WP_SERINE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SHMT1 Serine hydroxymethyltransferase, cytosolic [1] -2.69[2] -3.33[3] -3.06[4] -1.09[5] -2.53[6] 0.93[7]
2 SHMT2 Serine hydroxymethyltransferase, mitochondrial [8] 0.19[9] 0.70[10] 0.01[11] 0.09[12] 0.20[13] -0.38[14]
3 PSAT1 Phosphoserine aminotransferase [15] 0.86[16] 0.33[17] 0.19[18] -0.96[19] 0.40[20] -0.10[21]
4 PHGDH D-3-phosphoglycerate dehydrogenase [22] -0.07[23] -0.28[24] 0.79[25] -0.40[26] 0.20[27] -0.60[28]
5 TYMS Thymidylate synthase [29] -0.96[30] -1.12[31] -1.50[32] 0.45[33] -0.66[34] -6.18[35]
6 PSPH Phosphoserine phosphatase [36] 1.07[37] 1.27[38] 1.45[39] 0.83[40] 0.09[41] -2.24[42]
7 DHFR Dihydrofolate reductase [43] 1.85[44] 1.99[45] 2.12[46] 3.01[47] 2.70[48] -0.12[49]
8 SRR Serine racemase [50] -0.91[51] -0.73[52] -0.38[53] 1.82[54] 0.88[55] -0.72[56]
9 MIR6778 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte SHMT1
Mean 76.7
Standard deviation 82
Values 18 1.6e+02 1.7e+02 15 16
[2]
HepG2 SHMT1
Mean 21.2
Standard deviation 4.7
Values 25 18
[3]
HepG2.C3A SHMT1
Mean 18
Standard deviation 5.4
Values 22 14
[4]
HuH.7 SHMT1
Mean 24
Standard deviation 7.5
Values 31 16 25
[5]
SNU475 SHMT1
Mean 19.7
Standard deviation 0.95
Values 19 20
[6]
THLE SHMT1
Mean 18.2
Standard deviation 3.2
Values 16 21
[7]
liver SHMT1
Mean 246
Standard deviation 1.2e+02
Values 1.3e+02 1.6e+02 3.3e+02 3.7e+02
[8]
ref_hepatocyte SHMT2
Mean 66.5
Standard deviation 44
Values 61 78 1.4e+02 27 32
[9]
HepG2 SHMT2
Mean 135
Standard deviation 40
Values 1.1e+02 1.6e+02
[10]
HepG2.C3A SHMT2
Mean 256
Standard deviation 1e+02
Values 1.8e+02 3.3e+02
[11]
HuH.7 SHMT2
Mean 175
Standard deviation 6.4
Values 1.8e+02 1.8e+02 1.7e+02
[12]
SNU475 SHMT2
Mean 38.7
Standard deviation 3
Values 41 37
[13]
THLE SHMT2
Mean 105
Standard deviation 2.1
Values 1.1e+02 1e+02
[14]
liver SHMT2
Mean 86.4
Standard deviation 29
Values 59 67 1e+02 1.2e+02
[15]
ref_hepatocyte PSAT1
Mean 48.6
Standard deviation 21
Values 30 54 63 72 24
[16]
HepG2 PSAT1
Mean 158
Standard deviation 47
Values 1.2e+02 1.9e+02
[17]
HepG2.C3A PSAT1
Mean 145
Standard deviation 27
Values 1.3e+02 1.6e+02
[18]
HuH.7 PSAT1
Mean 145
Standard deviation 48
Values 1.7e+02 90 1.8e+02
[19]
SNU475 PSAT1
Mean 13.6
Standard deviation 1.7
Values 15 12
[20]
THLE PSAT1
Mean 88.3
Standard deviation 16
Values 1e+02 77
[21]
liver PSAT1
Mean 76.6
Standard deviation 64
Values 21 29 1.6e+02 97
[22]
ref_hepatocyte PHGDH
Mean 45.5
Standard deviation 35
Values 10 62 79 71 5.4
[23]
HepG2 PHGDH
Mean 77.2
Standard deviation 35
Values 52 1e+02
[24]
HepG2.C3A PHGDH
Mean 88.7
Standard deviation 46
Values 56 1.2e+02
[25]
HuH.7 PHGDH
Mean 205
Standard deviation 72
Values 2.5e+02 1.2e+02 2.5e+02
[26]
SNU475 PHGDH
Mean 18.9
Standard deviation 2.5
Values 17 21
[27]
THLE PHGDH
Mean 71.9
Standard deviation 8.2
Values 78 66
[28]
liver PHGDH
Mean 50.7
Standard deviation 47
Values 17 21 1.2e+02 46
[29]
ref_hepatocyte TYMS
Mean 24.8
Standard deviation 32
Values 2.5 0.91 3.3 69 49
[30]
HepG2 TYMS
Mean 22.7
Standard deviation 7.9
Values 28 17
[31]
HepG2.C3A TYMS
Mean 26.9
Standard deviation 18
Values 40 14
[32]
HuH.7 TYMS
Mean 23
Standard deviation 12
Values 32 9.1 28
[33]
SNU475 TYMS
Mean 18.5
Standard deviation 1.2
Values 19 18
[34]
THLE TYMS
Mean 21.5
Standard deviation 4.9
Values 18 25
[35]
liver TYMS
Mean 0.58
Standard deviation 0.68
Values 0 0.4 0.35 1.6
[36]
ref_hepatocyte PSPH
Mean 11.7
Standard deviation 13
Values 4.2 4 7.2 34 9.2
[37]
HepG2 PSPH
Mean 44
Standard deviation 1.8
Values 45 43
[38]
HepG2.C3A PSPH
Mean 67
Standard deviation 1.9
Values 68 66
[39]
HuH.7 PSPH
Mean 83.9
Standard deviation 11
Values 97 78 77
[40]
SNU475 PSPH
Mean 11.4
Standard deviation 1.7
Values 10 13
[41]
THLE PSPH
Mean 17.2
Standard deviation 0.015
Values 17 17
[42]
liver PSPH
Mean 4.2
Standard deviation 1.7
Values 3.3 3.1 6.7 3.8
[43]
ref_hepatocyte DHFR
Mean 6.89
Standard deviation 3.8
Values 0.65 9.3 6.3 10 7.9
[44]
HepG2 DHFR
Mean 44.3
Standard deviation 17
Values 56 32
[45]
HepG2.C3A DHFR
Mean 64.7
Standard deviation 42
Values 95 35
[46]
HuH.7 DHFR
Mean 78.4
Standard deviation 42
Values 96 31 1.1e+02
[47]
SNU475 DHFR
Mean 30.2
Standard deviation 0.92
Values 30 31
[48]
THLE DHFR
Mean 61.5
Standard deviation 17
Values 50 73
[49]
liver DHFR
Mean 10.7
Standard deviation 3.8
Values 12 9.2 15 6.4
[50]
ref_hepatocyte SRR
Mean 1.54
Standard deviation 0.55
Values 1.9 2.3 1.3 0.95 1.3
[51]
HepG2 SRR
Mean 1.46
Standard deviation 0.22
Values 1.3 1.6
[52]
HepG2.C3A SRR
Mean 2.19
Standard deviation 0.14
Values 2.1 2.3
[53]
HuH.7 SRR
Mean 3.1
Standard deviation 0.66
Values 2.7 2.8 3.9
[54]
SNU475 SRR
Mean 2.96
Standard deviation 0.9
Values 2.3 3.6
[55]
THLE SRR
Mean 3.88
Standard deviation 0.3
Values 3.7 4.1
[56]
liver SRR
Mean 1.58
Standard deviation 0.76
Values 0.71 1.2 1.9 2.4
[57]
ref_hepatocyte MIR6778
Missing
[58]
HepG2 MIR6778
Missing
[59]
HepG2.C3A MIR6778
Missing
[60]
HuH.7 MIR6778
Missing
[61]
SNU475 MIR6778
Missing
[62]
THLE MIR6778
Missing
[63]
liver MIR6778
Missing