WP_PHYSIOLOGICAL_AND_PATHOLOGICAL_HYPERTROPHY_OF_THE_HEART Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 AGT Angiotensinogen [1] -0.79[2] -0.21[3] -1.25[4] -5.45[5] -10.66[6] 0.86[7]
2 CALM2 Calmodulin-2 [8] -0.47[9] 0.02[10] -0.91[11] -0.59[12] -0.44[13] -2.71[14]
3 RHOA Transforming protein RhoA [15] 0.10[16] -0.77[17] -0.01[18] -0.07[19] 0.24[20] -2.31[21]
4 RAC1 Ras-related C3 botulinum toxin substrate 1 [22] 0.64[23] -0.06[24] 1.20[25] 1.17[26] 1.01[27] -1.96[28]
5 JUN Transcription factor AP-1 [29] 0.55[30] -1.37[31] -0.55[32] -0.55[33] -0.12[34] -2.80[35]
6 FOS Proto-oncogene c-Fos [36] -4.98[37] -4.09[38] -4.20[39] -5.01[40] -4.09[41] -2.29[42]
7 MAP2K3 Dual specificity mitogen-activated protein kinase kinase 3 [43] -0.18[44] -0.26[45] -0.81[46] -0.67[47] -0.95[48] -2.43[49]
8 STAT3 Signal transducer and activator of transcription 3 [50] 1.59[51] -0.28[52] 1.00[53] 1.40[54] 0.53[55] 1.42[56]
9 CALM1 Calmodulin-1 [57] 1.11[58] 0.78[59] 1.78[60] 2.74[61] 1.87[62] 0.63[63]
10 IL6ST Interleukin-6 receptor subunit beta [64] 1.30[65] 2.17[66] 2.24[67] 2.88[68] 3.91[69] 2.79[70]
11 MAPK1 Mitogen-activated protein kinase 1 [71] 2.75[72] 2.51[73] 2.89[74] 3.01[75] 2.51[76] 0.79[77]
12 MAPK14 Mitogen-activated protein kinase 14 [78] 2.51[79] 2.21[80] 2.33[81] 2.84[82] 2.17[83] 0.29[84]
13 MAPK8 Mitogen-activated protein kinase 8 [85] -0.41[86] 0.63[87] 0.05[88] 0.25[89] -0.03[90] -1.50[91]
14 CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta [92] 1.17[93] 1.10[94] 3.17[95] 1.83[96] 0.88[97] 0.42[98]
15 PPP3CB Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform 1.52[99] 1.94[100] 2.00[101] 1.91[102] 1.52[103] -1.14[104]
16 GATA4 Transcription factor GATA-4 [105] 1.82[106] 1.39[107] 3.36[108] -0.06[109] 2.73[110] -0.40[111]
17 EDN1 Endothelin-1 [112] 0.26[113] -3.66[114] 1.03[115] 0.68[116] -2.96[117] -3.03[118]
18 PPP3CA Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 1.76[119] 1.15[120] 1.50[121] 3.10[122] 2.70[123] 0.82[124]
19 MYEF2 Myelin expression factor 2 [125] 1.98[126] -2.06[127] -0.45[128] 3.62[129] 3.10[130] -3.32[131]
20 LIFR Leukemia inhibitory factor receptor [132] 1.96[133] 4.28[134] 5.40[135] 5.23[136] 4.57[137] 5.53[138]
21 PRKCE Protein kinase C epsilon type [139] 1.68[140] -0.21[141] 2.83[142] 2.14[143] 2.36[144] 2.57[145]
22 MAPK11 Mitogen-activated protein kinase 11 [146] 0.86[147] 0.39[148] 0.05[149] 1.51[150] 3.36[151] -0.83[152]
23 PRKCB Protein kinase C beta type [153] -5.78[154] -4.95[155] [156] 3.64[157] -1.81[158] 2.55[159]
24 CTF1 Cardiotrophin-1 [160] 2.73[161] 2.07[162] 0.05[163] -2.68[164] 2.21[165] -3.36[166]
25 NFATC4 Nuclear factor of activated T-cells, cytoplasmic 4 [167] 3.70[168] 0.59[169] 4.13[170] 3.90[171] 9.59[172] 4.23[173]
[1]
ref_hepatocyte AGT
Mean 439
Standard deviation 4.5e+02
Values 77 7e+02 1.1e+03 3.3e+02 6.7
[2]
HepG2 AGT
Mean 273
Standard deviation 17
Values 2.9e+02 2.6e+02
[3]
HepG2.C3A AGT
Mean 471
Standard deviation 99
Values 4e+02 5.4e+02
[4]
HuH.7 AGT
Mean 150
Standard deviation 28
Values 1.4e+02 1.8e+02 1.3e+02
[5]
SNU475 AGT
Mean 8.25
Standard deviation 2.2
Values 9.8 6.7
[6]
THLE AGT
Mean 0.276
Standard deviation 0.11
Values 0.35 0.2
[7]
liver AGT
Mean 2.25e+03
Standard deviation 2.3e+03
Values 6.1e+02 6.9e+02 5.5e+03 2.2e+03
[8]
ref_hepatocyte CALM2
Mean 339
Standard deviation 3.5e+02
Values 1e+02 1.7e+02 1.5e+02 3.2e+02 9.5e+02
[9]
HepG2 CALM2
Mean 263
Standard deviation 67
Values 3.1e+02 2.2e+02
[10]
HepG2.C3A CALM2
Mean 427
Standard deviation 1.7e+02
Values 5.5e+02 3.1e+02
[11]
HuH.7 CALM2
Mean 147
Standard deviation 58
Values 2e+02 84 1.6e+02
[12]
SNU475 CALM2
Mean 185
Standard deviation 12
Values 1.8e+02 1.9e+02
[13]
THLE CALM2
Mean 254
Standard deviation 11
Values 2.5e+02 2.6e+02
[14]
liver CALM2
Mean 146
Standard deviation 1.1e+02
Values 46 64 2.5e+02 2.3e+02
[15]
ref_hepatocyte RHOA
Mean 177
Standard deviation 1.2e+02
Values 1.4e+02 79 75 2.2e+02 3.8e+02
[16]
HepG2 RHOA
Mean 204
Standard deviation 38
Values 1.8e+02 2.3e+02
[17]
HepG2.C3A RHOA
Mean 129
Standard deviation 1.6
Values 1.3e+02 1.3e+02
[18]
HuH.7 RHOA
Mean 144
Standard deviation 23
Values 1.6e+02 1.2e+02 1.6e+02
[19]
SNU475 RHOA
Mean 139
Standard deviation 21
Values 1.2e+02 1.5e+02
[20]
THLE RHOA
Mean 214
Standard deviation 38
Values 1.9e+02 2.4e+02
[21]
liver RHOA
Mean 101
Standard deviation 59
Values 46 54 1.6e+02 1.4e+02
[22]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 81 47 45 28 59
[23]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 86 89
[24]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 57 67
[25]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[26]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 1e+02 89
[27]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[28]
liver RAC1
Mean 37.8
Standard deviation 32
Values 9.5 12 63 67
[29]
ref_hepatocyte JUN
Mean 42.9
Standard deviation 25
Values 66 20 73 26 30
[30]
HepG2 JUN
Mean 67.5
Standard deviation 36
Values 42 93
[31]
HepG2.C3A JUN
Mean 20.6
Standard deviation 11
Values 13 28
[32]
HuH.7 JUN
Mean 23.9
Standard deviation 19
Values 14 46 11
[33]
SNU475 JUN
Mean 24.2
Standard deviation 4.1
Values 27 21
[34]
THLE JUN
Mean 40.2
Standard deviation 4.7
Values 37 44
[35]
liver JUN
Mean 17.4
Standard deviation 8.4
Values 12 24 25 8.4
[36]
ref_hepatocyte FOS
Mean 40
Standard deviation 67
Values 9 27 1.6e+02 4 0.65
[37]
HepG2 FOS
Mean 1.37
Standard deviation 1
Values 0.66 2.1
[38]
HepG2.C3A FOS
Mean 2.92
Standard deviation 1.9
Values 1.6 4.3
[39]
HuH.7 FOS
Mean 1.77
Standard deviation 0.38
Values 2.2 1.6 1.5
[40]
SNU475 FOS
Mean 1.02
Standard deviation 0.13
Values 1.1 0.93
[41]
THLE FOS
Mean 2.4
Standard deviation 0.3
Values 2.2 2.6
[42]
liver FOS
Mean 23
Standard deviation 32
Values 5.7 4.8 71 10
[43]
ref_hepatocyte MAP2K3
Mean 32.7
Standard deviation 39
Values 1e+02 17 16 11 17
[44]
HepG2 MAP2K3
Mean 31
Standard deviation 5.7
Values 35 27
[45]
HepG2.C3A MAP2K3
Mean 34
Standard deviation 1.9
Values 33 35
[46]
HuH.7 MAP2K3
Mean 15.2
Standard deviation 4.8
Values 18 9.6 18
[47]
SNU475 MAP2K3
Mean 16.9
Standard deviation 1.1
Values 18 16
[48]
THLE MAP2K3
Mean 17.3
Standard deviation 3
Values 15 19
[49]
liver MAP2K3
Mean 17.2
Standard deviation 13
Values 7.1 4.9 30 26
[50]
ref_hepatocyte STAT3
Mean 30.1
Standard deviation 11
Values 18 36 46 26 25
[51]
HepG2 STAT3
Mean 97.5
Standard deviation 10
Values 1e+02 90
[52]
HepG2.C3A STAT3
Mean 30.7
Standard deviation 5.2
Values 27 34
[53]
HuH.7 STAT3
Mean 49.1
Standard deviation 15
Values 35 65 47
[54]
SNU475 STAT3
Mean 65.4
Standard deviation 12
Values 57 74
[55]
THLE STAT3
Mean 44.3
Standard deviation 6
Values 40 49
[56]
liver STAT3
Mean 227
Standard deviation 42
Values 2e+02 2.3e+02 1.9e+02 2.8e+02
[57]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 21 40 28 17 40
[58]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 71 65
[59]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 73 51
[60]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 92 64 90
[61]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.4e+02 1.8e+02
[62]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[63]
liver CALM1
Mean 127
Standard deviation 70
Values 57 80 2.1e+02 1.7e+02
[64]
ref_hepatocyte IL6ST
Mean 16.5
Standard deviation 5.8
Values 9.5 19 12 24 18
[65]
HepG2 IL6ST
Mean 43.6
Standard deviation 25
Values 61 26
[66]
HepG2.C3A IL6ST
Mean 92.3
Standard deviation 8.3
Values 98 86
[67]
HuH.7 IL6ST
Mean 63.5
Standard deviation 38
Values 35 1.1e+02 50
[68]
SNU475 IL6ST
Mean 100
Standard deviation 15
Values 1.1e+02 90
[69]
THLE IL6ST
Mean 252
Standard deviation 68
Values 3e+02 2e+02
[70]
liver IL6ST
Mean 321
Standard deviation 1.1e+02
Values 4.1e+02 4.2e+02 2.5e+02 2.1e+02
[71]
ref_hepatocyte MAPK1
Mean 10.7
Standard deviation 3.7
Values 13 7.4 6.1 14 13
[72]
HepG2 MAPK1
Mean 77.6
Standard deviation 22
Values 93 62
[73]
HepG2.C3A MAPK1
Mean 76.1
Standard deviation 7.2
Values 81 71
[74]
HuH.7 MAPK1
Mean 64.8
Standard deviation 7.4
Values 61 60 73
[75]
SNU475 MAPK1
Mean 71.1
Standard deviation 8
Values 65 77
[76]
THLE MAPK1
Mean 62.4
Standard deviation 14
Values 53 72
[77]
liver MAPK1
Mean 52.3
Standard deviation 14
Values 61 68 39 41
[78]
ref_hepatocyte MAPK14
Mean 8.71
Standard deviation 2
Values 7.2 8.3 7.5 12 8.5
[79]
HepG2 MAPK14
Mean 53.4
Standard deviation 8.7
Values 60 47
[80]
HepG2.C3A MAPK14
Mean 49.9
Standard deviation 0.11
Values 50 50
[81]
HuH.7 MAPK14
Mean 35.7
Standard deviation 1.3
Values 34 36 37
[82]
SNU475 MAPK14
Mean 51.3
Standard deviation 0.4
Values 51 52
[83]
THLE MAPK14
Mean 40
Standard deviation 3.6
Values 37 43
[84]
liver MAPK14
Mean 30.1
Standard deviation 8.3
Values 37 38 24 22
[85]
ref_hepatocyte MAPK8
Mean 7.1
Standard deviation 4.4
Values 15 4.7 3.8 6.5 5.6
[86]
HepG2 MAPK8
Mean 5.76
Standard deviation 1
Values 6.5 5.1
[87]
HepG2.C3A MAPK8
Mean 13.6
Standard deviation 4
Values 17 11
[88]
HuH.7 MAPK8
Mean 5.99
Standard deviation 0.68
Values 5.2 6.2 6.5
[89]
SNU475 MAPK8
Mean 6.98
Standard deviation 0.5
Values 6.6 7.3
[90]
THLE MAPK8
Mean 7.08
Standard deviation 1
Values 6.4 7.8
[91]
liver MAPK8
Mean 7.08
Standard deviation 1
Values 7.6 7.8 7.3 5.6
[92]
ref_hepatocyte CAMK2D
Mean 6.27
Standard deviation 4.6
Values 1.6 4.7 2.7 12 11
[93]
HepG2 CAMK2D
Mean 15.2
Standard deviation 5.9
Values 19 11
[94]
HepG2.C3A CAMK2D
Mean 16.7
Standard deviation 1.9
Values 18 15
[95]
HuH.7 CAMK2D
Mean 46.1
Standard deviation 5.5
Values 40 47 51
[96]
SNU475 CAMK2D
Mean 18.4
Standard deviation 4.5
Values 15 22
[97]
THLE CAMK2D
Mean 11.8
Standard deviation 1.2
Values 13 11
[98]
liver CAMK2D
Mean 23.7
Standard deviation 6.1
Values 19 21 33 22
[99]
ref_hepatocyte PPP3CB
Mean 4.68
Standard deviation 1.4
Values 3.1 4 4 6.3 5.9
[100]
HepG2 PPP3CB
Mean 14.5
Standard deviation 0.038
Values 15 14
[101]
HepG2.C3A PPP3CB
Mean 22.3
Standard deviation 2.3
Values 21 24
[102]
HuH.7 PPP3CB
Mean 15.2
Standard deviation 1.8
Values 16 13 17
[103]
SNU475 PPP3CB
Mean 14.5
Standard deviation 3.6
Values 12 17
[104]
THLE PPP3CB
Mean 13.7
Standard deviation 2.2
Values 12 15
[105]
liver PPP3CB
Mean 5.99
Standard deviation 0.99
Values 6.7 7 5.4 4.9
[106]
ref_hepatocyte GATA4
Mean 3.97
Standard deviation 2.3
Values 2.3 4.3 6 6.3 1
[107]
HepG2 GATA4
Mean 15.1
Standard deviation 1.5
Values 16 14
[108]
HepG2.C3A GATA4
Mean 12.9
Standard deviation 0.72
Values 12 13
[109]
HuH.7 GATA4
Mean 33.3
Standard deviation 6.5
Values 29 41 30
[110]
SNU475 GATA4
Mean 3.13
Standard deviation 0.12
Values 3 3.2
[111]
THLE GATA4
Mean 26.9
Standard deviation 1.1
Values 26 28
[112]
liver GATA4
Mean 8.47
Standard deviation 2.5
Values 6.2 6.8 12 9.2
[113]
ref_hepatocyte EDN1
Mean 3.73
Standard deviation 6.6
Values 2.9 0.27 0.069 0.056 15
[114]
HepG2 EDN1
Mean 4.8
Standard deviation 1.5
Values 3.7 5.9
[115]
HepG2.C3A EDN1
Mean 0.366
Standard deviation 0.32
Values 0.14 0.59
[116]
HuH.7 EDN1
Mean 6.19
Standard deviation 0.93
Values 5.9 7.2 5.5
[117]
SNU475 EDN1
Mean 4.91
Standard deviation 2.4
Values 3.2 6.6
[118]
THLE EDN1
Mean 0.49
Standard deviation 0.24
Values 0.32 0.66
[119]
liver EDN1
Mean 1.29
Standard deviation 0.82
Values 0.44 1.2 1.2 2.4
[120]
ref_hepatocyte PPP3CA
Mean 3.28
Standard deviation 1.4
Values 2.6 3.4 2.1 2.6 5.6
[121]
HepG2 PPP3CA
Mean 12
Standard deviation 2.1
Values 13 11
[122]
HepG2.C3A PPP3CA
Mean 9.04
Standard deviation 0.97
Values 8.4 9.7
[123]
HuH.7 PPP3CA
Mean 7.59
Standard deviation 0.7
Values 7 7.5 8.3
[124]
SNU475 PPP3CA
Mean 23.2
Standard deviation 2.3
Values 25 22
[125]
THLE PPP3CA
Mean 21.8
Standard deviation 1.1
Values 21 23
[126]
liver PPP3CA
Mean 16.3
Standard deviation 7.4
Values 14 10 27 13
[127]
ref_hepatocyte MYEF2
Mean 0.996
Standard deviation 1.8
Values 0.26 0.11 0.06 4.3 0.28
[128]
HepG2 MYEF2
Mean 4.24
Standard deviation 0.85
Values 4.8 3.6
[129]
HepG2.C3A MYEF2
Mean 0.296
Standard deviation 0.0061
Values 0.3 0.29
[130]
HuH.7 MYEF2
Mean 0.594
Standard deviation 0.17
Values 0.46 0.79 0.53
[131]
SNU475 MYEF2
Mean 10.1
Standard deviation 3.1
Values 7.9 12
[132]
THLE MYEF2
Mean 8.68
Standard deviation 0.56
Values 9.1 8.3
[133]
liver MYEF2
Mean 0.281
Standard deviation 0.16
Values 0.34 0.49 0.14 0.15
[134]
ref_hepatocyte LIFR
Mean 0.724
Standard deviation 1
Values 0.18 0.41 0.2 2.6 0.25
[135]
HepG2 LIFR
Mean 3.03
Standard deviation 1.3
Values 3.9 2.1
[136]
HepG2.C3A LIFR
Mean 17.4
Standard deviation 0.87
Values 17 18
[137]
HuH.7 LIFR
Mean 24.9
Standard deviation 7.5
Values 17 31 27
[138]
SNU475 LIFR
Mean 22.3
Standard deviation 5.6
Values 26 18
[139]
THLE LIFR
Mean 17.5
Standard deviation 6.4
Values 22 13
[140]
liver LIFR
Mean 94.5
Standard deviation 28
Values 1.2e+02 1.1e+02 84 59
[141]
ref_hepatocyte PRKCE
Mean 0.713
Standard deviation 0.29
Values 0.38 1.1 0.94 0.58 0.57
[142]
HepG2 PRKCE
Mean 2.46
Standard deviation 0.34
Values 2.2 2.7
[143]
HepG2.C3A PRKCE
Mean 0.767
Standard deviation 0.098
Values 0.7 0.84
[144]
HuH.7 PRKCE
Mean 4.14
Standard deviation 0.97
Values 3.2 5.1 4.1
[145]
SNU475 PRKCE
Mean 2.58
Standard deviation 0.11
Values 2.7 2.5
[146]
THLE PRKCE
Mean 3.72
Standard deviation 0.4
Values 3.4 4
[147]
liver PRKCE
Mean 12
Standard deviation 13
Values 31 7.3 5.6 3.9
[148]
ref_hepatocyte MAPK11
Mean 0.382
Standard deviation 0.29
Values 0.22 0.64 0.71 0 0.34
[149]
HepG2 MAPK11
Mean 0.749
Standard deviation 0.18
Values 0.88 0.62
[150]
HepG2.C3A MAPK11
Mean 0.621
Standard deviation 0.12
Values 0.71 0.53
[151]
HuH.7 MAPK11
Mean 0.322
Standard deviation 0.15
Values 0.49 0.2 0.28
[152]
SNU475 MAPK11
Mean 0.898
Standard deviation 0.33
Values 0.66 1.1
[153]
THLE MAPK11
Mean 4.01
Standard deviation 0.7
Values 4.5 3.5
[154]
liver MAPK11
Mean 0.609
Standard deviation 0.32
Values 0.75 0.49 0.96 0.23
[155]
ref_hepatocyte PRKCB
Mean 0.255
Standard deviation 0.29
Values 0.4 0.67 0.2 0 0
[156]
HepG2 PRKCB
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[157]
HepG2.C3A PRKCB
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[158]
HuH.7 PRKCB
Mean 0
Standard deviation 0
Values 0 0 0
[159]
SNU475 PRKCB
Mean 2.62
Standard deviation 2.8
Values 4.6 0.61
[160]
THLE PRKCB
Mean 0.0742
Standard deviation 0.037
Values 0.1 0.048
[161]
liver PRKCB
Mean 4.2
Standard deviation 2.1
Values 5 6.8 2.7 2.2
[162]
ref_hepatocyte CTF1
Mean 0.176
Standard deviation 0.17
Values 0.28 0.36 0.24 0 0
[163]
HepG2 CTF1
Mean 1.26
Standard deviation 0.65
Values 0.81 1.7
[164]
HepG2.C3A CTF1
Mean 0.921
Standard deviation 0.64
Values 0.47 1.4
[165]
HuH.7 CTF1
Mean 0.148
Standard deviation 0.0013
Values 0.15 0.15 0.15
[166]
SNU475 CTF1
Mean 0.0226
Standard deviation 0.025
Values 0.041 0.0046
[167]
THLE CTF1
Mean 0.832
Standard deviation 0.078
Values 0.89 0.78
[168]
liver CTF1
Mean 0.0486
Standard deviation 0.062
Values 0.013 0.014 0.14 0.026
[169]
ref_hepatocyte NFATC4
Mean 0.0185
Standard deviation 0.03
Values 0.068 0.024 0 0 0
[170]
HepG2 NFATC4
Mean 0.258
Standard deviation 0.27
Values 0.069 0.45
[171]
HepG2.C3A NFATC4
Mean 0.0345
Standard deviation 0.034
Values 0.011 0.058
[172]
HuH.7 NFATC4
Mean 0.263
Standard deviation 0.25
Values 0.12 0.55 0.11
[173]
SNU475 NFATC4
Mean 0.227
Standard deviation 0.02
Values 0.21 0.24
[174]
THLE NFATC4
Mean 14.5
Standard deviation 0.74
Values 15 14
[175]
liver NFATC4
Mean 0.981
Standard deviation 0.66
Values 1.9 0.7 0.89 0.41