WP_SELENIUM_MICRONUTRIENT_NETWORK | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SAA1 | Serum amyloid A-1 protein | [1] | -14.90[2] | -16.49[3] | -10.44[4] | -11.43[5] | -3.23[6] | -2.26[7] |
2 | ALB | Serum albumin | [8] | 0.96[9] | 2.03[10] | 1.41[11] | -5.93[12] | -6.38[13] | 0.45[14] |
3 | FGG | Fibrinogen gamma chain | [15] | -2.35[16] | -2.93[17] | -1.36[18] | -7.16[19] | -9.68[20] | 0.02[21] |
4 | FGA | Fibrinogen alpha chain | [22] | -2.02[23] | -3.17[24] | -1.26[25] | -6.37[26] | -9.69[27] | 0.69[28] |
5 | SAA2 | Serum amyloid A-2 protein | [29] | -13.94[30] | -13.27[31] | -8.51[32] | -9.80[33] | -4.33[34] | -1.66[35] |
6 | APOA1 | Apolipoprotein A-I | [36] | 0.00[37] | -0.26[38] | -1.59[39] | -7.93[40] | -8.72[41] | -0.57[42] |
7 | SERPINA3 | Alpha-1-antichymotrypsin | [43] | -1.25[44] | -1.96[45] | -3.93[46] | -9.12[47] | -7.23[48] | 0.22[49] |
8 | FGB | Fibrinogen beta chain | [50] | -3.22[51] | -3.95[52] | -0.27[53] | -4.49[54] | -8.33[55] | 1.47[56] |
9 | CRP | C-reactive protein | [57] | [58] | [59] | -13.04[60] | [61] | -11.44[62] | 0.60[63] |
10 | SOD2 | Superoxide dismutase [Mn], mitochondrial | [64] | -0.69[65] | -1.57[66] | -1.09[67] | 0.13[68] | 1.62[69] | -2.25[70] |
11 | SAA4 | Serum amyloid A-4 protein | [71] | -2.75[72] | -3.63[73] | -8.16[74] | -12.77[75] | -7.72[76] | -3.46[77] |
12 | SOD1 | Superoxide dismutase [Cu-Zn] | [78] | 0.83[79] | -0.71[80] | -0.40[81] | 2.43[82] | 1.65[83] | -0.94[84] |
13 | TXN | Thioredoxin | [85] | 1.32[86] | -0.16[87] | 0.67[88] | 3.66[89] | 2.58[90] | -2.69[91] |
14 | PRDX1 | Peroxiredoxin-1 | [92] | 2.74[93] | 0.53[94] | 2.26[95] | 4.37[96] | 3.19[97] | -1.56[98] |
15 | F2 | Prothrombin | [99] | 1.99[100] | 0.94[101] | 2.62[102] | -4.43[103] | -5.40[104] | 0.90[105] |
16 | PLG | Plasminogen | [106] | -7.52[107] | -6.94[108] | 1.88[109] | -6.06[110] | -5.01[111] | 1.27[112] |
17 | GPX2 | Glutathione peroxidase 2 | [113] | 3.39[114] | 1.17[115] | 0.32[116] | -5.03[117] | -5.84[118] | 0.03[119] |
18 | GPX4 | Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | [120] | 2.43[121] | 1.29[122] | 2.28[123] | 3.47[124] | 2.43[125] | -1.22[126] |
19 | TXNRD1 | Thioredoxin reductase 1, cytoplasmic | [127] | 3.64[128] | 1.29[129] | 2.45[130] | 7.60[131] | 5.67[132] | -1.48[133] |
20 | GPX1 | Glutathione peroxidase 1 | [134] | 2.72[135] | 0.85[136] | 2.52[137] | 3.85[138] | 4.19[139] | -0.96[140] |
21 | APOB | Apolipoprotein B-100 | [141] | 6.18[142] | 5.41[143] | 5.89[144] | -1.32[145] | -1.88[146] | 5.44[147] |
22 | PRDX5 | Peroxiredoxin-5, mitochondrial | [148] | 2.26[149] | 0.84[150] | 2.50[151] | 4.13[152] | 2.51[153] | -1.84[154] |
23 | SEPHS2 | Selenide, water dikinase 2 | [155] | 3.15[156] | 1.93[157] | 3.60[158] | 2.70[159] | 1.72[160] | -0.42[161] |
24 | CAT | Catalase | [162] | 2.18[163] | 0.34[164] | 2.14[165] | 2.88[166] | 1.63[167] | 1.07[168] |
25 | SERPINE1 | Plasminogen activator inhibitor 1 | [169] | 5.37[170] | 4.05[171] | -1.38[172] | 2.32[173] | 8.36[174] | -3.30[175] |
26 | PRDX3 | Thioredoxin-dependent peroxide reductase, mitochondrial | [176] | 3.36[177] | 3.10[178] | 3.87[179] | 4.16[180] | 4.33[181] | 0.43[182] |
27 | PRDX4 | Peroxiredoxin-4 | [183] | 2.74[184] | 1.17[185] | 2.11[186] | 4.19[187] | 2.73[188] | 0.24[189] |
28 | PRDX2 | Peroxiredoxin-2 | [190] | 3.27[191] | 1.83[192] | 3.09[193] | 3.35[194] | 3.87[195] | -0.33[196] |
29 | KYNU | Kynureninase | [197] | 1.38[198] | 0.42[199] | -1.18[200] | 1.79[201] | 0.36[202] | -1.99[203] |
30 | GPX3 | Glutathione peroxidase 3 | [204] | 4.55[205] | 1.58[206] | 2.85[207] | 3.10[208] | -2.22[209] | 1.66[210] |
31 | MSRB1 | Methionine-R-sulfoxide reductase B1 | [211] | 2.20[212] | 1.64[213] | 2.65[214] | 2.48[215] | 1.24[216] | -0.25[217] |
32 | CBS | Cystathionine beta-synthase | [218] | 2.75[219] | 1.43[220] | 4.29[221] | 2.50[222] | 3.39[223] | 1.54[224] |
33 | SCARB1 | Scavenger receptor class B member 1 | [225] | 5.20[226] | 3.28[227] | 4.27[228] | 5.20[229] | 3.40[230] | 1.18[231] |
34 | GSR | Glutathione reductase, mitochondrial | [232] | 4.77[233] | 2.83[234] | 4.60[235] | 6.92[236] | 4.71[237] | -0.28[238] |
35 | DIO1 | Type I iodothyronine deiodinase | [239] | 1.98[240] | 0.85[241] | 1.09[242] | -3.97[243] | -3.92[244] | 0.98[245] |
36 | HBB | Hemoglobin subunit beta | [246] | [247] | [248] | [249] | [250] | [251] | -1.07[252] |
37 | PNPO | Pyridoxine-5'-phosphate oxidase | [253] | 4.43[254] | 2.73[255] | 2.91[256] | 4.04[257] | 4.20[258] | 1.85[259] |
38 | CTH | Cystathionine gamma-lyase | [260] | 1.82[261] | -0.47[262] | 2.72[263] | 1.53[264] | 1.41[265] | 0.52[266] |
39 | F7 | Coagulation factor VII | [267] | 1.46[268] | 2.22[269] | 2.30[270] | -4.89[271] | -5.39[272] | 1.12[273] |
40 | NFKB2 | Nuclear factor NF-kappa-B p100 subunit | [274] | 3.47[275] | 2.23[276] | 3.98[277] | 4.75[278] | 4.97[279] | -2.44[280] |
41 | RELA | Transcription factor p65 | [281] | 4.37[282] | 2.33[283] | 3.77[284] | 6.07[285] | 5.35[286] | -0.30[287] |
42 | GGT1 | Glutathione hydrolase 1 proenzyme | [288] | 3.57[289] | 1.76[290] | 2.83[291] | 3.94[292] | -1.23[293] | 1.29[294] |
43 | TXNRD2 | Thioredoxin reductase 2, mitochondrial | [295] | 2.99[296] | 1.39[297] | 2.24[298] | 4.28[299] | 3.92[300] | 0.28[301] |
44 | LDLR | Low-density lipoprotein receptor | [302] | 4.43[303] | 3.73[304] | 6.03[305] | 5.23[306] | 5.79[307] | 1.81[308] |
45 | ICAM1 | Intercellular adhesion molecule 1 | [309] | 6.14[310] | 3.97[311] | 5.69[312] | 6.32[313] | 7.86[314] | 0.17[315] |
46 | CCL2 | C-C motif chemokine 2 | [316] | -9.16[317] | [318] | -8.82[319] | 2.01[320] | 3.54[321] | -3.11[322] |
47 | HBA1 | Hemoglobin subunit alpha | [323] | -3.70[324] | -7.99[325] | -7.25[326] | [327] | -4.82[328] | -3.02[329] |
48 | RFK | Riboflavin kinase | [330] | 4.48[331] | 3.01[332] | 4.97[333] | 6.32[334] | 5.98[335] | 0.48[336] |
49 | FLAD1 | FAD synthase | [337] | 4.29[338] | 2.40[339] | 4.77[340] | 6.40[341] | 5.23[342] | 0.89[343] |
50 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [344] | 4.91[345] | 3.05[346] | 4.14[347] | 5.88[348] | 6.16[349] | 1.03[350] |
51 | INSR | Insulin receptor | [351] | 4.70[352] | 3.81[353] | 6.54[354] | 3.05[355] | 5.02[356] | 4.58[357] |
52 | XDH | Xanthine dehydrogenase/oxidase | [358] | -5.84[359] | -6.21[360] | 0.58[361] | -1.27[362] | 0.13[363] | 3.35[364] |
53 | ABCA1 | ATP-binding cassette sub-family A member 1 | [365] | 5.90[366] | 5.27[367] | 6.35[368] | 7.34[369] | 7.28[370] | 5.79[371] |
54 | KMO | Kynurenine 3-monooxygenase | [372] | -4.69[373] | -4.60[374] | -1.01[375] | 2.72[376] | -2.88[377] | 2.24[378] |
55 | IL1B | Interleukin-1 beta | [379] | -4.46[380] | -5.86[381] | -0.24[382] | 2.54[383] | 7.50[384] | -4.62[385] |
56 | TXNRD3 | Thioredoxin reductase 3 | [386] | 4.10[387] | 2.40[388] | -1.36[389] | 5.17[390] | 4.26[391] | 1.17[392] |
57 | MTR | Methionine synthase | [393] | 6.51[394] | 5.65[395] | 7.10[396] | 9.28[397] | 7.98[398] | 3.94[399] |
58 | IL6 | Interleukin-6 | [400] | -4.20[401] | [402] | -0.84[403] | 5.27[404] | 7.16[405] | [406] |
59 | GGTLC2 | Glutathione hydrolase light chain 2 | [407] | [408] | [409] | -3.88[410] | -1.38[411] | -3.30[412] | -6.79[413] |
60 | ALOX5AP | Arachidonate 5-lipoxygenase-activating protein | [414] | 2.22[415] | -1.16[416] | 1.54[417] | 5.98[418] | 4.80[419] | 0.25[420] |
61 | MTHFR | Methylenetetrahydrofolate reductase | [421] | 5.57[422] | 5.40[423] | 6.94[424] | 8.83[425] | 6.97[426] | 4.39[427] |
62 | ALOX5 | Arachidonate 5-lipoxygenase | [428] | 3.37[429] | -3.52[430] | -2.14[431] | -1.01[432] | -0.37[433] | 3.39[434] |
63 | DIO3 | Thyroxine 5-deiodinase | [435] | [436] | [437] | 0.35[438] | 0.91[439] | -1.62[440] | -2.12[441] |
64 | IFNG | Interferon gamma | [442] | [443] | [444] | [445] | 5.43[446] | [447] | -1.72[448] |
65 | ALOX15B | Arachidonate 15-lipoxygenase B | [449] | -1.24[450] | [451] | 4.98[452] | -0.98[453] | 6.24[454] | 0.54[455] |
66 | PTGS1 | Prostaglandin G/H synthase 1 | [456] | 5.59[457] | -2.86[458] | 0.18[459] | 8.81[460] | 11.01[461] | 3.56[462] |
67 | TNF | Tumor necrosis factor | [463] | 5.34[464] | 1.67[465] | -1.63[466] | 3.91[467] | 0.05[468] | -1.31[469] |
68 | PLAT | Tissue-type plasminogen activator | [470] | 5.95[471] | 5.01[472] | 3.44[473] | 10.94[474] | 10.54[475] | 4.14[476] |
69 | MPO | Myeloperoxidase | [477] | 1.73[478] | -0.20[479] | [480] | 0.15[481] | [482] | 2.15[483] |
70 | SOD3 | Extracellular superoxide dismutase [Cu-Zn] | [484] | 1.06[485] | 0.40[486] | [487] | 8.42[488] | 4.23[489] | 4.98[490] |
71 | PTGS2 | Prostaglandin G/H synthase 2 | [491] | [492] | 0.08[493] | 1.63[494] | 8.99[495] | 14.18[496] | 3.42[497] |
72 | DIO2 | Type II iodothyronine deiodinase | [498] | 3.16[499] | [500] | 2.67[501] | 11.64[502] | 11.10[503] | 2.74[504] |
73 | GGTLC1 | Glutathione hydrolase light chain 1 | [505] | 0.91[506] | 1.98[507] | 3.19[508] | 4.79[509] | [510] | 1.02[511] |
74 | SELENOS | Selenoprotein S | [512] | [513] | [514] | [515] | [516] | [517] | [518] |
75 | SELENOP | Selenoprotein P | [519] | [520] | [521] | [522] | [523] | [524] | [525] |
76 | INS | Insulin | [526] | [527] | [528] | [529] | [530] | [531] | [532] |
77 | SELENOV | Selenoprotein V | [533] | [534] | [535] | [536] | [537] | [538] | [539] |
78 | GGT2 | Inactive glutathione hydrolase 2 | [540] | [541] | [542] | [543] | [544] | [545] | [546] |
79 | SELENON | Selenoprotein N | [547] | [548] | [549] | [550] | [551] | [552] | [553] |
80 | SELENOM | Selenoprotein M | [554] | [555] | [556] | [557] | [558] | [559] | [560] |
81 | SELENOO | Selenoprotein O | [561] | [562] | [563] | [564] | [565] | [566] | [567] |
82 | SAA3P | [568] | [569] | [570] | [571] | [572] | [573] | [574] | |
83 | SOD2-OT1 | [575] | [576] | [577] | [578] | [579] | [580] | [581] | |
84 | GPX6 | Glutathione peroxidase 6 | [582] | [583] | [584] | [585] | [586] | [587] | [588] |
85 | SELENOW | Selenoprotein W | [589] | [590] | [591] | [592] | [593] | [594] | [595] |
86 | SELENOF | Selenoprotein F | [596] | [597] | [598] | [599] | [600] | [601] | [602] |
87 | SELENOI | Ethanolaminephosphotransferase 1 | [603] | [604] | [605] | [606] | [607] | [608] | [609] |
88 | SELENOT | Thioredoxin reductase-like selenoprotein T | [610] | [611] | [612] | [613] | [614] | [615] | [616] |
89 | MIR6886 | [617] | [618] | [619] | [620] | [621] | [622] | [623] | |
90 | SELENOH | Selenoprotein H | [624] | [625] | [626] | [627] | [628] | [629] | [630] |
91 | SELENOK | Selenoprotein K | [631] | [632] | [633] | [634] | [635] | [636] | [637] |