WP_SMC1SMC3_ROLE_IN_DNA_DAMAGE_CORNELIA_DE_LANGE_SYNDROME Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAD21 Double-strand-break repair protein rad21 homolog [1] -0.36[2] -0.17[3] -0.30[4] 0.09[5] -0.38[6] -1.07[7]
2 SMC3 Structural maintenance of chromosomes protein 3 [8] -1.97[9] -0.51[10] -0.28[11] -1.56[12] -1.22[13] -1.39[14]
3 NBN Nibrin [15] -1.22[16] -1.23[17] -1.71[18] -0.47[19] -1.44[20] -0.17[21]
4 SMC1A Structural maintenance of chromosomes protein 1A [22] 1.30[23] -0.03[24] 0.74[25] 1.04[26] 1.79[27] 1.00[28]
5 RAD50 DNA repair protein RAD50 [29] -0.65[30] 0.29[31] -0.79[32] -0.71[33] -0.31[34] 0.76[35]
6 PAXIP1 PAX-interacting protein 1 [36] 0.15[37] -0.98[38] -0.73[39] -1.43[40] -1.35[41] -1.16[42]
7 MDC1 Mediator of DNA damage checkpoint protein 1 [43] 1.69[44] 0.90[45] 1.00[46] 0.92[47] 0.75[48] 0.01[49]
8 BRCA1 Breast cancer type 1 susceptibility protein [50] 0.87[51] 0.93[52] 1.08[53] 0.17[54] 0.60[55] 0.23[56]
9 ATM Serine-protein kinase ATM [57] 2.23[58] 2.64[59] 2.13[60] 2.18[61] 1.57[62] 3.54[63]
10 RAD18 E3 ubiquitin-protein ligase RAD18 [64] 0.35[65] 0.35[66] 1.30[67] 0.39[68] 0.87[69] -0.44[70]
11 MIR3610 [71] [72] [73] [74] [75] [76] [77]
12 MRE11 Double-strand break repair protein MRE11 [78] [79] [80] [81] [82] [83] [84]
[1]
ref_hepatocyte RAD21
Mean 17.4
Standard deviation 8
Values 11 14 11 21 30
[2]
HepG2 RAD21
Mean 52
Standard deviation 19
Values 65 39
[3]
HepG2.C3A RAD21
Mean 121
Standard deviation 20
Values 1.4e+02 1.1e+02
[4]
HuH.7 RAD21
Mean 124
Standard deviation 2.7
Values 1.2e+02 1.3e+02 1.2e+02
[5]
SNU475 RAD21
Mean 133
Standard deviation 0.012
Values 1.3e+02 1.3e+02
[6]
THLE RAD21
Mean 115
Standard deviation 6.3
Values 1.1e+02 1.2e+02
[7]
liver RAD21
Mean 32
Standard deviation 6.7
Values 24 35 39 31
[8]
ref_hepatocyte SMC3
Mean 10.7
Standard deviation 7.5
Values 6.9 4.5 4.5 18 19
[9]
HepG2 SMC3
Mean 10.5
Standard deviation 3.1
Values 13 8.3
[10]
HepG2.C3A SMC3
Mean 58.7
Standard deviation 10
Values 66 51
[11]
HuH.7 SMC3
Mean 77.7
Standard deviation 3.5
Values 74 77 81
[12]
SNU475 SMC3
Mean 26.1
Standard deviation 8.4
Values 32 20
[13]
THLE SMC3
Mean 39.3
Standard deviation 13
Values 49 30
[14]
liver SMC3
Mean 15.8
Standard deviation 4.9
Values 11 13 22 16
[15]
ref_hepatocyte NBN
Mean 5.99
Standard deviation 3.6
Values 3.9 4.3 2.7 7.6 11
[16]
HepG2 NBN
Mean 9.9
Standard deviation 6.3
Values 14 5.4
[17]
HepG2.C3A NBN
Mean 20
Standard deviation 9.1
Values 26 14
[18]
HuH.7 NBN
Mean 16.2
Standard deviation 4.2
Values 17 12 20
[19]
SNU475 NBN
Mean 31.2
Standard deviation 0.96
Values 32 30
[20]
THLE NBN
Mean 19
Standard deviation 0.88
Values 20 18
[21]
liver NBN
Mean 20.5
Standard deviation 4.2
Values 16 24 19 24
[22]
ref_hepatocyte SMC1A
Mean 4.41
Standard deviation 2.5
Values 3.3 2.2 2.6 6.3 7.7
[23]
HepG2 SMC1A
Mean 41.7
Standard deviation 10
Values 49 35
[24]
HepG2.C3A SMC1A
Mean 33.9
Standard deviation 11
Values 41 26
[25]
HuH.7 SMC1A
Mean 65.2
Standard deviation 32
Values 64 34 98
[26]
SNU475 SMC1A
Mean 65.4
Standard deviation 7.5
Values 71 60
[27]
THLE SMC1A
Mean 132
Standard deviation 23
Values 1.2e+02 1.5e+02
[28]
liver SMC1A
Mean 34.1
Standard deviation 5.1
Values 34 28 40 35
[29]
ref_hepatocyte RAD50
Mean 3.85
Standard deviation 2.1
Values 2.3 2.8 2.9 3.9 7.4
[30]
HepG2 RAD50
Mean 9.45
Standard deviation 2.3
Values 11 7.9
[31]
HepG2.C3A RAD50
Mean 36.9
Standard deviation 0.99
Values 36 38
[32]
HuH.7 RAD50
Mean 19.7
Standard deviation 4.1
Values 15 22 22
[33]
SNU475 RAD50
Mean 17
Standard deviation 2.2
Values 19 15
[34]
THLE RAD50
Mean 26.8
Standard deviation 8.4
Values 33 21
[35]
liver RAD50
Mean 25.2
Standard deviation 5.7
Values 18 26 32 25
[36]
ref_hepatocyte PAXIP1
Mean 2.13
Standard deviation 1.1
Values 3.8 1.3 1.7 2.5 1.3
[37]
HepG2 PAXIP1
Mean 9.07
Standard deviation 1.8
Values 10 7.8
[38]
HepG2.C3A PAXIP1
Mean 8.44
Standard deviation 2
Values 9.9 7
[39]
HuH.7 PAXIP1
Mean 11.3
Standard deviation 1.7
Values 11 9.6 13
[40]
SNU475 PAXIP1
Mean 5.69
Standard deviation 0.49
Values 5.3 6
[41]
THLE PAXIP1
Mean 7.18
Standard deviation 0.93
Values 6.5 7.8
[42]
liver PAXIP1
Mean 3.68
Standard deviation 1.2
Values 4.5 4.8 2.9 2.5
[43]
ref_hepatocyte MDC1
Mean 2.03
Standard deviation 1.1
Values 2.9 1.1 1.1 3.5 1.6
[44]
HepG2 MDC1
Mean 25.1
Standard deviation 0.18
Values 25 25
[45]
HepG2.C3A MDC1
Mean 29.6
Standard deviation 2.6
Values 31 28
[46]
HuH.7 MDC1
Mean 35.9
Standard deviation 14
Values 34 23 51
[47]
SNU475 MDC1
Mean 27.7
Standard deviation 2.6
Values 30 26
[48]
THLE MDC1
Mean 29.5
Standard deviation 7.6
Values 24 35
[49]
liver MDC1
Mean 7.87
Standard deviation 1.2
Values 9.1 6.3 7.8 8.2
[50]
ref_hepatocyte BRCA1
Mean 1.87
Standard deviation 0.88
Values 0.59 2 2.6 2.7 1.4
[51]
HepG2 BRCA1
Mean 13.1
Standard deviation 3
Values 15 11
[52]
HepG2.C3A BRCA1
Mean 27.8
Standard deviation 18
Values 40 15
[53]
HuH.7 BRCA1
Mean 35
Standard deviation 16
Values 39 17 49
[54]
SNU475 BRCA1
Mean 15.2
Standard deviation 6.4
Values 20 11
[55]
THLE BRCA1
Mean 24.5
Standard deviation 0.48
Values 25 24
[56]
liver BRCA1
Mean 8.47
Standard deviation 9.4
Values 4.5 4.3 22 2.5
[57]
ref_hepatocyte ATM
Mean 0.969
Standard deviation 0.7
Values 0.27 1.1 0.7 2.1 0.69
[58]
HepG2 ATM
Mean 17.5
Standard deviation 8.3
Values 23 12
[59]
HepG2.C3A ATM
Mean 47.4
Standard deviation 4.5
Values 51 44
[60]
HuH.7 ATM
Mean 37.5
Standard deviation 9.1
Values 27 44 41
[61]
SNU475 ATM
Mean 31.7
Standard deviation 8.2
Values 26 38
[62]
THLE ATM
Mean 24.9
Standard deviation 4.4
Values 28 22
[63]
liver ATM
Mean 43.7
Standard deviation 31
Values 64 76 17 17
[64]
ref_hepatocyte RAD18
Mean 0.959
Standard deviation 0.59
Values 0.76 0.4 0.63 1.1 1.9
[65]
HepG2 RAD18
Mean 4.69
Standard deviation 2
Values 6.1 3.3
[66]
HepG2.C3A RAD18
Mean 9.56
Standard deviation 5.6
Values 13 5.6
[67]
HuH.7 RAD18
Mean 20.9
Standard deviation 7.1
Values 22 13 28
[68]
SNU475 RAD18
Mean 9.06
Standard deviation 2.7
Values 11 7.2
[69]
THLE RAD18
Mean 15
Standard deviation 0.74
Values 15 16
[70]
liver RAD18
Mean 2.73
Standard deviation 0.4
Values 2.7 3.3 2.4 2.5
[71]
ref_hepatocyte MIR3610
Missing
[72]
HepG2 MIR3610
Missing
[73]
HepG2.C3A MIR3610
Missing
[74]
HuH.7 MIR3610
Missing
[75]
SNU475 MIR3610
Missing
[76]
THLE MIR3610
Missing
[77]
liver MIR3610
Missing
[78]
ref_hepatocyte MRE11
Missing
[79]
HepG2 MRE11
Missing
[80]
HepG2.C3A MRE11
Missing
[81]
HuH.7 MRE11
Missing
[82]
SNU475 MRE11
Missing
[83]
THLE MRE11
Missing
[84]
liver MRE11
Missing