WP_PROGERIAASSOCIATED_LIPODYSTROPHY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 BANF1 Barrier-to-autointegration factor [1] -2.26[2] -2.02[3] -2.40[4] -2.36[5] -2.61[6] -2.32[7]
2 LMNA Prelamin-A/C [8] -0.38[9] -0.80[10] -2.12[11] 0.06[12] -0.83[13] -0.48[14]
3 PARP1 Poly [ADP-ribose] polymerase 1 [15] -0.11[16] -0.23[17] 0.56[18] 0.06[19] -0.53[20] 0.08[21]
4 FNTA Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha -1.14[22] -0.04[23] 0.56[24] -2.08[25] -1.68[26] -0.41[27]
5 ZMPSTE24 CAAX prenyl protease 1 homolog [28] -0.33[29] -0.23[30] -0.15[31] -0.21[32] -0.30[33] 0.75[34]
6 LMNB1 Lamin-B1 [35] 0.74[36] 0.91[37] 1.01[38] 0.85[39] 0.38[40] -1.71[41]
7 ICMT Protein-S-isoprenylcysteine O-methyltransferase [42] 1.71[43] 2.22[44] 1.79[45] 1.32[46] 1.94[47] 1.40[48]
8 SMAD3 Mothers against decapentaplegic homolog 3 [49] 1.69[50] 1.22[51] 1.50[52] 1.33[53] 2.10[54] 0.70[55]
9 LMNB2 Lamin-B2 [56] 3.03[57] 2.53[58] 1.76[59] 1.58[60] 2.27[61] -0.91[62]
10 RECQL ATP-dependent DNA helicase Q1 [63] -1.06[64] 0.14[65] 0.58[66] 0.10[67] 0.62[68] 0.44[69]
11 PPARG Peroxisome proliferator-activated receptor gamma [70] -0.33[71] 1.42[72] 1.98[73] 0.38[74] 0.24[75] 0.11[76]
12 SMAD4 Mothers against decapentaplegic homolog 4 [77] 1.15[78] 1.91[79] 1.93[80] 1.45[81] 1.70[82] 3.28[83]
13 SMAD2 Mothers against decapentaplegic homolog 2 [84] 1.78[85] 2.17[86] 1.72[87] 1.92[88] 2.00[89] 3.06[90]
14 POLD1 DNA polymerase delta catalytic subunit [91] 1.62[92] 1.97[93] 2.85[94] 1.36[95] 2.01[96] 1.16[97]
15 TGFB1 Transforming growth factor beta-1 [98] 3.23[99] 2.32[100] -0.37[101] 3.37[102] 2.49[103] -0.74[104]
16 WRN Werner syndrome ATP-dependent helicase [105] 0.37[106] 1.96[107] 3.95[108] 1.23[109] 0.94[110] 2.46[111]
17 FBN1 Fibrillin-1 [112] 2.82[113] 1.02[114] 3.61[115] 5.87[116] 8.73[117] 7.89[118]
18 KCNJ6 G protein-activated inward rectifier potassium channel 2 [119] [120] [121] [122] 0.34[123] -5.68[124] -1.96[125]
19 FFAR3 Free fatty acid receptor 3 [126] -3.47[127] [128] [129] [130] -3.46[131] [132]
20 MUCL3 [133] [134] [135] [136] [137] [138] [139]
21 SPRTN SprT-like domain-containing protein Spartan [140] [141] [142] [143] [144] [145] [146]
22 INS Insulin [147] [148] [149] [150] [151] [152] [153]
23 MIR7108 [154] [155] [156] [157] [158] [159] [160]
[1]
ref_hepatocyte BANF1
Mean 94
Standard deviation 30
Values 82 77 60 1.3e+02 1.2e+02
[2]
HepG2 BANF1
Mean 51.3
Standard deviation 3.2
Values 54 49
[3]
HepG2.C3A BANF1
Mean 49.2
Standard deviation 10
Values 56 42
[4]
HuH.7 BANF1
Mean 35
Standard deviation 13
Values 47 22 36
[5]
SNU475 BANF1
Mean 46.4
Standard deviation 4.2
Values 43 49
[6]
THLE BANF1
Mean 47.2
Standard deviation 7.6
Values 42 53
[7]
liver BANF1
Mean 19
Standard deviation 19
Values 2 2.4 35 37
[8]
ref_hepatocyte LMNA
Mean 84.6
Standard deviation 77
Values 65 33 42 62 2.2e+02
[9]
HepG2 LMNA
Mean 170
Standard deviation 28
Values 1.5e+02 1.9e+02
[10]
HepG2.C3A LMNA
Mean 103
Standard deviation 24
Values 86 1.2e+02
[11]
HuH.7 LMNA
Mean 38.1
Standard deviation 0.77
Values 37 39 38
[12]
SNU475 LMNA
Mean 223
Standard deviation 30
Values 2e+02 2.4e+02
[13]
THLE LMNA
Mean 146
Standard deviation 49
Values 1.1e+02 1.8e+02
[14]
liver LMNA
Mean 61.5
Standard deviation 29
Values 39 45 59 1e+02
[15]
ref_hepatocyte PARP1
Mean 36.6
Standard deviation 31
Values 33 16 17 26 91
[16]
HepG2 PARP1
Mean 88.3
Standard deviation 6.6
Values 93 84
[17]
HepG2.C3A PARP1
Mean 66.3
Standard deviation 14
Values 76 56
[18]
HuH.7 PARP1
Mean 106
Standard deviation 38
Values 1.3e+02 62 1.3e+02
[19]
SNU475 PARP1
Mean 96.8
Standard deviation 5.2
Values 93 1e+02
[20]
THLE PARP1
Mean 77.5
Standard deviation 13
Values 68 87
[21]
liver PARP1
Mean 39.1
Standard deviation 10
Values 31 44 31 51
[22]
ref_hepatocyte FNTA
Mean 18.3
Standard deviation 3.8
Values 15 15 16 23 22
[23]
HepG2 FNTA
Mean 21.7
Standard deviation 0.34
Values 22 21
[24]
HepG2.C3A FNTA
Mean 37.7
Standard deviation 5.1
Values 34 41
[25]
HuH.7 FNTA
Mean 52.9
Standard deviation 10
Values 50 64 44
[26]
SNU475 FNTA
Mean 11
Standard deviation 2.7
Values 9 13
[27]
THLE FNTA
Mean 17.5
Standard deviation 1.6
Values 19 16
[28]
liver FNTA
Mean 13.9
Standard deviation 5.5
Values 8.1 10 18 19
[29]
ref_hepatocyte ZMPSTE24
Mean 16.5
Standard deviation 7.5
Values 11 12 9.9 23 26
[30]
HepG2 ZMPSTE24
Mean 34.1
Standard deviation 11
Values 42 26
[31]
HepG2.C3A ZMPSTE24
Mean 29.9
Standard deviation 7.9
Values 35 24
[32]
HuH.7 ZMPSTE24
Mean 29
Standard deviation 6.1
Values 29 23 35
[33]
SNU475 ZMPSTE24
Mean 36
Standard deviation 0.34
Values 36 36
[34]
THLE ZMPSTE24
Mean 40.9
Standard deviation 5.6
Values 37 45
[35]
liver ZMPSTE24
Mean 28.1
Standard deviation 4.7
Values 23 31 26 33
[36]
ref_hepatocyte LMNB1
Mean 7.95
Standard deviation 9.7
Values 2.1 3.3 2.1 25 7.4
[37]
HepG2 LMNB1
Mean 34.6
Standard deviation 12
Values 43 26
[38]
HepG2.C3A LMNB1
Mean 31.6
Standard deviation 15
Values 42 21
[39]
HuH.7 LMNB1
Mean 31.5
Standard deviation 13
Values 42 16 36
[40]
SNU475 LMNB1
Mean 36.2
Standard deviation 1.2
Values 35 37
[41]
THLE LMNB1
Mean 31.8
Standard deviation 13
Values 22 41
[42]
liver LMNB1
Mean 2.45
Standard deviation 2.4
Values 3 5.6 0.54 0.69
[43]
ref_hepatocyte ICMT
Mean 7.05
Standard deviation 4.6
Values 3.9 4 5.4 15 7
[44]
HepG2 ICMT
Mean 60.3
Standard deviation 7.3
Values 65 55
[45]
HepG2.C3A ICMT
Mean 69.6
Standard deviation 15
Values 80 59
[46]
HuH.7 ICMT
Mean 47.8
Standard deviation 18
Values 51 29 64
[47]
SNU475 ICMT
Mean 44.4
Standard deviation 3.5
Values 47 42
[48]
THLE ICMT
Mean 82.7
Standard deviation 11
Values 75 91
[49]
liver ICMT
Mean 18.7
Standard deviation 5
Values 23 21 12 20
[50]
ref_hepatocyte SMAD3
Mean 5.99
Standard deviation 4.6
Values 13 2.2 1.9 4.8 8.4
[51]
HepG2 SMAD3
Mean 50.4
Standard deviation 14
Values 40 60
[52]
HepG2.C3A SMAD3
Mean 29.5
Standard deviation 11
Values 22 37
[53]
HuH.7 SMAD3
Mean 33.2
Standard deviation 6.9
Values 28 41 31
[54]
SNU475 SMAD3
Mean 38.2
Standard deviation 2.7
Values 36 40
[55]
THLE SMAD3
Mean 78.9
Standard deviation 8.4
Values 73 85
[56]
liver SMAD3
Mean 9.85
Standard deviation 3
Values 13 7.4 12 7.1
[57]
ref_hepatocyte LMNB2
Mean 5.9
Standard deviation 5.7
Values 6.2 0.9 1.5 15 5.6
[58]
HepG2 LMNB2
Mean 126
Standard deviation 7.2
Values 1.2e+02 1.3e+02
[59]
HepG2.C3A LMNB2
Mean 72.2
Standard deviation 8
Values 78 67
[60]
HuH.7 LMNB2
Mean 39.2
Standard deviation 17
Values 48 20 50
[61]
SNU475 LMNB2
Mean 44.6
Standard deviation 0.24
Values 44 45
[62]
THLE LMNB2
Mean 87
Standard deviation 20
Values 73 1e+02
[63]
liver LMNB2
Mean 3.16
Standard deviation 2
Values 4.5 5.3 1.1 1.9
[64]
ref_hepatocyte RECQL
Mean 5.42
Standard deviation 4.7
Values 3 1.4 2.7 7.2 13
[65]
HepG2 RECQL
Mean 6.79
Standard deviation 3.5
Values 9.3 4.3
[66]
HepG2.C3A RECQL
Mean 12.7
Standard deviation 8.9
Values 19 6.4
[67]
HuH.7 RECQL
Mean 15.9
Standard deviation 3.3
Values 16 13 19
[68]
SNU475 RECQL
Mean 14.8
Standard deviation 0.64
Values 15 14
[69]
THLE RECQL
Mean 25.6
Standard deviation 1.3
Values 25 26
[70]
liver RECQL
Mean 7.45
Standard deviation 2.3
Values 6 10 5.1 8.2
[71]
ref_hepatocyte PPARG
Mean 3.66
Standard deviation 0.37
Values 3.1 3.9 3.6 3.6 4.1
[72]
HepG2 PPARG
Mean 7.61
Standard deviation 0.54
Values 7.2 8
[73]
HepG2.C3A PPARG
Mean 20.7
Standard deviation 6.8
Values 16 26
[74]
HuH.7 PPARG
Mean 28.4
Standard deviation 6.2
Values 26 35 24
[75]
SNU475 PPARG
Mean 12.1
Standard deviation 2.4
Values 14 10
[76]
THLE PPARG
Mean 13.2
Standard deviation 1.2
Values 12 14
[77]
liver PPARG
Mean 4
Standard deviation 1.3
Values 2.5 4 3.8 5.7
[78]
ref_hepatocyte SMAD4
Mean 3.16
Standard deviation 0.71
Values 4.2 3.4 2.4 2.9 2.8
[79]
HepG2 SMAD4
Mean 18.3
Standard deviation 3.2
Values 21 16
[80]
HepG2.C3A SMAD4
Mean 25.2
Standard deviation 3
Values 23 27
[81]
HuH.7 SMAD4
Mean 23.6
Standard deviation 3.4
Values 20 27 24
[82]
SNU475 SMAD4
Mean 21.8
Standard deviation 2.7
Values 20 24
[83]
THLE SMAD4
Mean 31.4
Standard deviation 1.4
Values 30 32
[84]
liver SMAD4
Mean 31
Standard deviation 13
Values 44 40 23 16
[85]
ref_hepatocyte SMAD2
Mean 2.54
Standard deviation 1.2
Values 1.9 1.6 1.9 4.5 2.8
[86]
HepG2 SMAD2
Mean 22.7
Standard deviation 2.3
Values 24 21
[87]
HepG2.C3A SMAD2
Mean 24.2
Standard deviation 1.1
Values 23 25
[88]
HuH.7 SMAD2
Mean 16.4
Standard deviation 1.6
Values 15 18 17
[89]
SNU475 SMAD2
Mean 24.3
Standard deviation 3.3
Values 22 27
[90]
THLE SMAD2
Mean 31
Standard deviation 0.65
Values 31 32
[91]
liver SMAD2
Mean 21.4
Standard deviation 6.7
Values 25 29 17 15
[92]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2.7 1.4 2.4 2 3.5
[93]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 18 21
[94]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 22 18
[95]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 44 16 42
[96]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 18 14
[97]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[98]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 5.1 4.7 6.2 5.8
[99]
ref_hepatocyte TGFB1
Mean 2.22
Standard deviation 1.8
Values 0.92 2.3 1.3 5.3 1.3
[100]
HepG2 TGFB1
Mean 54.4
Standard deviation 32
Values 32 77
[101]
HepG2.C3A TGFB1
Mean 23.6
Standard deviation 8.3
Values 18 29
[102]
HuH.7 TGFB1
Mean 3.37
Standard deviation 1.4
Values 3.7 1.8 4.5
[103]
SNU475 TGFB1
Mean 58.3
Standard deviation 7.8
Values 53 64
[104]
THLE TGFB1
Mean 38.3
Standard deviation 9.8
Values 31 45
[105]
liver TGFB1
Mean 1.34
Standard deviation 0.71
Values 2.3 1.4 1.1 0.62
[106]
ref_hepatocyte WRN
Mean 1.33
Standard deviation 0.66
Values 1.8 0.54 0.68 1.8 1.8
[107]
HepG2 WRN
Mean 4.47
Standard deviation 1.6
Values 5.6 3.3
[108]
HepG2.C3A WRN
Mean 11
Standard deviation 2.1
Values 12 9.5
[109]
HuH.7 WRN
Mean 40.4
Standard deviation 6.8
Values 33 46 43
[110]
SNU475 WRN
Mean 7.93
Standard deviation 0.72
Values 7.4 8.4
[111]
THLE WRN
Mean 7.81
Standard deviation 1.9
Values 9.2 6.5
[112]
liver WRN
Mean 7.39
Standard deviation 3.4
Values 10 10 4.3 4.7
[113]
ref_hepatocyte FBN1
Mean 0.0913
Standard deviation 0.079
Values 0.043 0.081 0.052 0.23 0.049
[114]
HepG2 FBN1
Mean 1.68
Standard deviation 0.54
Values 2.1 1.3
[115]
HepG2.C3A FBN1
Mean 0.392
Standard deviation 0.0088
Values 0.39 0.4
[116]
HuH.7 FBN1
Mean 2.19
Standard deviation 0.46
Values 1.7 2.3 2.6
[117]
SNU475 FBN1
Mean 13.6
Standard deviation 5
Values 17 10
[118]
THLE FBN1
Mean 119
Standard deviation 48
Values 85 1.5e+02
[119]
liver FBN1
Mean 21.8
Standard deviation 19
Values 34 42 3.5 8.1
[120]
ref_hepatocyte KCNJ6
Mean 0.0496
Standard deviation 0.081
Values 0.19 0 0.06 0 0
[121]
HepG2 KCNJ6
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A KCNJ6
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 KCNJ6
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 KCNJ6
Mean 0.159
Standard deviation 0.048
Values 0.19 0.13
[125]
THLE KCNJ6
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[126]
liver KCNJ6
Mean 0.0128
Standard deviation 0.026
Values 0 0 0 0.051
[127]
ref_hepatocyte FFAR3
Mean 0.0488
Standard deviation 0.11
Values 0 0.24 0 0 0
[128]
HepG2 FFAR3
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[129]
HepG2.C3A FFAR3
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 FFAR3
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 FFAR3
Mean 0
Standard deviation 0
Values 0 0
[132]
THLE FFAR3
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[133]
liver FFAR3
Mean 0
Standard deviation 0
Values 0 0 0 0
[134]
ref_hepatocyte MUCL3
Missing
[135]
HepG2 MUCL3
Missing
[136]
HepG2.C3A MUCL3
Missing
[137]
HuH.7 MUCL3
Missing
[138]
SNU475 MUCL3
Missing
[139]
THLE MUCL3
Missing
[140]
liver MUCL3
Missing
[141]
ref_hepatocyte SPRTN
Missing
[142]
HepG2 SPRTN
Mean 4.98
Standard deviation 0.34
Values 5.2 4.7
[143]
HepG2.C3A SPRTN
Mean 4.92
Standard deviation 1.9
Values 6.2 3.6
[144]
HuH.7 SPRTN
Mean 6.97
Standard deviation 1.2
Values 7.1 5.7 8.1
[145]
SNU475 SPRTN
Mean 9.18
Standard deviation 0.11
Values 9.1 9.3
[146]
THLE SPRTN
Mean 8.18
Standard deviation 0.24
Values 8 8.4
[147]
liver SPRTN
Mean 5.28
Standard deviation 0.37
Values 5.4 5.1 4.9 5.8
[148]
ref_hepatocyte INS
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 INS
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[150]
HepG2.C3A INS
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 INS
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 INS
Mean 0
Standard deviation 0
Values 0 0
[153]
THLE INS
Mean 0
Standard deviation 0
Values 0 0
[154]
liver INS
Mean 0.0838
Standard deviation 0.13
Values 0.28 0.057 0 0
[155]
ref_hepatocyte MIR7108
Missing
[156]
HepG2 MIR7108
Missing
[157]
HepG2.C3A MIR7108
Missing
[158]
HuH.7 MIR7108
Missing
[159]
SNU475 MIR7108
Missing
[160]
THLE MIR7108
Missing
[161]
liver MIR7108
Missing