WP_PROXIMAL_TUBULE_TRANSPORT | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | ATP6V0E1 | V-type proton ATPase subunit e 1 | [1] | -1.66[2] | -1.95[3] | -1.66[4] | -0.67[5] | -1.02[6] | -1.54[7] |
2 | SLC3A2 | 4F2 cell-surface antigen heavy chain | [8] | -0.37[9] | -1.08[10] | -0.79[11] | -0.20[12] | 0.47[13] | -2.30[14] |
3 | ATP6V0B | V-type proton ATPase 21 kDa proteolipid subunit | [15] | -1.85[16] | -1.29[17] | -1.69[18] | -1.06[19] | -0.60[20] | -0.96[21] |
4 | ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1 | [22] | 2.05[23] | 1.52[24] | 1.89[25] | 0.90[26] | 1.42[27] | -0.20[28] |
5 | ATP6V0C | V-type proton ATPase 16 kDa proteolipid subunit | [29] | -1.43[30] | -1.49[31] | -1.41[32] | -1.21[33] | -0.32[34] | -1.86[35] |
6 | SLC2A2 | Solute carrier family 2, facilitated glucose transporter member 2 | [36] | -3.52[37] | -2.36[38] | -1.55[39] | -6.12[40] | -10.39[41] | 1.59[42] |
7 | SLC22A7 | Solute carrier family 22 member 7 | [43] | -6.53[44] | -2.77[45] | -5.12[46] | -12.22[47] | [48] | 1.15[49] |
8 | ATP6V1G1 | V-type proton ATPase subunit G 1 | [50] | -1.01[51] | -0.53[52] | -0.58[53] | -0.18[54] | 0.11[55] | -0.85[56] |
9 | ATP1B1 | Sodium/potassium-transporting ATPase subunit beta-1 | [57] | -0.63[58] | 0.18[59] | 0.35[60] | -0.02[61] | -1.20[62] | -1.02[63] |
10 | ATP6V1F | V-type proton ATPase subunit F | [64] | -1.54[65] | -1.35[66] | -1.18[67] | -0.78[68] | -0.61[69] | -2.20[70] |
11 | ATP6V1E1 | V-type proton ATPase subunit E 1 | [71] | -0.74[72] | -0.46[73] | -0.13[74] | 0.55[75] | 0.68[76] | -1.87[77] |
12 | CA2 | Carbonic anhydrase 2 | [78] | -8.49[79] | -8.74[80] | -0.90[81] | -8.85[82] | -6.99[83] | -0.36[84] |
13 | ABCC2 | Canalicular multispecific organic anion transporter 1 | [85] | 0.52[86] | 2.46[87] | 1.04[88] | 0.41[89] | -6.28[90] | 1.70[91] |
14 | SLC47A1 | Multidrug and toxin extrusion protein 1 | [92] | -0.32[93] | -0.06[94] | -0.57[95] | -2.30[96] | -3.55[97] | 0.22[98] |
15 | ATP6V1D | V-type proton ATPase subunit D | [99] | -1.10[100] | -0.91[101] | -1.32[102] | 0.56[103] | 1.08[104] | -1.09[105] |
16 | SLC20A2 | Sodium-dependent phosphate transporter 2 | [106] | -0.33[107] | -0.22[108] | 0.07[109] | -1.76[110] | -2.01[111] | -1.04[112] |
17 | SLC4A2 | Anion exchange protein 2 | [113] | 1.36[114] | 1.00[115] | 2.12[116] | 3.00[117] | 2.17[118] | 0.76[119] |
18 | ABCB1 | Multidrug resistance protein 1 | [120] | -0.90[121] | 1.00[122] | -0.46[123] | -5.20[124] | -6.77[125] | 0.43[126] |
19 | ATP6V1A | V-type proton ATPase catalytic subunit A | [127] | 0.05[128] | 0.75[129] | 1.11[130] | 1.79[131] | 1.67[132] | 1.50[133] |
20 | SLC1A1 | Excitatory amino acid transporter 3 | [134] | -8.90[135] | -8.56[136] | -1.63[137] | -2.08[138] | -2.93[139] | 1.85[140] |
21 | ATP6V1H | V-type proton ATPase subunit H | [141] | -0.63[142] | -0.36[143] | -1.04[144] | 1.28[145] | 1.27[146] | -0.81[147] |
22 | ATP6V1C1 | V-type proton ATPase subunit C 1 | [148] | 0.83[149] | 1.54[150] | 1.88[151] | 2.95[152] | 2.57[153] | 1.07[154] |
23 | SLC12A4 | Solute carrier family 12 member 4 | [155] | 1.38[156] | 2.28[157] | 0.87[158] | 0.66[159] | 1.98[160] | 0.78[161] |
24 | SLC7A9 | b(0,+)-type amino acid transporter 1 | [162] | -3.05[163] | -1.23[164] | -3.09[165] | -7.67[166] | -7.03[167] | -0.62[168] |
25 | SLC13A3 | Solute carrier family 13 member 3 | [169] | 0.00[170] | 1.50[171] | -8.55[172] | -6.70[173] | -1.80[174] | 0.71[175] |
26 | ABCG2 | ATP-binding cassette sub-family G member 2 | [176] | -0.26[177] | 0.01[178] | 1.30[179] | 0.30[180] | -0.71[181] | 0.02[182] |
27 | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1 | [183] | 6.33[184] | 3.72[185] | 2.95[186] | 4.10[187] | 3.33[188] | -1.60[189] |
28 | SLC16A10 | Monocarboxylate transporter 10 | [190] | -1.19[191] | -7.22[192] | 0.56[193] | -5.29[194] | -4.11[195] | 0.29[196] |
29 | SLC26A6 | Solute carrier family 26 member 6 | [197] | 1.79[198] | 3.70[199] | 3.93[200] | 1.12[201] | 2.56[202] | 0.16[203] |
30 | SLC3A1 | Neutral and basic amino acid transport protein rBAT | [204] | -6.72[205] | -5.63[206] | 0.85[207] | -3.37[208] | -7.04[209] | 0.01[210] |
31 | SLC4A4 | Electrogenic sodium bicarbonate cotransporter 1 | [211] | -6.38[212] | -6.01[213] | 1.54[214] | 2.48[215] | -0.05[216] | 3.81[217] |
32 | ABCC4 | Multidrug resistance-associated protein 4 | [218] | 1.48[219] | 0.94[220] | 3.33[221] | 3.35[222] | 2.95[223] | 0.22[224] |
33 | SLC7A7 | Y+L amino acid transporter 1 | [225] | 0.94[226] | -1.80[227] | 3.17[228] | 0.49[229] | 1.64[230] | 0.75[231] |
34 | ATP6V0D2 | V-type proton ATPase subunit d 2 | [232] | -4.60[233] | -4.39[234] | -4.24[235] | -5.30[236] | -2.37[237] | -7.09[238] |
35 | FXYD2 | Sodium/potassium-transporting ATPase subunit gamma | [239] | -0.89[240] | -2.42[241] | [242] | [243] | [244] | -0.42[245] |
36 | SLC7A8 | Large neutral amino acids transporter small subunit 2 | [246] | -3.62[247] | -5.38[248] | -0.42[249] | 1.26[250] | 3.66[251] | 1.91[252] |
37 | SLC6A20 | Sodium- and chloride-dependent transporter XTRP3 | [253] | -2.91[254] | -1.08[255] | -1.05[256] | -1.63[257] | -2.04[258] | -1.66[259] |
38 | AQP1 | Aquaporin-1 | [260] | -5.06[261] | [262] | -1.60[263] | 3.26[264] | -1.07[265] | 4.14[266] |
39 | SLC5A5 | Sodium/iodide cotransporter | [267] | -2.43[268] | -1.21[269] | -0.52[270] | -0.99[271] | -1.52[272] | -2.00[273] |
40 | SLC34A1 | Sodium-dependent phosphate transport protein 2A | [274] | -6.57[275] | -3.91[276] | -0.76[277] | -3.40[278] | [279] | -0.29[280] |
41 | SLC34A3 | Sodium-dependent phosphate transport protein 2C | [281] | 0.72[282] | 3.14[283] | -2.60[284] | -1.39[285] | -1.00[286] | -2.11[287] |
42 | SLC36A2 | Proton-coupled amino acid transporter 2 | [288] | -0.25[289] | 1.41[290] | 1.36[291] | 1.05[292] | 1.23[293] | -0.26[294] |
43 | SLC5A2 | Sodium/glucose cotransporter 2 | [295] | 0.67[296] | 2.23[297] | -1.24[298] | -1.94[299] | -4.42[300] | -0.32[301] |
44 | ATP6V1B1 | V-type proton ATPase subunit B, kidney isoform | [302] | -1.40[303] | 2.46[304] | 2.75[305] | 1.59[306] | 0.12[307] | -2.63[308] |
45 | SLC9A3 | Sodium/hydrogen exchanger 3 | [309] | -0.48[310] | -0.71[311] | 0.50[312] | 1.18[313] | 3.05[314] | -0.69[315] |
46 | SLC22A11 | Solute carrier family 22 member 11 | [316] | 2.20[317] | -0.40[318] | -5.84[319] | -0.11[320] | [321] | -0.92[322] |
47 | SLC5A1 | Sodium/glucose cotransporter 1 | [323] | [324] | [325] | [326] | -1.40[327] | [328] | 6.08[329] |
48 | SLC22A2 | Solute carrier family 22 member 2 | [330] | [331] | -2.66[332] | -2.62[333] | 0.59[334] | -0.01[335] | [336] |
49 | SLC6A19 | Sodium-dependent neutral amino acid transporter B(0)AT1 | [337] | 1.17[338] | -0.14[339] | 7.29[340] | -1.56[341] | -0.69[342] | 5.30[343] |
50 | CLTRN | [344] | [345] | [346] | [347] | [348] | [349] | [350] | |
51 | SLC6A18 | Sodium-dependent neutral amino acid transporter B(0)AT3 | [351] | [352] | [353] | [354] | [355] | [356] | [357] |
52 | ATP6V0A4 | V-type proton ATPase 116 kDa subunit a isoform 4 | [358] | [359] | [360] | [361] | [362] | [363] | [364] |
53 | SLC5A8 | Sodium-coupled monocarboxylate transporter 1 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | MIR6824 | [372] | [373] | [374] | [375] | [376] | [377] | [378] | |
55 | SLC47A2 | Multidrug and toxin extrusion protein 2 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | SLC22A8 | Solute carrier family 22 member 8 | [386] | [387] | [388] | [389] | [390] | [391] | [392] |
57 | CA4 | Carbonic anhydrase 4 | [393] | [394] | [395] | [396] | [397] | [398] | [399] |
58 | SLC22A6 | Solute carrier family 22 member 6 | [400] | [401] | [402] | [403] | [404] | [405] | [406] |