WP_QUERCETIN_AND_NFKB_AP1_INDUCED_APOPTOSIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2A6 Cytochrome P450 2A6 [1] -16.53[2] [3] -8.24[4] -11.20[5] -14.20[6] -0.77[7]
2 NFKBIA NF-kappa-B inhibitor alpha [8] 0.27[9] -1.74[10] -1.45[11] -1.45[12] -0.13[13] -0.29[14]
3 JUN Transcription factor AP-1 [15] 0.84[16] -0.92[17] 0.01[18] 0.37[19] 0.37[20] -0.96[21]
4 FOS Proto-oncogene c-Fos [22] -4.69[23] -3.64[24] -3.64[25] -4.10[26] -3.59[27] -0.46[28]
5 ACOX2 Peroxisomal acyl-coenzyme A oxidase 2 [29] -1.09[30] 0.02[31] 0.43[32] -5.80[33] -4.04[34] 1.97[35]
6 NFE2L2 Nuclear factor erythroid 2-related factor 2 [36] 2.09[37] 2.81[38] 3.08[39] 2.54[40] 2.21[41] 1.02[42]
7 VEGFA Vascular endothelial growth factor A [43] 2.54[44] 3.67[45] 2.93[46] 2.51[47] 2.66[48] 1.63[49]
8 KEAP1 Kelch-like ECH-associated protein 1 [50] 1.54[51] 1.23[52] 1.62[53] 1.26[54] 1.68[55] 1.40[56]
9 MMP1 Interstitial collagenase [57] -3.84[58] -7.82[59] [60] 0.32[61] -0.70[62] -11.28[63]
10 MAFK Transcription factor MafK [64] 1.69[65] 0.90[66] 1.06[67] 0.49[68] 0.89[69] -1.30[70]
11 NFKB1 Nuclear factor NF-kappa-B p105 subunit [71] 1.99[72] 1.46[73] 1.91[74] 1.82[75] 2.17[76] 1.30[77]
12 MAFG Transcription factor MafG [78] 3.55[79] 3.43[80] 3.29[81] 5.04[82] 3.46[83] 1.51[84]
13 IKBKB Inhibitor of nuclear factor kappa-B kinase subunit beta [85] 1.85[86] 1.69[87] 2.46[88] 2.33[89] 1.86[90] 2.03[91]
14 NOS1 Nitric oxide synthase, brain [92] -0.23[93] 1.53[94] 0.62[95] 1.40[96] 0.73[97] 1.54[98]
15 PTGS2 Prostaglandin G/H synthase 2 [99] [100] -1.51[101] -0.59[102] 4.94[103] 10.19[104] 3.68[105]
16 MT-CO1 Cytochrome c oxidase subunit 1 [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 38 5.5e+02 5.6e+02 0 4.6
[2]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[3]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.12 1 0.11
[5]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.025 0.06
[6]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[7]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 13 1.8e+02 29 2.1e+02
[8]
ref_hepatocyte NFKBIA
Mean 84.3
Standard deviation 48
Values 1.6e+02 40 90 83 48
[9]
HepG2 NFKBIA
Mean 89.6
Standard deviation 1.2
Values 90 89
[10]
HepG2.C3A NFKBIA
Mean 23
Standard deviation 1.2
Values 22 24
[11]
HuH.7 NFKBIA
Mean 17
Standard deviation 7.2
Values 15 25 11
[12]
SNU475 NFKBIA
Mean 13.5
Standard deviation 0.67
Values 14 13
[13]
THLE NFKBIA
Mean 55.8
Standard deviation 6.4
Values 51 60
[14]
liver NFKBIA
Mean 54.5
Standard deviation 46
Values 24 19 1.2e+02 55
[15]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 66 20 73 26 30
[16]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 42 93
[17]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 13 28
[18]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 14 46 11
[19]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 27 21
[20]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[21]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 12 24 25 8.4
[22]
ref_hepatocyte FOS
Mean 40
Standard deviation 67
Values 9 27 1.6e+02 4 0.65
[23]
HepG2 FOS
Mean 1.37
Standard deviation 1
Values 0.66 2.1
[24]
HepG2.C3A FOS
Mean 2.92
Standard deviation 1.9
Values 1.6 4.3
[25]
HuH.7 FOS
Mean 1.77
Standard deviation 0.38
Values 2.2 1.6 1.5
[26]
SNU475 FOS
Mean 1.02
Standard deviation 0.13
Values 1.1 0.93
[27]
THLE FOS
Mean 2.4
Standard deviation 0.3
Values 2.2 2.6
[28]
liver FOS
Mean 23
Standard deviation 32
Values 5.7 4.8 71 10
[29]
ref_hepatocyte ACOX2
Mean 19.6
Standard deviation 24
Values 1.6 52 39 4.4 1.3
[30]
HepG2 ACOX2
Mean 8.11
Standard deviation 2.8
Values 10 6.1
[31]
HepG2.C3A ACOX2
Mean 18
Standard deviation 1.3
Values 19 17
[32]
HuH.7 ACOX2
Mean 14.5
Standard deviation 1.3
Values 15 15 13
[33]
SNU475 ACOX2
Mean 0.154
Standard deviation 0.11
Values 0.23 0.074
[34]
THLE ACOX2
Mean 0.86
Standard deviation 0.15
Values 0.96 0.76
[35]
liver ACOX2
Mean 60.6
Standard deviation 24
Values 45 37 91 69
[36]
ref_hepatocyte NFE2L2
Mean 15.6
Standard deviation 4.9
Values 11 19 21 18 9.4
[37]
HepG2 NFE2L2
Mean 58.6
Standard deviation 25
Values 76 41
[38]
HepG2.C3A NFE2L2
Mean 99.8
Standard deviation 19
Values 1.1e+02 86
[39]
HuH.7 NFE2L2
Mean 72.7
Standard deviation 3
Values 74 75 69
[40]
SNU475 NFE2L2
Mean 39.6
Standard deviation 2.1
Values 41 38
[41]
THLE NFE2L2
Mean 52.3
Standard deviation 3.2
Values 55 50
[42]
liver NFE2L2
Mean 25
Standard deviation 9.2
Values 15 21 28 36
[43]
ref_hepatocyte VEGFA
Mean 15.4
Standard deviation 8.3
Values 12 25 22 12 5.2
[44]
HepG2 VEGFA
Mean 78.9
Standard deviation 39
Values 51 1.1e+02
[45]
HepG2.C3A VEGFA
Mean 178
Standard deviation 91
Values 1.1e+02 2.4e+02
[46]
HuH.7 VEGFA
Mean 64.6
Standard deviation 7.4
Values 73 62 59
[47]
SNU475 VEGFA
Mean 38.2
Standard deviation 17
Values 50 26
[48]
THLE VEGFA
Mean 70.1
Standard deviation 17
Values 82 58
[49]
liver VEGFA
Mean 37.5
Standard deviation 27
Values 48 70 18 14
[50]
ref_hepatocyte KEAP1
Mean 14.9
Standard deviation 4.1
Values 17 15 20 11 11
[51]
HepG2 KEAP1
Mean 38
Standard deviation 2.6
Values 36 40
[52]
HepG2.C3A KEAP1
Mean 31.6
Standard deviation 0.82
Values 32 31
[53]
HuH.7 KEAP1
Mean 25.2
Standard deviation 5.2
Values 30 20 26
[54]
SNU475 KEAP1
Mean 15.5
Standard deviation 1.8
Values 17 14
[55]
THLE KEAP1
Mean 34.5
Standard deviation 4.9
Values 31 38
[56]
liver KEAP1
Mean 30.9
Standard deviation 7.7
Values 29 23 31 41
[57]
ref_hepatocyte MMP1
Mean 10.4
Standard deviation 23
Values 52 0.12 0.078 0 0.4
[58]
HepG2 MMP1
Mean 0.642
Standard deviation 0.089
Values 0.58 0.7
[59]
HepG2.C3A MMP1
Mean 0.0419
Standard deviation 0.032
Values 0.064 0.019
[60]
HuH.7 MMP1
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 MMP1
Mean 5.69
Standard deviation 7.7
Values 11 0.27
[62]
THLE MMP1
Mean 4.66
Standard deviation 3.3
Values 2.4 7
[63]
liver MMP1
Mean 0.00331
Standard deviation 0.0066
Values 0.013 0 0 0
[64]
ref_hepatocyte MAFK
Mean 6.99
Standard deviation 6
Values 17 0.9 3.6 6.1 7.7
[65]
HepG2 MAFK
Mean 19.8
Standard deviation 11
Values 12 28
[66]
HepG2.C3A MAFK
Mean 11.9
Standard deviation 6.7
Values 7.1 17
[67]
HuH.7 MAFK
Mean 8.06
Standard deviation 2.2
Values 6.6 11 7.1
[68]
SNU475 MAFK
Mean 4.3
Standard deviation 0.066
Values 4.3 4.3
[69]
THLE MAFK
Mean 9.37
Standard deviation 1.2
Values 8.5 10
[70]
liver MAFK
Mean 2.24
Standard deviation 2.1
Values 4.3 3.8 0.56 0.28
[71]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 12 4.7 5.3 3 6.7
[72]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 26 18
[73]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 17 15
[74]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 13 12 14
[75]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 10 9.6
[76]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[77]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 17 15 9.7 7.2
[78]
ref_hepatocyte MAFG
Mean 3.89
Standard deviation 2.8
Values 4.9 0.46 1.5 6.4 6.2
[79]
HepG2 MAFG
Mean 40.1
Standard deviation 17
Values 28 52
[80]
HepG2.C3A MAFG
Mean 38.2
Standard deviation 11
Values 30 46
[81]
HuH.7 MAFG
Mean 21
Standard deviation 4.1
Values 20 26 18
[82]
SNU475 MAFG
Mean 55.9
Standard deviation 10
Values 49 63
[83]
THLE MAFG
Mean 31.1
Standard deviation 0.12
Values 31 31
[84]
liver MAFG
Mean 8.79
Standard deviation 2.6
Values 11 11 6.3 6.8
[85]
ref_hepatocyte IKBKB
Mean 3.48
Standard deviation 0.8
Values 4.2 2.5 3.5 2.9 4.3
[86]
HepG2 IKBKB
Mean 11
Standard deviation 0.46
Values 11 11
[87]
HepG2.C3A IKBKB
Mean 10.2
Standard deviation 1
Values 9.5 11
[88]
HuH.7 IKBKB
Mean 10.6
Standard deviation 1.9
Values 12 8.4 11
[89]
SNU475 IKBKB
Mean 7.65
Standard deviation 1.8
Values 6.4 8.9
[90]
THLE IKBKB
Mean 9.14
Standard deviation 0.21
Values 9.3 9
[91]
liver IKBKB
Mean 11.2
Standard deviation 0.34
Values 12 11 11 11
[92]
ref_hepatocyte NOS1
Mean 0.0628
Standard deviation 0.06
Values 0.033 0.024 0.086 0.16 0.013
[93]
HepG2 NOS1
Mean 0.0472
Standard deviation 0.042
Values 0.077 0.017
[94]
HepG2.C3A NOS1
Mean 0.165
Standard deviation 0.04
Values 0.19 0.14
[95]
HuH.7 NOS1
Mean 0.0531
Standard deviation 0.054
Values 0.11 0.039 0.0082
[96]
SNU475 NOS1
Mean 0.0724
Standard deviation 0.07
Values 0.12 0.023
[97]
THLE NOS1
Mean 0.0754
Standard deviation 0.069
Values 0.12 0.027
[98]
liver NOS1
Mean 0.144
Standard deviation 0.1
Values 0.16 0.19 0 0.23
[99]
ref_hepatocyte PTGS2
Mean 0.032
Standard deviation 0.045
Values 0 0.065 0.095 0 0
[100]
HepG2 PTGS2
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A PTGS2
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[102]
HuH.7 PTGS2
Mean 0.0117
Standard deviation 0.013
Values 0.0094 0.026 0
[103]
SNU475 PTGS2
Mean 0.428
Standard deviation 0.51
Values 0.79 0.07
[104]
THLE PTGS2
Mean 27
Standard deviation 7.8
Values 33 22
[105]
liver PTGS2
Mean 0.325
Standard deviation 0.24
Values 0.26 0.67 0.24 0.13
[106]
ref_hepatocyte MT-CO1
Missing
[107]
HepG2 MT-CO1
Missing
[108]
HepG2.C3A MT-CO1
Missing
[109]
HuH.7 MT-CO1
Missing
[110]
SNU475 MT-CO1
Missing
[111]
THLE MT-CO1
Missing
[112]
liver MT-CO1
Missing