WP_SOMATROPH_AXIS_GH_AND_ITS_RELATIONSHIP_TO_DIETARY_RESTRICTION_AND_AGING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AKT1 RAC-alpha serine/threonine-protein kinase [1] -0.74[2] -1.20[3] -1.72[4] -0.82[5] -1.04[6] -1.54[7]
2 PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN -1.36[8] -0.19[9] 0.57[10] -1.33[11] -0.33[12] 1.18[13]
3 MTOR Serine/threonine-protein kinase mTOR [14] 1.71[15] 2.50[16] 2.63[17] 1.92[18] 1.75[19] 2.15[20]
4 SIRT1 NAD-dependent protein deacetylase sirtuin-1 [21] -0.33[22] 0.55[23] 0.67[24] 0.80[25] 0.79[26] 0.04[27]
5 FOXO1 Forkhead box protein O1 [28] 0.87[29] 0.31[30] 1.01[31] 0.41[32] 2.18[33] 1.79[34]
6 IGF1R Insulin-like growth factor 1 receptor [35] 3.92[36] 3.00[37] 2.24[38] 3.71[39] 3.00[40] 0.79[41]
[1]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[2]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[3]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[4]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[5]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[6]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[7]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[8]
ref_hepatocyte PTEN
Mean 6.57
Standard deviation 2.4
Values 5.2 11 7 4.2 5.9
[9]
HepG2 PTEN
Mean 9.98
Standard deviation 2.3
Values 12 8.4
[10]
HepG2.C3A PTEN
Mean 23.3
Standard deviation 3.3
Values 21 26
[11]
HuH.7 PTEN
Mean 25.7
Standard deviation 12
Values 19 39 19
[12]
SNU475 PTEN
Mean 8.16
Standard deviation 1.8
Values 6.9 9.4
[13]
THLE PTEN
Mean 21.8
Standard deviation 0.98
Values 22 21
[14]
liver PTEN
Mean 52
Standard deviation 9.3
Values 53 55 61 39
[15]
ref_hepatocyte MTOR
Mean 3.34
Standard deviation 0.62
Values 4.3 3.2 3.5 2.6 3.1
[16]
HepG2 MTOR
Mean 42.7
Standard deviation 6.3
Values 47 38
[17]
HepG2.C3A MTOR
Mean 76.8
Standard deviation 17
Values 65 89
[18]
HuH.7 MTOR
Mean 54.5
Standard deviation 17
Values 41 50 73
[19]
SNU475 MTOR
Mean 39.4
Standard deviation 0.66
Values 40 39
[20]
THLE MTOR
Mean 46.6
Standard deviation 4.9
Values 43 50
[21]
liver MTOR
Mean 51.8
Standard deviation 18
Values 62 72 34 39
[22]
ref_hepatocyte SIRT1
Mean 1.83
Standard deviation 0.67
Values 1.2 2 1.4 2.9 1.6
[23]
HepG2 SIRT1
Mean 5.71
Standard deviation 1.4
Values 6.7 4.7
[24]
HepG2.C3A SIRT1
Mean 10.9
Standard deviation 1
Values 12 10
[25]
HuH.7 SIRT1
Mean 7.67
Standard deviation 1.5
Values 6.3 9.3 7.5
[26]
SNU475 SIRT1
Mean 9.92
Standard deviation 1.6
Values 11 8.8
[27]
THLE SIRT1
Mean 13.2
Standard deviation 0.39
Values 13 13
[28]
liver SIRT1
Mean 6.57
Standard deviation 1.6
Values 7.7 6.2 7.9 4.4
[29]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 2 2.6 1.9 0.71 1.7
[30]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 14 11
[31]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 7.9 10
[32]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 7.6 10 10
[33]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 6 8.6
[34]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[35]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 29 19 25 13
[36]
ref_hepatocyte IGF1R
Mean 0.745
Standard deviation 1.4
Values 0.29 0.065 0.043 3.3 0.021
[37]
HepG2 IGF1R
Mean 44
Standard deviation 16
Values 33 55
[38]
HepG2.C3A IGF1R
Mean 24.3
Standard deviation 6.5
Values 20 29
[39]
HuH.7 IGF1R
Mean 9.29
Standard deviation 2.1
Values 8.8 7.5 12
[40]
SNU475 IGF1R
Mean 30.3
Standard deviation 1.7
Values 29 32
[41]
THLE IGF1R
Mean 24.8
Standard deviation 4.5
Values 22 28
[42]
liver IGF1R
Mean 4.51
Standard deviation 2.6
Values 7.6 5.8 2.4 2.2