WP_SIGNAL_TRANSDUCTION_THROUGH_IL1R | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | NFKBIA | NF-kappa-B inhibitor alpha | [1] | -0.85[2] | -2.48[3] | -2.49[4] | -3.08[5] | -1.58[6] | -1.07[7] |
2 | JUN | Transcription factor AP-1 | [8] | -0.28[9] | -1.67[10] | -1.03[11] | -1.26[12] | -1.08[13] | -1.74[14] |
3 | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 | [15] | -1.01[16] | -0.56[17] | -1.29[18] | -1.39[19] | -1.91[20] | -1.37[21] |
4 | IL1RN | Interleukin-1 receptor antagonist protein | [22] | -3.44[23] | -0.54[24] | -8.36[25] | [26] | -8.67[27] | -0.53[28] |
5 | IRAK1 | Interleukin-1 receptor-associated kinase 1 | [29] | 1.62[30] | 1.17[31] | 0.52[32] | 1.24[33] | 1.22[34] | -0.62[35] |
6 | ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial | -1.31[36] | -0.45[37] | 0.42[38] | -2.49[39] | -2.57[40] | -1.02[41] | |
7 | TOLLIP | Toll-interacting protein | [42] | -0.06[43] | -0.02[44] | 0.35[45] | -0.59[46] | -1.81[47] | 1.21[48] |
8 | IL1R1 | Interleukin-1 receptor type 1 | [49] | -0.36[50] | -0.57[51] | -0.85[52] | -0.38[53] | 1.90[54] | 0.84[55] |
9 | RELA | Transcription factor p65 | [56] | 0.34[57] | -0.01[58] | 0.50[59] | 0.39[60] | -0.09[61] | -0.81[62] |
10 | MYD88 | Myeloid differentiation primary response protein MyD88 | [63] | 0.02[64] | 0.24[65] | 0.04[66] | -0.60[67] | -0.68[68] | 0.86[69] |
11 | IL1RAP | Interleukin-1 receptor accessory protein | [70] | -1.29[71] | 1.09[72] | 1.10[73] | -1.03[74] | -0.32[75] | 2.25[76] |
12 | MAPK14 | Mitogen-activated protein kinase 14 | [77] | 1.68[78] | 1.91[79] | 1.85[80] | 2.12[81] | 1.21[82] | 1.35[83] |
13 | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7 | [84] | 0.11[85] | 1.33[86] | 1.57[87] | 0.93[88] | 0.73[89] | 0.31[90] |
14 | IRAK2 | Interleukin-1 receptor-associated kinase-like 2 | [91] | 0.13[92] | 0.39[93] | 0.54[94] | -1.99[95] | -0.83[96] | -0.96[97] |
15 | MAPK8 | Mitogen-activated protein kinase 8 | [98] | -1.24[99] | 0.33[100] | -0.43[101] | -0.46[102] | -0.99[103] | -0.45[104] |
16 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [105] | 0.88[106] | 0.71[107] | 0.87[108] | 0.19[109] | 0.72[110] | 0.52[111] |
17 | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha | [112] | 1.11[113] | 2.49[114] | 2.82[115] | 1.09[116] | 1.52[117] | 1.58[118] |
18 | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | [119] | 0.85[120] | 1.66[121] | 2.10[122] | 0.45[123] | 0.40[124] | 0.29[125] |
19 | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | [126] | 0.73[127] | 0.94[128] | 1.42[129] | 0.70[130] | 0.41[131] | 1.25[132] |
20 | TGFB2 | Transforming growth factor beta-2 | [133] | -4.08[134] | -6.46[135] | -0.29[136] | 3.90[137] | 2.11[138] | -2.70[139] |
21 | IL1B | Interleukin-1 beta | [140] | -8.49[141] | -8.20[142] | -3.51[143] | -3.15[144] | 2.05[145] | -5.13[146] |
22 | TGFB1 | Transforming growth factor beta-1 | [147] | 3.68[148] | 2.80[149] | 0.42[150] | 4.28[151] | 3.12[152] | -1.16[153] |
23 | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14 | [154] | -0.19[155] | 0.42[156] | -0.38[157] | 2.51[158] | 1.11[159] | 0.95[160] |
24 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [161] | 0.50[162] | -2.56[163] | 2.66[164] | 1.45[165] | -2.97[166] | -1.55[167] |
25 | TGFB3 | Transforming growth factor beta-3 | [168] | -1.33[169] | -2.05[170] | -1.92[171] | 0.61[172] | -0.84[173] | 0.52[174] |
26 | IL6 | Interleukin-6 | [175] | -8.23[176] | [177] | -4.10[178] | -0.41[179] | 1.72[180] | [181] |
27 | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 | [182] | 2.86[183] | 2.73[184] | 2.82[185] | 2.77[186] | 1.26[187] | 2.86[188] |
28 | TRAF6 | TNF receptor-associated factor 6 | [189] | 1.30[190] | 1.34[191] | 2.28[192] | 2.10[193] | 1.17[194] | 2.97[195] |
29 | TNF | Tumor necrosis factor | [196] | 1.31[197] | -0.67[198] | -4.90[199] | -1.78[200] | -5.39[201] | -1.83[202] |
30 | IRAK3 | Interleukin-1 receptor-associated kinase 3 | [203] | -1.24[204] | -0.10[205] | 2.14[206] | 6.48[207] | 8.34[208] | 5.95[209] |
31 | IL1A | Interleukin-1 alpha | [210] | -0.22[211] | -0.46[212] | -1.27[213] | -0.20[214] | 6.17[215] | -1.52[216] |
32 | IFNA1 | Interferon alpha-1/13 | [217] | [218] | [219] | [220] | [221] | [222] | [223] |
33 | MIR6502 | [224] | [225] | [226] | [227] | [228] | [229] | [230] | |
34 | MIR718 | [231] | [232] | [233] | [234] | [235] | [236] | [237] | |
35 | IFNB1 | Interferon beta | [238] | [239] | [240] | [241] | [242] | [243] | [244] |