WP_PATHOGENESIS_OF_SARSCOV2_MEDIATED_BY_NSP9NSP10_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CRP C-reactive protein [1] [2] [3] -9.36[4] [5] -9.70[6] 0.01[7]
2 LBP Lipopolysaccharide-binding protein [8] -3.04[9] -5.59[10] 0.58[11] -4.86[12] -11.09[13] 0.05[14]
3 HLA-DRA HLA class II histocompatibility antigen, DR alpha chain [15] -4.65[16] [17] -6.59[18] 2.52[19] -0.45[20] -0.58[21]
4 HLA-DRB1 HLA class II histocompatibility antigen, DRB1-15 beta chain [22] 0.18[23] [24] [25] 2.17[26] -3.95[27] -1.67[28]
5 CD4 T-cell surface glycoprotein CD4 [29] 2.86[30] 5.52[31] 1.48[32] 0.82[33] -2.28[34] -0.10[35]
6 IGLL1 Immunoglobulin lambda-like polypeptide 1 [36] [37] [38] -4.12[39] [40] -5.53[41] -8.97[42]
7 HLA-DRB5 HLA class II histocompatibility antigen, DR beta 5 chain [43] -2.47[44] [45] [46] -0.09[47] [48] -5.86[49]
8 FYN Tyrosine-protein kinase Fyn [50] 9.56[51] 1.44[52] 8.59[53] 9.74[54] 10.23[55] 0.96[56]
9 NKRF NF-kappa-B-repressing factor [57] 8.85[58] 9.59[59] 9.43[60] 9.48[61] 8.22[62] -0.22[63]
10 IL6 Interleukin-6 [64] 0.18[65] [66] 2.85[67] 7.42[68] 8.89[69] [70]
11 CD3E T-cell surface glycoprotein CD3 epsilon chain [71] -0.24[72] [73] 2.29[74] [75] [76] -0.62[77]
12 CD247 T-cell surface glycoprotein CD3 zeta chain [78] 3.75[79] 3.55[80] 0.64[81] 4.76[82] 2.33[83] -0.03[84]
13 LCK Tyrosine-protein kinase Lck [85] 11.40[86] 11.95[87] 0.54[88] 3.19[89] 1.94[90] 1.22[91]
14 CD8A T-cell surface glycoprotein CD8 alpha chain [92] 7.99[93] 4.71[94] 8.43[95] 3.59[96] 3.91[97] 0.83[98]
15 CD3G T-cell surface glycoprotein CD3 gamma chain [99] 5.03[100] 6.26[101] 3.79[102] 3.66[103] 3.21[104] -0.35[105]
16 CD2 T-cell surface antigen CD2 [106] 2.66[107] [108] [109] [110] [111] 0.54[112]
17 ZAP70 Tyrosine-protein kinase ZAP-70 [113] 9.62[114] 10.31[115] 2.68[116] 2.73[117] 3.03[118] 2.15[119]
18 MMP25 Matrix metalloproteinase-25 [120] 8.70[121] 9.48[122] 8.20[123] 9.39[124] 8.84[125] 3.14[126]
19 CD8B T-cell surface glycoprotein CD8 beta chain [127] 9.61[128] 8.45[129] 15.63[130] [131] 5.22[132] 3.11[133]
20 CXCL8 Interleukin-8 [134] [135] [136] [137] [138] [139] [140]
21 PRG3 Proteoglycan 3 [141] [142] [143] [144] [145] [146] [147]
[1]
ref_hepatocyte CRP
Mean 3.33e+03
Standard deviation 5.7e+03
Values 7.6e+02 2.4e+03 1.3e+04 0 4.8
[2]
HepG2 CRP
Mean 0
Standard deviation 0
Values 0 0
[3]
HepG2.C3A CRP
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 CRP
Mean 0.0466
Standard deviation 0.01
Values 0.037 0.045 0.057
[5]
SNU475 CRP
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE CRP
Mean 0.0547
Standard deviation 0.04
Values 0.083 0.027
[7]
liver CRP
Mean 4.8e+03
Standard deviation 4.3e+03
Values 1.6e+03 3.6e+03 2.9e+03 1.1e+04
[8]
ref_hepatocyte LBP
Mean 424
Standard deviation 5.3e+02
Values 86 7.2e+02 1.2e+03 0.39 1e+02
[9]
HepG2 LBP
Mean 0.29
Standard deviation 0.045
Values 0.32 0.26
[10]
HepG2.C3A LBP
Mean 0.0317
Standard deviation 0.031
Values 0.054 0.0097
[11]
HuH.7 LBP
Mean 5.83
Standard deviation 7.8
Values 1.3 15 1.3
[12]
SNU475 LBP
Mean 0.0865
Standard deviation 0.057
Values 0.13 0.046
[13]
THLE LBP
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[14]
liver LBP
Mean 630
Standard deviation 2.6e+02
Values 5e+02 4.9e+02 5e+02 1e+03
[15]
ref_hepatocyte HLA-DRA
Mean 28.7
Standard deviation 43
Values 6.7 1e+02 33 0 1.6
[16]
HepG2 HLA-DRA
Mean 0.00643
Standard deviation 0.0091
Values 0.013 0
[17]
HepG2.C3A HLA-DRA
Mean 0
Standard deviation 0
Values 0 0
[18]
HuH.7 HLA-DRA
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[19]
SNU475 HLA-DRA
Mean 0.979
Standard deviation 0.57
Values 1.4 0.58
[20]
THLE HLA-DRA
Mean 0.289
Standard deviation 0.31
Values 0.51 0.069
[21]
liver HLA-DRA
Mean 27.5
Standard deviation 9.7
Values 16 26 29 39
[22]
ref_hepatocyte HLA-DRB1
Mean 19
Standard deviation 28
Values 4 66 24 0 0.7
[23]
HepG2 HLA-DRB1
Mean 0.121
Standard deviation 0.017
Values 0.13 0.11
[24]
HepG2.C3A HLA-DRB1
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 HLA-DRB1
Mean 0
Standard deviation 0
Values 0 0 0
[26]
SNU475 HLA-DRB1
Mean 0.506
Standard deviation 0.45
Values 0.83 0.19
[27]
THLE HLA-DRB1
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[28]
liver HLA-DRB1
Mean 8.55
Standard deviation 3.8
Values 4.6 6.5 10 13
[29]
ref_hepatocyte CD4
Mean 14.9
Standard deviation 25
Values 1.1 59 15 0.42 0
[30]
HepG2 CD4
Mean 0.611
Standard deviation 0.26
Values 0.8 0.42
[31]
HepG2.C3A CD4
Mean 2.47
Standard deviation 0.32
Values 2.7 2.2
[32]
HuH.7 CD4
Mean 0.383
Standard deviation 0.15
Values 0.32 0.55 0.28
[33]
SNU475 CD4
Mean 0.157
Standard deviation 0.028
Values 0.14 0.18
[34]
THLE CD4
Mean 0.0423
Standard deviation 0.0071
Values 0.047 0.037
[35]
liver CD4
Mean 20
Standard deviation 8
Values 13 15 22 30
[36]
ref_hepatocyte IGLL1
Mean 9.95
Standard deviation 15
Values 3.8 36 9.6 0 0
[37]
HepG2 IGLL1
Mean 0
Standard deviation 0
Values 0 0
[38]
HepG2.C3A IGLL1
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 IGLL1
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[40]
SNU475 IGLL1
Mean 0
Standard deviation 0
Values 0 0
[41]
THLE IGLL1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[42]
liver IGLL1
Mean 0.0284
Standard deviation 0.034
Values 0.013 0 0.024 0.077
[43]
ref_hepatocyte HLA-DRB5
Mean 7.06
Standard deviation 9.7
Values 1.2 22 12 0 0.3
[44]
HepG2 HLA-DRB5
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[45]
HepG2.C3A HLA-DRB5
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 HLA-DRB5
Mean 0
Standard deviation 0
Values 0 0 0
[47]
SNU475 HLA-DRB5
Mean 0.0395
Standard deviation 0.023
Values 0.056 0.023
[48]
THLE HLA-DRB5
Mean 0
Standard deviation 0
Values 0 0
[49]
liver HLA-DRB5
Mean 0.174
Standard deviation 0.13
Values 0.33 0.21 0.024 0.13
[50]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 0.23 5.5 2.6 2.2 0.039
[51]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 8.4 9.4
[52]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[53]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.5 4.8 8.9
[54]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 8.9 12
[55]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[56]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 5 4.4 8.9 5.1
[57]
ref_hepatocyte NKRF
Mean 2.01
Standard deviation 0.6
Values 2.7 2 1.1 2.3 2
[58]
HepG2 NKRF
Mean 5.22
Standard deviation 1.3
Values 6.1 4.3
[59]
HepG2.C3A NKRF
Mean 5.57
Standard deviation 0.12
Values 5.7 5.5
[60]
HuH.7 NKRF
Mean 12.8
Standard deviation 2.1
Values 13 11 15
[61]
SNU475 NKRF
Mean 8.52
Standard deviation 1.1
Values 9.3 7.7
[62]
THLE NKRF
Mean 8.24
Standard deviation 1
Values 7.5 9
[63]
liver NKRF
Mean 2.47
Standard deviation 0.52
Values 2.4 3 1.8 2.7
[64]
ref_hepatocyte IL6
Mean 1.35
Standard deviation 2.5
Values 5.9 0.28 0.6 0 0
[65]
HepG2 IL6
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[66]
HepG2.C3A IL6
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 IL6
Mean 0.0895
Standard deviation 0.012
Values 0.1 0.083 0.082
[68]
SNU475 IL6
Mean 1.37
Standard deviation 1.7
Values 2.6 0.15
[69]
THLE IL6
Mean 8.81
Standard deviation 1.5
Values 7.7 9.9
[70]
liver IL6
Mean 0
Standard deviation 0
Values 0 0 0 0
[71]
ref_hepatocyte CD3E
Mean 0.605
Standard deviation 0.94
Values 0 2.2 0.75 0 0.078
[72]
HepG2 CD3E
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[73]
HepG2.C3A CD3E
Mean 0
Standard deviation 0
Values 0 0
[74]
HuH.7 CD3E
Mean 0.0273
Standard deviation 0.032
Values 0.0094 0.064 0.0082
[75]
SNU475 CD3E
Mean 0
Standard deviation 0
Values 0 0
[76]
THLE CD3E
Mean 0
Standard deviation 0
Values 0 0
[77]
liver CD3E
Mean 0.564
Standard deviation 0.34
Values 0.36 0.21 0.94 0.74
[78]
ref_hepatocyte CD247
Mean 0.369
Standard deviation 0.47
Values 0.22 1.1 0.51 0 0
[79]
HepG2 CD247
Mean 0.0279
Standard deviation 0.015
Values 0.039 0.017
[80]
HepG2.C3A CD247
Mean 0.0156
Standard deviation 0.0083
Values 0.021 0.0097
[81]
HuH.7 CD247
Mean 0.00526
Standard deviation 0.0048
Values 0.0094 0.0064 0
[82]
SNU475 CD247
Mean 0.0593
Standard deviation 0.038
Values 0.086 0.032
[83]
THLE CD247
Mean 0.0254
Standard deviation 0.0059
Values 0.03 0.021
[84]
liver CD247
Mean 0.518
Standard deviation 0.17
Values 0.58 0.51 0.28 0.69
[85]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.49 0.99 0 0.11 0
[86]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 1.7 8
[87]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.7 4.4
[88]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[89]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.025 0.0093
[90]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[91]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 0.91 0.49 1.2 1.7
[92]
ref_hepatocyte CD8A
Mean 0.274
Standard deviation 0.36
Values 0.2 0.91 0.095 0.082 0.078
[93]
HepG2 CD8A
Mean 0.392
Standard deviation 0.19
Values 0.26 0.53
[94]
HepG2.C3A CD8A
Mean 0.0258
Standard deviation 0.009
Values 0.032 0.019
[95]
HuH.7 CD8A
Mean 0.869
Standard deviation 0.17
Values 0.86 1 0.71
[96]
SNU475 CD8A
Mean 0.0196
Standard deviation 0.0081
Values 0.025 0.014
[97]
THLE CD8A
Mean 0.0565
Standard deviation 0.012
Values 0.065 0.048
[98]
liver CD8A
Mean 0.696
Standard deviation 0.6
Values 0.19 0.24 0.92 1.4
[99]
ref_hepatocyte CD3G
Mean 0.262
Standard deviation 0.26
Values 0 0.54 0.49 0.28 0
[100]
HepG2 CD3G
Mean 0.048
Standard deviation 0.013
Values 0.039 0.057
[101]
HepG2.C3A CD3G
Mean 0.0721
Standard deviation 0.019
Values 0.086 0.058
[102]
HuH.7 CD3G
Mean 0.0331
Standard deviation 0.0052
Values 0.028 0.039 0.033
[103]
SNU475 CD3G
Mean 0.0196
Standard deviation 0.0081
Values 0.025 0.014
[104]
THLE CD3G
Mean 0.0331
Standard deviation 0.013
Values 0.024 0.043
[105]
liver CD3G
Mean 0.293
Standard deviation 0.14
Values 0.34 0.46 0.14 0.23
[106]
ref_hepatocyte CD2
Mean 0.242
Standard deviation 0.49
Values 0 1.1 0.095 0 0
[107]
HepG2 CD2
Mean 0.00858
Standard deviation 0.012
Values 0.017 0
[108]
HepG2.C3A CD2
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 CD2
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 CD2
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE CD2
Mean 0
Standard deviation 0
Values 0 0
[112]
liver CD2
Mean 0.504
Standard deviation 0.32
Values 0.26 0.29 0.52 0.95
[113]
ref_hepatocyte ZAP70
Mean 0.182
Standard deviation 0.23
Values 0 0.57 0.2 0.14 0
[114]
HepG2 ZAP70
Mean 0.806
Standard deviation 0.62
Values 0.37 1.2
[115]
HepG2.C3A ZAP70
Mean 0.835
Standard deviation 0.029
Values 0.82 0.86
[116]
HuH.7 ZAP70
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[117]
SNU475 ZAP70
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[118]
THLE ZAP70
Mean 0.0204
Standard deviation 0.021
Values 0.035 0.0053
[119]
liver ZAP70
Mean 1.16
Standard deviation 0.36
Values 1.3 0.87 0.85 1.6
[120]
ref_hepatocyte MMP25
Mean 0.0818
Standard deviation 0.066
Values 0.14 0.15 0.043 0 0.067
[121]
HepG2 MMP25
Mean 0.191
Standard deviation 0.027
Values 0.21 0.17
[122]
HepG2.C3A MMP25
Mean 0.21
Standard deviation 0.13
Values 0.12 0.3
[123]
HuH.7 MMP25
Mean 0.221
Standard deviation 0.1
Values 0.16 0.34 0.16
[124]
SNU475 MMP25
Mean 0.327
Standard deviation 0.089
Values 0.26 0.39
[125]
THLE MMP25
Mean 0.512
Standard deviation 0.15
Values 0.62 0.41
[126]
liver MMP25
Mean 1.04
Standard deviation 0.79
Values 2.2 0.64 0.61 0.67
[127]
ref_hepatocyte CD8B
Mean 0.0163
Standard deviation 0.036
Values 0 0.081 0 0 0
[128]
HepG2 CD8B
Mean 0.0715
Standard deviation 0.044
Values 0.1 0.04
[129]
HepG2.C3A CD8B
Mean 0.0204
Standard deviation 0.0014
Values 0.021 0.019
[130]
HuH.7 CD8B
Mean 7.57
Standard deviation 1.4
Values 9.2 6.5 7
[131]
SNU475 CD8B
Mean 0
Standard deviation 0
Values 0 0
[132]
THLE CD8B
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[133]
liver CD8B
Mean 0.201
Standard deviation 0.15
Values 0.053 0.13 0.21 0.41
[134]
ref_hepatocyte CXCL8
Missing
[135]
HepG2 CXCL8
Missing
[136]
HepG2.C3A CXCL8
Missing
[137]
HuH.7 CXCL8
Missing
[138]
SNU475 CXCL8
Missing
[139]
THLE CXCL8
Missing
[140]
liver CXCL8
Missing
[141]
ref_hepatocyte PRG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 PRG3
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A PRG3
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 PRG3
Mean 0
Standard deviation 0
Values 0 0 0
[145]
SNU475 PRG3
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE PRG3
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[147]
liver PRG3
Mean 0.00642
Standard deviation 0.013
Values 0 0 0 0.026