WP_PREGNANE_X_RECEPTOR_PATHWAY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HSP90AA1 Heat shock protein HSP 90-alpha [1] 1.63[2] 1.82[3] 1.77[4] 2.14[5] 2.24[6] -1.53[7]
2 CYP2C9 Cytochrome P450 2C9 [8] [9] -15.18[10] -7.56[11] -14.15[12] -12.94[13] 0.75[14]
3 SULT2A1 Bile salt sulfotransferase [15] -1.00[16] -0.85[17] -1.40[18] -10.55[19] -9.95[20] 0.02[21]
4 CYP3A4 Cytochrome P450 3A4 [22] -9.47[23] -10.37[24] -11.37[25] -14.46[26] -12.51[27] 0.46[28]
5 UGT1A6 UDP-glucuronosyltransferase 1-6 [29] -6.56[30] -15.08[31] -8.48[32] -5.81[33] -11.24[34] -4.16[35]
6 CYP2A6 Cytochrome P450 2A6 [36] -15.58[37] [38] -7.81[39] -11.22[40] -13.25[41] -1.89[42]
7 GSTA2 Glutathione S-transferase A2 [43] -4.47[44] -7.75[45] -2.63[46] -7.39[47] -10.53[48] -3.70[49]
8 CYP3A5 Cytochrome P450 3A5 [50] -4.54[51] -3.09[52] -5.12[53] -7.03[54] -8.85[55] 0.82[56]
9 UGT1A1 UDP-glucuronosyltransferase 1-1 [57] -4.09[58] -11.13[59] -5.25[60] -0.29[61] -9.88[62] -0.32[63]
10 PSMC5 26S proteasome regulatory subunit 8 [64] 1.65[65] 0.67[66] 1.48[67] 0.86[68] 1.70[69] -1.39[70]
11 UGT1A4 UDP-glucuronosyltransferase 1-4 [71] -11.47[72] [73] -11.15[74] -9.57[75] [76] -0.13[77]
12 CYP2B6 Cytochrome P450 2B6 [78] -7.36[79] -4.71[80] -2.63[81] -9.01[82] -9.61[83] 2.13[84]
13 SLCO1B1 Solute carrier organic anion transporter family member 1B1 [85] -12.90[86] -9.89[87] -3.95[88] -10.29[89] [90] 1.30[91]
14 DNAJC7 DnaJ homolog subfamily C member 7 [92] 1.71[93] 0.17[94] 1.75[95] 0.84[96] 1.62[97] -2.28[98]
15 ABCC2 Canalicular multispecific organic anion transporter 1 [99] 3.11[100] 3.90[101] 3.03[102] 1.81[103] -4.57[104] 1.68[105]
16 CYP3A7 Cytochrome P450 3A7 [106] -4.65[107] -3.16[108] -7.18[109] [110] -10.31[111] -1.94[112]
17 CYP2C19 Cytochrome P450 2C19 [113] [114] [115] -4.71[116] -11.84[117] -11.24[118] 1.31[119]
18 UGT1A9 UDP-glucuronosyltransferase 1-9 [120] -5.43[121] -11.09[122] -6.56[123] -4.62[124] -9.47[125] -0.91[126]
19 RXRA Retinoic acid receptor RXR-alpha [127] 2.22[128] 1.24[129] 2.80[130] 2.07[131] 2.14[132] 1.88[133]
20 ABCC3 Canalicular multispecific organic anion transporter 2 [134] 3.36[135] 1.90[136] 0.98[137] 2.32[138] 2.14[139] 2.37[140]
21 ABCB1 Multidrug resistance protein 1 [141] 1.69[142] 2.43[143] 1.52[144] -3.80[145] -5.06[146] 0.41[147]
22 NR1I2 Nuclear receptor subfamily 1 group I member 2 [148] 0.89[149] -0.14[150] -3.96[151] -7.97[152] -6.61[153] 1.41[154]
23 CYP4F12 Cytochrome P450 4F12 [155] -0.43[156] 0.13[157] 2.02[158] -2.89[159] -6.53[160] -0.08[161]
24 UGT1A3 UDP-glucuronosyltransferase 1-3 [162] -0.69[163] [164] -7.41[165] -4.36[166] -9.07[167] 0.97[168]
25 SRC Proto-oncogene tyrosine-protein kinase Src [169] 5.30[170] 4.51[171] 4.22[172] 4.45[173] 4.04[174] -1.12[175]
26 NRIP1 Nuclear receptor-interacting protein 1 [176] 3.88[177] 4.40[178] 3.86[179] 4.98[180] 4.59[181] 2.34[182]
27 NCOA3 Nuclear receptor coactivator 3 [183] 4.99[184] 3.62[185] 4.64[186] 5.16[187] 4.51[188] 2.38[189]
28 NCOA1 Nuclear receptor coactivator 1 [190] 2.74[191] 2.53[192] 3.44[193] 3.85[194] 3.70[195] 2.38[196]
29 PPARGC1A Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 1.19[197] 3.30[198] -6.77[199] 2.82[200] -0.08[201] 3.16[202]
30 SRPX2 Sushi repeat-containing protein SRPX2 [203] 1.30[204] 1.22[205] -2.24[206] 2.55[207] 2.83[208] -0.07[209]
31 FOXO1 Forkhead box protein O1 [210] 3.97[211] 2.86[212] 3.71[213] 3.23[214] 5.65[215] 2.81[216]
32 ABCC4 Multidrug resistance-associated protein 4 [217] 4.07[218] 2.37[219] 5.32[220] 4.75[221] 4.66[222] 0.20[223]
33 NCOA2 Nuclear receptor coactivator 2 [224] 3.85[225] 3.89[226] 6.43[227] 5.25[228] 3.95[229] 4.33[230]
[1]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 1.3e+02 1.7e+02 2.5e+02 5.4e+02 6.9e+02
[2]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 6.9e+02 3.2e+02
[3]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 1.2e+03 5.1e+02
[4]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[5]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 8e+02 5.9e+02
[6]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[7]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 1.6e+02 1.9e+02 2.7e+02 2.4e+02
[8]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 21 9.2e+02 4.7e+02 0.064 20
[9]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[10]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[11]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[12]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[13]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[14]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 2.9e+02 6.1e+02 8.6e+02 1.5e+03
[15]
ref_hepatocyte SULT2A1
Mean 281
Standard deviation 2.8e+02
Values 7.2 3e+02 6.4e+02 4.5e+02 5.2
[16]
HepG2 SULT2A1
Mean 64.4
Standard deviation 29
Values 85 44
[17]
HepG2.C3A SULT2A1
Mean 109
Standard deviation 37
Values 83 1.4e+02
[18]
HuH.7 SULT2A1
Mean 43.5
Standard deviation 18
Values 38 64 29
[19]
SNU475 SULT2A1
Mean 0.0827
Standard deviation 0.012
Values 0.091 0.074
[20]
THLE SULT2A1
Mean 0.106
Standard deviation 0.0079
Values 0.1 0.11
[21]
liver SULT2A1
Mean 489
Standard deviation 2.7e+02
Values 2.3e+02 2.9e+02 8.1e+02 6.3e+02
[22]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 11 9.6e+02 3.2e+02 0.24 11
[23]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.24 0.097
[24]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.2 0.068
[25]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.047 0.064 0.0082
[26]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[27]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[28]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 49 6.4e+02 4.3e+02 1.3e+03
[29]
ref_hepatocyte UGT1A6
Mean 242
Standard deviation 2.6e+02
Values 11 5.9e+02 4.3e+02 0.45 1.7e+02
[30]
HepG2 UGT1A6
Mean 1.17
Standard deviation 0.86
Values 0.56 1.8
[31]
HepG2.C3A UGT1A6
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[32]
HuH.7 UGT1A6
Mean 0.277
Standard deviation 0.33
Values 0.14 0.65 0.041
[33]
SNU475 UGT1A6
Mean 1.9
Standard deviation 0.11
Values 1.8 2
[34]
THLE UGT1A6
Mean 0.0372
Standard deviation 0.053
Values 0 0.074
[35]
liver UGT1A6
Mean 23.2
Standard deviation 17
Values 8.2 34 9 42
[36]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 38 5.5e+02 5.6e+02 0 4.6
[37]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[38]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.12 1 0.11
[40]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.025 0.06
[41]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[42]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 13 1.8e+02 29 2.1e+02
[43]
ref_hepatocyte GSTA2
Mean 199
Standard deviation 3.4e+02
Values 1.1 8e+02 1.2e+02 27 48
[44]
HepG2 GSTA2
Mean 4.11
Standard deviation 1.5
Values 5.2 3.1
[45]
HepG2.C3A GSTA2
Mean 0.647
Standard deviation 0.13
Values 0.74 0.55
[46]
HuH.7 GSTA2
Mean 13.1
Standard deviation 7.6
Values 10 22 7.6
[47]
SNU475 GSTA2
Mean 0.525
Standard deviation 0.65
Values 0.066 0.98
[48]
THLE GSTA2
Mean 0.0506
Standard deviation 0.0038
Values 0.053 0.048
[49]
liver GSTA2
Mean 26.3
Standard deviation 39
Values 0.29 20 0.73 84
[50]
ref_hepatocyte CYP3A5
Mean 139
Standard deviation 1.6e+02
Values 35 3.9e+02 2e+02 22 55
[51]
HepG2 CYP3A5
Mean 2.75
Standard deviation 2.1
Values 4.2 1.3
[52]
HepG2.C3A CYP3A5
Mean 11.4
Standard deviation 3.8
Values 8.7 14
[53]
HuH.7 CYP3A5
Mean 1.63
Standard deviation 1.6
Values 0.83 3.5 0.58
[54]
SNU475 CYP3A5
Mean 0.471
Standard deviation 0.12
Values 0.39 0.56
[55]
THLE CYP3A5
Mean 0.113
Standard deviation 0.032
Values 0.14 0.09
[56]
liver CYP3A5
Mean 424
Standard deviation 3.2e+02
Values 2.8e+02 2.7e+02 9e+02 2.5e+02
[57]
ref_hepatocyte UGT1A1
Mean 67.2
Standard deviation 89
Values 15 96 2.1e+02 0.52 12
[58]
HepG2 UGT1A1
Mean 1.8
Standard deviation 0.2
Values 1.7 1.9
[59]
HepG2.C3A UGT1A1
Mean 0.0209
Standard deviation 0.016
Values 0.032 0.0097
[60]
HuH.7 UGT1A1
Mean 0.72
Standard deviation 0.5
Values 0.31 1.3 0.57
[61]
SNU475 UGT1A1
Mean 24.4
Standard deviation 21
Values 9.8 39
[62]
THLE UGT1A1
Mean 0.0266
Standard deviation 0.038
Values 0 0.053
[63]
liver UGT1A1
Mean 92.4
Standard deviation 46
Values 34 83 1.1e+02 1.4e+02
[64]
ref_hepatocyte PSMC5
Mean 54.8
Standard deviation 9.1
Values 54 55 65 41 60
[65]
HepG2 PSMC5
Mean 78.5
Standard deviation 1.9
Values 77 80
[66]
HepG2.C3A PSMC5
Mean 60.6
Standard deviation 6.4
Values 65 56
[67]
HuH.7 PSMC5
Mean 62.2
Standard deviation 21
Values 78 38 70
[68]
SNU475 PSMC5
Mean 43.9
Standard deviation 8.5
Values 50 38
[69]
THLE PSMC5
Mean 66.7
Standard deviation 5.2
Values 63 70
[70]
liver PSMC5
Mean 35.8
Standard deviation 27
Values 11 14 56 62
[71]
ref_hepatocyte UGT1A4
Mean 53.1
Standard deviation 73
Values 2.5 1.6e+02 99 0 4.2
[72]
HepG2 UGT1A4
Mean 0.00858
Standard deviation 0.012
Values 0.017 0
[73]
HepG2.C3A UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 UGT1A4
Mean 0.00954
Standard deviation 0.0096
Values 0.0094 0.019 0
[75]
SNU475 UGT1A4
Mean 0.031
Standard deviation 0.015
Values 0.02 0.042
[76]
THLE UGT1A4
Mean 0
Standard deviation 0
Values 0 0
[77]
liver UGT1A4
Mean 83.1
Standard deviation 65
Values 32 95 36 1.7e+02
[78]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 12 1e+02 1.3e+02 0 4.1
[79]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.034 0.24
[80]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 0.92 1.7
[81]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 1.9 5.9 2.1
[82]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.071 0.014
[83]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[84]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 7.4 3.2e+02 23 1.1e+03
[85]
ref_hepatocyte SLCO1B1
Mean 35.9
Standard deviation 41
Values 1.4 1e+02 37 0 40
[86]
HepG2 SLCO1B1
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[87]
HepG2.C3A SLCO1B1
Mean 0.0263
Standard deviation 0.023
Values 0.043 0.0097
[88]
HuH.7 SLCO1B1
Mean 0.948
Standard deviation 1.4
Values 0.22 2.6 0.074
[89]
SNU475 SLCO1B1
Mean 0.0127
Standard deviation 0.018
Values 0.025 0
[90]
THLE SLCO1B1
Mean 0
Standard deviation 0
Values 0 0
[91]
liver SLCO1B1
Mean 152
Standard deviation 42
Values 95 1.8e+02 1.8e+02 1.5e+02
[92]
ref_hepatocyte DNAJC7
Mean 31.8
Standard deviation 12
Values 23 19 29 43 45
[93]
HepG2 DNAJC7
Mean 47.6
Standard deviation 7.8
Values 53 42
[94]
HepG2.C3A DNAJC7
Mean 24.9
Standard deviation 2.6
Values 27 23
[95]
HuH.7 DNAJC7
Mean 43.7
Standard deviation 8.3
Values 50 34 46
[96]
SNU475 DNAJC7
Mean 25.2
Standard deviation 1
Values 26 24
[97]
THLE DNAJC7
Mean 36.5
Standard deviation 4.3
Values 33 40
[98]
liver DNAJC7
Mean 11.3
Standard deviation 2
Values 8.4 12 12 13
[99]
ref_hepatocyte ABCC2
Mean 31.6
Standard deviation 23
Values 16 17 17 68 40
[100]
HepG2 ABCC2
Mean 125
Standard deviation 1.3
Values 1.3e+02 1.2e+02
[101]
HepG2.C3A ABCC2
Mean 328
Standard deviation 1.2
Values 3.3e+02 3.3e+02
[102]
HuH.7 ABCC2
Mean 105
Standard deviation 48
Values 68 1.6e+02 88
[103]
SNU475 ABCC2
Mean 48.9
Standard deviation 12
Values 41 57
[104]
THLE ABCC2
Mean 0.497
Standard deviation 0.041
Values 0.53 0.47
[105]
liver ABCC2
Mean 174
Standard deviation 96
Values 1.9e+02 3e+02 89 1.1e+02
[106]
ref_hepatocyte CYP3A7
Mean 29.1
Standard deviation 41
Values 5 32 1e+02 8.7 0.12
[107]
HepG2 CYP3A7
Mean 0.531
Standard deviation 0.38
Values 0.8 0.26
[108]
HepG2.C3A CYP3A7
Mean 2.26
Standard deviation 0.013
Values 2.3 2.3
[109]
HuH.7 CYP3A7
Mean 0.0822
Standard deviation 0.074
Values 0.047 0.17 0.033
[110]
SNU475 CYP3A7
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE CYP3A7
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[112]
liver CYP3A7
Mean 13
Standard deviation 12
Values 5.1 5.2 30 11
[113]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 72 18 0 5.9
[114]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.2 0.6 0.098
[117]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[118]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[119]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 38 92 65 1.3e+02
[120]
ref_hepatocyte UGT1A9
Mean 15.2
Standard deviation 13
Values 2.6 27 26 0 21
[121]
HepG2 UGT1A9
Mean 0.16
Standard deviation 0.057
Values 0.12 0.2
[122]
HepG2.C3A UGT1A9
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[123]
HuH.7 UGT1A9
Mean 0.0656
Standard deviation 0.056
Values 0.0094 0.12 0.066
[124]
SNU475 UGT1A9
Mean 0.273
Standard deviation 0.34
Values 0.03 0.51
[125]
THLE UGT1A9
Mean 0.00798
Standard deviation 0.011
Values 0 0.016
[126]
liver UGT1A9
Mean 13.9
Standard deviation 9.6
Values 3 22 8.7 22
[127]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 9.4 18 22 15 7.5
[128]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 29 33
[129]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 20 28
[130]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 30 51 42
[131]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 21 33
[132]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[133]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.2e+02 72 1.3e+02 49
[134]
ref_hepatocyte ABCC3
Mean 14.4
Standard deviation 9.9
Values 5 9.7 31 14 12
[135]
HepG2 ABCC3
Mean 67.6
Standard deviation 20
Values 54 81
[136]
HepG2.C3A ABCC3
Mean 37.4
Standard deviation 7.2
Values 32 42
[137]
HuH.7 ABCC3
Mean 11.6
Standard deviation 4.6
Values 10 17 7.9
[138]
SNU475 ABCC3
Mean 31.8
Standard deviation 16
Values 21 43
[139]
THLE ABCC3
Mean 23.7
Standard deviation 5.8
Values 28 20
[140]
liver ABCC3
Mean 128
Standard deviation 23
Values 1.3e+02 1.4e+02 93 1.5e+02
[141]
ref_hepatocyte ABCB1
Mean 12.8
Standard deviation 7
Values 15 5.6 5.4 17 21
[142]
HepG2 ABCB1
Mean 18.8
Standard deviation 3.2
Values 21 17
[143]
HepG2.C3A ABCB1
Mean 47.9
Standard deviation 1.3
Values 49 47
[144]
HuH.7 ABCB1
Mean 15
Standard deviation 8.7
Values 9 25 11
[145]
SNU475 ABCB1
Mean 0.405
Standard deviation 0.094
Values 0.47 0.34
[146]
THLE ABCB1
Mean 0.143
Standard deviation 0.0068
Values 0.15 0.14
[147]
liver ABCB1
Mean 29
Standard deviation 14
Values 31 46 13 26
[148]
ref_hepatocyte NR1I2
Mean 9.56
Standard deviation 6.3
Values 6.4 18 15 5.2 3.7
[149]
HepG2 NR1I2
Mean 8.09
Standard deviation 2.1
Values 9.6 6.6
[150]
HepG2.C3A NR1I2
Mean 6.05
Standard deviation 2.4
Values 7.8 4.3
[151]
HuH.7 NR1I2
Mean 0.251
Standard deviation 0.064
Values 0.23 0.32 0.2
[152]
SNU475 NR1I2
Mean 0.0169
Standard deviation 0.0024
Values 0.015 0.019
[153]
THLE NR1I2
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[154]
liver NR1I2
Mean 43.7
Standard deviation 13
Values 38 37 63 37
[155]
ref_hepatocyte CYP4F12
Mean 7.85
Standard deviation 7.8
Values 0.73 19 8.4 11 0.13
[156]
HepG2 CYP4F12
Mean 2.67
Standard deviation 0.39
Values 2.4 2.9
[157]
HepG2.C3A CYP4F12
Mean 5.98
Standard deviation 2.1
Values 4.5 7.5
[158]
HuH.7 CYP4F12
Mean 13
Standard deviation 3.4
Values 14 16 9.3
[159]
SNU475 CYP4F12
Mean 0.47
Standard deviation 0.47
Values 0.14 0.8
[160]
THLE CYP4F12
Mean 0.0316
Standard deviation 0.022
Values 0.047 0.016
[161]
liver CYP4F12
Mean 12.8
Standard deviation 14
Values 3.9 5.3 34 8.3
[162]
ref_hepatocyte UGT1A3
Mean 4.24
Standard deviation 4.8
Values 0.37 11 7.9 0 2.3
[163]
HepG2 UGT1A3
Mean 1.2
Standard deviation 0.2
Values 1.1 1.3
[164]
HepG2.C3A UGT1A3
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 UGT1A3
Mean 0.0101
Standard deviation 0.0024
Values 0.0094 0.013 0.0082
[166]
SNU475 UGT1A3
Mean 0.0911
Standard deviation 0.029
Values 0.071 0.11
[167]
THLE UGT1A3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[168]
liver UGT1A3
Mean 14.2
Standard deviation 12
Values 5.8 21 2.5 28
[169]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 2.2 1.2 0.77 9.6 4.7
[170]
HepG2 SRC
Mean 66
Standard deviation 21
Values 51 81
[171]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 45 71
[172]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 26 29 28
[173]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 33 38
[174]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[175]
liver SRC
Mean 2.9
Standard deviation 1
Values 3.2 2.5 4.1 1.7
[176]
ref_hepatocyte NRIP1
Mean 3.23
Standard deviation 1.9
Values 3 2.2 1.5 6.5 2.9
[177]
HepG2 NRIP1
Mean 21.8
Standard deviation 7
Values 27 17
[178]
HepG2.C3A NRIP1
Mean 47.3
Standard deviation 8.4
Values 53 41
[179]
HuH.7 NRIP1
Mean 19.2
Standard deviation 8.7
Values 12 29 17
[180]
SNU475 NRIP1
Mean 45.2
Standard deviation 4.6
Values 48 42
[181]
THLE NRIP1
Mean 29
Standard deviation 7.8
Values 35 23
[182]
liver NRIP1
Mean 28
Standard deviation 18
Values 44 43 15 11
[183]
ref_hepatocyte NCOA3
Mean 2.66
Standard deviation 1.4
Values 4.1 1.3 1.7 4.2 2
[184]
HepG2 NCOA3
Mean 38.6
Standard deviation 12
Values 47 30
[185]
HepG2.C3A NCOA3
Mean 22.8
Standard deviation 0.64
Values 23 22
[186]
HuH.7 NCOA3
Mean 27
Standard deviation 8
Values 18 33 30
[187]
SNU475 NCOA3
Mean 41.9
Standard deviation 0.54
Values 42 42
[188]
THLE NCOA3
Mean 22.7
Standard deviation 0.25
Values 23 23
[189]
liver NCOA3
Mean 23.7
Standard deviation 5.8
Values 28 29 20 18
[190]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.1 2.8 2.8 1.8 2
[191]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 7.4 5.4
[192]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 9 7.9
[193]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 6.6 12 9.2
[194]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 13 14
[195]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[196]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 22 23 17 13
[197]
ref_hepatocyte PPARGC1A
Mean 1.87
Standard deviation 1.7
Values 0.25 1.6 3.2 4 0.26
[198]
HepG2 PPARGC1A
Mean 1.94
Standard deviation 0.37
Values 2.2 1.7
[199]
HepG2.C3A PPARGC1A
Mean 12.8
Standard deviation 3.6
Values 10 15
[200]
HuH.7 PPARGC1A
Mean 0.00701
Standard deviation 0.0065
Values 0 0.013 0.0082
[201]
SNU475 PPARGC1A
Mean 5.83
Standard deviation 1.4
Values 4.9 6.8
[202]
THLE PPARGC1A
Mean 0.662
Standard deviation 0.1
Values 0.73 0.59
[203]
liver PPARGC1A
Mean 28.7
Standard deviation 18
Values 26 54 20 15
[204]
ref_hepatocyte SRPX2
Mean 1.81
Standard deviation 2.7
Values 1.7 0.22 0.59 0.11 6.4
[205]
HepG2 SRPX2
Mean 2.04
Standard deviation 0.11
Values 2 2.1
[206]
HepG2.C3A SRPX2
Mean 2.94
Standard deviation 1.9
Values 4.3 1.6
[207]
HuH.7 SRPX2
Mean 0.156
Standard deviation 0.078
Values 0.15 0.24 0.082
[208]
SNU475 SRPX2
Mean 4.68
Standard deviation 1.6
Values 5.8 3.5
[209]
THLE SRPX2
Mean 4.8
Standard deviation 0.79
Values 4.2 5.4
[210]
liver SRPX2
Mean 2.97
Standard deviation 0.43
Values 3 2.4 3.4 3.1
[211]
ref_hepatocyte FOXO1
Mean 1.77
Standard deviation 0.68
Values 2 2.6 1.9 0.71 1.7
[212]
HepG2 FOXO1
Mean 12.6
Standard deviation 1.8
Values 14 11
[213]
HepG2.C3A FOXO1
Mean 8.92
Standard deviation 1.5
Values 7.9 10
[214]
HuH.7 FOXO1
Mean 9.41
Standard deviation 1.6
Values 7.6 10 10
[215]
SNU475 FOXO1
Mean 7.33
Standard deviation 1.8
Values 6 8.6
[216]
THLE FOXO1
Mean 33.2
Standard deviation 1.9
Values 32 35
[217]
liver FOXO1
Mean 21.4
Standard deviation 7
Values 29 19 25 13
[218]
ref_hepatocyte ABCC4
Mean 1.25
Standard deviation 1.2
Values 0.52 0.16 0.41 2.7 2.4
[219]
HepG2 ABCC4
Mean 9.57
Standard deviation 0.89
Values 8.9 10
[220]
HepG2.C3A ABCC4
Mean 4.52
Standard deviation 0.047
Values 4.5 4.5
[221]
HuH.7 ABCC4
Mean 20.4
Standard deviation 3.5
Values 16 23 22
[222]
SNU475 ABCC4
Mean 14.9
Standard deviation 1.9
Values 14 16
[223]
THLE ABCC4
Mean 11.8
Standard deviation 2.1
Values 10 13
[224]
liver ABCC4
Mean 2.46
Standard deviation 0.72
Values 3 3.1 2.2 1.6
[225]
ref_hepatocyte NCOA2
Mean 1.14
Standard deviation 0.47
Values 1.2 0.91 0.47 1.5 1.7
[226]
HepG2 NCOA2
Mean 7.51
Standard deviation 4.4
Values 11 4.4
[227]
HepG2.C3A NCOA2
Mean 11.8
Standard deviation 4.3
Values 15 8.7
[228]
HuH.7 NCOA2
Mean 40.1
Standard deviation 18
Values 21 45 55
[229]
SNU475 NCOA2
Mean 19.2
Standard deviation 3.8
Values 17 22
[230]
THLE NCOA2
Mean 6.6
Standard deviation 1.4
Values 5.6 7.6
[231]
liver NCOA2
Mean 39.3
Standard deviation 20
Values 57 56 25 20