WP_SARS_CORONAVIRUS_AND_INNATE_IMMUNITY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 STAT1 Signal transducer and activator of transcription 1-alpha/beta [1] -0.54[2] -1.36[3] -0.25[4] 1.30[5] -0.40[6] -0.29[7]
2 JAK1 Tyrosine-protein kinase JAK1 [8] 0.05[9] -0.37[10] -0.18[11] -0.60[12] 0.61[13] 0.29[14]
3 IRF9 Interferon regulatory factor 9 [15] -1.28[16] -3.01[17] -2.73[18] -1.60[19] -2.07[20] -1.34[21]
4 IFNAR2 Interferon alpha/beta receptor 2 [22] -1.67[23] -1.92[24] -1.24[25] -2.62[26] -2.06[27] -2.02[28]
5 IRF3 Interferon regulatory factor 3 [29] -0.16[30] 0.10[31] 0.83[32] -0.88[33] -0.72[34] -2.43[35]
6 IFNAR1 Interferon alpha/beta receptor 1 [36] -0.40[37] 0.17[38] -0.13[39] -0.24[40] 0.31[41] 1.19[42]
7 TBK1 Serine/threonine-protein kinase TBK1 [43] -1.10[44] 0.67[45] -0.18[46] -0.74[47] -0.09[48] -0.77[49]
8 STAT2 Signal transducer and activator of transcription 2 [50] -0.43[51] 1.03[52] 0.18[53] 0.30[54] 0.32[55] 1.78[56]
9 TYK2 Non-receptor tyrosine-protein kinase TYK2 [57] 0.68[58] 1.13[59] 1.26[60] -0.48[61] 1.01[62] 0.74[63]
10 TICAM1 TIR domain-containing adapter molecule 1 [64] -1.17[65] -2.18[66] -1.25[67] -2.45[68] -0.84[69] -1.75[70]
11 IFIH1 Interferon-induced helicase C domain-containing protein 1 [71] -2.43[72] -2.25[73] -6.36[74] -2.46[75] -1.66[76] -0.99[77]
12 DDX58 Probable ATP-dependent RNA helicase DDX58 [78] -1.17[79] -1.08[80] -1.91[81] -2.02[82] -0.89[83] -0.13[84]
13 MAVS Mitochondrial antiviral-signaling protein [85] 3.81[86] 3.52[87] 3.13[88] 2.50[89] 2.66[90] 2.10[91]
14 TRAF3 TNF receptor-associated factor 3 [92] 2.43[93] 1.94[94] 1.55[95] 1.60[96] 2.58[97] 0.68[98]
15 TLR3 Toll-like receptor 3 [99] -4.30[100] -4.67[101] -4.99[102] -1.60[103] 0.05[104] -0.19[105]
16 IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon [106] 1.26[107] 1.22[108] 0.12[109] 1.33[110] 1.45[111] -1.48[112]
17 ACE2 Angiotensin-converting enzyme 2 [113] -0.77[114] 0.66[115] -0.31[116] -8.25[117] -7.09[118] -1.32[119]
18 IFNA8 Interferon alpha-8 [120] [121] [122] [123] [124] [125] [126]
19 IFNA4 Interferon alpha-4 [127] [128] [129] [130] [131] [132] [133]
20 IFNA14 Interferon alpha-14 [134] [135] [136] [137] [138] [139] [140]
21 IFNB1 Interferon beta [141] [142] [143] [144] [145] [146] [147]
22 IFNA21 Interferon alpha-21 [148] [149] [150] [151] [152] [153] [154]
23 IFNA6 Interferon alpha-6 [155] [156] [157] [158] [159] [160] [161]
24 IFNA2 Interferon alpha-2 [162] [163] [164] [165] [166] [167] [168]
25 IFNA13 [169] [170] [171] [172] [173] [174] [175]
26 IFNA17 Interferon alpha-17 [176] [177] [178] [179] [180] [181] [182]
27 IFNA5 Interferon alpha-5 [183] [184] [185] [186] [187] [188] [189]
28 IFNA10 Interferon alpha-10 [190] [191] [192] [193] [194] [195] [196]
29 IFNA16 Interferon alpha-16 [197] [198] [199] [200] [201] [202] [203]
30 IFNA7 Interferon alpha-7 [204] [205] [206] [207] [208] [209] [210]
31 IFNA1 Interferon alpha-1/13 [211] [212] [213] [214] [215] [216] [217]
[1]
ref_hepatocyte STAT1
Mean 20.3
Standard deviation 8.7
Values 19 18 12 17 35
[2]
HepG2 STAT1
Mean 42.7
Standard deviation 9.4
Values 49 36
[3]
HepG2.C3A STAT1
Mean 20.1
Standard deviation 7.2
Values 25 15
[4]
HuH.7 STAT1
Mean 41.6
Standard deviation 4.5
Values 40 38 47
[5]
SNU475 STAT1
Mean 216
Standard deviation 1.4e+02
Values 1.1e+02 3.2e+02
[6]
THLE STAT1
Mean 50.3
Standard deviation 2.1
Values 49 52
[7]
liver STAT1
Mean 55.8
Standard deviation 15
Values 38 69 49 67
[8]
ref_hepatocyte JAK1
Mean 15.2
Standard deviation 7.8
Values 18 10 14 6.8 27
[9]
HepG2 JAK1
Mean 47.8
Standard deviation 11
Values 56 40
[10]
HepG2.C3A JAK1
Mean 29.8
Standard deviation 1.3
Values 29 31
[11]
HuH.7 JAK1
Mean 32.5
Standard deviation 3.3
Values 29 32 36
[12]
SNU475 JAK1
Mean 43.1
Standard deviation 5.5
Values 39 47
[13]
THLE JAK1
Mean 75.4
Standard deviation 6.9
Values 70 80
[14]
liver JAK1
Mean 62.3
Standard deviation 9.1
Values 62 75 54 58
[15]
ref_hepatocyte IRF9
Mean 13
Standard deviation 3.9
Values 14 16 17 7.9 10
[16]
HepG2 IRF9
Mean 16.3
Standard deviation 3.8
Values 14 19
[17]
HepG2.C3A IRF9
Mean 4.11
Standard deviation 0.77
Values 3.6 4.7
[18]
HuH.7 IRF9
Mean 4.77
Standard deviation 2
Values 4.6 6.9 2.8
[19]
SNU475 IRF9
Mean 18.5
Standard deviation 3.8
Values 16 21
[20]
THLE IRF9
Mean 10.1
Standard deviation 0.59
Values 9.7 11
[21]
liver IRF9
Mean 17.3
Standard deviation 10
Values 7.3 9.7 24 28
[22]
ref_hepatocyte IFNAR2
Mean 12.8
Standard deviation 6.4
Values 22 7.5 9.2 8 18
[23]
HepG2 IFNAR2
Mean 12.2
Standard deviation 0.31
Values 12 12
[24]
HepG2.C3A IFNAR2
Mean 8.58
Standard deviation 1.2
Values 7.7 9.4
[25]
HuH.7 IFNAR2
Mean 13.2
Standard deviation 0.52
Values 13 14 13
[26]
SNU475 IFNAR2
Mean 8.96
Standard deviation 1.9
Values 7.6 10
[27]
THLE IFNAR2
Mean 9.98
Standard deviation 0.57
Values 9.6 10
[28]
liver IFNAR2
Mean 10.6
Standard deviation 1.7
Values 9.4 11 9 13
[29]
ref_hepatocyte IRF3
Mean 10
Standard deviation 4.1
Values 13 10 15 7.1 4.7
[30]
HepG2 IRF3
Mean 27.2
Standard deviation 6.6
Values 23 32
[31]
HepG2.C3A IRF3
Mean 27.3
Standard deviation 1.4
Values 26 28
[32]
HuH.7 IRF3
Mean 43.3
Standard deviation 14
Values 54 28 47
[33]
SNU475 IRF3
Mean 23.5
Standard deviation 4.3
Values 27 20
[34]
THLE IRF3
Mean 19.9
Standard deviation 0.46
Values 20 20
[35]
liver IRF3
Mean 6.27
Standard deviation 2.8
Values 4 3.7 8.8 8.7
[36]
ref_hepatocyte IFNAR1
Mean 7.46
Standard deviation 3.8
Values 3.9 12 11 3.7 6.8
[37]
HepG2 IFNAR1
Mean 17.2
Standard deviation 4.5
Values 20 14
[38]
HepG2.C3A IFNAR1
Mean 21.2
Standard deviation 0.44
Values 22 21
[39]
HuH.7 IFNAR1
Mean 16.6
Standard deviation 2.6
Values 14 19 17
[40]
SNU475 IFNAR1
Mean 27.1
Standard deviation 2
Values 26 29
[41]
THLE IFNAR1
Mean 30.2
Standard deviation 1.7
Values 29 31
[42]
liver IFNAR1
Mean 57.2
Standard deviation 9.6
Values 49 70 50 60
[43]
ref_hepatocyte TBK1
Mean 6.94
Standard deviation 1.7
Values 8.4 5.2 5 7.8 8.4
[44]
HepG2 TBK1
Mean 9.87
Standard deviation 3.8
Values 13 7.2
[45]
HepG2.C3A TBK1
Mean 28.1
Standard deviation 7.6
Values 33 23
[46]
HuH.7 TBK1
Mean 14.9
Standard deviation 0.71
Values 15 16 14
[47]
SNU475 TBK1
Mean 17.9
Standard deviation 1.5
Values 17 19
[48]
THLE TBK1
Mean 21.3
Standard deviation 2.3
Values 23 20
[49]
liver TBK1
Mean 13.7
Standard deviation 2.9
Values 10 15 13 17
[50]
ref_hepatocyte STAT2
Mean 5.97
Standard deviation 4.9
Values 2.3 13 9.4 2.5 2.7
[51]
HepG2 STAT2
Mean 13.4
Standard deviation 4
Values 16 11
[52]
HepG2.C3A STAT2
Mean 30.9
Standard deviation 3.5
Values 28 33
[53]
HuH.7 STAT2
Mean 16.5
Standard deviation 0.99
Values 17 16 16
[54]
SNU475 STAT2
Mean 31.7
Standard deviation 16
Values 20 43
[55]
THLE STAT2
Mean 24.3
Standard deviation 2
Values 26 23
[56]
liver STAT2
Mean 69
Standard deviation 4.2
Values 68 74 70 64
[57]
ref_hepatocyte TYK2
Mean 4.82
Standard deviation 1.6
Values 5.2 5.6 6.8 2.6 4
[58]
HepG2 TYK2
Mean 23.5
Standard deviation 0.9
Values 24 23
[59]
HepG2.C3A TYK2
Mean 26.8
Standard deviation 2.6
Values 25 29
[60]
HuH.7 TYK2
Mean 28.1
Standard deviation 8.5
Values 31 19 35
[61]
SNU475 TYK2
Mean 14.9
Standard deviation 0.21
Values 15 15
[62]
THLE TYK2
Mean 31.6
Standard deviation 1.6
Values 33 31
[63]
liver TYK2
Mean 27.2
Standard deviation 3.5
Values 30 24 31 24
[64]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 16 3 3.4 0 1.4
[65]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 4.3 8.5
[66]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 2.2 3.1
[67]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 4.9 4.5 5.2
[68]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.9 3.5
[69]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[70]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 2.3 1.4 7.9 7.4
[71]
ref_hepatocyte IFIH1
Mean 4.45
Standard deviation 2
Values 2.9 4.6 2.5 7.6 4.6
[72]
HepG2 IFIH1
Mean 2.51
Standard deviation 0.64
Values 3 2.1
[73]
HepG2.C3A IFIH1
Mean 2.38
Standard deviation 0.31
Values 2.2 2.6
[74]
HuH.7 IFIH1
Mean 0.132
Standard deviation 0.058
Values 0.066 0.17 0.16
[75]
SNU475 IFIH1
Mean 3.48
Standard deviation 0.87
Values 2.9 4.1
[76]
THLE IFIH1
Mean 4.58
Standard deviation 1.1
Values 5.3 3.8
[77]
liver IFIH1
Mean 7.55
Standard deviation 1.8
Values 6.7 7.5 10 5.9
[78]
ref_hepatocyte DDX58
Mean 3.45
Standard deviation 3
Values 5.8 1.7 1.2 1.2 7.5
[79]
HepG2 DDX58
Mean 4.68
Standard deviation 1.6
Values 5.8 3.5
[80]
HepG2.C3A DDX58
Mean 4.13
Standard deviation 1.1
Values 4.9 3.4
[81]
HuH.7 DDX58
Mean 2.24
Standard deviation 0.73
Values 1.9 3.1 1.8
[82]
SNU475 DDX58
Mean 3.67
Standard deviation 0.0023
Values 3.7 3.7
[83]
THLE DDX58
Mean 6.07
Standard deviation 0.0034
Values 6.1 6.1
[84]
liver DDX58
Mean 10.6
Standard deviation 2.3
Values 7.7 12 13 10
[85]
ref_hepatocyte MAVS
Mean 2.3
Standard deviation 1.1
Values 1.7 1.9 1.8 4.3 1.9
[86]
HepG2 MAVS
Mean 98.5
Standard deviation 2.4
Values 1e+02 97
[87]
HepG2.C3A MAVS
Mean 66.9
Standard deviation 0.12
Values 67 67
[88]
HuH.7 MAVS
Mean 48.8
Standard deviation 7.5
Values 41 50 56
[89]
SNU475 MAVS
Mean 56.1
Standard deviation 14
Values 46 66
[90]
THLE MAVS
Mean 47.4
Standard deviation 9.4
Values 41 54
[91]
liver MAVS
Mean 33.3
Standard deviation 8
Values 44 34 26 29
[92]
ref_hepatocyte TRAF3
Mean 1.27
Standard deviation 0.83
Values 1.7 0.6 0.56 0.98 2.5
[93]
HepG2 TRAF3
Mean 20.8
Standard deviation 3.9
Values 18 24
[94]
HepG2.C3A TRAF3
Mean 12.4
Standard deviation 0.058
Values 12 12
[95]
HuH.7 TRAF3
Mean 9.05
Standard deviation 1.3
Values 7.9 8.7 10
[96]
SNU475 TRAF3
Mean 16.6
Standard deviation 0.54
Values 16 17
[97]
THLE TRAF3
Mean 24.7
Standard deviation 3.8
Values 22 27
[98]
liver TRAF3
Mean 6.87
Standard deviation 4
Values 11 9.3 4.4 2.6
[99]
ref_hepatocyte TLR3
Mean 1.04
Standard deviation 0.74
Values 0.89 1.3 0.97 0 2
[100]
HepG2 TLR3
Mean 0.16
Standard deviation 0.0012
Values 0.16 0.16
[101]
HepG2.C3A TLR3
Mean 0.103
Standard deviation 0.036
Values 0.13 0.078
[102]
HuH.7 TLR3
Mean 0.0792
Standard deviation 0.093
Values 0.019 0.19 0.033
[103]
SNU475 TLR3
Mean 1.48
Standard deviation 0.068
Values 1.4 1.5
[104]
THLE TLR3
Mean 3.51
Standard deviation 0.81
Values 4.1 2.9
[105]
liver TLR3
Mean 3.05
Standard deviation 0.49
Values 3.5 3.4 2.5 2.8
[106]
ref_hepatocyte IKBKE
Mean 0.818
Standard deviation 0.8
Values 0.36 0.39 0.25 0.91 2.2
[107]
HepG2 IKBKE
Mean 5.94
Standard deviation 0.2
Values 6.1 5.8
[108]
HepG2.C3A IKBKE
Mean 4.84
Standard deviation 0.7
Values 5.3 4.3
[109]
HuH.7 IKBKE
Mean 2.16
Standard deviation 0.28
Values 2.3 1.8 2.3
[110]
SNU475 IKBKE
Mean 8.87
Standard deviation 0.19
Values 9 8.7
[111]
THLE IKBKE
Mean 7.27
Standard deviation 2.9
Values 5.2 9.3
[112]
liver IKBKE
Mean 0.988
Standard deviation 0.21
Values 0.69 0.98 1.2 1.1
[113]
ref_hepatocyte ACE2
Mean 0.357
Standard deviation 0.39
Values 0 0.41 0.21 0.17 1
[114]
HepG2 ACE2
Mean 0.635
Standard deviation 0.46
Values 0.96 0.31
[115]
HepG2.C3A ACE2
Mean 1.43
Standard deviation 0.89
Values 2.1 0.81
[116]
HuH.7 ACE2
Mean 0.702
Standard deviation 0.38
Values 0.47 1.1 0.5
[117]
SNU475 ACE2
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[118]
THLE ACE2
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[119]
liver ACE2
Mean 0.481
Standard deviation 0.28
Values 0.34 0.9 0.4 0.28
[120]
ref_hepatocyte IFNA8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[121]
HepG2 IFNA8
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A IFNA8
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 IFNA8
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 IFNA8
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[125]
THLE IFNA8
Mean 0
Standard deviation 0
Values 0 0
[126]
liver IFNA8
Mean 0
Standard deviation 0
Values 0 0 0 0
[127]
ref_hepatocyte IFNA4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[128]
HepG2 IFNA4
Missing
[129]
HepG2.C3A IFNA4
Missing
[130]
HuH.7 IFNA4
Missing
[131]
SNU475 IFNA4
Missing
[132]
THLE IFNA4
Missing
[133]
liver IFNA4
Missing
[134]
ref_hepatocyte IFNA14
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 IFNA14
Missing
[136]
HepG2.C3A IFNA14
Missing
[137]
HuH.7 IFNA14
Missing
[138]
SNU475 IFNA14
Missing
[139]
THLE IFNA14
Missing
[140]
liver IFNA14
Missing
[141]
ref_hepatocyte IFNB1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 IFNB1
Missing
[143]
HepG2.C3A IFNB1
Missing
[144]
HuH.7 IFNB1
Missing
[145]
SNU475 IFNB1
Missing
[146]
THLE IFNB1
Missing
[147]
liver IFNB1
Missing
[148]
ref_hepatocyte IFNA21
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 IFNA21
Missing
[150]
HepG2.C3A IFNA21
Missing
[151]
HuH.7 IFNA21
Missing
[152]
SNU475 IFNA21
Missing
[153]
THLE IFNA21
Missing
[154]
liver IFNA21
Missing
[155]
ref_hepatocyte IFNA6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 IFNA6
Missing
[157]
HepG2.C3A IFNA6
Missing
[158]
HuH.7 IFNA6
Missing
[159]
SNU475 IFNA6
Missing
[160]
THLE IFNA6
Missing
[161]
liver IFNA6
Missing
[162]
ref_hepatocyte IFNA2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 IFNA2
Missing
[164]
HepG2.C3A IFNA2
Missing
[165]
HuH.7 IFNA2
Missing
[166]
SNU475 IFNA2
Missing
[167]
THLE IFNA2
Missing
[168]
liver IFNA2
Missing
[169]
ref_hepatocyte IFNA13
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 IFNA13
Missing
[171]
HepG2.C3A IFNA13
Missing
[172]
HuH.7 IFNA13
Missing
[173]
SNU475 IFNA13
Missing
[174]
THLE IFNA13
Missing
[175]
liver IFNA13
Missing
[176]
ref_hepatocyte IFNA17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 IFNA17
Missing
[178]
HepG2.C3A IFNA17
Missing
[179]
HuH.7 IFNA17
Missing
[180]
SNU475 IFNA17
Missing
[181]
THLE IFNA17
Missing
[182]
liver IFNA17
Missing
[183]
ref_hepatocyte IFNA5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[184]
HepG2 IFNA5
Mean 0
Standard deviation 0
Values 0 0
[185]
HepG2.C3A IFNA5
Mean 0
Standard deviation 0
Values 0 0
[186]
HuH.7 IFNA5
Mean 0
Standard deviation 0
Values 0 0 0
[187]
SNU475 IFNA5
Mean 0.00253
Standard deviation 0.0036
Values 0.0051 0
[188]
THLE IFNA5
Mean 0
Standard deviation 0
Values 0 0
[189]
liver IFNA5
Mean 0.00688
Standard deviation 0.008
Values 0.013 0.014 0 0
[190]
ref_hepatocyte IFNA10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[191]
HepG2 IFNA10
Missing
[192]
HepG2.C3A IFNA10
Missing
[193]
HuH.7 IFNA10
Missing
[194]
SNU475 IFNA10
Missing
[195]
THLE IFNA10
Missing
[196]
liver IFNA10
Missing
[197]
ref_hepatocyte IFNA16
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[198]
HepG2 IFNA16
Missing
[199]
HepG2.C3A IFNA16
Missing
[200]
HuH.7 IFNA16
Missing
[201]
SNU475 IFNA16
Missing
[202]
THLE IFNA16
Missing
[203]
liver IFNA16
Missing
[204]
ref_hepatocyte IFNA7
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[205]
HepG2 IFNA7
Missing
[206]
HepG2.C3A IFNA7
Missing
[207]
HuH.7 IFNA7
Missing
[208]
SNU475 IFNA7
Missing
[209]
THLE IFNA7
Missing
[210]
liver IFNA7
Missing
[211]
ref_hepatocyte IFNA1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[212]
HepG2 IFNA1
Mean 0
Standard deviation 0
Values 0 0
[213]
HepG2.C3A IFNA1
Mean 0
Standard deviation 0
Values 0 0
[214]
HuH.7 IFNA1
Mean 0
Standard deviation 0
Values 0 0 0
[215]
SNU475 IFNA1
Mean 0.00485
Standard deviation 0.0003
Values 0.0051 0.0046
[216]
THLE IFNA1
Mean 0
Standard deviation 0
Values 0 0
[217]
liver IFNA1
Mean 0
Standard deviation 0
Values 0 0 0 0