WP_PHOTODYNAMIC_THERAPYINDUCED_AP1_SURVIVAL_SIGNALING | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | HSP90AA1 | Heat shock protein HSP 90-alpha | [1] | -0.82[2] | 0.15[3] | -0.47[4] | 0.02[5] | -0.28[6] | -0.76[7] |
2 | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 | [8] | -0.32[9] | -0.38[10] | -0.04[11] | 0.09[12] | 0.59[13] | 0.58[14] |
3 | JUN | Transcription factor AP-1 | [15] | -0.67[16] | -2.21[17] | -1.79[18] | -1.77[19] | -1.19[20] | -1.31[21] |
4 | CDKN1A | Cyclin-dependent kinase inhibitor 1 | [22] | 0.66[23] | -0.73[24] | -3.26[25] | -2.05[26] | 0.52[27] | -1.34[28] |
5 | FOS | Proto-oncogene c-Fos | [29] | -6.19[30] | -4.93[31] | -5.44[32] | -6.23[33] | -5.15[34] | -0.81[35] |
6 | JUNB | Transcription factor jun-B | [36] | -2.13[37] | -3.00[38] | -2.13[39] | -2.23[40] | -1.38[41] | -0.89[42] |
7 | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 | [43] | -1.40[44] | -1.10[45] | -2.04[46] | -1.89[47] | -2.01[48] | -0.94[49] |
8 | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A | [50] | -0.65[51] | -1.11[52] | -0.66[53] | 0.30[54] | 0.50[55] | 0.57[56] |
9 | BCL2L1 | Bcl-2-like protein 1 | [57] | 1.96[58] | 1.35[59] | 2.46[60] | -0.68[61] | -0.28[62] | -0.32[63] |
10 | BAX | Apoptosis regulator BAX | [64] | 0.15[65] | -0.64[66] | -0.95[67] | -1.67[68] | -1.27[69] | -3.46[70] |
11 | CCND1 | G1/S-specific cyclin-D1 | [71] | 2.87[72] | 0.37[73] | 1.36[74] | 1.81[75] | 0.35[76] | 1.55[77] |
12 | TNFSF10 | Tumor necrosis factor ligand superfamily member 10 | [78] | -4.65[79] | -3.05[80] | -0.27[81] | -2.54[82] | -5.77[83] | -0.89[84] |
13 | BCL3 | B-cell lymphoma 3 protein | [85] | -1.61[86] | -2.82[87] | -1.38[88] | -1.38[89] | -1.43[90] | -1.45[91] |
14 | CFLAR | CASP8 and FADD-like apoptosis regulator | [92] | -0.56[93] | 0.18[94] | -0.11[95] | -0.61[96] | -0.43[97] | 2.06[98] |
15 | NFE2L2 | Nuclear factor erythroid 2-related factor 2 | [99] | 0.59[100] | 1.52[101] | 1.28[102] | 0.40[103] | 0.65[104] | 0.67[105] |
16 | BID | BH3-interacting domain death agonist | [106] | -0.45[107] | -0.34[108] | -0.57[109] | -0.35[110] | -0.88[111] | 0.67[112] |
17 | FAS | Tumor necrosis factor receptor superfamily member 6 | [113] | -1.78[114] | -1.00[115] | -8.85[116] | -1.81[117] | -1.28[118] | -1.23[119] |
18 | MAPK14 | Mitogen-activated protein kinase 14 | [120] | 1.30[121] | 1.37[122] | 1.10[123] | 1.62[124] | 1.11[125] | 1.78[126] |
19 | ATF2 | Cyclic AMP-dependent transcription factor ATF-2 | [127] | 0.46[128] | 1.51[129] | 1.89[130] | 0.72[131] | 0.50[132] | 1.52[133] |
20 | MAPK8 | Mitogen-activated protein kinase 8 | [134] | -1.62[135] | -0.21[136] | -1.19[137] | -0.97[138] | -1.10[139] | -0.02[140] |
21 | ELK1 | ETS domain-containing protein Elk-1 | [141] | -0.49[142] | -2.63[143] | -0.05[144] | 0.21[145] | 0.81[146] | 0.33[147] |
22 | BAK1 | Bcl-2 homologous antagonist/killer | [148] | 0.72[149] | 0.26[150] | 0.38[151] | 1.12[152] | 0.62[153] | -1.29[154] |
23 | EGFR | Epidermal growth factor receptor | [155] | -0.87[156] | -1.25[157] | 1.79[158] | 0.37[159] | 1.00[160] | 3.15[161] |
24 | MAPK13 | Mitogen-activated protein kinase 13 | [162] | 2.17[163] | 2.57[164] | 0.04[165] | -1.95[166] | -0.42[167] | -1.22[168] |
25 | TP53 | Cellular tumor antigen p53 | [169] | 1.46[170] | 1.02[171] | 1.94[172] | 1.23[173] | 0.90[174] | 0.45[175] |
26 | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 | [176] | 0.53[177] | 1.16[178] | 0.51[179] | 1.14[180] | 0.55[181] | 1.56[182] |
27 | TRAF2 | TNF receptor-associated factor 2 | [183] | 0.05[184] | 0.11[185] | 0.00[186] | 0.05[187] | 0.08[188] | -0.30[189] |
28 | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 | [190] | 0.79[191] | 0.93[192] | 1.66[193] | 0.22[194] | 0.79[195] | -0.26[196] |
29 | CCNE1 | G1/S-specific cyclin-E1 | [197] | 1.06[198] | 1.17[199] | -0.49[200] | -0.47[201] | 0.14[202] | -4.13[203] |
30 | CCNA2 | Cyclin-A2 | [204] | 2.03[205] | 3.04[206] | 2.54[207] | 1.94[208] | 3.34[209] | -0.73[210] |
31 | RB1 | Retinoblastoma-associated protein | [211] | 1.04[212] | 1.54[213] | 2.26[214] | 2.21[215] | 2.55[216] | 1.97[217] |
32 | BMF | Bcl-2-modifying factor | [218] | 0.64[219] | 1.01[220] | 2.23[221] | 3.57[222] | -1.77[223] | -0.30[224] |
33 | HBEGF | Proheparin-binding EGF-like growth factor | [225] | -1.16[226] | -1.98[227] | -2.89[228] | 0.24[229] | -0.06[230] | -1.94[231] |
34 | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 | [232] | 0.11[233] | -3.10[234] | 1.91[235] | 0.94[236] | -3.08[237] | -1.12[238] |
35 | BCL2L11 | Bcl-2-like protein 11 | [239] | 1.33[240] | 1.34[241] | 1.82[242] | 1.80[243] | 0.79[244] | 2.48[245] |
36 | IL6 | Interleukin-6 | [246] | -8.62[247] | [248] | -4.86[249] | -0.92[250] | 1.61[251] | [252] |
37 | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 | [253] | -4.48[254] | -7.40[255] | -1.36[256] | -1.93[257] | 2.48[258] | 3.55[259] |
38 | TRAF6 | TNF receptor-associated factor 6 | [260] | 0.91[261] | 0.80[262] | 1.52[263] | 1.59[264] | 1.07[265] | 3.40[266] |
39 | MAPK12 | Mitogen-activated protein kinase 12 | [267] | 2.64[268] | 2.30[269] | 3.57[270] | 1.42[271] | 2.68[272] | -0.41[273] |
40 | FGF7 | Fibroblast growth factor 7 | [274] | -9.47[275] | -5.77[276] | [277] | -5.44[278] | -1.16[279] | -0.95[280] |
41 | PDGFRA | Platelet-derived growth factor receptor alpha | [281] | -3.80[282] | -4.78[283] | 3.01[284] | 0.46[285] | 5.15[286] | 5.82[287] |
42 | MAPK11 | Mitogen-activated protein kinase 11 | [288] | -0.35[289] | -0.45[290] | -1.19[291] | 0.29[292] | 2.30[293] | 0.66[294] |
43 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | [295] | 3.91[296] | 1.67[297] | 5.23[298] | 5.14[299] | 6.94[300] | -1.66[301] |
44 | TRAF5 | TNF receptor-associated factor 5 | [302] | 0.52[303] | 0.72[304] | 1.26[305] | 5.44[306] | 3.22[307] | 2.37[308] |
45 | IFNG | Interferon gamma | [309] | [310] | [311] | [312] | -0.76[313] | [314] | -1.80[315] |
46 | MMP2 | 72 kDa type IV collagenase | [316] | 3.26[317] | -3.73[318] | -2.30[319] | 7.37[320] | 6.94[321] | 4.43[322] |
47 | TNF | Tumor necrosis factor | [323] | 0.92[324] | -1.21[325] | -5.66[326] | -2.29[327] | -5.50[328] | -1.40[329] |
48 | BCL2 | Apoptosis regulator Bcl-2 | [330] | -3.03[331] | 2.37[332] | -4.88[333] | 1.71[334] | 1.44[335] | 3.73[336] |
49 | FASLG | Tumor necrosis factor ligand superfamily member 6 | [337] | -3.99[338] | -2.12[339] | -5.94[340] | [341] | [342] | 1.08[343] |
50 | IL2 | Interleukin-2 | [344] | [345] | [346] | [347] | [348] | [349] | [350] |
51 | MIR8085 | [351] | [352] | [353] | [354] | [355] | [356] | [357] |