WP_PHOTODYNAMIC_THERAPYINDUCED_HIF1_SURVIVAL_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | LDHA | L-lactate dehydrogenase A chain | [1] | -0.87[2] | -0.83[3] | -0.08[4] | -0.72[5] | -1.73[6] | 0.26[7] |
2 | SERPINE1 | Plasminogen activator inhibitor 1 | [8] | -0.05[9] | 0.26[10] | -5.87[11] | -4.52[12] | 1.76[13] | -3.87[14] |
3 | IGFBP2 | Insulin-like growth factor-binding protein 2 | [15] | -4.50[16] | -8.15[17] | -11.34[18] | -8.83[19] | -3.20[20] | -0.43[21] |
4 | PGK1 | Phosphoglycerate kinase 1 | [22] | 0.17[23] | -0.59[24] | -0.13[25] | 0.67[26] | -0.39[27] | -0.24[28] |
5 | IGFBP1 | Insulin-like growth factor-binding protein 1 | [29] | -1.34[30] | 1.82[31] | -5.37[32] | -10.50[33] | -10.39[34] | -0.53[35] |
6 | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 | [36] | -1.20[37] | 0.32[38] | 0.72[39] | -1.64[40] | -1.96[41] | 0.22[42] |
7 | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 | [43] | -1.33[44] | -1.30[45] | -0.50[46] | -0.56[47] | -0.47[48] | 0.09[49] |
8 | BCL2L1 | Bcl-2-like protein 1 | [50] | 0.96[51] | 0.43[52] | 2.00[53] | -1.33[54] | -1.34[55] | -0.81[56] |
9 | HIF1A | Hypoxia-inducible factor 1-alpha | [57] | -1.34[58] | -1.58[59] | -0.18[60] | 1.58[61] | 1.56[62] | -0.80[63] |
10 | PDHA1 | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | -1.96[64] | -1.89[65] | -0.26[66] | -1.26[67] | -2.11[68] | 0.16[69] | |
11 | BAX | Apoptosis regulator BAX | [70] | -0.85[71] | -1.56[72] | -1.42[73] | -2.32[74] | -2.33[75] | -3.95[76] |
12 | PFKL | ATP-dependent 6-phosphofructokinase, liver type | [77] | -0.09[78] | 0.05[79] | 0.51[80] | -0.14[81] | -0.97[82] | 0.72[83] |
13 | SLC16A1 | Monocarboxylate transporter 1 | [84] | -0.22[85] | 0.70[86] | 1.54[87] | -0.05[88] | 0.25[89] | 1.19[90] |
14 | VEGFA | Vascular endothelial growth factor A | [91] | 0.04[92] | 1.46[93] | 0.67[94] | -0.27[95] | 0.04[96] | 0.79[97] |
15 | BID | BH3-interacting domain death agonist | [98] | -1.45[99] | -1.26[100] | -1.03[101] | -1.00[102] | -1.94[103] | 0.18[104] |
16 | EGLN1 | Egl nine homolog 1 | [105] | 0.14[106] | -0.11[107] | -0.03[108] | 0.76[109] | 0.32[110] | 1.51[111] |
17 | SLC2A3 | Solute carrier family 2, facilitated glucose transporter member 3 | [112] | 3.44[113] | 0.58[114] | -5.34[115] | -2.45[116] | -0.68[117] | -1.28[118] |
18 | BIRC5 | Baculoviral IAP repeat-containing protein 5 | [119] | 0.39[120] | 0.93[121] | 1.49[122] | -0.03[123] | 0.40[124] | -2.30[125] |
19 | BAK1 | Bcl-2 homologous antagonist/killer | [126] | -0.29[127] | -0.66[128] | -0.09[129] | 0.48[130] | -0.44[131] | -1.78[132] |
20 | ARNT | Aryl hydrocarbon receptor nuclear translocator | [133] | -0.77[134] | -0.89[135] | 0.59[136] | 0.65[137] | 0.02[138] | 1.54[139] |
21 | BCL2A1 | Bcl-2-related protein A1 | [140] | -5.95[141] | -7.69[142] | -11.49[143] | -9.97[144] | -6.83[145] | -4.88[146] |
22 | TP53 | Cellular tumor antigen p53 | [147] | 0.45[148] | 0.11[149] | 1.47[150] | 0.58[151] | -0.16[152] | -0.03[153] |
23 | BNIP3L | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | [154] | 1.10[155] | 1.15[156] | 2.31[157] | 1.69[158] | 0.72[159] | 1.65[160] |
24 | EPO | Erythropoietin | [161] | -2.32[162] | -0.07[163] | -3.31[164] | -10.38[165] | -12.66[166] | 0.00[167] |
25 | HIF1AN | Hypoxia-inducible factor 1-alpha inhibitor | [168] | 1.24[169] | 1.32[170] | 2.48[171] | 0.92[172] | 0.62[173] | 1.23[174] |
26 | IGFBP3 | Insulin-like growth factor-binding protein 3 | [175] | 1.86[176] | -2.94[177] | -2.86[178] | -0.27[179] | -1.65[180] | 4.24[181] |
27 | EDN1 | Endothelin-1 | [182] | -1.96[183] | -5.42[184] | -0.67[185] | -1.19[186] | -5.08[187] | -2.03[188] |
28 | SLC2A1 | Solute carrier family 2, facilitated glucose transporter member 1 | [189] | 5.46[190] | 2.56[191] | 2.24[192] | 2.73[193] | 1.47[194] | -1.34[195] |
29 | PMAIP1 | Phorbol-12-myristate-13-acetate-induced protein 1 | [196] | -1.13[197] | -4.41[198] | -0.25[199] | 1.57[200] | 0.39[201] | -4.29[202] |
30 | TGFA | Protransforming growth factor alpha | [203] | 0.61[204] | 1.76[205] | -8.68[206] | -1.67[207] | -3.30[208] | -0.38[209] |
31 | HK1 | Hexokinase-1 | [210] | -0.27[211] | -5.07[212] | -5.74[213] | 3.82[214] | 3.47[215] | 0.92[216] |
32 | TGFB3 | Transforming growth factor beta-3 | [217] | -2.72[218] | -3.51[219] | -3.14[220] | -0.54[221] | -2.00[222] | 0.46[223] |
33 | NOS2 | Nitric oxide synthase, inducible | [224] | -1.16[225] | [226] | -6.71[227] | -5.57[228] | -6.86[229] | -7.30[230] |
34 | ANGPT2 | Angiopoietin-2 | [231] | -2.91[232] | -1.58[233] | -0.41[234] | -1.22[235] | -1.60[236] | 5.00[237] |
35 | PTGS2 | Prostaglandin G/H synthase 2 | [238] | [239] | -3.72[240] | -2.86[241] | 2.15[242] | 7.57[243] | 2.85[244] |
36 | ANGPT1 | Angiopoietin-1 | [245] | -0.89[246] | [247] | 6.74[248] | 9.70[249] | 4.86[250] | 6.69[251] |
37 | PKM | Pyruvate kinase PKM | [252] | [253] | [254] | [255] | [256] | [257] | [258] |