WP_PKCGAMMA_CALCIUM_SIGNALING_PATHWAY_IN_ATAXIA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GNA11 Guanine nucleotide-binding protein subunit alpha-11 [1] -1.54[2] -2.15[3] -2.61[4] -2.37[5] -1.34[6] -2.67[7]
2 HOMER3 Homer protein homolog 3 [8] 0.68[9] -0.04[10] -0.52[11] 0.11[12] 0.59[13] -3.96[14]
3 GRIA3 Glutamate receptor 3 [15] -9.32[16] -8.71[17] -0.82[18] -9.12[19] -3.35[20] -2.21[21]
4 GNAQ Guanine nucleotide-binding protein G(q) subunit alpha [22] -0.80[23] -0.55[24] -0.45[25] 0.40[26] 0.85[27] 0.02[28]
5 PDK1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 1.50[29] 1.68[30] 0.88[31] 1.43[32] -0.11[33] 0.65[34]
6 PLCB3 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [35] 1.13[36] 0.08[37] 0.14[38] 1.53[39] 1.40[40] -0.69[41]
7 ATP2B2 Plasma membrane calcium-transporting ATPase 2 [42] -0.95[43] -0.65[44] 2.27[45] -6.30[46] -5.78[47] 2.56[48]
8 PLCB1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [49] 1.92[50] 3.01[51] 2.03[52] -0.40[53] 0.31[54] 1.07[55]
9 PLCB2 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [56] -2.49[57] -7.81[58] -10.06[59] -3.12[60] -3.60[61] 0.82[62]
10 ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 [63] 2.27[64] 1.62[65] 2.36[66] 1.67[67] 2.76[68] 3.23[69]
11 GNA15 Guanine nucleotide-binding protein subunit alpha-15 [70] -4.25[71] -6.50[72] [73] -7.21[74] -3.43[75] -1.32[76]
12 GNA14 Guanine nucleotide-binding protein subunit alpha-14 [77] -6.93[78] -7.86[79] -7.12[80] -7.47[81] -4.15[82] 1.82[83]
13 CA8 Carbonic anhydrase-related protein [84] -6.92[85] -6.10[86] -0.51[87] -0.62[88] 4.01[89] -3.88[90]
14 PRKCG Protein kinase C gamma type [91] -1.69[92] -1.55[93] -4.34[94] -2.25[95] -2.11[96] [97]
15 GRIA4 Glutamate receptor 4 [98] [99] -2.00[100] -0.75[101] 0.33[102] 0.26[103] 0.24[104]
16 PLCB4 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 [105] -0.62[106] -1.31[107] -0.71[108] 8.45[109] 6.39[110] 2.38[111]
17 CACNA1A Voltage-dependent P/Q-type calcium channel subunit alpha-1A [112] -2.97[113] -2.16[114] 0.32[115] 3.75[116] 2.04[117] 2.87[118]
18 GRIA1 Glutamate receptor 1 [119] -3.20[120] [121] [122] -1.84[123] -1.17[124] -1.28[125]
19 RYR3 Ryanodine receptor 3 [126] 3.11[127] 3.61[128] 1.05[129] 4.90[130] 4.01[131] 5.34[132]
20 GRM1 Metabotropic glutamate receptor 1 [133] 1.38[134] [135] -1.40[136] 4.39[137] 2.35[138] 1.71[139]
21 TRPC3 Short transient receptor potential channel 3 [140] [141] [142] [143] [144] [145] [146]
22 GRIA2 Glutamate receptor 2 [147] [148] [149] [150] [151] [152] [153]
[1]
ref_hepatocyte GNA11
Mean 10
Standard deviation 6.7
Values 12 2.8 3.8 19 12
[2]
HepG2 GNA11
Mean 14
Standard deviation 0.12
Values 14 14
[3]
HepG2.C3A GNA11
Mean 11.8
Standard deviation 0.77
Values 12 11
[4]
HuH.7 GNA11
Mean 10.9
Standard deviation 2.1
Values 8.6 11 13
[5]
SNU475 GNA11
Mean 8.12
Standard deviation 0.83
Values 7.5 8.7
[6]
THLE GNA11
Mean 15.8
Standard deviation 3.1
Values 14 18
[7]
liver GNA11
Mean 5.97
Standard deviation 1.7
Values 7.3 7 6.1 3.6
[8]
ref_hepatocyte HOMER3
Mean 2.19
Standard deviation 1.8
Values 2.3 0.51 0.78 5 2.3
[9]
HepG2 HOMER3
Mean 14.2
Standard deviation 2.9
Values 12 16
[10]
HepG2.C3A HOMER3
Mean 11
Standard deviation 1.8
Values 9.8 12
[11]
HuH.7 HOMER3
Mean 10.1
Standard deviation 2.3
Values 13 8.4 9.3
[12]
SNU475 HOMER3
Mean 9.82
Standard deviation 1.4
Values 11 8.8
[13]
THLE HOMER3
Mean 13.2
Standard deviation 0.95
Values 12 14
[14]
liver HOMER3
Mean 0.533
Standard deviation 0.34
Values 0.81 0.49 0.071 0.77
[15]
ref_hepatocyte GRIA3
Mean 2.03
Standard deviation 1.2
Values 2.5 2.2 2.2 0 3.3
[16]
HepG2 GRIA3
Mean 0.0129
Standard deviation 0.018
Values 0.026 0
[17]
HepG2.C3A GRIA3
Mean 0.0253
Standard deviation 0.0055
Values 0.021 0.029
[18]
HuH.7 GRIA3
Mean 7.64
Standard deviation 0.25
Values 7.9 7.6 7.4
[19]
SNU475 GRIA3
Mean 0.0152
Standard deviation 0.022
Values 0.03 0
[20]
THLE GRIA3
Mean 0.796
Standard deviation 0.15
Values 0.91 0.69
[21]
liver GRIA3
Mean 1.67
Standard deviation 0.33
Values 1.9 2 1.2 1.6
[22]
ref_hepatocyte GNAQ
Mean 1.88
Standard deviation 1
Values 3.6 1.1 1.1 1.6 2
[23]
HepG2 GNAQ
Mean 4.36
Standard deviation 1.2
Values 5.2 3.5
[24]
HepG2.C3A GNAQ
Mean 6.67
Standard deviation 0.93
Values 7.3 6
[25]
HuH.7 GNAQ
Mean 9.12
Standard deviation 3.7
Values 4.8 11 11
[26]
SNU475 GNAQ
Mean 10.4
Standard deviation 1.4
Values 9.4 11
[27]
THLE GNAQ
Mean 13.5
Standard deviation 3.4
Values 11 16
[28]
liver GNAQ
Mean 7.23
Standard deviation 3.8
Values 9.6 11 5.1 3
[29]
ref_hepatocyte PDK1
Mean 1.82
Standard deviation 1.1
Values 0.89 2.1 1.1 3.7 1.3
[30]
HepG2 PDK1
Mean 20.7
Standard deviation 5.2
Values 24 17
[31]
HepG2.C3A PDK1
Mean 30.3
Standard deviation 3.9
Values 33 28
[32]
HuH.7 PDK1
Mean 22.3
Standard deviation 0.9
Values 21 22 23
[33]
SNU475 PDK1
Mean 20.4
Standard deviation 4.6
Values 17 24
[34]
THLE PDK1
Mean 6.71
Standard deviation 0.29
Values 6.5 6.9
[35]
liver PDK1
Mean 10.8
Standard deviation 3
Values 7.1 12 10 14
[36]
ref_hepatocyte PLCB3
Mean 1.72
Standard deviation 1
Values 1.6 0.87 0.84 3.3 2
[37]
HepG2 PLCB3
Mean 15.2
Standard deviation 2.5
Values 17 13
[38]
HepG2.C3A PLCB3
Mean 9.48
Standard deviation 0.28
Values 9.7 9.3
[39]
HuH.7 PLCB3
Mean 12.5
Standard deviation 4.9
Values 16 6.9 15
[40]
SNU475 PLCB3
Mean 20.7
Standard deviation 4.4
Values 18 24
[41]
THLE PLCB3
Mean 18.1
Standard deviation 1.4
Values 17 19
[42]
liver PLCB3
Mean 4.04
Standard deviation 2.9
Values 7.5 5.4 1.7 1.5
[43]
ref_hepatocyte ATP2B2
Mean 1.3
Standard deviation 1.8
Values 0.0054 3.2 3.3 0 0.026
[44]
HepG2 ATP2B2
Mean 2.72
Standard deviation 0.13
Values 2.6 2.8
[45]
HepG2.C3A ATP2B2
Mean 4.32
Standard deviation 1.2
Values 3.5 5.2
[46]
HuH.7 ATP2B2
Mean 41.6
Standard deviation 6.3
Values 36 41 48
[47]
SNU475 ATP2B2
Mean 0.0688
Standard deviation 0.032
Values 0.091 0.046
[48]
THLE ATP2B2
Mean 0.0949
Standard deviation 0.067
Values 0.14 0.048
[49]
liver ATP2B2
Mean 29.1
Standard deviation 13
Values 33 45 20 18
[50]
ref_hepatocyte PLCB1
Mean 0.993
Standard deviation 1.3
Values 0.37 0.52 0.15 3.2 0.71
[51]
HepG2 PLCB1
Mean 15.2
Standard deviation 2.6
Values 17 13
[52]
HepG2.C3A PLCB1
Mean 41.8
Standard deviation 4.5
Values 39 45
[53]
HuH.7 PLCB1
Mean 26.9
Standard deviation 8.9
Values 19 36 26
[54]
SNU475 PLCB1
Mean 3.13
Standard deviation 0.39
Values 2.9 3.4
[55]
THLE PLCB1
Mean 4.93
Standard deviation 0.69
Values 5.4 4.4
[56]
liver PLCB1
Mean 7.93
Standard deviation 2.5
Values 6 11 8.6 6
[57]
ref_hepatocyte PLCB2
Mean 0.44
Standard deviation 0.47
Values 0.42 1.2 0.57 0 0.049
[58]
HepG2 PLCB2
Mean 0.316
Standard deviation 0.31
Values 0.099 0.53
[59]
HepG2.C3A PLCB2
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[60]
HuH.7 PLCB2
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[61]
SNU475 PLCB2
Mean 0.211
Standard deviation 0.062
Values 0.17 0.26
[62]
THLE PLCB2
Mean 0.145
Standard deviation 0.029
Values 0.12 0.16
[63]
liver PLCB2
Mean 2.94
Standard deviation 1.6
Values 4.9 3.5 1.8 1.5
[64]
ref_hepatocyte ITPR1
Mean 0.398
Standard deviation 0.44
Values 0.1 0.25 0.2 1.2 0.25
[65]
HepG2 ITPR1
Mean 7.73
Standard deviation 1.3
Values 6.8 8.7
[66]
HepG2.C3A ITPR1
Mean 6.36
Standard deviation 0.83
Values 5.8 7
[67]
HuH.7 ITPR1
Mean 13.6
Standard deviation 3.5
Values 9.6 16 15
[68]
SNU475 ITPR1
Mean 5.27
Standard deviation 3.4
Values 7.7 2.8
[69]
THLE ITPR1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[70]
liver ITPR1
Mean 14.2
Standard deviation 12
Values 29 20 4.3 3.8
[71]
ref_hepatocyte GNA15
Mean 0.271
Standard deviation 0.31
Values 0.27 0.76 0.33 0 0
[72]
HepG2 GNA15
Mean 0.0573
Standard deviation 0.081
Values 0 0.11
[73]
HepG2.C3A GNA15
Mean 0.0156
Standard deviation 0.0083
Values 0.021 0.0097
[74]
HuH.7 GNA15
Mean 0
Standard deviation 0
Values 0 0 0
[75]
SNU475 GNA15
Mean 0.0076
Standard deviation 0.011
Values 0.015 0
[76]
THLE GNA15
Mean 0.101
Standard deviation 0.0083
Values 0.095 0.11
[77]
liver GNA15
Mean 0.411
Standard deviation 0.3
Values 0.71 0.6 0.047 0.28
[78]
ref_hepatocyte GNA14
Mean 0.216
Standard deviation 0.25
Values 0 0.61 0.28 0 0.19
[79]
HepG2 GNA14
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[80]
HepG2.C3A GNA14
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[81]
HuH.7 GNA14
Mean 0.0103
Standard deviation 0.013
Values 0 0.0064 0.025
[82]
SNU475 GNA14
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[83]
THLE GNA14
Mean 0.0485
Standard deviation 0.023
Values 0.065 0.032
[84]
liver GNA14
Mean 2.89
Standard deviation 0.64
Values 2.7 2.1 3.5 3.3
[85]
ref_hepatocyte CA8
Mean 0.0641
Standard deviation 0.14
Values 0.32 0 0 0 0
[86]
HepG2 CA8
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[87]
HepG2.C3A CA8
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[88]
HuH.7 CA8
Mean 0.299
Standard deviation 0.16
Values 0.4 0.12 0.38
[89]
SNU475 CA8
Mean 0.174
Standard deviation 0.062
Values 0.22 0.13
[90]
THLE CA8
Mean 4.13
Standard deviation 0.36
Values 4.4 3.9
[91]
liver CA8
Mean 0.0165
Standard deviation 0.033
Values 0.066 0 0 0
[92]
ref_hepatocyte PRKCG
Mean 0.031
Standard deviation 0.057
Values 0.13 0.024 0 0 0
[93]
HepG2 PRKCG
Mean 0.0387
Standard deviation 0.043
Values 0.0086 0.069
[94]
HepG2.C3A PRKCG
Mean 0.055
Standard deviation 0.032
Values 0.032 0.078
[95]
HuH.7 PRKCG
Mean 0.0101
Standard deviation 0.0024
Values 0.0094 0.013 0.0082
[96]
SNU475 PRKCG
Mean 0.0272
Standard deviation 0.019
Values 0.041 0.014
[97]
THLE PRKCG
Mean 0.0287
Standard deviation 0.018
Values 0.041 0.016
[98]
liver PRKCG
Mean 0
Standard deviation 0
Values 0 0 0 0
[99]
ref_hepatocyte GRIA4
Mean 0.0206
Standard deviation 0.042
Values 0.095 0.0081 0 0 0
[100]
HepG2 GRIA4
Mean 0
Standard deviation 0
Values 0 0
[101]
HepG2.C3A GRIA4
Mean 0.0268
Standard deviation 0.038
Values 0.054 0
[102]
HuH.7 GRIA4
Mean 0.0817
Standard deviation 0.039
Values 0.037 0.11 0.098
[103]
SNU475 GRIA4
Mean 0.108
Standard deviation 0.017
Values 0.096 0.12
[104]
THLE GRIA4
Mean 0.099
Standard deviation 0.048
Values 0.065 0.13
[105]
liver GRIA4
Mean 0.0924
Standard deviation 0.11
Values 0.2 0.17 0 0
[106]
ref_hepatocyte PLCB4
Mean 0.0125
Standard deviation 0.024
Values 0.054 0.0081 0 0 0
[107]
HepG2 PLCB4
Mean 0.0329
Standard deviation 0.014
Values 0.043 0.023
[108]
HepG2.C3A PLCB4
Mean 0.0263
Standard deviation 0.023
Values 0.043 0.0097
[109]
HuH.7 PLCB4
Mean 0.0507
Standard deviation 0.032
Values 0.019 0.051 0.082
[110]
SNU475 PLCB4
Mean 18.2
Standard deviation 5.5
Values 14 22
[111]
THLE PLCB4
Mean 4.19
Standard deviation 1.3
Values 5.1 3.2
[112]
liver PLCB4
Mean 0.246
Standard deviation 0.29
Values 0.69 0.1 0.094 0.1
[113]
ref_hepatocyte CACNA1A
Mean 0.00833
Standard deviation 0.012
Values 0 0.024 0.017 0 0
[114]
HepG2 CACNA1A
Mean 0.00429
Standard deviation 0.0061
Values 0.0086 0
[115]
HepG2.C3A CACNA1A
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[116]
HuH.7 CACNA1A
Mean 0.0688
Standard deviation 0.035
Values 0.1 0.071 0.033
[117]
SNU475 CACNA1A
Mean 0.467
Standard deviation 0.15
Values 0.36 0.58
[118]
THLE CACNA1A
Mean 0.137
Standard deviation 0.066
Values 0.18 0.09
[119]
liver CACNA1A
Mean 0.231
Standard deviation 0.021
Values 0.23 0.26 0.24 0.21
[120]
ref_hepatocyte GRIA1
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[121]
HepG2 GRIA1
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[122]
HepG2.C3A GRIA1
Mean 0
Standard deviation 0
Values 0 0
[123]
HuH.7 GRIA1
Mean 0
Standard deviation 0
Values 0 0 0
[124]
SNU475 GRIA1
Mean 0.0076
Standard deviation 0.011
Values 0.015 0
[125]
THLE GRIA1
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[126]
liver GRIA1
Mean 0.0102
Standard deviation 0.013
Values 0.026 0.014 0 0
[127]
ref_hepatocyte RYR3
Mean 0.00335
Standard deviation 0.0046
Values 0 0.0081 0.0086 0 0
[128]
HepG2 RYR3
Mean 0.117
Standard deviation 0.035
Values 0.14 0.092
[129]
HepG2.C3A RYR3
Mean 0.214
Standard deviation 0.014
Values 0.2 0.22
[130]
HuH.7 RYR3
Mean 0.0462
Standard deviation 0.026
Values 0.019 0.071 0.049
[131]
SNU475 RYR3
Mean 0.418
Standard deviation 0.018
Values 0.41 0.43
[132]
THLE RYR3
Mean 0.216
Standard deviation 0.012
Values 0.22 0.21
[133]
liver RYR3
Mean 0.516
Standard deviation 0.31
Values 0.93 0.6 0.28 0.26
[134]
ref_hepatocyte GRM1
Mean 0.00109
Standard deviation 0.0024
Values 0.0054 0 0 0 0
[135]
HepG2 GRM1
Mean 0.0115
Standard deviation 0.016
Values 0 0.023
[136]
HepG2.C3A GRM1
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 GRM1
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[138]
SNU475 GRM1
Mean 0.0949
Standard deviation 0.063
Values 0.051 0.14
[139]
THLE GRM1
Mean 0.0222
Standard deviation 0.0063
Values 0.018 0.027
[140]
liver GRM1
Mean 0.0135
Standard deviation 0.019
Values 0.04 0.014 0 0
[141]
ref_hepatocyte TRPC3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 TRPC3
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A TRPC3
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 TRPC3
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[145]
SNU475 TRPC3
Mean 0.0948
Standard deviation 0.088
Values 0.16 0.032
[146]
THLE TRPC3
Mean 0.612
Standard deviation 0.03
Values 0.63 0.59
[147]
liver TRPC3
Mean 0.107
Standard deviation 0.081
Values 0.079 0.23 0.071 0.051
[148]
ref_hepatocyte GRIA2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 GRIA2
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A GRIA2
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 GRIA2
Mean 0.427
Standard deviation 0.1
Values 0.37 0.55 0.36
[152]
SNU475 GRIA2
Mean 0.142
Standard deviation 0.036
Values 0.12 0.17
[153]
THLE GRIA2
Mean 0
Standard deviation 0
Values 0 0
[154]
liver GRIA2
Mean 0.00688
Standard deviation 0.008
Values 0.013 0.014 0 0