WP_SARSCOV2_B117_VARIANT_ANTAGONISES_INNATE_IMMUNE_ACTIVATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 IRF3 Interferon regulatory factor 3 [1] -1.29[2] -1.07[3] -0.18[4] -1.13[5] -1.36[6] -2.35[7]
2 TBK1 Serine/threonine-protein kinase TBK1 [8] -2.23[9] -0.50[10] -1.18[11] -0.99[12] -0.73[13] -0.69[14]
3 DDX58 Probable ATP-dependent RNA helicase DDX58 [15] -2.30[16] -2.26[17] -2.91[18] -2.27[19] -1.53[20] -0.05[21]
4 MAVS Mitochondrial antiviral-signaling protein [22] 2.69[23] 2.35[24] 2.12[25] 2.25[26] 2.02[27] 2.18[28]
5 TRAF3 TNF receptor-associated factor 3 [29] 1.30[30] 0.77[31] 0.54[32] 1.35[33] 1.94[34] 0.76[35]
6 TRAF6 TNF receptor-associated factor 6 [36] -0.50[37] -0.56[38] 0.17[39] 0.18[40] -0.19[41] 1.74[42]
7 IKBKE Inhibitor of nuclear factor kappa-B kinase subunit epsilon [43] 0.13[44] 0.05[45] -0.89[46] 1.08[47] 0.81[48] -1.40[49]
8 IFNB1 Interferon beta [50] [51] [52] [53] [54] [55] [56]
9 TOMM70 Mitochondrial import receptor subunit TOM70 [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte IRF3
Mean 10
Standard deviation 4.1
Values 13 10 15 7.1 4.7
[2]
HepG2 IRF3
Mean 27.2
Standard deviation 6.6
Values 23 32
[3]
HepG2.C3A IRF3
Mean 27.3
Standard deviation 1.4
Values 26 28
[4]
HuH.7 IRF3
Mean 43.3
Standard deviation 14
Values 54 28 47
[5]
SNU475 IRF3
Mean 23.5
Standard deviation 4.3
Values 27 20
[6]
THLE IRF3
Mean 19.9
Standard deviation 0.46
Values 20 20
[7]
liver IRF3
Mean 6.27
Standard deviation 2.8
Values 4 3.7 8.8 8.7
[8]
ref_hepatocyte TBK1
Mean 6.94
Standard deviation 1.7
Values 8.4 5.2 5 7.8 8.4
[9]
HepG2 TBK1
Mean 9.87
Standard deviation 3.8
Values 13 7.2
[10]
HepG2.C3A TBK1
Mean 28.1
Standard deviation 7.6
Values 33 23
[11]
HuH.7 TBK1
Mean 14.9
Standard deviation 0.71
Values 15 16 14
[12]
SNU475 TBK1
Mean 17.9
Standard deviation 1.5
Values 17 19
[13]
THLE TBK1
Mean 21.3
Standard deviation 2.3
Values 23 20
[14]
liver TBK1
Mean 13.7
Standard deviation 2.9
Values 10 15 13 17
[15]
ref_hepatocyte DDX58
Mean 3.45
Standard deviation 3
Values 5.8 1.7 1.2 1.2 7.5
[16]
HepG2 DDX58
Mean 4.68
Standard deviation 1.6
Values 5.8 3.5
[17]
HepG2.C3A DDX58
Mean 4.13
Standard deviation 1.1
Values 4.9 3.4
[18]
HuH.7 DDX58
Mean 2.24
Standard deviation 0.73
Values 1.9 3.1 1.8
[19]
SNU475 DDX58
Mean 3.67
Standard deviation 0.0023
Values 3.7 3.7
[20]
THLE DDX58
Mean 6.07
Standard deviation 0.0034
Values 6.1 6.1
[21]
liver DDX58
Mean 10.6
Standard deviation 2.3
Values 7.7 12 13 10
[22]
ref_hepatocyte MAVS
Mean 2.3
Standard deviation 1.1
Values 1.7 1.9 1.8 4.3 1.9
[23]
HepG2 MAVS
Mean 98.5
Standard deviation 2.4
Values 1e+02 97
[24]
HepG2.C3A MAVS
Mean 66.9
Standard deviation 0.12
Values 67 67
[25]
HuH.7 MAVS
Mean 48.8
Standard deviation 7.5
Values 41 50 56
[26]
SNU475 MAVS
Mean 56.1
Standard deviation 14
Values 46 66
[27]
THLE MAVS
Mean 47.4
Standard deviation 9.4
Values 41 54
[28]
liver MAVS
Mean 33.3
Standard deviation 8
Values 44 34 26 29
[29]
ref_hepatocyte TRAF3
Mean 1.27
Standard deviation 0.83
Values 1.7 0.6 0.56 0.98 2.5
[30]
HepG2 TRAF3
Mean 20.8
Standard deviation 3.9
Values 18 24
[31]
HepG2.C3A TRAF3
Mean 12.4
Standard deviation 0.058
Values 12 12
[32]
HuH.7 TRAF3
Mean 9.05
Standard deviation 1.3
Values 7.9 8.7 10
[33]
SNU475 TRAF3
Mean 16.6
Standard deviation 0.54
Values 16 17
[34]
THLE TRAF3
Mean 24.7
Standard deviation 3.8
Values 22 27
[35]
liver TRAF3
Mean 6.87
Standard deviation 4
Values 11 9.3 4.4 2.6
[36]
ref_hepatocyte TRAF6
Mean 0.965
Standard deviation 0.32
Values 1.5 0.8 0.7 0.82 1
[37]
HepG2 TRAF6
Mean 4.54
Standard deviation 0.72
Values 5 4
[38]
HepG2.C3A TRAF6
Mean 3.74
Standard deviation 0.086
Values 3.7 3.8
[39]
HuH.7 TRAF6
Mean 5.32
Standard deviation 1
Values 4.5 6.4 5
[40]
SNU475 TRAF6
Mean 5.61
Standard deviation 0.46
Values 5.3 5.9
[41]
THLE TRAF6
Mean 4.31
Standard deviation 0.54
Values 3.9 4.7
[42]
liver TRAF6
Mean 10.3
Standard deviation 0.99
Values 10 12 9.7 9.8
[43]
ref_hepatocyte IKBKE
Mean 0.818
Standard deviation 0.8
Values 0.36 0.39 0.25 0.91 2.2
[44]
HepG2 IKBKE
Mean 5.94
Standard deviation 0.2
Values 6.1 5.8
[45]
HepG2.C3A IKBKE
Mean 4.84
Standard deviation 0.7
Values 5.3 4.3
[46]
HuH.7 IKBKE
Mean 2.16
Standard deviation 0.28
Values 2.3 1.8 2.3
[47]
SNU475 IKBKE
Mean 8.87
Standard deviation 0.19
Values 9 8.7
[48]
THLE IKBKE
Mean 7.27
Standard deviation 2.9
Values 5.2 9.3
[49]
liver IKBKE
Mean 0.988
Standard deviation 0.21
Values 0.69 0.98 1.2 1.1
[50]
ref_hepatocyte IFNB1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[51]
HepG2 IFNB1
Missing
[52]
HepG2.C3A IFNB1
Missing
[53]
HuH.7 IFNB1
Missing
[54]
SNU475 IFNB1
Missing
[55]
THLE IFNB1
Missing
[56]
liver IFNB1
Missing
[57]
ref_hepatocyte TOMM70
Missing
[58]
HepG2 TOMM70
Missing
[59]
HepG2.C3A TOMM70
Missing
[60]
HuH.7 TOMM70
Missing
[61]
SNU475 TOMM70
Missing
[62]
THLE TOMM70
Missing
[63]
liver TOMM70
Missing