WP_RIBOFLAVIN_AND_COQ_DISORDERS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ETFA Electron transfer flavoprotein subunit alpha, mitochondrial [1] -0.55[2] -0.47[3] -0.47[4] -1.11[5] -1.25[6] -0.64[7]
2 COQ9 Ubiquinone biosynthesis protein COQ9, mitochondrial [8] 0.02[9] -0.23[10] -0.93[11] -0.11[12] 0.14[13] -0.08[14]
3 ETFDH Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial -2.91[15] -1.75[16] -1.75[17] -1.57[18] -0.71[19] 1.66[20]
4 APTX Aprataxin [21] 0.56[22] 0.33[23] 0.16[24] 0.16[25] 1.04[26] -1.05[27]
5 RFK Riboflavin kinase [28] 1.17[29] 0.89[30] 1.97[31] 1.77[32] 1.93[33] -0.04[34]
6 FLAD1 FAD synthase [35] 0.98[36] 0.28[37] 1.78[38] 1.84[39] 1.18[40] 0.36[41]
7 COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial [42] 0.26[43] 0.95[44] -0.62[45] 0.63[46] 0.78[47] 0.42[48]
8 PDSS2 Decaprenyl-diphosphate synthase subunit 2 [49] 0.87[50] 0.75[51] 1.18[52] 0.00[53] 0.97[54] 1.14[55]
9 SLC52A2 Solute carrier family 52, riboflavin transporter, member 2 [56] 2.41[57] 2.59[58] 1.22[59] 2.95[60] 2.06[61] -0.68[62]
10 COQ2 4-hydroxybenzoate polyprenyltransferase, mitochondrial [63] 0.15[64] -0.15[65] -0.14[66] -0.24[67] 1.18[68] -0.23[69]
11 COQ7 5-demethoxyubiquinone hydroxylase, mitochondrial [70] 1.89[71] 1.73[72] 0.91[73] 1.04[74] 1.21[75] -0.08[76]
12 PDSS1 Decaprenyl-diphosphate synthase subunit 1 [77] 0.98[78] 1.49[79] 1.42[80] 1.83[81] 1.33[82] -0.06[83]
13 SLC52A1 Solute carrier family 52, riboflavin transporter, member 1 [84] 2.19[85] -3.27[86] -0.42[87] -1.33[88] 1.13[89] -0.01[90]
14 COQ8A Atypical kinase COQ8A, mitochondrial [91] [92] [93] [94] [95] [96] [97]
[1]
ref_hepatocyte ETFA
Mean 138
Standard deviation 79
Values 24 1.9e+02 2.3e+02 1e+02 1.4e+02
[2]
HepG2 ETFA
Mean 109
Standard deviation 18
Values 1.2e+02 96
[3]
HepG2.C3A ETFA
Mean 131
Standard deviation 26
Values 1.5e+02 1.1e+02
[4]
HuH.7 ETFA
Mean 93.7
Standard deviation 22
Values 1.2e+02 75 89
[5]
SNU475 ETFA
Mean 39.5
Standard deviation 7.4
Values 34 45
[6]
THLE ETFA
Mean 43.8
Standard deviation 4.8
Values 40 47
[7]
liver ETFA
Mean 121
Standard deviation 66
Values 56 75 1.7e+02 1.9e+02
[8]
ref_hepatocyte COQ9
Mean 23.8
Standard deviation 6.2
Values 24 26 33 19 17
[9]
HepG2 COQ9
Mean 28.1
Standard deviation 3.8
Values 31 25
[10]
HepG2.C3A COQ9
Mean 26.6
Standard deviation 4.2
Values 30 24
[11]
HuH.7 COQ9
Mean 11.8
Standard deviation 4.2
Values 16 7.9 11
[12]
SNU475 COQ9
Mean 13.7
Standard deviation 1.5
Values 13 15
[13]
THLE COQ9
Mean 19.9
Standard deviation 1.5
Values 21 19
[14]
liver COQ9
Mean 30.9
Standard deviation 11
Values 19 26 33 46
[15]
ref_hepatocyte ETFDH
Mean 22.6
Standard deviation 19
Values 3.7 35 48 8.4 18
[16]
HepG2 ETFDH
Mean 3.48
Standard deviation 1.2
Values 4.3 2.6
[17]
HepG2.C3A ETFDH
Mean 8.81
Standard deviation 2.6
Values 7 11
[18]
HuH.7 ETFDH
Mean 6.33
Standard deviation 0.22
Values 6.2 6.6 6.2
[19]
SNU475 ETFDH
Mean 4.7
Standard deviation 1.4
Values 3.7 5.7
[20]
THLE ETFDH
Mean 10.4
Standard deviation 0.19
Values 10 11
[21]
liver ETFDH
Mean 97.8
Standard deviation 24
Values 69 96 1e+02 1.3e+02
[22]
ref_hepatocyte APTX
Mean 10.6
Standard deviation 4.1
Values 8.4 7.2 7.8 13 17
[23]
HepG2 APTX
Mean 18.1
Standard deviation 0.22
Values 18 18
[24]
HepG2.C3A APTX
Mean 17.6
Standard deviation 2.6
Values 19 16
[25]
HuH.7 APTX
Mean 11.2
Standard deviation 2.5
Values 14 8.7 11
[26]
SNU475 APTX
Mean 7.37
Standard deviation 0.013
Values 7.4 7.4
[27]
THLE APTX
Mean 16.4
Standard deviation 0.99
Values 16 17
[28]
liver APTX
Mean 7.04
Standard deviation 3
Values 3.8 5.4 8.5 10
[29]
ref_hepatocyte RFK
Mean 8.82
Standard deviation 4.5
Values 3.7 8.3 5.4 12 15
[30]
HepG2 RFK
Mean 23
Standard deviation 0.17
Values 23 23
[31]
HepG2.C3A RFK
Mean 21.5
Standard deviation 4.5
Values 25 18
[32]
HuH.7 RFK
Mean 32.6
Standard deviation 9
Values 30 43 26
[33]
SNU475 RFK
Mean 18.6
Standard deviation 0.72
Values 18 19
[34]
THLE RFK
Mean 25.3
Standard deviation 0.65
Values 25 26
[35]
liver RFK
Mean 11.7
Standard deviation 3.9
Values 8.7 8 16 14
[36]
ref_hepatocyte FLAD1
Mean 8.64
Standard deviation 4.7
Values 10 9.1 15 2.9 5.7
[37]
HepG2 FLAD1
Mean 19.7
Standard deviation 3.4
Values 17 22
[38]
HepG2.C3A FLAD1
Mean 13.8
Standard deviation 2.9
Values 16 12
[39]
HuH.7 FLAD1
Mean 27.9
Standard deviation 14
Values 39 12 32
[40]
SNU475 FLAD1
Mean 19.2
Standard deviation 2.8
Values 21 17
[41]
THLE FLAD1
Mean 14.8
Standard deviation 0.35
Values 15 15
[42]
liver FLAD1
Mean 15.2
Standard deviation 8.9
Values 6.8 8.5 21 25
[43]
ref_hepatocyte COQ6
Mean 5.95
Standard deviation 5.4
Values 1.6 8.5 14 2.2 3.1
[44]
HepG2 COQ6
Mean 8.25
Standard deviation 1.3
Values 9.2 7.3
[45]
HepG2.C3A COQ6
Mean 15.1
Standard deviation 0.61
Values 16 15
[46]
HuH.7 COQ6
Mean 3.63
Standard deviation 0.73
Values 4.4 2.9 3.6
[47]
SNU475 COQ6
Mean 5.7
Standard deviation 0.18
Values 5.6 5.8
[48]
THLE COQ6
Mean 7.71
Standard deviation 0.21
Values 7.6 7.9
[49]
liver COQ6
Mean 10.9
Standard deviation 7
Values 4 7.1 12 20
[50]
ref_hepatocyte PDSS2
Mean 5.1
Standard deviation 2
Values 2.7 7.5 6.8 3.9 4.6
[51]
HepG2 PDSS2
Mean 10.8
Standard deviation 2.8
Values 13 8.8
[52]
HepG2.C3A PDSS2
Mean 11.3
Standard deviation 1.6
Values 12 10
[53]
HuH.7 PDSS2
Mean 10.9
Standard deviation 0.57
Values 11 10 11
[54]
SNU475 PDSS2
Mean 3.17
Standard deviation 0.19
Values 3 3.3
[55]
THLE PDSS2
Mean 7.52
Standard deviation 0.72
Values 7 8
[56]
liver PDSS2
Mean 15.4
Standard deviation 2
Values 13 14 16 18
[57]
ref_hepatocyte SLC52A2
Mean 5.09
Standard deviation 1.7
Values 7.7 4.3 5.4 5 3
[58]
HepG2 SLC52A2
Mean 31.2
Standard deviation 4.9
Values 28 35
[59]
HepG2.C3A SLC52A2
Mean 40.3
Standard deviation 10
Values 33 47
[60]
HuH.7 SLC52A2
Mean 11.2
Standard deviation 3.9
Values 14 6.9 12
[61]
SNU475 SLC52A2
Mean 24.4
Standard deviation 2.3
Values 26 23
[62]
THLE SLC52A2
Mean 16.1
Standard deviation 1.6
Values 15 17
[63]
liver SLC52A2
Mean 4.36
Standard deviation 1.9
Values 3 2.5 5.5 6.5
[64]
ref_hepatocyte COQ2
Mean 5.05
Standard deviation 1.9
Values 1.9 5.9 6.6 6.1 4.7
[65]
HepG2 COQ2
Mean 6.49
Standard deviation 2.5
Values 8.3 4.7
[66]
HepG2.C3A COQ2
Mean 5.97
Standard deviation 2.6
Values 7.8 4.2
[67]
HuH.7 COQ2
Mean 4.32
Standard deviation 1.9
Values 6.2 2.4 4.4
[68]
SNU475 COQ2
Mean 2.65
Standard deviation 0.55
Values 2.3 3
[69]
THLE COQ2
Mean 8.62
Standard deviation 1.3
Values 7.7 9.6
[70]
liver COQ2
Mean 5.88
Standard deviation 3
Values 2.3 4.9 7.1 9.2
[71]
ref_hepatocyte COQ7
Mean 3
Standard deviation 1.6
Values 0.67 3 3 5.2 3.1
[72]
HepG2 COQ7
Mean 12.9
Standard deviation 0.69
Values 13 12
[73]
HepG2.C3A COQ7
Mean 13.1
Standard deviation 2.3
Values 15 11
[74]
HuH.7 COQ7
Mean 5.31
Standard deviation 1.2
Values 6.1 4 5.9
[75]
SNU475 COQ7
Mean 3.81
Standard deviation 0.56
Values 3.4 4.2
[76]
THLE COQ7
Mean 5.23
Standard deviation 2.2
Values 3.7 6.8
[77]
liver COQ7
Mean 3.89
Standard deviation 1.3
Values 3 2.8 4 5.7
[78]
ref_hepatocyte PDSS1
Mean 2.39
Standard deviation 0.94
Values 3.2 1.5 1.9 1.8 3.6
[79]
HepG2 PDSS1
Mean 5.47
Standard deviation 0.88
Values 6.1 4.8
[80]
HepG2.C3A PDSS1
Mean 8.85
Standard deviation 4.4
Values 12 5.8
[81]
HuH.7 PDSS1
Mean 6.03
Standard deviation 3.1
Values 8.9 2.8 6.3
[82]
SNU475 PDSS1
Mean 5.28
Standard deviation 1.6
Values 6.4 4.2
[83]
THLE PDSS1
Mean 4.54
Standard deviation 1.2
Values 3.7 5.4
[84]
liver PDSS1
Mean 3.14
Standard deviation 1
Values 1.9 2.8 3.6 4.2
[85]
ref_hepatocyte SLC52A1
Mean 0.0712
Standard deviation 0.11
Values 0 0.098 0.26 0 0
[86]
HepG2 SLC52A1
Mean 0.376
Standard deviation 0.052
Values 0.34 0.41
[87]
HepG2.C3A SLC52A1
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[88]
HuH.7 SLC52A1
Mean 0.0501
Standard deviation 0.0057
Values 0.056 0.045 0.049
[89]
SNU475 SLC52A1
Mean 0.0175
Standard deviation 0.018
Values 0.03 0.0046
[90]
THLE SLC52A1
Mean 0.118
Standard deviation 0.0089
Values 0.12 0.11
[91]
liver SLC52A1
Mean 0.097
Standard deviation 0.032
Values 0.12 0.1 0.12 0.051
[92]
ref_hepatocyte COQ8A
Missing
[93]
HepG2 COQ8A
Missing
[94]
HepG2.C3A COQ8A
Missing
[95]
HuH.7 COQ8A
Missing
[96]
SNU475 COQ8A
Missing
[97]
THLE COQ8A
Missing
[98]
liver COQ8A
Missing