WP_PURINE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 APRT Adenine phosphoribosyltransferase [1] -0.82[2] -0.52[3] -0.86[4] -1.51[5] -0.82[6] -0.54[7]
2 PNP Purine nucleoside phosphorylase [8] -0.40[9] -1.07[10] -0.40[11] -0.78[12] 0.48[13] -0.80[14]
3 ADSL Adenylosuccinate lyase [15] 0.41[16] 0.68[17] 1.11[18] 0.08[19] 0.03[20] -0.11[21]
4 ATIC Bifunctional purine biosynthesis protein PURH [22] 1.39[23] 1.31[24] 1.30[25] 0.69[26] 0.90[27] -0.11[28]
5 DGUOK Deoxyguanosine kinase, mitochondrial [29] -0.47[30] -0.38[31] -0.60[32] -0.24[33] -0.44[34] -0.57[35]
6 ITPA Inosine triphosphate pyrophosphatase [36] 0.17[37] 0.34[38] -1.33[39] 0.15[40] -0.84[41] -0.58[42]
7 PRPS1 Ribose-phosphate pyrophosphokinase 1 [43] [44] [45] [46] [47] [48] [49]
8 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase [50] -0.58[51] -0.31[52] 0.71[53] 1.06[54] 0.92[55] -0.68[56]
9 XDH Xanthine dehydrogenase/oxidase [57] -9.83[58] -8.60[59] -3.06[60] -6.33[61] -4.42[62] 3.92[63]
10 IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 [64] 2.16[65] 1.52[66] 1.30[67] 3.12[68] 2.47[69] -0.09[70]
11 ADA Adenosine deaminase [71] 1.41[72] 0.62[73] -1.36[74] 2.98[75] 0.30[76] 0.13[77]
12 AMPD1 AMP deaminase 1 [78] [79] [80] -0.88[81] -0.79[82] -1.97[83] [84]
13 ADSS2 [85] [86] [87] [88] [89] [90] [91]
[1]
ref_hepatocyte APRT
Mean 64.6
Standard deviation 34
Values 82 74 1.1e+02 20 41
[2]
HepG2 APRT
Mean 67.9
Standard deviation 11
Values 60 76
[3]
HepG2.C3A APRT
Mean 71
Standard deviation 2.4
Values 73 69
[4]
HuH.7 APRT
Mean 52.3
Standard deviation 21
Values 66 29 62
[5]
SNU475 APRT
Mean 19.9
Standard deviation 1.6
Values 19 21
[6]
THLE APRT
Mean 39
Standard deviation 2.5
Values 37 41
[7]
liver APRT
Mean 28.4
Standard deviation 29
Values 4 3.4 52 55
[8]
ref_hepatocyte PNP
Mean 30
Standard deviation 33
Values 86 12 26 2.3 23
[9]
HepG2 PNP
Mean 42.3
Standard deviation 2.8
Values 40 44
[10]
HepG2.C3A PNP
Mean 22.5
Standard deviation 12
Values 31 14
[11]
HuH.7 PNP
Mean 33.5
Standard deviation 12
Values 46 23 31
[12]
SNU475 PNP
Mean 15.3
Standard deviation 6.3
Values 20 11
[13]
THLE PNP
Mean 44.5
Standard deviation 6.2
Values 40 49
[14]
liver PNP
Mean 11
Standard deviation 6
Values 9.7 6.1 20 8.7
[15]
ref_hepatocyte ADSL
Mean 25
Standard deviation 12
Values 21 12 17 34 40
[16]
HepG2 ADSL
Mean 61.7
Standard deviation 4
Values 59 65
[17]
HepG2.C3A ADSL
Mean 63.3
Standard deviation 4.7
Values 67 60
[18]
HuH.7 ADSL
Mean 79.7
Standard deviation 15
Values 94 64 81
[19]
SNU475 ADSL
Mean 23.2
Standard deviation 2.7
Values 25 21
[20]
THLE ADSL
Mean 27.3
Standard deviation 7.7
Values 22 33
[21]
liver ADSL
Mean 14.9
Standard deviation 3.2
Values 11 16 14 18
[22]
ref_hepatocyte ATIC
Mean 24.9
Standard deviation 8.1
Values 28 14 19 32 32
[23]
HepG2 ATIC
Mean 121
Standard deviation 12
Values 1.1e+02 1.3e+02
[24]
HepG2.C3A ATIC
Mean 97.3
Standard deviation 10
Values 90 1e+02
[25]
HuH.7 ATIC
Mean 90.3
Standard deviation 22
Values 1.1e+02 65 1e+02
[26]
SNU475 ATIC
Mean 35.2
Standard deviation 3.4
Values 38 33
[27]
THLE ATIC
Mean 49.5
Standard deviation 10
Values 42 57
[28]
liver ATIC
Mean 14.7
Standard deviation 12
Values 4.1 5.3 21 29
[29]
ref_hepatocyte DGUOK
Mean 21.4
Standard deviation 7.8
Values 32 23 23 16 12
[30]
HepG2 DGUOK
Mean 28.6
Standard deviation 0.085
Values 29 29
[31]
HepG2.C3A DGUOK
Mean 26
Standard deviation 0.71
Values 25 26
[32]
HuH.7 DGUOK
Mean 20.7
Standard deviation 8.1
Values 29 13 20
[33]
SNU475 DGUOK
Mean 15.9
Standard deviation 2.3
Values 14 18
[34]
THLE DGUOK
Mean 16.8
Standard deviation 0.74
Values 16 17
[35]
liver DGUOK
Mean 9.23
Standard deviation 8.2
Values 2.2 2.1 17 15
[36]
ref_hepatocyte ITPA
Mean 21
Standard deviation 5.1
Values 28 15 22 17 22
[37]
HepG2 ITPA
Mean 44
Standard deviation 4.2
Values 41 47
[38]
HepG2.C3A ITPA
Mean 42.1
Standard deviation 1.5
Values 41 43
[39]
HuH.7 ITPA
Mean 12.3
Standard deviation 5.6
Values 17 6 14
[40]
SNU475 ITPA
Mean 20.4
Standard deviation 4.7
Values 17 24
[41]
THLE ITPA
Mean 12.5
Standard deviation 2.1
Values 11 14
[42]
liver ITPA
Mean 8.99
Standard deviation 7.5
Values 2.4 2.6 16 15
[43]
ref_hepatocyte PRPS1
Mean 18.8
Standard deviation 5.2
Values 22 17 16 13 26
[44]
HepG2 PRPS1
Missing
[45]
HepG2.C3A PRPS1
Missing
[46]
HuH.7 PRPS1
Missing
[47]
SNU475 PRPS1
Missing
[48]
THLE PRPS1
Missing
[49]
liver PRPS1
Missing
[50]
ref_hepatocyte HPRT1
Mean 13.6
Standard deviation 5.4
Values 8.9 15 7.3 17 20
[51]
HepG2 HPRT1
Mean 16.9
Standard deviation 0.27
Values 17 17
[52]
HepG2.C3A HPRT1
Mean 17.3
Standard deviation 2.3
Values 19 16
[53]
HuH.7 HPRT1
Mean 32.8
Standard deviation 5.1
Values 38 28 32
[54]
SNU475 HPRT1
Mean 24.8
Standard deviation 3.3
Values 22 27
[55]
THLE HPRT1
Mean 27.5
Standard deviation 1.6
Values 26 29
[56]
liver HPRT1
Mean 5.44
Standard deviation 5.1
Values 1.1 1.6 7.1 12
[57]
ref_hepatocyte XDH
Mean 5.26
Standard deviation 5.8
Values 2.8 13 9.2 0 0.81
[58]
HepG2 XDH
Mean 0.0107
Standard deviation 0.0091
Values 0.0043 0.017
[59]
HepG2.C3A XDH
Mean 0.0215
Standard deviation 0.03
Values 0.043 0
[60]
HuH.7 XDH
Mean 0.929
Standard deviation 0.041
Values 0.91 0.98 0.9
[61]
SNU475 XDH
Mean 0.0574
Standard deviation 0.055
Values 0.096 0.019
[62]
THLE XDH
Mean 0.262
Standard deviation 0.11
Values 0.18 0.34
[63]
liver XDH
Mean 51.2
Standard deviation 29
Values 87 61 19 38
[64]
ref_hepatocyte IMPDH1
Mean 4.53
Standard deviation 3.3
Values 5.1 1.2 1.2 8.6 6.6
[65]
HepG2 IMPDH1
Mean 37.5
Standard deviation 10
Values 30 45
[66]
HepG2.C3A IMPDH1
Mean 20.5
Standard deviation 4.3
Values 17 24
[67]
HuH.7 IMPDH1
Mean 16.5
Standard deviation 2.6
Values 17 14 19
[68]
SNU475 IMPDH1
Mean 34.6
Standard deviation 1.1
Values 35 34
[69]
THLE IMPDH1
Mean 26.8
Standard deviation 3.7
Values 24 29
[70]
liver IMPDH1
Mean 2.72
Standard deviation 0.62
Values 3.4 2.2 2.2 3.1
[71]
ref_hepatocyte ADA
Mean 1.88
Standard deviation 0.53
Values 2.6 1.8 1.6 1.2 2.2
[72]
HepG2 ADA
Mean 9.29
Standard deviation 5.2
Values 5.6 13
[73]
HepG2.C3A ADA
Mean 4.58
Standard deviation 0.33
Values 4.8 4.3
[74]
HuH.7 ADA
Mean 1.08
Standard deviation 0.11
Values 0.96 1.1 1.1
[75]
SNU475 ADA
Mean 13
Standard deviation 2
Values 12 14
[76]
THLE ADA
Mean 2.48
Standard deviation 0.3
Values 2.7 2.3
[77]
liver ADA
Mean 1.32
Standard deviation 0.66
Values 0.69 0.81 1.9 1.9
[78]
ref_hepatocyte AMPD1
Mean 0.0195
Standard deviation 0.044
Values 0 0.098 0 0 0
[79]
HepG2 AMPD1
Mean 0
Standard deviation 0
Values 0 0
[80]
HepG2.C3A AMPD1
Mean 0
Standard deviation 0
Values 0 0
[81]
HuH.7 AMPD1
Mean 0.0156
Standard deviation 0.027
Values 0.047 0 0
[82]
SNU475 AMPD1
Mean 0.00992
Standard deviation 0.0075
Values 0.015 0.0046
[83]
THLE AMPD1
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[84]
liver AMPD1
Mean 0
Standard deviation 0
Values 0 0 0 0
[85]
ref_hepatocyte ADSS2
Missing
[86]
HepG2 ADSS2
Missing
[87]
HepG2.C3A ADSS2
Missing
[88]
HuH.7 ADSS2
Missing
[89]
SNU475 ADSS2
Missing
[90]
THLE ADSS2
Missing
[91]
liver ADSS2
Missing