WP_STING_PATHWAY_IN_KAWASAKILIKE_DISEASE_AND_COVID19 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 NFKBIA NF-kappa-B inhibitor alpha [1] -0.55[2] -2.26[3] -2.39[4] -2.59[5] -1.24[6] -0.70[7]
2 GSDMD Gasdermin-D [8] -1.41[9] -0.52[10] -0.93[11] -0.34[12] -1.93[13] -0.21[14]
3 IKBKG NF-kappa-B essential modulator [15] -0.38[16] -0.16[17] -2.15[18] 0.08[19] -1.66[20] -0.16[21]
4 RELA Transcription factor p65 [22] 0.64[23] 0.22[24] 0.60[25] 0.87[26] 0.25[27] -0.44[28]
5 IRF3 Interferon regulatory factor 3 [29] 0.81[30] 1.06[31] 2.03[32] 1.28[33] 0.35[34] -0.74[35]
6 TBK1 Serine/threonine-protein kinase TBK1 [36] -0.13[37] 1.63[38] 1.03[39] 1.42[40] 0.98[41] 0.91[42]
7 NFKB1 Nuclear factor NF-kappa-B p105 subunit [43] 1.18[44] 0.93[45] 0.98[46] 0.68[47] 1.06[48] 0.89[49]
8 NFKBIE NF-kappa-B inhibitor epsilon [50] 0.55[51] 1.55[52] -0.06[53] 0.15[54] 0.08[55] -0.83[56]
9 CHUK Inhibitor of nuclear factor kappa-B kinase subunit alpha [57] 1.41[58] 2.71[59] 2.92[60] 1.58[61] 1.86[62] 1.96[63]
10 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [64] 1.03[65] 1.17[66] 1.52[67] 1.19[68] 0.75[69] 1.62[70]
11 IL1B Interleukin-1 beta [71] -8.19[72] -7.98[73] -3.40[74] -2.66[75] 2.40[76] -4.76[77]
12 F3 Tissue factor [78] -0.03[79] -0.25[80] -0.20[81] 0.58[82] 3.41[83] -1.45[84]
13 NLRX1 NLR family member X1 [85] 2.36[86] 1.79[87] 0.75[88] 2.15[89] 0.93[90] 1.59[91]
14 FCGR2A Low affinity immunoglobulin gamma Fc region receptor II-a [92] -5.87[93] [94] -2.83[95] -1.63[96] -4.66[97] 1.64[98]
15 IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon [99] 2.23[100] 2.18[101] 1.32[102] 3.49[103] 2.51[104] 0.21[105]
16 REL Proto-oncogene c-Rel [106] -0.01[107] 1.84[108] 2.02[109] 1.07[110] 0.70[111] 2.79[112]
17 ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 [113] 3.64[114] 3.61[115] 5.02[116] 3.78[117] 4.12[118] 5.09[119]
18 NLRP3 NACHT, LRR and PYD domains-containing protein 3 [120] -3.13[121] -0.81[122] -2.36[123] -0.46[124] 1.50[125] 2.03[126]
19 IFNB1 Interferon beta [127] [128] [129] [130] [131] [132] [133]
20 STING1 [134] [135] [136] [137] [138] [139] [140]
21 FCGR2C Low affinity immunoglobulin gamma Fc region receptor II-c [141] [142] [143] [144] [145] [146] [147]
22 CGAS [148] [149] [150] [151] [152] [153] [154]
[1]
ref_hepatocyte NFKBIA
Mean 84.3
Standard deviation 48
Values 1.6e+02 40 90 83 48
[2]
HepG2 NFKBIA
Mean 89.6
Standard deviation 1.2
Values 90 89
[3]
HepG2.C3A NFKBIA
Mean 23
Standard deviation 1.2
Values 22 24
[4]
HuH.7 NFKBIA
Mean 17
Standard deviation 7.2
Values 15 25 11
[5]
SNU475 NFKBIA
Mean 13.5
Standard deviation 0.67
Values 14 13
[6]
THLE NFKBIA
Mean 55.8
Standard deviation 6.4
Values 51 60
[7]
liver NFKBIA
Mean 54.5
Standard deviation 46
Values 24 19 1.2e+02 55
[8]
ref_hepatocyte GSDMD
Mean 24
Standard deviation 21
Values 14 36 55 5.5 9.4
[9]
HepG2 GSDMD
Mean 14
Standard deviation 2.3
Values 16 12
[10]
HepG2.C3A GSDMD
Mean 22
Standard deviation 2.9
Values 20 24
[11]
HuH.7 GSDMD
Mean 13.3
Standard deviation 4.2
Values 17 8.8 14
[12]
SNU475 GSDMD
Mean 18.4
Standard deviation 3.2
Values 16 21
[13]
THLE GSDMD
Mean 9.83
Standard deviation 1.7
Values 11 8.6
[14]
liver GSDMD
Mean 21.7
Standard deviation 5.3
Values 23 16 29 19
[15]
ref_hepatocyte IKBKG
Mean 22.7
Standard deviation 14
Values 37 10 24 7.4 36
[16]
HepG2 IKBKG
Mean 27.1
Standard deviation 5.7
Values 23 31
[17]
HepG2.C3A IKBKG
Mean 26.7
Standard deviation 4
Values 24 30
[18]
HuH.7 IKBKG
Mean 5.4
Standard deviation 1.3
Values 6.7 4.1 5.4
[19]
SNU475 IKBKG
Mean 23.2
Standard deviation 3.5
Values 26 21
[20]
THLE IKBKG
Mean 11.2
Standard deviation 1
Values 10 12
[21]
liver IKBKG
Mean 21.3
Standard deviation 6.6
Values 13 22 20 29
[22]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 35 8.1 15 9.8 12
[23]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 35 42
[24]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 20 29
[25]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 23 25 29
[26]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[27]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[28]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 5.7 4.1 19 20
[29]
ref_hepatocyte IRF3
Mean 10
Standard deviation 4.1
Values 13 10 15 7.1 4.7
[30]
HepG2 IRF3
Mean 27.2
Standard deviation 6.6
Values 23 32
[31]
HepG2.C3A IRF3
Mean 27.3
Standard deviation 1.4
Values 26 28
[32]
HuH.7 IRF3
Mean 43.3
Standard deviation 14
Values 54 28 47
[33]
SNU475 IRF3
Mean 23.5
Standard deviation 4.3
Values 27 20
[34]
THLE IRF3
Mean 19.9
Standard deviation 0.46
Values 20 20
[35]
liver IRF3
Mean 6.27
Standard deviation 2.8
Values 4 3.7 8.8 8.7
[36]
ref_hepatocyte TBK1
Mean 6.94
Standard deviation 1.7
Values 8.4 5.2 5 7.8 8.4
[37]
HepG2 TBK1
Mean 9.87
Standard deviation 3.8
Values 13 7.2
[38]
HepG2.C3A TBK1
Mean 28.1
Standard deviation 7.6
Values 33 23
[39]
HuH.7 TBK1
Mean 14.9
Standard deviation 0.71
Values 15 16 14
[40]
SNU475 TBK1
Mean 17.9
Standard deviation 1.5
Values 17 19
[41]
THLE TBK1
Mean 21.3
Standard deviation 2.3
Values 23 20
[42]
liver TBK1
Mean 13.7
Standard deviation 2.9
Values 10 15 13 17
[43]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[44]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[45]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[46]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[47]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[48]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[49]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[50]
ref_hepatocyte NFKBIE
Mean 4.06
Standard deviation 3
Values 7.5 1.7 2.2 1.7 7.2
[51]
HepG2 NFKBIE
Mean 9.22
Standard deviation 1.3
Values 8.3 10
[52]
HepG2.C3A NFKBIE
Mean 15.6
Standard deviation 4.6
Values 12 19
[53]
HuH.7 NFKBIE
Mean 4.1
Standard deviation 1
Values 4 5.2 3.1
[54]
SNU475 NFKBIE
Mean 4.34
Standard deviation 0.92
Values 5 3.7
[55]
THLE NFKBIE
Mean 6.68
Standard deviation 1.2
Values 5.8 7.6
[56]
liver NFKBIE
Mean 2.4
Standard deviation 0.62
Values 1.9 1.8 2.8 3.1
[57]
ref_hepatocyte CHUK
Mean 3.93
Standard deviation 1.2
Values 2.3 4.1 3.4 4.2 5.7
[58]
HepG2 CHUK
Mean 16.2
Standard deviation 6.4
Values 21 12
[59]
HepG2.C3A CHUK
Mean 33.6
Standard deviation 13
Values 43 25
[60]
HuH.7 CHUK
Mean 31.4
Standard deviation 3.3
Values 32 28 34
[61]
SNU475 CHUK
Mean 11.3
Standard deviation 1.1
Values 12 11
[62]
THLE CHUK
Mean 22.3
Standard deviation 0.15
Values 22 22
[63]
liver CHUK
Mean 16
Standard deviation 3.3
Values 15 21 13 15
[64]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[65]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[66]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[67]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[68]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[69]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[70]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[71]
ref_hepatocyte IL1B
Mean 3.09
Standard deviation 5.4
Values 13 0.76 2 0 0.08
[72]
HepG2 IL1B
Mean 0.0165
Standard deviation 0.017
Values 0.0043 0.029
[73]
HepG2.C3A IL1B
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[74]
HuH.7 IL1B
Mean 0.309
Standard deviation 0.06
Values 0.3 0.37 0.25
[75]
SNU475 IL1B
Mean 0.472
Standard deviation 0.21
Values 0.62 0.32
[76]
THLE IL1B
Mean 25.4
Standard deviation 8.5
Values 31 19
[77]
liver IL1B
Mean 0.12
Standard deviation 0.051
Values 0.17 0.11 0.14 0.051
[78]
ref_hepatocyte F3
Mean 2.57
Standard deviation 4.1
Values 0.35 0.42 0.4 9.9 1.8
[79]
HepG2 F3
Mean 3.92
Standard deviation 0.27
Values 4.1 3.7
[80]
HepG2.C3A F3
Mean 2.83
Standard deviation 0.16
Values 2.9 2.7
[81]
HuH.7 F3
Mean 2.35
Standard deviation 0.4
Values 2.6 1.9 2.6
[82]
SNU475 F3
Mean 3.7
Standard deviation 0.83
Values 4.3 3.1
[83]
THLE F3
Mean 42.4
Standard deviation 12
Values 34 51
[84]
liver F3
Mean 0.982
Standard deviation 0.29
Values 1.1 0.6 1.3 0.98
[85]
ref_hepatocyte NLRX1
Mean 1.88
Standard deviation 0.96
Values 1.5 3 2.7 1.5 0.69
[86]
HepG2 NLRX1
Mean 15
Standard deviation 1.9
Values 14 16
[87]
HepG2.C3A NLRX1
Mean 8.53
Standard deviation 1.2
Values 7.7 9.4
[88]
HuH.7 NLRX1
Mean 3.33
Standard deviation 0.79
Values 3.8 2.4 3.8
[89]
SNU475 NLRX1
Mean 8.04
Standard deviation 3.2
Values 5.8 10
[90]
THLE NLRX1
Mean 5.57
Standard deviation 0.21
Values 5.7 5.4
[91]
liver NLRX1
Mean 5.91
Standard deviation 0.39
Values 6.2 5.4 6.2 5.7
[92]
ref_hepatocyte FCGR2A
Mean 0.941
Standard deviation 1
Values 0.88 2.6 1.2 0 0.096
[93]
HepG2 FCGR2A
Mean 0.0251
Standard deviation 0.0051
Values 0.021 0.029
[94]
HepG2.C3A FCGR2A
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 FCGR2A
Mean 0.14
Standard deviation 0.049
Values 0.19 0.14 0.09
[96]
SNU475 FCGR2A
Mean 0.293
Standard deviation 0.0081
Values 0.3 0.29
[97]
THLE FCGR2A
Mean 0.0579
Standard deviation 0.023
Values 0.041 0.074
[98]
liver FCGR2A
Mean 3.07
Standard deviation 0.92
Values 3.3 3.1 1.8 4.1
[99]
ref_hepatocyte IKBKE
Mean 0.818
Standard deviation 0.8
Values 0.36 0.39 0.25 0.91 2.2
[100]
HepG2 IKBKE
Mean 5.94
Standard deviation 0.2
Values 6.1 5.8
[101]
HepG2.C3A IKBKE
Mean 4.84
Standard deviation 0.7
Values 5.3 4.3
[102]
HuH.7 IKBKE
Mean 2.16
Standard deviation 0.28
Values 2.3 1.8 2.3
[103]
SNU475 IKBKE
Mean 8.87
Standard deviation 0.19
Values 9 8.7
[104]
THLE IKBKE
Mean 7.27
Standard deviation 2.9
Values 5.2 9.3
[105]
liver IKBKE
Mean 0.988
Standard deviation 0.21
Values 0.69 0.98 1.2 1.1
[106]
ref_hepatocyte REL
Mean 0.479
Standard deviation 0.49
Values 0.1 0.24 0.23 1.3 0.51
[107]
HepG2 REL
Mean 0.741
Standard deviation 0.46
Values 1.1 0.42
[108]
HepG2.C3A REL
Mean 2.24
Standard deviation 0.8
Values 2.8 1.7
[109]
HuH.7 REL
Mean 2.05
Standard deviation 1.2
Values 0.74 3 2.4
[110]
SNU475 REL
Mean 0.975
Standard deviation 0.12
Values 1.1 0.89
[111]
THLE REL
Mean 1.22
Standard deviation 0.23
Values 1.1 1.4
[112]
liver REL
Mean 3.46
Standard deviation 0.82
Values 4.2 4.1 2.8 2.7
[113]
ref_hepatocyte ITPR1
Mean 0.398
Standard deviation 0.44
Values 0.1 0.25 0.2 1.2 0.25
[114]
HepG2 ITPR1
Mean 7.73
Standard deviation 1.3
Values 6.8 8.7
[115]
HepG2.C3A ITPR1
Mean 6.36
Standard deviation 0.83
Values 5.8 7
[116]
HuH.7 ITPR1
Mean 13.6
Standard deviation 3.5
Values 9.6 16 15
[117]
SNU475 ITPR1
Mean 5.27
Standard deviation 3.4
Values 7.7 2.8
[118]
THLE ITPR1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[119]
liver ITPR1
Mean 14.2
Standard deviation 12
Values 29 20 4.3 3.8
[120]
ref_hepatocyte NLRP3
Mean 0.117
Standard deviation 0.12
Values 0 0.19 0.28 0 0.11
[121]
HepG2 NLRP3
Mean 0.0207
Standard deviation 0.013
Values 0.03 0.011
[122]
HepG2.C3A NLRP3
Mean 0.0871
Standard deviation 0.013
Values 0.097 0.078
[123]
HuH.7 NLRP3
Mean 0.024
Standard deviation 0.036
Values 0.066 0.0064 0
[124]
SNU475 NLRP3
Mean 0.0819
Standard deviation 0.063
Values 0.13 0.037
[125]
THLE NLRP3
Mean 0.513
Standard deviation 0.15
Values 0.62 0.4
[126]
liver NLRP3
Mean 0.499
Standard deviation 0.28
Values 0.58 0.84 0.19 0.39
[127]
ref_hepatocyte IFNB1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 IFNB1
Missing
[129]
HepG2.C3A IFNB1
Missing
[130]
HuH.7 IFNB1
Missing
[131]
SNU475 IFNB1
Missing
[132]
THLE IFNB1
Missing
[133]
liver IFNB1
Missing
[134]
ref_hepatocyte STING1
Missing
[135]
HepG2 STING1
Missing
[136]
HepG2.C3A STING1
Missing
[137]
HuH.7 STING1
Missing
[138]
SNU475 STING1
Missing
[139]
THLE STING1
Missing
[140]
liver STING1
Missing
[141]
ref_hepatocyte FCGR2C
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 FCGR2C
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A FCGR2C
Mean 0.0312
Standard deviation 0.017
Values 0.043 0.019
[144]
HuH.7 FCGR2C
Mean 0.0213
Standard deviation 0.0061
Values 0.028 0.019 0.016
[145]
SNU475 FCGR2C
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE FCGR2C
Mean 0
Standard deviation 0
Values 0 0
[147]
liver FCGR2C
Mean 0.315
Standard deviation 0.3
Values 0.34 0.71 0.024 0.18
[148]
ref_hepatocyte CGAS
Missing
[149]
HepG2 CGAS
Missing
[150]
HepG2.C3A CGAS
Missing
[151]
HuH.7 CGAS
Missing
[152]
SNU475 CGAS
Missing
[153]
THLE CGAS
Missing
[154]
liver CGAS
Missing