WP_PROTEASOME_DEGRADATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.22[2] | -1.24[3] | -0.96[4] | -1.85[5] | -1.31[6] | -0.71[7] |
2 | UBC | Polyubiquitin-C | [8] | -0.78[9] | -0.49[10] | -0.60[11] | -0.99[12] | -0.93[13] | -0.26[14] |
3 | HLA-A | HLA class I histocompatibility antigen, A-68 alpha chain | [15] | -0.20[16] | 0.23[17] | -5.62[18] | 0.68[19] | -0.27[20] | -0.91[21] |
4 | HLA-C | HLA class I histocompatibility antigen, Cw-17 alpha chain | [22] | -1.05[23] | -1.54[24] | -5.27[25] | -0.10[26] | 0.02[27] | -0.52[28] |
5 | HLA-B | HLA class I histocompatibility antigen, B-73 alpha chain | [29] | -2.02[30] | -3.17[31] | -7.38[32] | 1.33[33] | 0.41[34] | -0.17[35] |
6 | PSME1 | Proteasome activator complex subunit 1 | [36] | -0.55[37] | -2.08[38] | -1.57[39] | -1.71[40] | -2.16[41] | -1.21[42] |
7 | PSME2 | Proteasome activator complex subunit 2 | [43] | -0.37[44] | -1.70[45] | -1.66[46] | -1.50[47] | -1.69[48] | -0.83[49] |
8 | PSMA7 | Proteasome subunit alpha type-7 | [50] | 0.59[51] | 0.76[52] | -0.41[53] | 0.13[54] | -0.22[55] | 0.19[56] |
9 | PSMB1 | Proteasome subunit beta type-1 | [57] | 0.13[58] | 0.32[59] | -0.61[60] | -1.12[61] | -0.26[62] | 0.03[63] |
10 | RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 | 0.67[64] | 0.68[65] | 1.07[66] | 0.05[67] | 0.49[68] | 1.41[69] | |
11 | HLA-E | HLA class I histocompatibility antigen, alpha chain E | [70] | -0.85[71] | -0.82[72] | -1.12[73] | 0.83[74] | -0.46[75] | 1.35[76] |
12 | PSMB3 | Proteasome subunit beta type-3 | [77] | -0.35[78] | -1.07[79] | 0.12[80] | -1.14[81] | -1.16[82] | -0.27[83] |
13 | PSMB4 | Proteasome subunit beta type-4 | [84] | -0.10[85] | 0.13[86] | 0.42[87] | 0.29[88] | 0.38[89] | -0.60[90] |
14 | PSMB7 | Proteasome subunit beta type-7 | [91] | -1.05[92] | -0.97[93] | -0.68[94] | -1.48[95] | -0.95[96] | -1.04[97] |
15 | PSMB5 | Proteasome subunit beta type-5 | [98] | 1.35[99] | -0.01[100] | 0.07[101] | -0.76[102] | -0.39[103] | -0.56[104] |
16 | PSMA6 | Proteasome subunit alpha type-6 | [105] | 1.48[106] | 0.27[107] | 0.36[108] | -0.23[109] | -0.12[110] | -0.48[111] |
17 | PSMA4 | Proteasome subunit alpha type-4 | [112] | -0.45[113] | 0.29[114] | 0.24[115] | 0.07[116] | -0.01[117] | -0.56[118] |
18 | PSMC3 | 26S proteasome regulatory subunit 6A | [119] | -0.48[120] | -0.47[121] | 0.30[122] | -1.13[123] | -0.83[124] | -0.09[125] |
19 | PSMA3 | Proteasome subunit alpha type-3 | [126] | -1.07[127] | 0.01[128] | -0.51[129] | -0.38[130] | -0.73[131] | -0.31[132] |
20 | PSMB6 | Proteasome subunit beta type-6 | [133] | -0.52[134] | -0.30[135] | 0.00[136] | -0.93[137] | -1.10[138] | -0.15[139] |
21 | PSMA2 | Proteasome subunit alpha type-2 | [140] | -0.61[141] | 0.43[142] | 0.92[143] | -0.43[144] | 0.04[145] | 0.07[146] |
22 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [147] | -0.09[148] | 0.00[149] | 0.36[150] | 0.27[151] | -0.17[152] | -0.25[153] |
23 | RPN2 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 | 2.42[154] | 2.51[155] | 2.36[156] | 1.27[157] | 1.19[158] | 1.63[159] | |
24 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [160] | -0.17[161] | 0.28[162] | 0.29[163] | -0.82[164] | -0.24[165] | -0.43[166] |
25 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [167] | -0.01[168] | 0.31[169] | 0.61[170] | -0.54[171] | 0.32[172] | -0.40[173] |
26 | UBE2D3 | Ubiquitin-conjugating enzyme E2 D3 | [174] | 0.15[175] | 0.65[176] | 1.02[177] | 0.19[178] | 0.74[179] | 1.03[180] |
27 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [181] | 1.52[182] | 0.78[183] | 1.01[184] | 0.57[185] | 1.96[186] | 0.63[187] |
28 | PSMC1 | 26S proteasome regulatory subunit 4 | [188] | -0.15[189] | -0.01[190] | -0.50[191] | 0.75[192] | 0.38[193] | -0.21[194] |
29 | PSMA1 | Proteasome subunit alpha type-1 | [195] | 0.03[196] | 0.50[197] | 0.72[198] | 0.33[199] | -0.07[200] | 0.28[201] |
30 | PSMC5 | 26S proteasome regulatory subunit 8 | [202] | 0.35[203] | 0.32[204] | 0.56[205] | -0.26[206] | 0.25[207] | 0.05[208] |
31 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [209] | 0.75[210] | 0.32[211] | 1.07[212] | 0.27[213] | 0.59[214] | -0.24[215] |
32 | PSMB8 | Proteasome subunit beta type-8 | [216] | -1.65[217] | -2.16[218] | -9.22[219] | 0.24[220] | -0.96[221] | -0.92[222] |
33 | PSMC4 | 26S proteasome regulatory subunit 6B | [223] | 0.35[224] | 0.46[225] | 0.55[226] | -0.24[227] | -0.02[228] | 0.10[229] |
34 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [230] | -0.80[231] | -0.24[232] | -1.18[233] | -0.87[234] | 0.05[235] | -0.49[236] |
35 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [237] | 0.39[238] | 0.59[239] | 1.24[240] | 0.19[241] | -0.20[242] | -0.31[243] |
36 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [244] | -0.43[245] | -0.27[246] | -0.42[247] | -0.19[248] | -0.02[249] | -0.38[250] |
37 | PSMC6 | 26S proteasome regulatory subunit 10B | [251] | -0.13[252] | 1.52[253] | 0.50[254] | 0.17[255] | 0.21[256] | 0.27[257] |
38 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [258] | 0.75[259] | 0.44[260] | 1.19[261] | 0.58[262] | 0.84[263] | 1.10[264] |
39 | PSMC2 | 26S proteasome regulatory subunit 7 | [265] | 0.51[266] | 0.99[267] | 0.92[268] | 0.97[269] | 0.90[270] | 1.15[271] |
40 | PSME3 | Proteasome activator complex subunit 3 | [272] | 1.74[273] | 1.53[274] | 1.37[275] | 1.00[276] | 1.37[277] | 0.71[278] |
41 | UBA1 | Ubiquitin-like modifier-activating enzyme 1 | [279] | 2.58[280] | 2.04[281] | 2.37[282] | 2.47[283] | 3.07[284] | 1.57[285] |
42 | UCHL3 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | [286] | -0.41[287] | -0.26[288] | -0.22[289] | -1.26[290] | -1.45[291] | -0.46[292] |
43 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [293] | 1.49[294] | 1.89[295] | 1.93[296] | 1.80[297] | 1.91[298] | 1.90[299] |
44 | PSMB10 | Proteasome subunit beta type-10 | [300] | -1.23[301] | -0.56[302] | -2.29[303] | -0.41[304] | -1.47[305] | -0.25[306] |
45 | PSMA5 | Proteasome subunit alpha type-5 | [307] | 1.82[308] | 2.33[309] | 2.05[310] | 1.86[311] | 1.52[312] | 1.74[313] |
46 | UBE2B | Ubiquitin-conjugating enzyme E2 B | [314] | 0.50[315] | 1.11[316] | 0.50[317] | 0.34[318] | 0.72[319] | 0.45[320] |
47 | PSMB2 | Proteasome subunit beta type-2 | [321] | 1.98[322] | 1.79[323] | 2.34[324] | 2.16[325] | 2.25[326] | 2.23[327] |
48 | PSMB9 | Proteasome subunit beta type-9 | [328] | -2.02[329] | -4.57[330] | -6.72[331] | 1.41[332] | -0.76[333] | -0.67[334] |
49 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [335] | 0.36[336] | 0.93[337] | 0.10[338] | 0.04[339] | 0.58[340] | 0.56[341] |
50 | UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1 | [342] | -4.73[343] | -4.50[344] | 3.49[345] | 3.88[346] | 4.32[347] | -4.46[348] |
51 | UBE2D2 | Ubiquitin-conjugating enzyme E2 D2 | [349] | 1.97[350] | 2.20[351] | 1.61[352] | 1.73[353] | 2.00[354] | 1.13[355] |
52 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [356] | 0.92[357] | 1.32[358] | 1.49[359] | 1.71[360] | 1.13[361] | 0.54[362] |
53 | HLA-F | HLA class I histocompatibility antigen, alpha chain F | [363] | -1.47[364] | -2.75[365] | -6.76[366] | 2.22[367] | 0.42[368] | 1.19[369] |
54 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [370] | 1.33[371] | 0.96[372] | 2.68[373] | 2.09[374] | 2.28[375] | 1.99[376] |
55 | HLA-G | HLA class I histocompatibility antigen, alpha chain G | [377] | -2.04[378] | -2.87[379] | -7.43[380] | -0.39[381] | -6.44[382] | -2.63[383] |
56 | NEDD4 | E3 ubiquitin-protein ligase NEDD4 | [384] | 0.51[385] | 2.77[386] | 3.04[387] | 1.94[388] | 2.27[389] | 3.37[390] |
57 | UBA7 | Ubiquitin-like modifier-activating enzyme 7 | [391] | 0.74[392] | 0.65[393] | -3.98[394] | 2.00[395] | 1.63[396] | 2.55[397] |
58 | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 | [398] | 1.77[399] | 2.82[400] | 3.29[401] | 2.45[402] | 2.29[403] | 1.67[404] |
59 | IFNG | Interferon gamma | [405] | [406] | [407] | [408] | 0.24[409] | [410] | -1.13[411] |
60 | H2AC4 | [412] | [413] | [414] | [415] | [416] | [417] | [418] | |
61 | H2AX | [419] | [420] | [421] | [422] | [423] | [424] | [425] | |
62 | MIR7703 | [426] | [427] | [428] | [429] | [430] | [431] | [432] | |
63 | H2AZ1 | [433] | [434] | [435] | [436] | [437] | [438] | [439] | |
64 | MIR5193 | [440] | [441] | [442] | [443] | [444] | [445] | [446] |