WP_PLURIPOTENT_STEM_CELL_DIFFERENTIATION_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | TF | Serotransferrin | [1] | -0.29[2] | -0.07[3] | -0.13[4] | -7.07[5] | -7.42[6] | -0.07[7] |
2 | IGF1 | Insulin-like growth factor I | [8] | -7.43[9] | -9.44[10] | -6.43[11] | 1.93[12] | -6.28[13] | 0.98[14] |
3 | VEGFA | Vascular endothelial growth factor A | [15] | 2.21[16] | 2.47[17] | 2.30[18] | 3.91[19] | 4.24[20] | 0.84[21] |
4 | IL6R | Interleukin-6 receptor subunit alpha | [22] | 0.78[23] | 0.03[24] | 0.43[25] | 2.60[26] | -1.89[27] | 1.72[28] |
5 | NT5E | 5'-nucleotidase | [29] | -0.31[30] | 2.08[31] | 3.33[32] | 2.80[33] | 4.41[34] | 1.45[35] |
6 | CSF1 | Macrophage colony-stimulating factor 1 | [36] | 2.04[37] | -3.75[38] | 1.66[39] | 6.47[40] | 5.56[41] | 0.47[42] |
7 | EPO | Erythropoietin | [43] | -0.14[44] | 0.95[45] | -1.67[46] | -6.20[47] | -8.46[48] | 0.05[49] |
8 | FGF2 | Fibroblast growth factor 2 | [50] | -5.69[51] | -6.51[52] | -1.13[53] | 4.41[54] | 5.60[55] | -1.60[56] |
9 | FST | Follistatin | [57] | 0.96[58] | 1.54[59] | -0.94[60] | -1.28[61] | -0.39[62] | 0.10[63] |
10 | TGFB1 | Transforming growth factor beta-1 | [64] | 4.47[65] | 2.35[66] | 0.83[67] | 7.31[68] | 6.15[69] | -1.17[70] |
11 | TNFSF11 | Tumor necrosis factor ligand superfamily member 11 | [71] | [72] | [73] | [74] | -7.06[75] | -1.97[76] | -3.70[77] |
12 | DKK1 | Dickkopf-related protein 1 | [78] | 6.27[79] | 1.55[80] | 3.23[81] | 4.81[82] | 7.18[83] | -5.38[84] |
13 | BMP4 | Bone morphogenetic protein 4 | [85] | 5.48[86] | 3.63[87] | 1.79[88] | 5.48[89] | 2.95[90] | -1.12[91] |
14 | FLT3LG | Fms-related tyrosine kinase 3 ligand | [92] | -1.26[93] | -2.24[94] | -0.55[95] | 1.14[96] | 1.84[97] | -2.10[98] |
15 | PDGFA | Platelet-derived growth factor subunit A | [99] | -0.01[100] | -0.87[101] | 2.44[102] | 3.13[103] | 1.83[104] | -0.69[105] |
16 | CSF1R | Macrophage colony-stimulating factor 1 receptor | [106] | -5.31[107] | -9.31[108] | -6.73[109] | 3.23[110] | -1.78[111] | 2.75[112] |
17 | TGFB3 | Transforming growth factor beta-3 | [113] | -0.55[114] | -2.50[115] | -1.51[116] | 3.64[117] | 2.19[118] | 0.52[119] |
18 | IL6 | Interleukin-6 | [120] | -7.45[121] | [122] | -3.69[123] | 2.62[124] | 4.75[125] | [126] |
19 | INHBA | Inhibin beta A chain | [127] | -6.50[128] | -7.29[129] | -5.61[130] | 6.40[131] | 2.40[132] | 0.67[133] |
20 | SHH | Sonic hedgehog protein | [134] | 1.38[135] | 0.15[136] | 1.46[137] | -3.71[138] | -4.24[139] | 0.19[140] |
21 | PDGFB | Platelet-derived growth factor subunit B | [141] | 4.05[142] | 2.84[143] | 1.25[144] | 3.54[145] | 2.72[146] | 0.43[147] |
22 | NOTCH1 | Neurogenic locus notch homolog protein 1 | [148] | 2.90[149] | 0.66[150] | 3.23[151] | 6.06[152] | 6.02[153] | 4.70[154] |
23 | WNT5A | Protein Wnt-5a | [155] | -2.20[156] | -3.26[157] | -0.87[158] | 10.07[159] | 11.25[160] | 1.38[161] |
24 | LEFTY1 | Left-right determination factor 1 | [162] | 0.45[163] | -2.10[164] | 0.36[165] | -1.09[166] | -1.42[167] | -0.87[168] |
25 | WNT7B | Protein Wnt-7b | [169] | 3.68[170] | 0.79[171] | 1.77[172] | 3.80[173] | 2.47[174] | -0.76[175] |
26 | FGF1 | Fibroblast growth factor 1 | [176] | -1.77[177] | -2.06[178] | -5.29[179] | 4.06[180] | 5.25[181] | 0.10[182] |
27 | IL11 | Interleukin-11 | [183] | 7.48[184] | 2.77[185] | 1.49[186] | 6.65[187] | 6.19[188] | -1.58[189] |
28 | KITLG | Kit ligand | [190] | 6.44[191] | 1.58[192] | 8.54[193] | 10.20[194] | 8.01[195] | 3.10[196] |
29 | KIT | Mast/stem cell growth factor receptor Kit | [197] | -1.99[198] | -4.95[199] | [200] | 5.97[201] | 0.06[202] | 3.70[203] |
30 | WNT2B | Protein Wnt-2b | [204] | 0.36[205] | 0.07[206] | 1.28[207] | 6.07[208] | 5.00[209] | 0.99[210] |
31 | CNTF | Ciliary neurotrophic factor | [211] | [212] | -1.37[213] | -2.19[214] | 2.38[215] | -0.09[216] | 0.78[217] |
32 | HGF | Hepatocyte growth factor | [218] | [219] | [220] | -0.50[221] | 8.07[222] | 4.71[223] | 8.96[224] |
33 | FGF8 | Fibroblast growth factor 8 | [225] | -2.33[226] | -3.06[227] | 2.66[228] | 1.56[229] | [230] | 2.76[231] |
34 | WNT2 | Protein Wnt-2 | [232] | [233] | [234] | -0.86[235] | 4.41[236] | 0.09[237] | 6.28[238] |
35 | NODAL | Nodal homolog | [239] | 4.89[240] | 0.11[241] | 6.14[242] | 7.04[243] | 5.36[244] | 4.74[245] |
36 | EGF | Pro-epidermal growth factor | [246] | 2.96[247] | 3.67[248] | 8.52[249] | 12.50[250] | 9.53[251] | 1.64[252] |
37 | TPO | Thyroid peroxidase | [253] | [254] | [255] | [256] | [257] | [258] | [259] |
38 | WNT3A | Protein Wnt-3a | [260] | [261] | [262] | [263] | [264] | [265] | [266] |
39 | ALK | ALK tyrosine kinase receptor | [267] | [268] | [269] | [270] | [271] | [272] | [273] |
40 | CXCR1 | C-X-C chemokine receptor type 1 | [274] | [275] | [276] | [277] | [278] | [279] | [280] |
41 | WNT1 | Proto-oncogene Wnt-1 | [281] | [282] | [283] | [284] | [285] | [286] | [287] |
42 | FGF4 | Fibroblast growth factor 4 | [288] | [289] | [290] | [291] | [292] | [293] | [294] |
43 | IL3 | Interleukin-3 | [295] | [296] | [297] | [298] | [299] | [300] | [301] |
44 | NTF4 | Neurotrophin-4 | [302] | [303] | [304] | [305] | [306] | [307] | [308] |
45 | GDF5 | Growth/differentiation factor 5 | [309] | [310] | [311] | [312] | [313] | [314] | [315] |
46 | NOG | Noggin | [316] | [317] | [318] | [319] | [320] | [321] | [322] |
47 | INS | Insulin | [323] | [324] | [325] | [326] | [327] | [328] | [329] |
48 | FGF10 | Fibroblast growth factor 10 | [330] | [331] | [332] | [333] | [334] | [335] | [336] |