WP_PPAR_SIGNALING_PATHWAY |
Return to index |
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Order |
Gene |
Description |
ref_hepatocyte |
HepG2 |
HepG2.C3A |
HuH.7 |
SNU475 |
THLE |
liver |
1 |
APOA2 |
Apolipoprotein A-II |
[1] |
-0.21[2] |
-0.36[3] |
-0.98[4] |
-7.73[5] |
-7.42[6] |
-1.01[7] |
2 |
APOA1 |
Apolipoprotein A-I |
[8] |
-0.19[9] |
-0.11[10] |
-2.34[11] |
-8.24[12] |
-8.32[13] |
-0.04[14] |
3 |
APOC3 |
Apolipoprotein C-III |
[15] |
-4.06[16] |
-2.58[17] |
-3.78[18] |
-10.86[19] |
-11.40[20] |
-0.53[21] |
4 |
FABP1 |
Fatty acid-binding protein, liver |
[22] |
-5.59[23] |
-0.63[24] |
-0.05[25] |
-7.58[26] |
-7.45[27] |
-1.13[28] |
5 |
DBI |
Acyl-CoA-binding protein |
[29] |
-1.04[30] |
-0.32[31] |
-0.47[32] |
0.32[33] |
0.14[34] |
-2.29[35] |
6 |
SCP2 |
Non-specific lipid-transfer protein |
[36] |
0.21[37] |
0.14[38] |
0.80[39] |
2.39[40] |
2.31[41] |
1.45[42] |
7 |
HMGCS2 |
Hydroxymethylglutaryl-CoA synthase, mitochondrial |
[43] |
-9.39[44] |
-8.24[45] |
-0.92[46] |
-4.77[47] |
-9.11[48] |
1.94[49] |
8 |
SCD |
Acyl-CoA desaturase |
[50] |
3.42[51] |
4.05[52] |
5.22[53] |
2.84[54] |
2.00[55] |
1.61[56] |
9 |
ACSL1 |
Long-chain-fatty-acid--CoA ligase 1 |
[57] |
2.02[58] |
-1.64[59] |
-0.62[60] |
0.87[61] |
4.11[62] |
3.37[63] |
10 |
PCK1 |
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] |
[64] |
-5.00[65] |
-1.95[66] |
-9.23[67] |
[68] |
-10.85[69] |
2.17[70] |
11 |
CYP27A1 |
Sterol 26-hydroxylase, mitochondrial |
[71] |
1.96[72] |
1.55[73] |
-1.13[74] |
1.26[75] |
-0.22[76] |
1.20[77] |
12 |
PCK2 |
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial |
[78] |
3.47[79] |
0.87[80] |
1.95[81] |
0.43[82] |
2.54[83] |
0.83[84] |
13 |
ACAA1 |
3-ketoacyl-CoA thiolase, peroxisomal |
[85] |
1.59[86] |
1.88[87] |
0.41[88] |
1.48[89] |
1.86[90] |
1.25[91] |
14 |
CYP4A11 |
Cytochrome P450 4A11 |
[92] |
-10.62[93] |
-9.19[94] |
-10.66[95] |
-6.51[96] |
-7.45[97] |
1.99[98] |
15 |
SLC27A5 |
Bile acyl-CoA synthetase |
[99] |
-1.40[100] |
-1.35[101] |
-2.55[102] |
-1.67[103] |
-4.09[104] |
1.74[105] |
16 |
SLC27A2 |
Very long-chain acyl-CoA synthetase |
[106] |
0.51[107] |
-0.53[108] |
-0.39[109] |
1.75[110] |
-2.10[111] |
2.27[112] |
17 |
APOA5 |
Apolipoprotein A-V |
[113] |
1.40[114] |
1.91[115] |
0.16[116] |
-6.44[117] |
-5.08[118] |
3.29[119] |
18 |
ACADM |
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial |
[120] |
2.07[121] |
2.31[122] |
1.98[123] |
4.44[124] |
3.60[125] |
1.94[126] |
19 |
ILK |
Integrin-linked protein kinase |
[127] |
3.24[128] |
1.99[129] |
2.31[130] |
5.37[131] |
4.55[132] |
-0.34[133] |
20 |
CYP8B1 |
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase |
[134] |
-4.17[135] |
-2.83[136] |
-6.36[137] |
-4.16[138] |
-5.92[139] |
3.56[140] |
21 |
EHHADH |
Peroxisomal bifunctional enzyme |
[141] |
1.17[142] |
0.74[143] |
1.73[144] |
2.59[145] |
1.97[146] |
2.75[147] |
22 |
ACSL5 |
Long-chain-fatty-acid--CoA ligase 5 |
[148] |
4.29[149] |
3.01[150] |
-0.02[151] |
2.41[152] |
-0.06[153] |
2.21[154] |
23 |
ANGPTL4 |
Angiopoietin-related protein 4 |
[155] |
2.33[156] |
0.17[157] |
1.03[158] |
2.86[159] |
6.90[160] |
1.59[161] |
24 |
FADS2 |
Fatty acid desaturase 2 |
[162] |
2.54[163] |
2.80[164] |
5.44[165] |
6.15[166] |
3.74[167] |
0.71[168] |
25 |
ACOX2 |
Peroxisomal acyl-coenzyme A oxidase 2 |
[169] |
1.63[170] |
1.75[171] |
1.90[172] |
-2.05[173] |
0.34[174] |
2.23[175] |
26 |
ACSL3 |
Long-chain-fatty-acid--CoA ligase 3 |
[176] |
4.15[177] |
5.09[178] |
4.67[179] |
6.03[180] |
5.60[181] |
1.83[182] |
27 |
NR1H3 |
Oxysterols receptor LXR-alpha |
[183] |
2.38[184] |
2.20[185] |
3.53[186] |
3.08[187] |
1.81[188] |
0.80[189] |
28 |
RXRA |
Retinoic acid receptor RXR-alpha |
[190] |
3.99[191] |
2.59[192] |
3.84[193] |
5.83[194] |
5.58[195] |
3.26[196] |
29 |
FABP5 |
Fatty acid-binding protein, epidermal |
[197] |
4.28[198] |
2.51[199] |
3.70[200] |
3.65[201] |
4.19[202] |
-3.30[203] |
30 |
CPT2 |
Carnitine O-palmitoyltransferase 2, mitochondrial |
[204] |
2.54[205] |
2.20[206] |
3.19[207] |
4.37[208] |
4.71[209] |
3.01[210] |
31 |
ACOX1 |
Peroxisomal acyl-coenzyme A oxidase 1 |
[211] |
4.97[212] |
4.21[213] |
4.11[214] |
5.39[215] |
5.12[216] |
4.19[217] |
32 |
CPT1A |
Carnitine O-palmitoyltransferase 1, liver isoform |
[218] |
5.50[219] |
2.74[220] |
3.91[221] |
8.05[222] |
6.83[223] |
4.04[224] |
33 |
MMP1 |
Interstitial collagenase |
[225] |
-1.12[226] |
-6.09[227] |
[228] |
4.07[229] |
3.69[230] |
-11.02[231] |
34 |
PPARD |
Peroxisome proliferator-activated receptor delta |
[232] |
3.68[233] |
1.94[234] |
2.07[235] |
5.90[236] |
6.39[237] |
-0.51[238] |
35 |
ACSL4 |
Long-chain-fatty-acid--CoA ligase 4 |
[239] |
6.76[240] |
7.29[241] |
7.99[242] |
7.37[243] |
8.27[244] |
2.07[245] |
36 |
SLC27A4 |
Long-chain fatty acid transport protein 4 |
[246] |
4.02[247] |
2.98[248] |
2.03[249] |
5.04[250] |
5.88[251] |
1.55[252] |
37 |
ACOX3 |
Peroxisomal acyl-coenzyme A oxidase 3 |
[253] |
3.93[254] |
2.33[255] |
2.86[256] |
4.97[257] |
4.45[258] |
1.41[259] |
38 |
AQP7 |
Aquaporin-7 |
[260] |
-0.25[261] |
-0.33[262] |
-0.57[263] |
-2.86[264] |
-5.17[265] |
0.19[266] |
39 |
SORBS1 |
Sorbin and SH3 domain-containing protein 1 |
[267] |
3.04[268] |
4.71[269] |
5.82[270] |
2.07[271] |
2.57[272] |
4.06[273] |
40 |
RXRB |
Retinoic acid receptor RXR-beta |
[274] |
5.06[275] |
4.19[276] |
3.51[277] |
7.40[278] |
6.36[279] |
1.22[280] |
41 |
ACADL |
Long-chain specific acyl-CoA dehydrogenase, mitochondrial |
[281] |
-6.01[282] |
-7.84[283] |
-6.70[284] |
-4.26[285] |
-0.39[286] |
1.88[287] |
42 |
ME1 |
NADP-dependent malic enzyme |
[288] |
-2.30[289] |
-2.87[290] |
5.68[291] |
8.71[292] |
7.28[293] |
1.63[294] |
43 |
CYP7A1 |
Cholesterol 7-alpha-monooxygenase |
[295] |
-0.30[296] |
-3.83[297] |
-6.96[298] |
-4.15[299] |
[300] |
-1.84[301] |
44 |
PPARA |
Peroxisome proliferator-activated receptor alpha |
[302] |
4.72[303] |
4.50[304] |
5.75[305] |
5.85[306] |
5.10[307] |
5.26[308] |
45 |
PLTP |
Phospholipid transfer protein |
[309] |
5.55[310] |
4.19[311] |
5.98[312] |
2.40[313] |
7.26[314] |
2.74[315] |
46 |
PPARG |
Peroxisome proliferator-activated receptor gamma |
[316] |
3.96[317] |
4.37[318] |
5.29[319] |
6.66[320] |
6.71[321] |
0.73[322] |
47 |
PDPK1 |
3-phosphoinositide-dependent protein kinase 1 |
[323] |
6.38[324] |
6.37[325] |
5.48[326] |
7.25[327] |
7.73[328] |
3.61[329] |
48 |
PLIN1 |
Perilipin-1 |
[330] |
0.18[331] |
-0.63[332] |
-1.17[333] |
1.58[334] |
0.97[335] |
3.12[336] |
49 |
CD36 |
Platelet glycoprotein 4 |
[337] |
5.38[338] |
3.51[339] |
-1.18[340] |
9.00[341] |
0.07[342] |
4.20[343] |
50 |
SLC27A1 |
Long-chain fatty acid transport protein 1 |
[344] |
4.78[345] |
4.33[346] |
4.12[347] |
6.37[348] |
6.05[349] |
2.18[350] |
51 |
CPT1B |
Carnitine O-palmitoyltransferase 1, muscle isoform |
[351] |
0.32[352] |
0.86[353] |
1.67[354] |
1.45[355] |
1.90[356] |
-0.98[357] |
52 |
FABP3 |
Fatty acid-binding protein, heart |
[358] |
1.66[359] |
1.31[360] |
0.75[361] |
4.13[362] |
3.98[363] |
0.85[364] |
53 |
ACSL6 |
Long-chain-fatty-acid--CoA ligase 6 |
[365] |
3.98[366] |
5.15[367] |
2.94[368] |
4.55[369] |
4.06[370] |
4.13[371] |
54 |
LPL |
Lipoprotein lipase |
[372] |
[373] |
[374] |
-4.16[375] |
6.39[376] |
2.83[377] |
0.87[378] |
55 |
FABP2 |
Fatty acid-binding protein, intestinal |
[379] |
2.62[380] |
5.14[381] |
0.09[382] |
[383] |
0.95[384] |
-0.43[385] |
56 |
CPT1C |
Carnitine O-palmitoyltransferase 1, brain isoform |
[386] |
3.77[387] |
1.53[388] |
2.05[389] |
7.36[390] |
11.96[391] |
2.71[392] |
57 |
ADIPOQ |
Adiponectin |
[393] |
2.53[394] |
1.53[395] |
1.70[396] |
4.95[397] |
4.03[398] |
0.36[399] |
58 |
OLR1 |
Oxidized low-density lipoprotein receptor 1 |
[400] |
1.71[401] |
[402] |
3.46[403] |
12.59[404] |
9.31[405] |
0.04[406] |
59 |
FABP4 |
Fatty acid-binding protein, adipocyte |
[407] |
[408] |
[409] |
[410] |
[411] |
0.86[412] |
4.27[413] |
60 |
ACSBG1 |
Long-chain-fatty-acid--CoA ligase ACSBG1 |
[414] |
5.31[415] |
6.90[416] |
2.73[417] |
6.01[418] |
5.70[419] |
2.20[420] |
61 |
RXRG |
Retinoic acid receptor RXR-gamma |
[421] |
0.31[422] |
[423] |
[424] |
3.76[425] |
[426] |
3.62[427] |
62 |
ACSBG2 |
Long-chain-fatty-acid--CoA ligase ACSBG2 |
[428] |
4.49[429] |
4.21[430] |
5.52[431] |
6.98[432] |
7.61[433] |
3.20[434] |
63 |
SLC27A6 |
Long-chain fatty acid transport protein 6 |
[435] |
[436] |
[437] |
[438] |
4.12[439] |
7.17[440] |
-0.83[441] |
64 |
FABP7 |
Fatty acid-binding protein, brain |
[442] |
[443] |
[444] |
[445] |
[446] |
[447] |
[448] |
65 |
UCP1 |
Mitochondrial brown fat uncoupling protein 1 |
[449] |
[450] |
[451] |
[452] |
[453] |
[454] |
[455] |
66 |
FABP6 |
Gastrotropin |
[456] |
[457] |
[458] |
[459] |
[460] |
[461] |
[462] |
67 |
GK2 |
Glycerol kinase 2 |
[463] |
[464] |
[465] |
[466] |
[467] |
[468] |
[469] |
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