347] [348] [349] [350] [351] [352] [353]
[1]
ref_hepatocyte RHEB
Mean 67.3
Standard deviation 38
Values 1.1e+02 33 29 64 96
[2]
HepG2 RHEB
Mean 38.6
Standard deviation 1.7
Values 37 40
[3]
HepG2.C3A RHEB
Mean 51.2
Standard deviation 9.4
Values 58 45
[4]
HuH.7 RHEB
Mean 46.6
Standard deviation 5.3
Values 53 44 44
[5]
SNU475 RHEB
Mean 57.5
Standard deviation 1.9
Values 56 59
[6]
THLE RHEB
Mean 69.7
Standard deviation 5.7
Values 66 74
[7]
liver RHEB
Mean 44.9
Standard deviation 28
Values 18 25 77 59
[8]
ref_hepatocyte EIF4EBP1
Mean 48.7
Standard deviation 38
Values 90 20 87 11 35
[9]
HepG2 EIF4EBP1
Mean 54.1
Standard deviation 26
Values 36 72
[10]
HepG2.C3A EIF4EBP1
Mean 38.6
Standard deviation 15
Values 28 49
[11]
HuH.7 EIF4EBP1
Mean 56.5
Standard deviation 22
Values 73 32 64
[12]
SNU475 EIF4EBP1
Mean 9.08
Standard deviation 1.3
Values 10 8.2
[13]
THLE EIF4EBP1
Mean 29.8
Standard deviation 5
Values 33 26
[14]
liver EIF4EBP1
Mean 22.9
Standard deviation 28
Values 4.4 3.1 62 22
[15]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[16]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[17]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[18]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[19]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[20]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[21]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[22]
ref_hepatocyte PRKAG1
Mean 18.2
Standard deviation 5.6
Values 21 14 20 11 25
[23]
HepG2 PRKAG1
Mean 15.1
Standard deviation 4.3
Values 18 12
[24]
HepG2.C3A PRKAG1
Mean 19.4
Standard deviation 1.6
Values 21 18
[25]
HuH.7 PRKAG1
Mean 20.2
Standard deviation 3.3
Values 19 24 18
[26]
SNU475 PRKAG1
Mean 26.4
Standard deviation 2
Values 25 28
[27]
THLE PRKAG1
Mean 24.2
Standard deviation 2.7
Values 22 26
[28]
liver PRKAG1
Mean 8.25
Standard deviation 1.9
Values 5.8 9 7.9 10
[29]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 9.3 4.6 3.3 32 23
[30]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 57 42
[31]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 72 47
[32]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 71 70 86
[33]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 46 59
[34]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[35]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 16 21 14 18
[36]
ref_hepatocyte PRKAG2
Mean 13.4
Standard deviation 15
Values 22 4.1 4.6 0.42 36
[37]
HepG2 PRKAG2
Mean 1.78
Standard deviation 0.11
Values 1.9 1.7
[38]
HepG2.C3A PRKAG2
Mean 0.0463
Standard deviation 0.01
Values 0.054 0.039
[39]
HuH.7 PRKAG2
Mean 3.84
Standard deviation 0.36
Values 4.3 3.7 3.6
[40]
SNU475 PRKAG2
Mean 7.37
Standard deviation 0.53
Values 7.7 7
[41]
THLE PRKAG2
Mean 9.12
Standard deviation 0.1
Values 9.2 9
[42]
liver PRKAG2
Mean 13.7
Standard deviation 5.4
Values 8.1 10 19 18
[43]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 11 8.8 7.4 4 27
[44]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 12 14
[45]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 7.9 6
[46]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 5.6 2.4 3.6
[47]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[48]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[49]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 1.4 1.1 4.1 3.8
[50]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[51]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[52]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[53]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[54]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[55]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[56]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[57]
ref_hepatocyte AKT2
Mean 10.6
Standard deviation 2.8
Values 11 14 13 7.2 8.4
[58]
HepG2 AKT2
Mean 45.6
Standard deviation 3.3
Values 43 48
[59]
HepG2.C3A AKT2
Mean 49.1
Standard deviation 8.9
Values 43 55
[60]
HuH.7 AKT2
Mean 51.5
Standard deviation 9.8
Values 55 41 59
[61]
SNU475 AKT2
Mean 35.3
Standard deviation 5.9
Values 31 39
[62]
THLE AKT2
Mean 34.2
Standard deviation 3.5
Values 32 37
[63]
liver AKT2
Mean 33
Standard deviation 9.4
Values 45 36 24 27
[64]
ref_hepatocyte UBE3A
Mean 10.5
Standard deviation 5.2
Values 6.2 7.8 6.5 14 18
[65]
HepG2 UBE3A
Mean 18.9
Standard deviation 4.5
Values 22 16
[66]
HepG2.C3A UBE3A
Mean 29.5
Standard deviation 3.4
Values 32 27
[67]
HuH.7 UBE3A
Mean 28.7
Standard deviation 7
Values 23 36 27
[68]
SNU475 UBE3A
Mean 33.1
Standard deviation 0.13
Values 33 33
[69]
THLE UBE3A
Mean 34.5
Standard deviation 0.21
Values 34 35
[70]
liver UBE3A
Mean 34.7
Standard deviation 5.6
Values 37 41 34 27
[71]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 5.4 2.7 1.7 18 17
[72]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 16 12
[73]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 14 11
[74]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 36 30 40
[75]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 25 33
[76]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[77]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 14 16 33 19
[78]
ref_hepatocyte PRKAA1
Mean 8.04
Standard deviation 3.4
Values 6.1 14 7.2 5.4 7.6
[79]
HepG2 PRKAA1
Mean 16.8
Standard deviation 2.1
Values 18 15
[80]
HepG2.C3A PRKAA1
Mean 36.3
Standard deviation 5.5
Values 40 32
[81]
HuH.7 PRKAA1
Mean 99.5
Standard deviation 14
Values 84 1e+02 1.1e+02
[82]
SNU475 PRKAA1
Mean 40.7
Standard deviation 4.8
Values 37 44
[83]
THLE PRKAA1
Mean 55.1
Standard deviation 6.9
Values 60 50
[84]
liver PRKAA1
Mean 47.6
Standard deviation 7.3
Values 47 58 40 45
[85]
ref_hepatocyte PRKAB2
Mean 7.76
Standard deviation 2.5
Values 8.8 7.4 4.5 11 6.7
[86]
HepG2 PRKAB2
Mean 31.7
Standard deviation 10
Values 39 25
[87]
HepG2.C3A PRKAB2
Mean 64.2
Standard deviation 12
Values 56 73
[88]
HuH.7 PRKAB2
Mean 66.5
Standard deviation 35
Values 46 1.1e+02 47
[89]
SNU475 PRKAB2
Mean 29
Standard deviation 6.7
Values 24 34
[90]
THLE PRKAB2
Mean 15.9
Standard deviation 0.88
Values 17 15
[91]
liver PRKAB2
Mean 29.3
Standard deviation 1.5
Values 28 30 28 31
[92]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.2 14 8.1 4.1 7.4
[93]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 14 9.8
[94]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 13 9.6
[95]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 15 32 23
[96]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 35 80
[97]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[98]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 1.4e+02 1e+02 64 32
[99]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 5.2 11 7 4.2 5.9
[100]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 12 8.4
[101]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 21 26
[102]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[103]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 6.9 9.4
[104]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[105]
liver PTEN
Mean 52
Standard deviation 9.3
Values 53 55 61 39
[106]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 3.1 3.8 4.9 11 3.2
[107]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 41 44
[108]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 35 53
[109]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 64 55 75
[110]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 13 18
[111]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[112]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 6.9 6 7.6 3.8
[113]
ref_hepatocyte PRKAB1
Mean 4.81
Standard deviation 1.6
Values 4.2 6.9 5.3 2.5 5.1
[114]
HepG2 PRKAB1
Mean 17.4
Standard deviation 1
Values 17 18
[115]
HepG2.C3A PRKAB1
Mean 22.4
Standard deviation 1.5
Values 21 23
[116]
HuH.7 PRKAB1
Mean 11.9
Standard deviation 0.19
Values 12 12 12
[117]
SNU475 PRKAB1
Mean 8.43
Standard deviation 1.5
Values 7.4 9.5
[118]
THLE PRKAB1
Mean 10.2
Standard deviation 0.44
Values 9.9 10
[119]
liver PRKAB1
Mean 6.83
Standard deviation 3.2
Values 4 4.5 7.9 11
[120]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[121]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[122]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[123]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[124]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[125]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[126]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[127]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[128]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[129]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[130]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[131]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[132]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[133]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[134]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[135]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[136]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[137]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[138]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[139]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[140]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[141]
ref_hepatocyte TSC2
Mean 3.2
Standard deviation 0.13
Values 3.2 3.4 3.2 3.1 3.1
[142]
HepG2 TSC2
Mean 24.9
Standard deviation 3.4
Values 22 27
[143]
HepG2.C3A TSC2
Mean 16
Standard deviation 4.7
Values 13 19
[144]
HuH.7 TSC2
Mean 24.6
Standard deviation 4
Values 21 24 29
[145]
SNU475 TSC2
Mean 13.5
Standard deviation 5
Values 10 17
[146]
THLE TSC2
Mean 21.8
Standard deviation 1.7
Values 21 23
[147]
liver TSC2
Mean 19.2
Standard deviation 2.2
Values 22 19 17 18
[148]
ref_hepatocyte RPS6KB1
Mean 3.19
Standard deviation 1.6
Values 1.9 2.1 2 5.1 4.9
[149]
HepG2 RPS6KB1
Missing
[150]
HepG2.C3A RPS6KB1
Missing
[151]
HuH.7 RPS6KB1
Missing
[152]
SNU475 RPS6KB1
Missing
[153]
THLE RPS6KB1
Missing
[154]
liver RPS6KB1
Missing
[155]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 2.6 2.1 1.8 5.2 4.2
[156]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 18 15
[157]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 19 23
[158]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 20 23 24
[159]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 10 14
[160]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[161]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 11 15 6.4 7.9
[162]
ref_hepatocyte RPTOR
Mean 1.96
Standard deviation 0.72
Values 2.6 1.2 1.1 2.5 2.4
[163]
HepG2 RPTOR
Mean 36.8
Standard deviation 1
Values 38 36
[164]
HepG2.C3A RPTOR
Mean 19.3
Standard deviation 0.98
Values 19 20
[165]
HuH.7 RPTOR
Mean 19.8
Standard deviation 7.4
Values 17 14 28
[166]
SNU475 RPTOR
Mean 13
Standard deviation 0.49
Values 13 13
[167]
THLE RPTOR
Mean 17.1
Standard deviation 3.1
Values 15 19
[168]
liver RPTOR
Mean 14.1
Standard deviation 7.6
Values 21 20 7.5 7.6
[169]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 0.94 1.2 2.3 2.6
[170]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 4.3 2.1
[171]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 9.6 8
[172]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 7 12 10
[173]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 6.8 8.1
[174]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[175]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 13 15 6.1 6
[176]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 3.3 0.66 0.38 4.1 0.94
[177]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 13 18
[178]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 27 31
[179]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 1.6 2.3 2
[180]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 3.7 4.6
[181]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[182]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 5.1 3 2.4 2.6
[183]
ref_hepatocyte TSC1
Mean 1.81
Standard deviation 0.96
Values 2.1 1.1 0.7 3.1 2.1
[184]
HepG2 TSC1
Mean 14.8
Standard deviation 1.6
Values 16 14
[185]
HepG2.C3A TSC1
Mean 20.9
Standard deviation 3.3
Values 19 23
[186]
HuH.7 TSC1
Mean 22.2
Standard deviation 4.3
Values 18 26 22
[187]
SNU475 TSC1
Mean 13.9
Standard deviation 2.8
Values 12 16
[188]
THLE TSC1
Mean 18
Standard deviation 3.2
Values 16 20
[189]
liver TSC1
Mean 17.4
Standard deviation 1.8
Values 17 20 17 16
[190]
ref_hepatocyte NF1
Mean 1.76
Standard deviation 0.43
Values 1.7 1.5 1.3 1.9 2.4
[191]
HepG2 NF1
Mean 21.4
Standard deviation 7.6
Values 27 16
[192]
HepG2.C3A NF1
Mean 24
Standard deviation 0.77
Values 25 23
[193]
HuH.7 NF1
Mean 40.5
Standard deviation 13
Values 26 48 48
[194]
SNU475 NF1
Mean 50.6
Standard deviation 4.9
Values 47 54
[195]
THLE NF1
Mean 38.4
Standard deviation 0.9
Values 38 39
[196]
liver NF1
Mean 43.1
Standard deviation 30
Values 64 73 22 13
[197]
ref_hepatocyte HOMER1
Mean 0.981
Standard deviation 0.91
Values 1.2 0.15 0.095 2.3 1.2
[198]
HepG2 HOMER1
Mean 5.82
Standard deviation 1.7
Values 7.1 4.6
[199]
HepG2.C3A HOMER1
Mean 9.95
Standard deviation 3.3
Values 12 7.6
[200]
HuH.7 HOMER1
Mean 15.9
Standard deviation 2.9
Values 13 17 18
[201]
SNU475 HOMER1
Mean 5.18
Standard deviation 0.23
Values 5.3 5
[202]
THLE HOMER1
Mean 4.76
Standard deviation 0.59
Values 4.3 5.2
[203]
liver HOMER1
Mean 0.97
Standard deviation 0.44
Values 0.78 1.6 0.87 0.62
[204]
ref_hepatocyte SHANK3
Mean 0.765
Standard deviation 0.34
Values 1 0.76 1.1 0.76 0.22
[205]
HepG2 SHANK3
Mean 14.9
Standard deviation 2.9
Values 13 17
[206]
HepG2.C3A SHANK3
Mean 11.6
Standard deviation 4
Values 8.7 14
[207]
HuH.7 SHANK3
Mean 11.9
Standard deviation 4.2
Values 8.5 17 11
[208]
SNU475 SHANK3
Mean 2.89
Standard deviation 0.8
Values 2.3 3.5
[209]
THLE SHANK3
Mean 1.33
Standard deviation 0.27
Values 1.5 1.1
[210]
liver SHANK3
Mean 8.57
Standard deviation 6.4
Values 16 12 4.1 2.6
[211]
ref_hepatocyte PRKAA2
Mean 0.754
Standard deviation 0.84
Values 0.23 0.24 0.1 2 1.2
[212]
HepG2 PRKAA2
Mean 13.6
Standard deviation 4
Values 16 11
[213]
HepG2.C3A PRKAA2
Mean 16.6
Standard deviation 1.4
Values 18 16
[214]
HuH.7 PRKAA2
Mean 16.2
Standard deviation 6.6
Values 9.7 23 16
[215]
SNU475 PRKAA2
Mean 11.4
Standard deviation 0.77
Values 11 12
[216]
THLE PRKAA2
Mean 3.29
Standard deviation 0.6
Values 3.7 2.9
[217]
liver PRKAA2
Mean 3.87
Standard deviation 1.2
Values 5 4 4.3 2.2
[218]
ref_hepatocyte CAMK2B
Mean 0.643
Standard deviation 0.6
Values 0 1.3 0.9 0 1.1
[219]
HepG2 CAMK2B
Mean 0.245
Standard deviation 0.067
Values 0.2 0.29
[220]
HepG2.C3A CAMK2B
Mean 0.0871
Standard deviation 0.013
Values 0.097 0.078
[221]
HuH.7 CAMK2B
Mean 0.0107
Standard deviation 0.0051
Values 0.0094 0.0064 0.016
[222]
SNU475 CAMK2B
Mean 0.162
Standard deviation 0.072
Values 0.11 0.21
[223]
THLE CAMK2B
Mean 0.283
Standard deviation 0.15
Values 0.39 0.18
[224]
liver CAMK2B
Mean 2.02
Standard deviation 0.9
Values 1.2 2.2 1.5 3.2
[225]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.47 0.15 0.078 0.52 0.81
[226]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 4.7 1.2
[227]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 3.8 1.5
[228]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5 3.1 5.7
[229]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.8 6.5
[230]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[231]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 4 3.8 3.7 3.3
[232]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0.83 0.41 0.16 0 0.53
[233]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.13 0.34
[234]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.043 0.029
[235]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.028 0.09 0.049
[236]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 34 48
[237]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[238]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 9.4 12 2.8 2.3
[239]
ref_hepatocyte DLG4
Mean 0.259
Standard deviation 0.21
Values 0.16 0.51 0.45 0.17 0
[240]
HepG2 DLG4
Mean 3.93
Standard deviation 2.2
Values 2.3 5.5
[241]
HepG2.C3A DLG4
Mean 4.27
Standard deviation 0.27
Values 4.1 4.5
[242]
HuH.7 DLG4
Mean 1.73
Standard deviation 0.71
Values 1.3 2.5 1.3
[243]
SNU475 DLG4
Mean 1.85
Standard deviation 0.71
Values 2.4 1.3
[244]
THLE DLG4
Mean 9.6
Standard deviation 0.94
Values 10 8.9
[245]
liver DLG4
Mean 1.19
Standard deviation 1.3
Values 3 1.2 0.26 0.28
[246]
ref_hepatocyte SYNGAP1
Mean 0.133
Standard deviation 0.074
Values 0.16 0.15 0.22 0.12 0.018
[247]
HepG2 SYNGAP1
Mean 2.69
Standard deviation 0.51
Values 2.3 3
[248]
HepG2.C3A SYNGAP1
Mean 2.34
Standard deviation 0.047
Values 2.3 2.4
[249]
HuH.7 SYNGAP1
Mean 2.33
Standard deviation 0.42
Values 2.1 2.8 2.1
[250]
SNU475 SYNGAP1
Mean 7.21
Standard deviation 0.98
Values 6.5 7.9
[251]
THLE SYNGAP1
Mean 10.9
Standard deviation 3.2
Values 13 8.6
[252]
liver SYNGAP1
Mean 0.695
Standard deviation 0.34
Values 1 0.97 0.47 0.33
[253]
ref_hepatocyte ARC
Mean 0.127
Standard deviation 0.25
Values 0.58 0.057 0 0 0
[254]
HepG2 ARC
Mean 0.053
Standard deviation 0.01
Values 0.06 0.046
[255]
HepG2.C3A ARC
Mean 0.214
Standard deviation 0.15
Values 0.11 0.32
[256]
HuH.7 ARC
Mean 0.0109
Standard deviation 0.019
Values 0 0 0.033
[257]
SNU475 ARC
Mean 0.091
Standard deviation 0.12
Values 0.18 0.0046
[258]
THLE ARC
Mean 1.28
Standard deviation 0.35
Values 1 1.5
[259]
liver ARC
Mean 0.0158
Standard deviation 0.019
Values 0.04 0 0.024 0
[260]
ref_hepatocyte GRIN2D
Mean 0.0598
Standard deviation 0.13
Values 0 0 0 0.3 0
[261]
HepG2 GRIN2D
Mean 2.96
Standard deviation 2.4
Values 1.3 4.6
[262]
HepG2.C3A GRIN2D
Mean 2.45
Standard deviation 0.75
Values 1.9 3
[263]
HuH.7 GRIN2D
Mean 2.93
Standard deviation 0.45
Values 2.6 2.7 3.5
[264]
SNU475 GRIN2D
Mean 0.755
Standard deviation 0.44
Values 1.1 0.44
[265]
THLE GRIN2D
Mean 0.41
Standard deviation 0.031
Values 0.43 0.39
[266]
liver GRIN2D
Mean 0.0818
Standard deviation 0.083
Values 0.13 0.17 0.024 0
[267]
ref_hepatocyte BDNF
Mean 0.0532
Standard deviation 0.065
Values 0.095 0.024 0.15 0 0
[268]
HepG2 BDNF
Mean 0.0372
Standard deviation 0.0041
Values 0.034 0.04
[269]
HepG2.C3A BDNF
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[270]
HuH.7 BDNF
Mean 0.0177
Standard deviation 0.024
Values 0 0.045 0.0082
[271]
SNU475 BDNF
Mean 10.5
Standard deviation 1.7
Values 12 9.3
[272]
THLE BDNF
Mean 4.97
Standard deviation 1.1
Values 5.7 4.2
[273]
liver BDNF
Mean 0.324
Standard deviation 0.17
Values 0.3 0.57 0.19 0.23
[274]
ref_hepatocyte GRIN3A
Mean 0.0423
Standard deviation 0.065
Values 0 0.065 0.15 0 0
[275]
HepG2 GRIN3A
Mean 0.0415
Standard deviation 0.002
Values 0.043 0.04
[276]
HepG2.C3A GRIN3A
Mean 0.145
Standard deviation 0.084
Values 0.086 0.2
[277]
HuH.7 GRIN3A
Mean 0.158
Standard deviation 0.06
Values 0.094 0.17 0.21
[278]
SNU475 GRIN3A
Mean 0.215
Standard deviation 0.017
Values 0.2 0.23
[279]
THLE GRIN3A
Mean 0.115
Standard deviation 0.0047
Values 0.12 0.11
[280]
liver GRIN3A
Mean 0.717
Standard deviation 0.47
Values 1 1.2 0.33 0.31
[281]
ref_hepatocyte CAMK4
Mean 0.0277
Standard deviation 0.046
Values 0 0.033 0 0 0.11
[282]
HepG2 CAMK4
Mean 0
Standard deviation 0
Values 0 0
[283]
HepG2.C3A CAMK4
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[284]
HuH.7 CAMK4
Mean 0.00975
Standard deviation 0.0086
Values 0 0.013 0.016
[285]
SNU475 CAMK4
Mean 0.139
Standard deviation 0.098
Values 0.21 0.07
[286]
THLE CAMK4
Mean 0.651
Standard deviation 0.27
Values 0.46 0.84
[287]
liver CAMK4
Mean 0.748
Standard deviation 0.17
Values 0.52 0.8 0.75 0.92
[288]
ref_hepatocyte GRIN3B
Mean 0.0218
Standard deviation 0.049
Values 0 0 0 0 0.11
[289]
HepG2 GRIN3B
Mean 0.746
Standard deviation 0.75
Values 0.21 1.3
[290]
HepG2.C3A GRIN3B
Mean 0.273
Standard deviation 0.082
Values 0.21 0.33
[291]
HuH.7 GRIN3B
Mean 0.399
Standard deviation 0.28
Values 0.28 0.72 0.2
[292]
SNU475 GRIN3B
Mean 0.0485
Standard deviation 0.003
Values 0.051 0.046
[293]
THLE GRIN3B
Mean 0.401
Standard deviation 0.31
Values 0.62 0.18
[294]
liver GRIN3B
Mean 0.143
Standard deviation 0.18
Values 0.37 0.2 0 0
[295]
ref_hepatocyte GRIN2B
Mean 0.0213
Standard deviation 0.039
Values 0 0.089 0.017 0 0
[296]
HepG2 GRIN2B
Mean 0.00858
Standard deviation 0.012
Values 0.017 0
[297]
HepG2.C3A GRIN2B
Mean 0
Standard deviation 0
Values 0 0
[298]
HuH.7 GRIN2B
Mean 0
Standard deviation 0
Values 0 0 0
[299]
SNU475 GRIN2B
Mean 0.0833
Standard deviation 0.046
Values 0.051 0.12
[300]
THLE GRIN2B
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[301]
liver GRIN2B
Mean 0.11
Standard deviation 0.05
Values 0.17 0.1 0.12 0.051
[302]
ref_hepatocyte PRKAG3
Mean 0.013
Standard deviation 0.029
Values 0 0.065 0 0 0
[303]
HepG2 PRKAG3
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[304]
HepG2.C3A PRKAG3
Mean 0
Standard deviation 0
Values 0 0
[305]
HuH.7 PRKAG3
Mean 0.00586
Standard deviation 0.0051
Values 0.0094 0 0.0082
[306]
SNU475 PRKAG3
Mean 0.0118
Standard deviation 0.0095
Values 0.0051 0.019
[307]
THLE PRKAG3
Mean 0
Standard deviation 0
Values 0 0
[308]
liver PRKAG3
Mean 0.161
Standard deviation 0.27
Values 0.57 0.029 0.047 0
[309]
ref_hepatocyte GRIN2C
Mean 0.00517
Standard deviation 0.012
Values 0 0 0.026 0 0
[310]
HepG2 GRIN2C
Mean 0.137
Standard deviation 0.097
Values 0.069 0.21
[311]
HepG2.C3A GRIN2C
Mean 0.385
Standard deviation 0.077
Values 0.44 0.33
[312]
HuH.7 GRIN2C
Mean 0.14
Standard deviation 0.025
Values 0.17 0.13 0.12
[313]
SNU475 GRIN2C
Mean 0.106
Standard deviation 0.007
Values 0.1 0.11
[314]
THLE GRIN2C
Mean 0.185
Standard deviation 0.15
Values 0.29 0.08
[315]
liver GRIN2C
Mean 0.113
Standard deviation 0.079
Values 0.2 0.16 0.071 0.026
[316]
ref_hepatocyte CACNA1C
Mean 0.00217
Standard deviation 0.0049
Values 0.011 0 0 0 0
[317]
HepG2 CACNA1C
Mean 0.127
Standard deviation 0.16
Values 0.013 0.24
[318]
HepG2.C3A CACNA1C
Mean 0.0199
Standard deviation 0.013
Values 0.011 0.029
[319]
HuH.7 CACNA1C
Mean 0.139
Standard deviation 0.11
Values 0.16 0.019 0.24
[320]
SNU475 CACNA1C
Mean 0.21
Standard deviation 0.15
Values 0.31 0.11
[321]
THLE CACNA1C
Mean 1.11
Standard deviation 0.48
Values 1.4 0.77
[322]
liver CACNA1C
Mean 0.978
Standard deviation 0.97
Values 2.2 1.3 0.19 0.23
[323]
ref_hepatocyte GRIN2A
Mean 0.00172
Standard deviation 0.0039
Values 0 0 0.0086 0 0
[324]
HepG2 GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[325]
HepG2.C3A GRIN2A
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 GRIN2A
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[327]
SNU475 GRIN2A
Mean 1.69
Standard deviation 0.46
Values 2 1.4
[328]
THLE GRIN2A
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[329]
liver GRIN2A
Mean 0.641
Standard deviation 0.48
Values 1.3 0.74 0.28 0.26
[330]
ref_hepatocyte GRM1
Mean 0.00109
Standard deviation 0.0024
Values 0.0054 0 0 0 0
[331]
HepG2 GRM1
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[332]
HepG2.C3A GRM1
Mean 0
Standard deviation 0
Values 0 0
[333]
HuH.7 GRM1
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[334]
SNU475 GRM1
Mean 0.0949
Standard deviation 0.063
Values 0.051 0.14
[335]
THLE GRM1
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[336]
liver GRM1
Mean 0.0135
Standard deviation 0.019
Values 0.04 0.014 0 0
[337]
ref_hepatocyte MIR5004
Missing
[338]
HepG2 MIR5004
Mean 0
Standard deviation 0
Values 0 0
[339]
HepG2.C3A MIR5004
Mean 0
Standard deviation 0
Values 0 0
[340]
HuH.7 MIR5004
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[341]
SNU475 MIR5004
Mean 0
Standard deviation 0
Values 0 0
[342]
THLE MIR5004
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[343]
liver MIR5004
Mean 0
Standard deviation 0
Values 0 0 0 0
[344]
ref_hepatocyte GRIN1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[345]
HepG2 GRIN1
Mean 0.68
Standard deviation 0.6
Values 0.25 1.1
[346]
HepG2.C3A GRIN1
Mean 0.154
Standard deviation 0.11
Values 0.075 0.23
[347]
HuH.7 GRIN1
Mean 0.0602
Standard deviation 0.028
Values 0.028 0.071 0.082
[348]
SNU475 GRIN1
Mean 0.0414
Standard deviation 0.006
Values 0.046 0.037
[349]
THLE GRIN1
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[350]
liver GRIN1
Mean 0
Standard deviation 0
Values 0 0 0 0
[351]
ref_hepatocyte NTRK2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[352]
HepG2 NTRK2
Mean 0.0201
Standard deviation 0.028
Values 0 0.04
[353]
HepG2.C3A NTRK2
Mean 0
Standard deviation 0
Values 0 0
[354]
HuH.7 NTRK2
Mean 0
Standard deviation 0
Values 0 0 0
[355]
SNU475 NTRK2
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[356]
THLE NTRK2
Mean 0
Standard deviation 0
Values 0 0
[357]
liver NTRK2
Mean 1.46
Standard deviation 0.52
Values 2 1.2 0.89 1.8