WP_SMALL_CELL_LUNG_CANCER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FN1 | Fibronectin | [1] | 2.16[2] | 2.04[3] | 2.00[4] | 1.72[5] | 1.87[6] | 1.84[7] |
2 | ITGB1 | Integrin beta-1 | [8] | -1.10[9] | -0.67[10] | -0.47[11] | 0.27[12] | 0.28[13] | -0.29[14] |
3 | NFKBIA | NF-kappa-B inhibitor alpha | [15] | -2.38[16] | -3.77[17] | -4.08[18] | -4.71[19] | -2.89[20] | -1.59[21] |
4 | SKP1 | S-phase kinase-associated protein 1 | [22] | -2.31[23] | -1.51[24] | -2.31[25] | -1.70[26] | -1.54[27] | -1.15[28] |
5 | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta | [29] | -5.50[30] | -5.85[31] | -4.57[32] | -5.21[33] | -4.29[34] | -2.62[35] |
6 | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha | [36] | -3.80[37] | -4.47[38] | -4.21[39] | -5.18[40] | -3.51[41] | -3.46[42] |
7 | CKS1B | Cyclin-dependent kinases regulatory subunit 1 | [43] | -3.06[44] | -2.06[45] | -1.27[46] | -2.50[47] | -2.70[48] | -3.51[49] |
8 | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma | [50] | -11.25[51] | [52] | -9.24[53] | -9.03[54] | -9.03[55] | -2.17[56] |
9 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [57] | -0.49[58] | -1.47[59] | -4.09[60] | -3.18[61] | -0.69[62] | -2.29[63] |
10 | AKT1 | RAC-alpha serine/threonine-protein kinase | [64] | -1.25[65] | -1.07[66] | -2.09[67] | -1.25[68] | -1.29[69] | -0.70[70] |
11 | MYC | Myc proto-oncogene protein | [71] | -0.90[72] | -0.83[73] | -2.79[74] | -3.98[75] | -1.68[76] | -2.45[77] |
12 | BCL2L1 | Bcl-2-like protein 1 | [78] | 0.81[79] | 0.60[80] | 1.63[81] | -1.81[82] | -1.49[83] | -1.27[84] |
13 | BAX | Apoptosis regulator BAX | [85] | -1.00[86] | -1.39[87] | -1.78[88] | -2.80[89] | -2.48[90] | -4.41[91] |
14 | LAMC2 | Laminin subunit gamma-2 | [92] | -9.65[93] | -10.48[94] | -9.14[95] | -6.16[96] | -5.08[97] | -6.78[98] |
15 | LAMB3 | Laminin subunit beta-3 | [99] | -4.13[100] | -6.59[101] | -5.07[102] | -1.85[103] | -2.88[104] | -2.83[105] |
16 | CCND1 | G1/S-specific cyclin-D1 | [106] | 1.72[107] | -0.38[108] | 0.52[109] | 0.68[110] | -0.85[111] | 0.60[112] |
17 | IKBKG | NF-kappa-B essential modulator | [113] | -2.22[114] | -1.66[115] | -3.84[116] | -2.04[117] | -3.32[118] | -1.06[119] |
18 | CDK4 | Cyclin-dependent kinase 4 | [120] | 0.00[121] | 0.99[122] | 0.69[123] | -1.01[124] | -0.43[125] | -1.29[126] |
19 | RELA | Transcription factor p65 | [127] | -1.19[128] | -1.29[129] | -1.09[130] | -1.25[131] | -1.41[132] | -1.33[133] |
20 | ITGAV | Integrin alpha-V | [134] | 0.21[135] | 0.42[136] | -0.17[137] | 1.09[138] | 0.90[139] | -0.02[140] |
21 | BIRC3 | Baculoviral IAP repeat-containing protein 3 | [141] | -4.44[142] | -3.01[143] | -5.34[144] | -4.32[145] | -0.61[146] | -2.53[147] |
22 | ITGA6 | Integrin alpha-6 | [148] | -0.98[149] | -0.19[150] | -0.03[151] | -2.34[152] | -4.03[153] | -0.98[154] |
23 | RXRA | Retinoic acid receptor RXR-alpha | [155] | -1.38[156] | -1.18[157] | -0.27[158] | -1.18[159] | -1.58[160] | 1.70[161] |
24 | CYCS | Cytochrome c | [162] | 0.01[163] | 0.61[164] | 0.75[165] | 0.14[166] | 0.48[167] | 0.86[168] |
25 | CKS2 | Cyclin-dependent kinases regulatory subunit 2 | [169] | -0.88[170] | 0.41[171] | 0.30[172] | -1.30[173] | 0.21[174] | -3.35[175] |
26 | CDKN1B | Cyclin-dependent kinase inhibitor 1B | [176] | -1.41[177] | -0.57[178] | -0.30[179] | -2.30[180] | -1.90[181] | -1.36[182] |
27 | NFKBIB | NF-kappa-B inhibitor beta | [183] | -2.49[184] | -2.26[185] | -1.86[186] | -3.01[187] | -2.73[188] | -2.18[189] |
28 | TRAF4 | TNF receptor-associated factor 4 | [190] | -0.95[191] | 0.41[192] | -0.10[193] | -1.54[194] | -1.88[195] | -1.20[196] |
29 | CASP3 | Caspase-3 | [197] | -1.19[198] | -0.11[199] | -2.59[200] | -2.09[201] | -1.16[202] | -1.26[203] |
30 | LAMB2 | Laminin subunit beta-2 | [204] | 0.81[205] | 0.89[206] | -0.09[207] | -0.30[208] | 0.54[209] | 1.64[210] |
31 | MAX | Protein max | [211] | -2.26[212] | -1.88[213] | -2.49[214] | -1.96[215] | -1.49[216] | -1.69[217] |
32 | BID | BH3-interacting domain death agonist | [218] | -1.60[219] | -1.09[220] | -1.40[221] | -1.48[222] | -2.08[223] | -0.28[224] |
33 | CDK2 | Cyclin-dependent kinase 2 | [225] | -1.74[226] | -1.17[227] | -0.73[228] | -1.22[229] | -0.69[230] | -2.64[231] |
34 | AKT2 | RAC-beta serine/threonine-protein kinase | [232] | -0.37[233] | 0.31[234] | 0.51[235] | -0.34[236] | -0.61[237] | 0.68[238] |
35 | BIRC2 | Baculoviral IAP repeat-containing protein 2 | [239] | -1.08[240] | 0.28[241] | -0.71[242] | -0.78[243] | -0.05[244] | 0.27[245] |
36 | PTK2 | Focal adhesion kinase 1 | [246] | -0.59[247] | 0.30[248] | 0.75[249] | 0.75[250] | -0.11[251] | 0.31[252] |
37 | CASP8 | Caspase-8 | [253] | -1.31[254] | -0.33[255] | -1.09[256] | -1.28[257] | -2.08[258] | -1.87[259] |
38 | LAMC1 | Laminin subunit gamma-1 | [260] | 2.02[261] | 0.69[262] | 1.49[263] | 2.58[264] | 2.15[265] | 0.78[266] |
39 | TRAF1 | TNF receptor-associated factor 1 | [267] | -5.75[268] | -5.47[269] | -4.56[270] | -4.73[271] | -4.23[272] | -3.35[273] |
40 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [274] | -1.80[275] | -1.28[276] | -0.12[277] | 0.87[278] | 0.31[279] | 2.55[280] |
41 | PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protei | -1.87[281] | -0.07[282] | 0.20[283] | -1.76[284] | -0.57[285] | 2.03[286] | |
42 | DDB2 | DNA damage-binding protein 2 | [287] | -0.25[288] | -0.32[289] | -1.56[290] | -2.80[291] | -2.28[292] | -1.97[293] |
43 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [294] | -0.66[295] | -0.58[296] | -0.72[297] | -1.44[298] | -0.59[299] | 0.00[300] |
44 | BAK1 | Bcl-2 homologous antagonist/killer | [301] | -0.44[302] | -0.49[303] | -0.45[304] | -0.01[305] | -0.59[306] | -2.24[307] |
45 | TP53 | Cellular tumor antigen p53 | [308] | 0.31[309] | 0.28[310] | 1.10[311] | 0.10[312] | -0.30[313] | -0.49[314] |
46 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [315] | 0.55[316] | 1.17[317] | 1.85[318] | -0.49[319] | 0.01[320] | -0.74[321] |
47 | TRAF2 | TNF receptor-associated factor 2 | [322] | -1.10[323] | -0.63[324] | -0.83[325] | -1.07[326] | -1.13[327] | -1.25[328] |
48 | RXRB | Retinoic acid receptor RXR-beta | [329] | -0.31[330] | 0.42[331] | -0.59[332] | 0.38[333] | -0.80[334] | -0.34[335] |
49 | CDK6 | Cyclin-dependent kinase 6 | [336] | 0.72[337] | 1.82[338] | 0.29[339] | -0.28[340] | 0.46[341] | 1.62[342] |
50 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [343] | -0.42[344] | 1.20[345] | 1.23[346] | -0.54[347] | 0.21[348] | 1.06[349] |
51 | LAMB1 | Laminin subunit beta-1 | [350] | 2.59[351] | 2.55[352] | 3.97[353] | 4.19[354] | 3.31[355] | 1.88[356] |
52 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [357] | -0.81[358] | -0.34[359] | -0.17[360] | -0.94[361] | -0.91[362] | 0.73[363] |
53 | CCNE1 | G1/S-specific cyclin-E1 | [364] | -0.09[365] | 0.43[366] | -1.32[367] | -1.60[368] | -1.06[369] | -5.08[370] |
54 | ZBTB17 | Zinc finger and BTB domain-containing protein 17 | [371] | -0.68[372] | 0.35[373] | -0.36[374] | -0.52[375] | -0.76[376] | -0.32[377] |
55 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | -0.12[378] | 0.80[379] | 1.02[380] | -0.14[381] | -0.05[382] | 0.70[383] | |
56 | RB1 | Retinoblastoma-associated protein | [384] | -0.11[385] | 0.80[386] | 1.43[387] | 1.08[388] | 1.34[389] | 1.02[390] |
57 | ITGA3 | Integrin alpha-3 | [391] | 0.63[392] | -3.68[393] | -4.59[394] | 3.19[395] | 2.82[396] | -1.94[397] |
58 | CASP9 | Caspase-9 | [398] | -1.17[399] | 0.19[400] | -0.62[401] | -0.95[402] | -1.70[403] | -0.99[404] |
59 | E2F1 | Transcription factor E2F1 | [405] | 0.62[406] | 0.88[407] | 1.08[408] | 0.67[409] | 1.05[410] | -4.07[411] |
60 | LAMA5 | Laminin subunit alpha-5 | [412] | 3.60[413] | 3.20[414] | 2.90[415] | 4.81[416] | 2.28[417] | 2.30[418] |
61 | CDKN2B | Cyclin-dependent kinase 4 inhibitor B | [419] | -0.96[420] | -5.02[421] | -1.11[422] | -0.04[423] | 0.20[424] | -2.54[425] |
62 | E2F3 | Transcription factor E2F3 | [426] | 0.39[427] | 0.62[428] | -0.05[429] | 1.43[430] | 0.82[431] | -0.62[432] |
63 | POLK | DNA polymerase kappa | [433] | -2.17[434] | -0.29[435] | 0.03[436] | 0.63[437] | 0.31[438] | 1.64[439] |
64 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -1.71[440] | 0.34[441] | 0.59[442] | -0.07[443] | 0.07[444] | 1.46[445] | |
65 | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 0.56[446] | 2.05[447] | -1.69[448] | -0.92[449] | -0.21[450] | -0.15[451] | |
66 | ITGA2 | Integrin alpha-2 | [452] | 2.78[453] | 3.13[454] | 0.23[455] | 0.18[456] | 3.11[457] | -1.43[458] |
67 | FHIT | Bis(5'-adenosyl)-triphosphatase | [459] | -2.43[460] | -1.86[461] | -2.63[462] | -7.76[463] | -3.67[464] | -0.43[465] |
68 | APAF1 | Apoptotic protease-activating factor 1 | [466] | 0.33[467] | 1.16[468] | 1.48[469] | 1.43[470] | 0.47[471] | 1.04[472] |
69 | TRAF3 | TNF receptor-associated factor 3 | [473] | 1.56[474] | 1.38[475] | 1.06[476] | 1.63[477] | 1.98[478] | 1.47[479] |
70 | COL4A5 | Collagen alpha-5(IV) chain | [480] | 1.94[481] | -6.95[482] | -1.09[483] | 1.52[484] | 2.74[485] | -1.12[486] |
71 | LAMA4 | Laminin subunit alpha-4 | [487] | -6.94[488] | -9.46[489] | -1.43[490] | 0.48[491] | 4.08[492] | 0.97[493] |
72 | TRAF6 | TNF receptor-associated factor 6 | [494] | -0.24[495] | 0.06[496] | 0.69[497] | 0.47[498] | -0.14[499] | 2.46[500] |
73 | CCNE2 | G1/S-specific cyclin-E2 | [501] | -0.91[502] | -0.10[503] | -0.50[504] | 1.84[505] | 1.68[506] | -0.81[507] |
74 | NOS2 | Nitric oxide synthase, inducible | [508] | -1.31[509] | [510] | -7.08[511] | -6.05[512] | -7.00[513] | -7.76[514] |
75 | COL4A2 | Collagen alpha-2(IV) chain | [515] | -1.40[516] | -0.67[517] | -3.30[518] | 5.99[519] | 5.83[520] | 4.70[521] |
76 | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma | [522] | 0.39[523] | 0.81[524] | 1.72[525] | 1.97[526] | 0.93[527] | 2.22[528] |
77 | LAMA3 | Laminin subunit alpha-3 | [529] | 2.20[530] | 2.44[531] | -1.53[532] | 3.29[533] | 0.53[534] | 1.07[535] |
78 | AKT3 | RAC-gamma serine/threonine-protein kinase | [536] | -3.17[537] | -5.32[538] | -4.57[539] | 4.65[540] | 3.54[541] | 3.16[542] |
79 | COL4A1 | Collagen alpha-1(IV) chain | [543] | -4.06[544] | -4.64[545] | -3.22[546] | 6.19[547] | 5.91[548] | 5.62[549] |
80 | TRAF5 | TNF receptor-associated factor 5 | [550] | -0.63[551] | -0.02[552] | 0.43[553] | 4.31[554] | 2.01[555] | 1.42[556] |
81 | CDKN1C | Cyclin-dependent kinase inhibitor 1C | [557] | [558] | -6.18[559] | 0.59[560] | -0.03[561] | -0.72[562] | 1.01[563] |
82 | COL4A6 | Collagen alpha-6(IV) chain | [564] | 3.16[565] | -5.73[566] | -5.10[567] | 0.21[568] | 3.93[569] | -2.07[570] |
83 | E2F2 | Transcription factor E2F2 | [571] | 2.92[572] | 4.22[573] | 3.80[574] | 2.86[575] | 3.12[576] | 0.97[577] |
84 | BCL2 | Apoptosis regulator Bcl-2 | [578] | -4.18[579] | 1.63[580] | -5.71[581] | 0.58[582] | 0.23[583] | 2.78[584] |
85 | RARB | Retinoic acid receptor beta | [585] | 0.11[586] | -2.70[587] | 3.20[588] | 4.63[589] | 3.13[590] | 4.32[591] |
86 | COL4A3 | Collagen alpha-3(IV) chain | [592] | -4.62[593] | -3.97[594] | -2.49[595] | 4.95[596] | -2.34[597] | 3.07[598] |
87 | LAMA1 | Laminin subunit alpha-1 | [599] | -0.61[600] | -2.67[601] | -3.24[602] | 5.46[603] | 6.05[604] | 1.80[605] |
88 | COL4A4 | Collagen alpha-4(IV) chain | [606] | -2.72[607] | -5.15[608] | -0.84[609] | 7.15[610] | 2.69[611] | 5.56[612] |
89 | ITGA2B | Integrin alpha-IIb | [613] | 2.28[614] | 2.97[615] | 3.03[616] | 1.82[617] | 0.12[618] | 2.16[619] |
90 | PTGS2 | Prostaglandin G/H synthase 2 | [620] | [621] | -3.54[622] | -3.22[623] | 1.67[624] | 7.43[625] | 2.38[626] |
91 | LAMC3 | Laminin subunit gamma-3 | [627] | 3.61[628] | -2.77[629] | -4.96[630] | 1.93[631] | -0.53[632] | 6.34[633] |
92 | RXRG | Retinoic acid receptor RXR-gamma | [634] | -5.06[635] | [636] | [637] | -3.25[638] | [639] | 2.05[640] |
93 | LAMA2 | Laminin subunit alpha-2 | [641] | 4.21[642] | 4.52[643] | 2.31[644] | 9.24[645] | 8.94[646] | 12.63[647] |
94 | LAMB4 | Laminin subunit beta-4 | [648] | [649] | [650] | [651] | [652] | [653] | [654] |
95 | BIRC7 | Baculoviral IAP repeat-containing protein 7 | [655] | [656] | [657] | [658] | [659] | [660] | [661] |
96 | BIRC8 | Baculoviral IAP repeat-containing protein 8 | [662] | [663] | [664] | [665] | [666] | [667] | [668] |
97 | MIR4260 | [669] | [670] | [671] | [672] | [673] | [674] | [675] | |
98 | MIR4758 | [676] | [677] | [678] | [679] | [680] | [681] | [682] |