WP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
AGT |
Angiotensinogen |
[1] |
-0.81[2] |
-0.47[3] |
-1.73[4] |
-5.00[5] |
-10.20[6] |
1.11[7] |
2 |
CALM2 |
Calmodulin-2 |
[8] |
-0.49[9] |
-0.24[10] |
-1.39[11] |
-0.14[12] |
0.02[13] |
-2.46[14] |
3 |
ATF4 |
Cyclic AMP-dependent transcription factor ATF-4 |
[15] |
-0.15[16] |
0.34[17] |
0.56[18] |
-1.41[19] |
-0.11[20] |
-2.95[21] |
4 |
CREB3L3 |
Cyclic AMP-responsive element-binding protein 3-like protein 3 |
[22] |
-4.15[23] |
-2.86[24] |
-1.03[25] |
-8.26[26] |
-7.12[27] |
-0.86[28] |
5 |
CALM3 |
Calmodulin-3 |
[29] |
0.96[30] |
0.08[31] |
1.61[32] |
1.28[33] |
0.98[34] |
-2.86[35] |
6 |
CALM1 |
Calmodulin-1 |
[36] |
1.10[37] |
0.52[38] |
1.30[39] |
3.20[40] |
2.33[41] |
0.88[42] |
7 |
CREB3 |
Cyclic AMP-responsive element-binding protein 3 |
[43] |
0.39[44] |
-0.33[45] |
-0.51[46] |
0.45[47] |
0.79[48] |
-1.85[49] |
8 |
ATF6B |
Cyclic AMP-dependent transcription factor ATF-6 beta |
[50] |
1.16[51] |
0.77[52] |
1.14[53] |
2.85[54] |
1.62[55] |
-1.41[56] |
9 |
CAMK1 |
Calcium/calmodulin-dependent protein kinase type 1 |
[57] |
-0.22[58] |
0.60[59] |
0.85[60] |
0.15[61] |
0.64[62] |
-1.70[63] |
10 |
ATF2 |
Cyclic AMP-dependent transcription factor ATF-2 |
[64] |
1.66[65] |
2.09[66] |
2.64[67] |
2.40[68] |
2.03[69] |
0.28[70] |
11 |
AGTR1 |
Type-1 angiotensin II receptor |
[71] |
-6.33[72] |
-5.11[73] |
0.72[74] |
0.34[75] |
-4.20[76] |
0.69[77] |
12 |
CAMK2D |
Calcium/calmodulin-dependent protein kinase type II subunit delta |
[78] |
1.15[79] |
0.84[80] |
2.69[81] |
2.29[82] |
1.34[83] |
0.67[84] |
13 |
ITPR2 |
Inositol 1,4,5-trisphosphate receptor type 2 |
[85] |
1.94[86] |
2.77[87] |
1.55[88] |
1.62[89] |
1.61[90] |
3.13[91] |
14 |
CYP21A2 |
Steroid 21-hydroxylase |
[92] |
-4.84[93] |
-3.53[94] |
-7.58[95] |
-2.62[96] |
-8.07[97] |
-1.01[98] |
15 |
ATF1 |
Cyclic AMP-dependent transcription factor ATF-1 |
[99] |
0.40[100] |
1.04[101] |
1.08[102] |
1.77[103] |
1.51[104] |
-1.22[105] |
16 |
CREB3L2 |
Cyclic AMP-responsive element-binding protein 3-like protein 2 |
[106] |
3.42[107] |
3.16[108] |
3.53[109] |
3.52[110] |
3.01[111] |
0.96[112] |
17 |
CAMK2G |
Calcium/calmodulin-dependent protein
kinase type II subunit gamma |
1.80[113] |
2.39[114] |
2.33[115] |
3.30[116] |
2.72[117] |
0.21[118] |
18 |
CREB3L4 |
Cyclic AMP-responsive element-binding protein 3-like protein 4 |
[119] |
0.44[120] |
0.79[121] |
2.32[122] |
1.99[123] |
1.02[124] |
-1.41[125] |
19 |
ITPR3 |
Inositol 1,4,5-trisphosphate receptor type 3 |
[126] |
6.32[127] |
4.55[128] |
3.36[129] |
3.97[130] |
6.00[131] |
-0.51[132] |
20 |
GNAQ |
Guanine nucleotide-binding protein G(q) subunit alpha |
[133] |
1.10[134] |
1.26[135] |
2.09[136] |
3.20[137] |
3.28[138] |
0.70[139] |
21 |
CREB1 |
Cyclic AMP-responsive element-binding protein 1 |
[140] |
2.74[141] |
3.28[142] |
4.10[143] |
4.16[144] |
3.96[145] |
1.60[146] |
22 |
CAMK1D |
Calcium/calmodulin-dependent protein kinase type 1D |
[147] |
-3.53[148] |
-3.32[149] |
-4.29[150] |
0.93[151] |
0.72[152] |
-0.23[153] |
23 |
CALML4 |
Calmodulin-like protein 4 |
[154] |
1.42[155] |
1.81[156] |
3.42[157] |
2.08[158] |
2.19[159] |
0.35[160] |
24 |
STAR |
Steroidogenic acute regulatory protein, mitochondrial |
[161] |
1.79[162] |
0.58[163] |
-2.75[164] |
-1.54[165] |
0.74[166] |
-4.23[167] |
25 |
CTSG |
Cathepsin G |
[168] |
[169] |
[170] |
[171] |
[172] |
[173] |
-2.90[174] |
26 |
CAMK2B |
Calcium/calmodulin-dependent protein kinase type II subunit beta |
[175] |
-1.51[176] |
-3.45[177] |
-6.09[178] |
-1.25[179] |
-0.75[180] |
0.41[181] |
27 |
CYP11A1 |
Cholesterol side-chain cleavage enzyme, mitochondrial |
[182] |
0.36[183] |
-2.77[184] |
[185] |
-1.65[186] |
2.26[187] |
-0.27[188] |
28 |
PLCB2 |
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 |
[189] |
-0.60[190] |
-6.00[191] |
-7.52[192] |
-0.32[193] |
-1.17[194] |
1.49[195] |
29 |
ITPR1 |
Inositol 1,4,5-trisphosphate receptor type 1 |
[196] |
4.16[197] |
3.43[198] |
4.90[199] |
4.47[200] |
5.19[201] |
3.91[202] |
30 |
ACE |
Angiotensin-converting enzyme |
[203] |
-3.74[204] |
-6.85[205] |
-4.01[206] |
-0.39[207] |
-1.38[208] |
1.44[209] |
31 |
CREB5 |
Cyclic AMP-responsive element-binding protein 5 |
[210] |
1.95[211] |
-2.16[212] |
1.84[213] |
3.08[214] |
3.48[215] |
-0.24[216] |
32 |
CAMK1G |
Calcium/calmodulin-dependent protein kinase type 1G |
[217] |
-4.92[218] |
[219] |
[220] |
-0.26[221] |
-3.22[222] |
-3.19[223] |
33 |
CMA1 |
Chymase |
[224] |
-3.82[225] |
-6.22[226] |
[227] |
-6.12[228] |
[229] |
-3.10[230] |
34 |
REN |
Renin |
[231] |
-1.92[232] |
[233] |
[234] |
-0.25[235] |
[236] |
-2.59[237] |
35 |
HSD3B1 |
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 |
[238] |
-4.09[239] |
-5.36[240] |
2.02[241] |
[242] |
-1.55[243] |
-3.67[244] |
36 |
CREB3L1 |
Cyclic AMP-responsive element-binding protein 3-like protein 1 |
[245] |
1.01[246] |
-2.53[247] |
7.47[248] |
6.92[249] |
7.07[250] |
-0.98[251] |
37 |
CALML3 |
Calmodulin-like protein 3 |
[252] |
-1.59[253] |
-2.03[254] |
-4.24[255] |
[256] |
-1.70[257] |
-3.08[258] |
38 |
HSD3B2 |
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 |
[259] |
-2.56[260] |
[261] |
-0.11[262] |
[263] |
-0.76[264] |
0.04[265] |
39 |
CAMK4 |
Calcium/calmodulin-dependent protein kinase type IV |
[266] |
[267] |
-1.36[268] |
-1.70[269] |
3.06[270] |
4.98[271] |
3.51[272] |
40 |
CYP11B2 |
Cytochrome P450 11B2, mitochondrial |
[273] |
[274] |
[275] |
[276] |
[277] |
[278] |
[279] |
41 |
CALML6 |
Calmodulin-like protein 6 |
[280] |
[281] |
[282] |
[283] |
[284] |
[285] |
[286] |
42 |
CALML5 |
Calmodulin-like protein 5 |
[287] |
[288] |
[289] |
[290] |
[291] |
[292] |
[293] |
43 |
CAMK2A |
Calcium/calmodulin-dependent protein kinase type II subunit alpha |
[294] |
[295] |
[296] |
[297] |
[298] |
[299] |
[300] |
44 |
AGTR2 |
Type-2 angiotensin II receptor |
[301] |
[302] |
[303] |
[304] |
[305] |
[306] |
[307] |
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