WP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNAS Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas 0.11[1] 0.16[2] -0.18[3] 0.18[4] -0.23[5] -1.08[6]
2 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 [7] -1.25[8] -1.57[9] -0.98[10] -1.21[11] -0.35[12] -0.93[13]
3 MAP2K2 Dual specificity mitogen-activated protein kinase kinase 2 [14] -0.27[15] -0.58[16] 0.30[17] -1.51[18] -0.68[19] -1.44[20]
4 RAP1A Ras-related protein Rap-1A [21] -1.37[22] -1.42[23] -0.57[24] -0.88[25] -0.77[26] -1.03[27]
5 MAPKAPK2 MAP kinase-activated protein kinase 2 [28] 0.14[29] -0.81[30] -0.39[31] 0.73[32] 0.29[33] -0.68[34]
6 EGR1 Early growth response protein 1 [35] -2.13[36] -1.63[37] -3.74[38] -2.99[39] -0.99[40] 1.40[41]
7 MAPK1 Mitogen-activated protein kinase 1 [42] 1.39[43] 1.54[44] 1.38[45] 1.19[46] 1.18[47] 2.03[48]
8 NR3C1 Glucocorticoid receptor [49] -0.28[50] -0.70[51] -0.39[52] 0.81[53] 1.27[54] 2.03[55]
9 ELK1 ETS domain-containing protein Elk-1 [56] -0.64[57] -2.76[58] -0.33[59] -0.39[60] 0.54[61] 0.09[62]
10 SRF Serum response factor [63] 1.14[64] 0.72[65] 0.00[66] 0.88[67] 0.30[68] -0.52[69]
11 ATF1 Cyclic AMP-dependent transcription factor ATF-1 [70] -0.95[71] 0.32[72] 0.05[73] -0.51[74] -0.28[75] -0.22[76]
12 MAPK3 Mitogen-activated protein kinase 3 [77] 1.53[78] 1.59[79] 1.64[80] -0.24[81] 0.13[82] -0.78[83]
13 ELK4 ETS domain-containing protein Elk-4 [84] 0.58[85] 1.62[86] 1.36[87] 0.94[88] 1.66[89] 3.24[90]
14 CREB1 Cyclic AMP-responsive element-binding protein 1 [91] 1.40[92] 2.57[93] 3.07[94] 1.88[95] 2.16[96] 2.60[97]
15 BRAF Serine/threonine-protein kinase B-raf [98] -0.07[99] -0.33[100] 1.71[101] 0.08[102] 0.12[103] 2.11[104]
16 RPS6KA5 Ribosomal protein S6 kinase alpha-5 [105] [106] [107] [108] [109] [110] [111]
17 HTR7 5-hydroxytryptamine receptor 7 [112] -2.02[113] -5.96[114] -5.11[115] -1.70[116] 5.34[117] 0.13[118]
18 HTR4 5-hydroxytryptamine receptor 4 [119] -2.65[120] [121] [122] [123] -0.50[124] 5.14[125]
19 HTR6 5-hydroxytryptamine receptor 6 [126] [127] [128] [129] [130] [131] [132]
[1]
ref_hepatocyte GNAS
Mean 120
Standard deviation 56
Values 61 1.7e+02 1.7e+02 1.4e+02 60
[2]
HepG2 GNAS
Mean 357
Standard deviation 65
Values 3.1e+02 4e+02
[3]
HepG2.C3A GNAS
Mean 326
Standard deviation 53
Values 2.9e+02 3.6e+02
[4]
HuH.7 GNAS
Mean 246
Standard deviation 32
Values 2.7e+02 2.1e+02 2.5e+02
[5]
SNU475 GNAS
Mean 397
Standard deviation 89
Values 3.3e+02 4.6e+02
[6]
THLE GNAS
Mean 262
Standard deviation 20
Values 2.5e+02 2.8e+02
[7]
liver GNAS
Mean 67.5
Standard deviation 15
Values 56 54 84 76
[8]
ref_hepatocyte MAP2K1
Mean 28.1
Standard deviation 8.6
Values 32 27 15 27 39
[9]
HepG2 MAP2K1
Mean 32.6
Standard deviation 3.7
Values 30 35
[10]
HepG2.C3A MAP2K1
Mean 23.1
Standard deviation 0.39
Values 23 23
[11]
HuH.7 MAP2K1
Mean 33.2
Standard deviation 6.4
Values 40 27 33
[12]
SNU475 MAP2K1
Mean 35.5
Standard deviation 5.2
Values 39 32
[13]
THLE MAP2K1
Mean 56.5
Standard deviation 3.6
Values 54 59
[14]
liver MAP2K1
Mean 17.5
Standard deviation 8
Values 12 11 28 18
[15]
ref_hepatocyte MAP2K2
Mean 27.7
Standard deviation 8.5
Values 28 26 42 22 20
[16]
HepG2 MAP2K2
Mean 63.6
Standard deviation 21
Values 48 79
[17]
HepG2.C3A MAP2K2
Mean 45.2
Standard deviation 14
Values 36 55
[18]
HuH.7 MAP2K2
Mean 79.3
Standard deviation 9.5
Values 69 82 87
[19]
SNU475 MAP2K2
Mean 28.4
Standard deviation 0.16
Values 28 28
[20]
THLE MAP2K2
Mean 44.5
Standard deviation 0.75
Values 44 45
[21]
liver MAP2K2
Mean 12.1
Standard deviation 3
Values 11 11 17 9.8
[22]
ref_hepatocyte RAP1A
Mean 17.1
Standard deviation 7.2
Values 8.5 28 13 17 20
[23]
HepG2 RAP1A
Mean 18.3
Standard deviation 5.4
Values 22 14
[24]
HepG2.C3A RAP1A
Mean 15.6
Standard deviation 1.3
Values 17 15
[25]
HuH.7 RAP1A
Mean 26.7
Standard deviation 1.9
Values 26 29 25
[26]
SNU475 RAP1A
Mean 27.1
Standard deviation 7
Values 22 32
[27]
THLE RAP1A
Mean 25.7
Standard deviation 2.2
Values 24 27
[28]
liver RAP1A
Mean 9.95
Standard deviation 5.1
Values 5.3 7.4 17 10
[29]
ref_hepatocyte MAPKAPK2
Mean 13.1
Standard deviation 7.6
Values 24 8.7 17 5.2 10
[30]
HepG2 MAPKAPK2
Mean 39.7
Standard deviation 1.4
Values 39 41
[31]
HepG2.C3A MAPKAPK2
Mean 18.1
Standard deviation 4.5
Values 15 21
[32]
HuH.7 MAPKAPK2
Mean 23.2
Standard deviation 2.9
Values 25 20 25
[33]
SNU475 MAPKAPK2
Mean 63.2
Standard deviation 4
Values 60 66
[34]
THLE MAPKAPK2
Mean 40.9
Standard deviation 0.33
Values 41 41
[35]
liver MAPKAPK2
Mean 9.67
Standard deviation 2.5
Values 11 11 10 6
[36]
ref_hepatocyte EGR1
Mean 12.6
Standard deviation 16
Values 11 4 41 6.3 1.1
[37]
HepG2 EGR1
Mean 7.96
Standard deviation 3.6
Values 5.4 10
[38]
HepG2.C3A EGR1
Mean 9.94
Standard deviation 6.1
Values 5.6 14
[39]
HuH.7 EGR1
Mean 2.2
Standard deviation 0.53
Values 2.5 1.6 2.5
[40]
SNU475 EGR1
Mean 4.61
Standard deviation 3.7
Values 2 7.2
[41]
THLE EGR1
Mean 16.3
Standard deviation 16
Values 4.7 28
[42]
liver EGR1
Mean 39.6
Standard deviation 62
Values 4.1 2 1.3e+02 21
[43]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[44]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[45]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[46]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[47]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[48]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[49]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[50]
ref_hepatocyte NR3C1
Mean 7.64
Standard deviation 5.9
Values 3.7 5.2 3 8.9 17
[51]
HepG2 NR3C1
Mean 17.3
Standard deviation 2.6
Values 19 15
[52]
HepG2.C3A NR3C1
Mean 11.5
Standard deviation 0.35
Values 11 12
[53]
HuH.7 NR3C1
Mean 13.6
Standard deviation 7
Values 8.1 21 11
[54]
SNU475 NR3C1
Mean 38.9
Standard deviation 4
Values 36 42
[55]
THLE NR3C1
Mean 47.3
Standard deviation 0.83
Values 48 47
[56]
liver NR3C1
Mean 37
Standard deviation 5.4
Values 35 44 37 32
[57]
ref_hepatocyte ELK1
Mean 6.81
Standard deviation 3.9
Values 7.5 4.4 8.5 1.7 12
[58]
HepG2 ELK1
Mean 12.1
Standard deviation 1.5
Values 11 13
[59]
HepG2.C3A ELK1
Mean 2.45
Standard deviation 0.82
Values 1.9 3
[60]
HuH.7 ELK1
Mean 12.6
Standard deviation 1.8
Values 13 11 14
[61]
SNU475 ELK1
Mean 15.1
Standard deviation 0.2
Values 15 15
[62]
THLE ELK1
Mean 25.4
Standard deviation 3.5
Values 23 28
[63]
liver ELK1
Mean 8.61
Standard deviation 2.4
Values 7.1 6 10 11
[64]
ref_hepatocyte SRF
Mean 6.43
Standard deviation 4.1
Values 12 1.5 6.2 9.2 3.7
[65]
HepG2 SRF
Mean 39.1
Standard deviation 3.7
Values 36 42
[66]
HepG2.C3A SRF
Mean 25.8
Standard deviation 4.2
Values 23 29
[67]
HuH.7 SRF
Mean 14.9
Standard deviation 1.6
Values 16 13 16
[68]
SNU475 SRF
Mean 34.4
Standard deviation 3.7
Values 32 37
[69]
THLE SRF
Mean 20.4
Standard deviation 3.8
Values 18 23
[70]
liver SRF
Mean 5.31
Standard deviation 3.4
Values 9.8 5.8 3.8 1.8
[71]
ref_hepatocyte ATF1
Mean 4.77
Standard deviation 1.6
Values 3.9 3.9 3.1 6.7 6.4
[72]
HepG2 ATF1
Mean 6.84
Standard deviation 1.3
Values 7.8 5.9
[73]
HepG2.C3A ATF1
Mean 14.5
Standard deviation 3.5
Values 17 12
[74]
HuH.7 ATF1
Mean 11.5
Standard deviation 1.2
Values 10 12 13
[75]
SNU475 ATF1
Mean 9.76
Standard deviation 0.062
Values 9.7 9.8
[76]
THLE ATF1
Mean 10.1
Standard deviation 1.6
Values 8.9 11
[77]
liver ATF1
Mean 4.86
Standard deviation 1.2
Values 3.4 4.8 5.1 6.2
[78]
ref_hepatocyte MAPK3
Mean 4.16
Standard deviation 1.3
Values 3.6 3.3 6 5.1 2.8
[79]
HepG2 MAPK3
Mean 33.1
Standard deviation 5.2
Values 29 37
[80]
HepG2.C3A MAPK3
Mean 30.4
Standard deviation 12
Values 22 39
[81]
HuH.7 MAPK3
Mean 30
Standard deviation 4.8
Values 32 25 34
[82]
SNU475 MAPK3
Mean 10.2
Standard deviation 2.4
Values 8.5 12
[83]
THLE MAPK3
Mean 11.6
Standard deviation 1.1
Values 11 12
[84]
liver MAPK3
Mean 2.87
Standard deviation 2.4
Values 0.82 0.81 5 4.8
[85]
ref_hepatocyte ELK4
Mean 2.56
Standard deviation 1.2
Values 3.5 1.4 1.5 4 2.4
[86]
HepG2 ELK4
Mean 10.6
Standard deviation 2.7
Values 12 8.7
[87]
HepG2.C3A ELK4
Mean 19.2
Standard deviation 4.5
Values 16 22
[88]
HuH.7 ELK4
Mean 15.3
Standard deviation 4.1
Values 11 20 15
[89]
SNU475 ELK4
Mean 14.3
Standard deviation 2.9
Values 12 16
[90]
THLE ELK4
Mean 20.8
Standard deviation 3.7
Values 23 18
[91]
liver ELK4
Mean 28.8
Standard deviation 12
Values 40 37 21 17
[92]
ref_hepatocyte CREB1
Mean 1.8
Standard deviation 1.2
Values 1.5 0.81 0.96 3.7 2.1
[93]
HepG2 CREB1
Mean 13.1
Standard deviation 2.8
Values 15 11
[94]
HepG2.C3A CREB1
Mean 26.1
Standard deviation 3.2
Values 28 24
[95]
HuH.7 CREB1
Mean 35.1
Standard deviation 4
Values 31 36 38
[96]
SNU475 CREB1
Mean 19.3
Standard deviation 0.081
Values 19 19
[97]
THLE CREB1
Mean 20.8
Standard deviation 2.1
Values 22 19
[98]
liver CREB1
Mean 13
Standard deviation 3.1
Values 15 16 12 9.3
[99]
ref_hepatocyte BRAF
Mean 1.07
Standard deviation 0.72
Values 2.3 0.67 0.67 0.56 1.2
[100]
HepG2 BRAF
Mean 2.8
Standard deviation 0.62
Values 3.2 2.4
[101]
HepG2.C3A BRAF
Mean 2.07
Standard deviation 0.66
Values 2.5 1.6
[102]
HuH.7 BRAF
Mean 8.12
Standard deviation 5.8
Values 3.4 15 6.4
[103]
SNU475 BRAF
Mean 3.28
Standard deviation 0.16
Values 3.4 3.2
[104]
THLE BRAF
Mean 2.97
Standard deviation 0.38
Values 2.7 3.2
[105]
liver BRAF
Mean 5.48
Standard deviation 2.9
Values 7.9 8 3.1 2.9
[106]
ref_hepatocyte RPS6KA5
Mean 0.385
Standard deviation 0.19
Values 0.65 0.46 0.18 0.21 0.42
[107]
HepG2 RPS6KA5
Missing
[108]
HepG2.C3A RPS6KA5
Missing
[109]
HuH.7 RPS6KA5
Missing
[110]
SNU475 RPS6KA5
Missing
[111]
THLE RPS6KA5
Missing
[112]
liver RPS6KA5
Missing
[113]
ref_hepatocyte HTR7
Mean 0.125
Standard deviation 0.12
Values 0.21 0.24 0.17 0 0
[114]
HepG2 HTR7
Mean 0.0845
Standard deviation 0.059
Values 0.043 0.13
[115]
HepG2.C3A HTR7
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[116]
HuH.7 HTR7
Mean 0.00839
Standard deviation 0.0095
Values 0.019 0.0064 0
[117]
SNU475 HTR7
Mean 0.112
Standard deviation 0.086
Values 0.17 0.051
[118]
THLE HTR7
Mean 12.9
Standard deviation 1.4
Values 12 14
[119]
liver HTR7
Mean 0.161
Standard deviation 0.17
Values 0.11 0.41 0.024 0.1
[120]
ref_hepatocyte HTR4
Mean 0.00488
Standard deviation 0.011
Values 0 0.024 0 0 0
[121]
HepG2 HTR4
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[122]
HepG2.C3A HTR4
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 HTR4
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 HTR4
Mean 0
Standard deviation 0
Values 0 0
[125]
THLE HTR4
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[126]
liver HTR4
Mean 0.204
Standard deviation 0.24
Values 0.54 0.17 0 0.1
[127]
ref_hepatocyte HTR6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 HTR6
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[129]
HepG2.C3A HTR6
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 HTR6
Mean 0.0468
Standard deviation 0.04
Values 0.037 0.013 0.09
[131]
SNU475 HTR6
Mean 0.0164
Standard deviation 0.016
Values 0.0051 0.028
[132]
THLE HTR6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[133]
liver HTR6
Mean 0.0239
Standard deviation 0.028
Values 0.053 0.043 0 0