WP_REGULATION_OF_APOPTOSIS_BY_PARATHYROID_HORMONERELATED_PROTEIN Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MCL1 Induced myeloid leukemia cell differentiation protein Mcl-1 [1] -0.71[2] -0.48[3] -0.46[4] 0.48[5] 0.72[6] 0.47[7]
2 AKT1 RAC-alpha serine/threonine-protein kinase [8] -0.48[9] -0.43[10] -1.68[11] 0.27[12] 0.04[13] 0.14[14]
3 MYC Myc proto-oncogene protein [15] -0.13[16] -0.19[17] -2.38[18] -2.47[19] -0.35[20] -1.61[21]
4 BCL2L1 Bcl-2-like protein 1 [22] 1.58[23] 1.24[24] 2.04[25] -0.29[26] -0.16[27] -0.43[28]
5 BAX Apoptosis regulator BAX [29] -0.23[30] -0.75[31] -1.38[32] -1.28[33] -1.15[34] -3.57[35]
6 BOK Bcl-2-related ovarian killer protein [36] -0.69[37] 0.02[38] -3.66[39] -1.58[40] -2.20[41] 0.70[42]
7 ITGA6 Integrin alpha-6 [43] -0.22[44] 0.45[45] 0.37[46] -0.83[47] -2.70[48] -0.14[49]
8 BID BH3-interacting domain death agonist [50] -0.83[51] -0.45[52] -0.99[53] 0.03[54] -0.75[55] 0.56[56]
9 BCL2L13 Bcl-2-like protein 13 [57] -1.30[58] -1.11[59] 1.10[60] 0.59[61] 0.30[62] 0.94[63]
10 GSK3A Glycogen synthase kinase-3 alpha [64] 0.06[65] 0.08[66] 0.01[67] 0.40[68] 0.91[69] -1.45[70]
11 BAK1 Bcl-2 homologous antagonist/killer [71] 0.33[72] 0.15[73] -0.05[74] 1.51[75] 0.74[76] -1.40[77]
12 BCL2A1 Bcl-2-related protein A1 [78] -5.33[79] -6.88[80] -11.45[81] -8.94[82] -5.65[83] -4.50[84]
13 BCL2L2 Bcl-2-like protein 2 [85] 1.25[86] 0.22[87] -0.17[88] 0.64[89] 0.89[90] 0.77[91]
14 GSK3B Glycogen synthase kinase-3 beta [92] 0.70[93] 0.62[94] 1.03[95] 2.14[96] 1.71[97] 1.55[98]
15 BCL2L12 Bcl-2-like protein 12 [99] 0.45[100] 1.31[101] 1.71[102] 1.27[103] 1.04[104] -0.76[105]
16 BCL2L10 Bcl-2-like protein 10 [106] -11.73[107] -10.10[108] -7.73[109] -7.08[110] -5.58[111] -1.24[112]
17 BCL2L14 Apoptosis facilitator Bcl-2-like protein 14 [113] -3.68[114] -2.43[115] 3.56[116] -3.85[117] -4.84[118] 0.32[119]
18 BCL2L15 Bcl-2-like protein 15 [120] -1.34[121] -0.32[122] -0.71[123] 0.69[124] -0.36[125] 0.73[126]
19 ITGB4 Integrin beta-4 [127] 5.15[128] 5.50[129] 1.79[130] 4.49[131] 2.09[132] 3.20[133]
20 BCL2 Apoptosis regulator Bcl-2 [134] -3.42[135] 2.27[136] -5.30[137] 2.10[138] 1.56[139] 3.62[140]
21 PTHLH Parathyroid hormone-related protein [141] 1.33[142] 1.15[143] -3.59[144] 4.82[145] 1.82[146] [147]
22 PIK3CG Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [148] [149] [150] 1.66[151] -3.47[152] 4.49[153]
[1]
ref_hepatocyte MCL1
Mean 51.6
Standard deviation 21
Values 68 45 71 19 55
[2]
HepG2 MCL1
Mean 103
Standard deviation 11
Values 1.1e+02 95
[3]
HepG2.C3A MCL1
Mean 88.2
Standard deviation 15
Values 78 99
[4]
HuH.7 MCL1
Mean 96.5
Standard deviation 9.6
Values 89 1.1e+02 94
[5]
SNU475 MCL1
Mean 105
Standard deviation 9
Values 99 1.1e+02
[6]
THLE MCL1
Mean 166
Standard deviation 39
Values 1.4e+02 1.9e+02
[7]
liver MCL1
Mean 77.6
Standard deviation 52
Values 1.4e+02 1.1e+02 41 28
[8]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 19 32 31 55 50
[9]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 86 89
[10]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 68 65
[11]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 35 23 33
[12]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 57 76
[13]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[14]
liver AKT1
Mean 45.1
Standard deviation 25
Values 79 48 34 20
[15]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 89 1.4 23 15 20
[16]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 52 1.3e+02
[17]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 52 73
[18]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 14 18 13
[19]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 8.9 6.9
[20]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[21]
liver MYC
Mean 10.6
Standard deviation 6
Values 5.5 5.9 18 13
[22]
ref_hepatocyte BCL2L1
Mean 26.8
Standard deviation 12
Values 34 16 23 16 44
[23]
HepG2 BCL2L1
Mean 260
Standard deviation 56
Values 2.2e+02 3e+02
[24]
HepG2.C3A BCL2L1
Mean 152
Standard deviation 4.3
Values 1.5e+02 1.5e+02
[25]
HuH.7 BCL2L1
Mean 283
Standard deviation 60
Values 3.2e+02 2.1e+02 3.1e+02
[26]
SNU475 BCL2L1
Mean 32.1
Standard deviation 4.1
Values 35 29
[27]
THLE BCL2L1
Mean 47
Standard deviation 4.7
Values 44 50
[28]
liver BCL2L1
Mean 21.6
Standard deviation 11
Values 14 9.8 31 31
[29]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 34 11 27 30 21
[30]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 58 80
[31]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 33 38
[32]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 34 14 26
[33]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 16 14
[34]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[35]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 1.4 2.5 2.3 2.9
[36]
ref_hepatocyte BOK
Mean 22.1
Standard deviation 14
Values 14 41 32 16 7
[37]
HepG2 BOK
Mean 44.8
Standard deviation 8.4
Values 39 51
[38]
HepG2.C3A BOK
Mean 53.5
Standard deviation 23
Values 37 70
[39]
HuH.7 BOK
Mean 4.52
Standard deviation 0.61
Values 4.8 3.8 5
[40]
SNU475 BOK
Mean 10.9
Standard deviation 1.6
Values 9.8 12
[41]
THLE BOK
Mean 9.45
Standard deviation 0.048
Values 9.5 9.4
[42]
liver BOK
Mean 39
Standard deviation 23
Values 18 23 68 47
[43]
ref_hepatocyte ITGA6
Mean 15.5
Standard deviation 18
Values 7.3 2.3 1.6 42 24
[44]
HepG2 ITGA6
Mean 43.6
Standard deviation 3.8
Values 46 41
[45]
HepG2.C3A ITGA6
Mean 51
Standard deviation 3.8
Values 54 48
[46]
HuH.7 ITGA6
Mean 51.9
Standard deviation 8.3
Values 49 46 61
[47]
SNU475 ITGA6
Mean 12.9
Standard deviation 0.61
Values 12 13
[48]
THLE ITGA6
Mean 4.67
Standard deviation 1.5
Values 3.6 5.7
[49]
liver ITGA6
Mean 15.3
Standard deviation 3.9
Values 13 20 16 12
[50]
ref_hepatocyte BID
Mean 12.3
Standard deviation 4.8
Values 17 12 15 4.5 12
[51]
HepG2 BID
Mean 22.5
Standard deviation 0.74
Values 23 22
[52]
HepG2.C3A BID
Mean 21.5
Standard deviation 4.7
Values 25 18
[53]
HuH.7 BID
Mean 15.9
Standard deviation 4.6
Values 21 12 15
[54]
SNU475 BID
Mean 18.5
Standard deviation 1.4
Values 17 19
[55]
THLE BID
Mean 14.3
Standard deviation 1.7
Values 13 15
[56]
liver BID
Mean 19.7
Standard deviation 11
Values 10 9.4 30 29
[57]
ref_hepatocyte BCL2L13
Mean 11.7
Standard deviation 7.9
Values 9.3 9.2 8 6.4 26
[58]
HepG2 BCL2L13
Mean 15.5
Standard deviation 4.3
Values 12 19
[59]
HepG2.C3A BCL2L13
Mean 13
Standard deviation 1.9
Values 12 14
[60]
HuH.7 BCL2L13
Mean 64.9
Standard deviation 8.4
Values 56 72 67
[61]
SNU475 BCL2L13
Mean 25.8
Standard deviation 7
Values 21 31
[62]
THLE BCL2L13
Mean 28.3
Standard deviation 2.8
Values 26 30
[63]
liver BCL2L13
Mean 24.4
Standard deviation 6.3
Values 18 21 28 31
[64]
ref_hepatocyte GSK3A
Mean 9.38
Standard deviation 5.1
Values 17 6.4 12 7.5 3.9
[65]
HepG2 GSK3A
Mean 31.9
Standard deviation 3.3
Values 30 34
[66]
HepG2.C3A GSK3A
Mean 23.7
Standard deviation 0.26
Values 24 24
[67]
HuH.7 GSK3A
Mean 24.3
Standard deviation 3.3
Values 26 21 26
[68]
SNU475 GSK3A
Mean 18.2
Standard deviation 1.9
Values 20 17
[69]
THLE GSK3A
Mean 34.6
Standard deviation 4.3
Values 32 38
[70]
liver GSK3A
Mean 3.74
Standard deviation 0.84
Values 4.2 3.1 4.7 3
[71]
ref_hepatocyte BAK1
Mean 6.08
Standard deviation 5.2
Values 14 2.6 2.7 2.6 8.3
[72]
HepG2 BAK1
Mean 24.9
Standard deviation 3.2
Values 23 27
[73]
HepG2.C3A BAK1
Mean 16.2
Standard deviation 1.2
Values 17 15
[74]
HuH.7 BAK1
Mean 15.2
Standard deviation 1.3
Values 16 14 16
[75]
SNU475 BAK1
Mean 25.4
Standard deviation 4.7
Values 22 29
[76]
THLE BAK1
Mean 19.9
Standard deviation 2.1
Values 18 21
[77]
liver BAK1
Mean 2.5
Standard deviation 0.66
Values 1.7 2.5 2.5 3.3
[78]
ref_hepatocyte BCL2A1
Mean 5.7
Standard deviation 7.9
Values 19 0.74 2.5 0 6.2
[79]
HepG2 BCL2A1
Mean 0.462
Standard deviation 0.014
Values 0.47 0.45
[80]
HepG2.C3A BCL2A1
Mean 0.116
Standard deviation 0.11
Values 0.19 0.039
[81]
HuH.7 BCL2A1
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[82]
SNU475 BCL2A1
Mean 0.0171
Standard deviation 0.0045
Values 0.02 0.014
[83]
THLE BCL2A1
Mean 0.223
Standard deviation 0.044
Values 0.25 0.19
[84]
liver BCL2A1
Mean 0.273
Standard deviation 0.092
Values 0.38 0.17 0.31 0.23
[85]
ref_hepatocyte BCL2L2
Mean 4.43
Standard deviation 2.3
Values 5.3 1.7 4.1 7.8 3.2
[86]
HepG2 BCL2L2
Mean 34.3
Standard deviation 3.7
Values 32 37
[87]
HepG2.C3A BCL2L2
Mean 12.3
Standard deviation 1.9
Values 11 14
[88]
HuH.7 BCL2L2
Mean 10.2
Standard deviation 1.6
Values 11 11 8.3
[89]
SNU475 BCL2L2
Mean 10.1
Standard deviation 1.9
Values 8.8 11
[90]
THLE BCL2L2
Mean 16.1
Standard deviation 0.12
Values 16 16
[91]
liver BCL2L2
Mean 8.22
Standard deviation 4.6
Values 14 9.2 5.8 3.7
[92]
ref_hepatocyte GSK3B
Mean 4.16
Standard deviation 1.7
Values 4.9 2.1 2.7 5.2 5.9
[93]
HepG2 GSK3B
Mean 22.1
Standard deviation 6
Values 26 18
[94]
HepG2.C3A GSK3B
Mean 15.3
Standard deviation 2.3
Values 17 14
[95]
HuH.7 GSK3B
Mean 21.8
Standard deviation 5.6
Values 15 26 24
[96]
SNU475 GSK3B
Mean 26.9
Standard deviation 2.6
Values 25 29
[97]
THLE GSK3B
Mean 26.7
Standard deviation 2.9
Values 25 29
[98]
liver GSK3B
Mean 13.2
Standard deviation 3.2
Values 16 15 14 8.6
[99]
ref_hepatocyte BCL2L12
Mean 2.81
Standard deviation 1.9
Values 3.6 4.6 4.3 0.64 0.89
[100]
HepG2 BCL2L12
Mean 12.5
Standard deviation 0.6
Values 13 12
[101]
HepG2.C3A BCL2L12
Mean 16.7
Standard deviation 4.4
Values 20 14
[102]
HuH.7 BCL2L12
Mean 23.7
Standard deviation 11
Values 34 12 25
[103]
SNU475 BCL2L12
Mean 9.96
Standard deviation 2.2
Values 12 8.4
[104]
THLE BCL2L12
Mean 11.3
Standard deviation 0.78
Values 11 12
[105]
liver BCL2L12
Mean 1.8
Standard deviation 1.5
Values 0.37 0.59 3 3.3
[106]
ref_hepatocyte BCL2L10
Mean 2.23
Standard deviation 2.1
Values 3.1 5 2.9 0 0.13
[107]
HepG2 BCL2L10
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[108]
HepG2.C3A BCL2L10
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[109]
HuH.7 BCL2L10
Mean 0.0271
Standard deviation 0.018
Values 0.028 0.045 0.0082
[110]
SNU475 BCL2L10
Mean 0.0243
Standard deviation 0.0015
Values 0.025 0.023
[111]
THLE BCL2L10
Mean 0.0911
Standard deviation 0.039
Values 0.12 0.064
[112]
liver BCL2L10
Mean 1.02
Standard deviation 0.87
Values 0.41 0.34 2.2 1.1
[113]
ref_hepatocyte BCL2L14
Mean 0.242
Standard deviation 0.43
Values 0 0.21 0 0 1
[114]
HepG2 BCL2L14
Mean 0.0616
Standard deviation 0.051
Values 0.026 0.097
[115]
HepG2.C3A BCL2L14
Mean 0.107
Standard deviation 0.00023
Values 0.11 0.11
[116]
HuH.7 BCL2L14
Mean 7.33
Standard deviation 1.2
Values 6.2 8.6 7.2
[117]
SNU475 BCL2L14
Mean 0.0247
Standard deviation 0.015
Values 0.035 0.014
[118]
THLE BCL2L14
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[119]
liver BCL2L14
Mean 0.328
Standard deviation 0.35
Values 0.79 0.4 0.094 0.026
[120]
ref_hepatocyte BCL2L15
Mean 0.165
Standard deviation 0.12
Values 0.29 0.28 0.06 0.16 0.039
[121]
HepG2 BCL2L15
Mean 0.212
Standard deviation 0.016
Values 0.22 0.2
[122]
HepG2.C3A BCL2L15
Mean 0.315
Standard deviation 0.036
Values 0.29 0.34
[123]
HuH.7 BCL2L15
Mean 0.26
Standard deviation 0.087
Values 0.28 0.33 0.16
[124]
SNU475 BCL2L15
Mean 0.389
Standard deviation 0.02
Values 0.38 0.4
[125]
THLE BCL2L15
Mean 0.251
Standard deviation 0.11
Values 0.33 0.17
[126]
liver BCL2L15
Mean 0.297
Standard deviation 0.15
Values 0.37 0.47 0.14 0.21
[127]
ref_hepatocyte ITGB4
Mean 0.1
Standard deviation 0.079
Values 0 0.11 0.17 0.18 0.039
[128]
HepG2 ITGB4
Mean 11.6
Standard deviation 4.7
Values 8.3 15
[129]
HepG2.C3A ITGB4
Mean 10.9
Standard deviation 2.2
Values 9.3 12
[130]
HuH.7 ITGB4
Mean 0.893
Standard deviation 0.17
Values 0.69 0.98 1
[131]
SNU475 ITGB4
Mean 3.3
Standard deviation 2.3
Values 1.7 4.9
[132]
THLE ITGB4
Mean 0.838
Standard deviation 0.17
Values 0.96 0.72
[133]
liver ITGB4
Mean 0.998
Standard deviation 0.38
Values 1.4 0.96 1.1 0.51
[134]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.15 0.2 0.12 0.019 0
[135]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.026 0.034
[136]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 0.99 1.3
[137]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[138]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.68 0.55
[139]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[140]
liver BCL2
Mean 1.31
Standard deviation 1
Values 2.5 1.8 0.49 0.49
[141]
ref_hepatocyte PTHLH
Mean 0.0712
Standard deviation 0.16
Values 0.36 0 0 0 0
[142]
HepG2 PTHLH
Mean 0.584
Standard deviation 0.53
Values 0.21 0.96
[143]
HepG2.C3A PTHLH
Mean 0.377
Standard deviation 0.13
Values 0.47 0.28
[144]
HuH.7 PTHLH
Mean 0.0152
Standard deviation 0.017
Values 0 0.013 0.033
[145]
SNU475 PTHLH
Mean 2.96
Standard deviation 1.4
Values 4 2
[146]
THLE PTHLH
Mean 0.492
Standard deviation 0.24
Values 0.32 0.66
[147]
liver PTHLH
Mean 0
Standard deviation 0
Values 0 0 0 0
[148]
ref_hepatocyte PIK3CG
Mean 0.0637
Standard deviation 0.13
Values 0 0.29 0.026 0 0
[149]
HepG2 PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A PIK3CG
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 PIK3CG
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 PIK3CG
Mean 0.296
Standard deviation 0.1
Values 0.37 0.22
[153]
THLE PIK3CG
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[154]
liver PIK3CG
Mean 1.55
Standard deviation 0.43
Values 1.6 1.9 0.94 1.7