WP_OXIDATION_BY_CYTOCHROME_P450 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2E1 Cytochrome P450 2E1 [1] -11.01[2] -11.43[3] -7.48[4] -11.71[5] -10.29[6] -0.68[7]
2 CYB5A Cytochrome b5 [8] -1.02[9] -0.83[10] -1.31[11] -0.90[12] -1.62[13] -1.00[14]
3 CYP2C8 Cytochrome P450 2C8 [15] -13.01[16] -8.55[17] -5.65[18] -8.79[19] [20] 0.24[21]
4 CYP2C9 Cytochrome P450 2C9 [22] [23] -13.47[24] -5.86[25] -11.48[26] -10.82[27] 0.74[28]
5 CYP3A4 Cytochrome P450 3A4 [29] -8.26[30] -8.66[31] -9.67[32] -11.80[33] -10.39[34] 0.45[35]
6 CYP2A6 Cytochrome P450 2A6 [36] -14.38[37] [38] -6.11[39] -8.55[40] -11.13[41] -1.89[42]
7 CYP3A5 Cytochrome P450 3A5 [43] -3.33[44] -1.38[45] -3.43[46] -4.37[47] -6.73[48] 0.82[49]
8 CYP27A1 Sterol 26-hydroxylase, mitochondrial [50] 1.40[51] 1.91[52] -0.47[53] 0.16[54] -1.53[55] -0.19[56]
9 CYP4A11 Cytochrome P450 4A11 [57] -11.18[58] -8.83[59] -10.00[60] -7.61[61] -8.77[62] 0.60[63]
10 POR NADPH--cytochrome P450 reductase [64] 2.56[65] 2.86[66] 2.33[67] 2.94[68] 1.78[69] 1.09[70]
11 CYP1A2 Cytochrome P450 1A2 [71] -7.44[72] -6.42[73] -6.37[74] -5.36[75] -5.93[76] -1.93[77]
12 CYP51A1 Lanosterol 14-alpha demethylase [78] 0.77[79] 2.90[80] 3.53[81] 2.29[82] 1.81[83] 0.53[84]
13 CYP2B6 Cytochrome P450 2B6 [85] -6.16[86] -3.00[87] -0.93[88] -6.35[89] -7.50[90] 2.12[91]
14 CYP1A1 Cytochrome P450 1A1 [92] -0.98[93] -2.85[94] 1.52[95] -0.77[96] -1.45[97] -6.07[98]
15 CYP2C18 Cytochrome P450 2C18 [99] -7.98[100] -9.74[101] -3.19[102] -8.62[103] -6.83[104] -0.73[105]
16 CYB5R3 NADH-cytochrome b5 reductase 3 [106] 4.13[107] 4.13[108] 4.30[109] 4.32[110] 4.55[111] 0.35[112]
17 CYP2D6 Cytochrome P450 2D6 [113] -4.42[114] -2.22[115] -4.04[116] -4.86[117] -5.52[118] 0.95[119]
18 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [120] -4.74[121] -2.47[122] -5.69[123] -5.26[124] -7.23[125] 2.18[126]
19 CYP4F2 Phylloquinone omega-hydroxylase CYP4F2 [127] -3.14[128] 0.20[129] -10.79[130] -8.83[131] -7.08[132] 0.54[133]
20 CYP3A7 Cytochrome P450 3A7 [134] -3.44[135] -1.45[136] -5.48[137] [138] -8.19[139] -1.95[140]
21 CYP2J2 Cytochrome P450 2J2 [141] -1.92[142] -2.19[143] 1.62[144] -3.46[145] -2.13[146] -0.01[147]
22 CYB5B Cytochrome b5 type B [148] 4.57[149] 4.88[150] 5.19[151] 4.66[152] 4.75[153] -0.60[154]
23 CYP2C19 Cytochrome P450 2C19 [155] [156] [157] -3.01[158] -9.17[159] -9.12[160] 1.30[161]
24 CYP2A7 Cytochrome P450 2A7 [162] [163] [164] -1.52[165] -7.15[166] [167] -2.04[168]
25 CYB5R1 NADH-cytochrome b5 reductase 1 [169] 1.92[170] 1.46[171] 2.58[172] 4.23[173] 3.48[174] -0.86[175]
26 CYP4F11 Phylloquinone omega-hydroxylase CYP4F11 [176] 0.95[177] 0.25[178] -6.34[179] 3.61[180] -6.58[181] 0.47[182]
27 CYP4F3 Docosahexaenoic acid omega-hydroxylase CYP4F3 [183] 0.02[184] 0.66[185] 2.63[186] 0.21[187] -6.08[188] 1.91[189]
28 CYP4V2 Cytochrome P450 4V2 [190] 0.24[191] 1.71[192] 0.48[193] 0.85[194] 1.25[195] 1.48[196]
29 CYP4F12 Cytochrome P450 4F12 [197] 0.78[198] 1.84[199] 3.72[200] -0.22[201] -4.42[202] -0.08[203]
30 CYP39A1 24-hydroxycholesterol 7-alpha-hydroxylase [204] -1.58[205] -2.04[206] 3.31[207] -0.21[208] 1.60[209] 0.20[210]
31 CYP7A1 Cholesterol 7-alpha-monooxygenase [211] -0.86[212] -3.47[213] -6.30[214] -5.25[215] [216] -3.23[217]
32 CYP4A22 Cytochrome P450 4A22 [218] [219] [220] [221] [222] [223] 1.99[224]
33 CYP2R1 Vitamin D 25-hydroxylase [225] -0.50[226] 1.02[227] 3.94[228] 3.39[229] 2.74[230] -1.15[231]
34 CYP4F22 Cytochrome P450 4F22 [232] -2.40[233] [234] -6.98[235] -5.24[236] -3.58[237] -1.25[238]
35 CYP1B1 Cytochrome P450 1B1 [239] -3.57[240] -3.28[241] 1.53[242] 6.23[243] 8.69[244] 0.74[245]
36 CYB5R4 Cytochrome b5 reductase 4 [246] 4.00[247] 3.96[248] 4.82[249] 4.60[250] 5.49[251] 0.18[252]
37 CYB5R2 NADH-cytochrome b5 reductase 2 [253] -0.44[254] -2.21[255] 3.39[256] 2.57[257] 3.47[258] -2.61[259]
38 CYP20A1 Cytochrome P450 20A1 [260] 5.09[261] 5.29[262] 5.40[263] 5.93[264] 6.28[265] 3.13[266]
39 CYP3A43 Cytochrome P450 3A43 [267] -1.37[268] 1.24[269] 1.76[270] [271] -5.56[272] 1.11[273]
40 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [274] -4.55[275] -3.54[276] [277] -4.31[278] -0.72[279] 2.00[280]
41 CYP19A1 Aromatase [281] 5.41[282] 6.16[283] 0.41[284] 3.07[285] 0.48[286] -6.61[287]
42 CYP2U1 Cytochrome P450 2U1 [288] 3.66[289] -0.42[290] 0.48[291] 5.95[292] 6.60[293] 1.80[294]
43 CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial [295] 2.82[296] 0.03[297] [298] 1.46[299] 5.37[300] 0.19[301]
44 CYP2W1 Cytochrome P450 2W1 [302] 7.18[303] 8.81[304] 3.43[305] 1.29[306] 0.74[307] -4.30[308]
45 CYP2S1 Cytochrome P450 2S1 [309] 6.39[310] 4.99[311] 4.87[312] 5.90[313] 5.84[314] -0.92[315]
46 CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [316] 11.62[317] 6.48[318] 1.54[319] 8.83[320] 1.88[321] -7.37[322]
47 CYP4X1 Cytochrome P450 4X1 [323] -2.62[324] -3.87[325] [326] -0.41[327] 0.66[328] 1.59[329]
48 CYP26A1 Cytochrome P450 26A1 [330] 6.65[331] 0.54[332] 4.78[333] 4.87[334] -0.96[335] 0.73[336]
49 CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase [337] 0.74[338] 4.52[339] 1.78[340] -1.02[341] -1.11[342] 1.37[343]
50 CYP2A13 Cytochrome P450 2A13 [344] [345] [346] [347] [348] [349] -0.79[350]
51 CYP27C1 Cytochrome P450 27C1 [351] 2.94[352] 3.37[353] 3.99[354] 5.67[355] 4.10[356] 0.51[357]
52 CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [358] 6.16[359] 7.32[360] 7.41[361] 5.91[362] 6.50[363] 1.39[364]
53 CYP46A1 Cholesterol 24-hydroxylase [365] -0.31[366] 0.76[367] 0.44[368] 2.16[369] 3.22[370] 1.98[371]
54 CYP2F1 Cytochrome P450 2F1 [372] 2.71[373] 0.81[374] 5.82[375] 6.16[376] 4.91[377] 0.70[378]
55 CYP4Z1 Cytochrome P450 4Z1 [379] [380] [381] [382] [383] [384] 1.90[385]
56 CYP26B1 Cytochrome P450 26B1 [386] 8.37[387] 5.04[388] 12.95[389] 11.42[390] 10.52[391] 5.26[392]
57 CYP4F8 Cytochrome P450 4F8 [393] [394] [395] [396] [397] [398] [399]
58 CYP2G1P Putative inactive cytochrome P450 2G1 [400] [401] [402] [403] [404] [405] [406]
59 CYP26C1 Cytochrome P450 26C1 [407] [408] [409] [410] [411] [412] [413]
60 CYP11B1 Cytochrome P450 11B1, mitochondrial [414] [415] [416] [417] [418] [419] [420]
61 CYP11B2 Cytochrome P450 11B2, mitochondrial [421] [422] [423] [424] [425] [426] [427]
62 CYP4B1 Cytochrome P450 4B1 [428] [429] [430] [431] [432] [433] [434]
63 MIR4651 [435] [436] [437] [438] [439] [440] [441]
[1]
ref_hepatocyte CYP2E1
Mean 1.39e+03
Standard deviation 1.9e+03
Values 90 4.1e+03 2.7e+03 0 4.6
[2]
HepG2 CYP2E1
Mean 0.133
Standard deviation 0.1
Values 0.06 0.21
[3]
HepG2.C3A CYP2E1
Mean 0.107
Standard deviation 0.15
Values 0 0.21
[4]
HuH.7 CYP2E1
Mean 0.975
Standard deviation 0.29
Values 0.99 1.3 0.67
[5]
SNU475 CYP2E1
Mean 0.0289
Standard deviation 0.005
Values 0.025 0.032
[6]
THLE CYP2E1
Mean 0.0955
Standard deviation 0.082
Values 0.15 0.037
[7]
liver CYP2E1
Mean 1.49e+03
Standard deviation 8.2e+02
Values 6.9e+02 1e+03 2.6e+03 1.7e+03
[8]
ref_hepatocyte CYB5A
Mean 485
Standard deviation 5e+02
Values 86 1.2e+03 8.6e+02 1.7e+02 1.3e+02
[9]
HepG2 CYB5A
Mean 47.2
Standard deviation 8.3
Values 53 41
[10]
HepG2.C3A CYB5A
Mean 58.3
Standard deviation 3.9
Values 61 55
[11]
HuH.7 CYB5A
Mean 24.7
Standard deviation 6.7
Values 32 20 22
[12]
SNU475 CYB5A
Mean 18.2
Standard deviation 3.3
Values 16 21
[13]
THLE CYB5A
Mean 13.5
Standard deviation 0.22
Values 14 13
[14]
liver CYB5A
Mean 416
Standard deviation 2.9e+02
Values 92 2.7e+02 5.6e+02 7.4e+02
[15]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 19 9.1e+02 7.1e+02 0 1.2
[16]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.0043 0.011
[17]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.24 0.14
[18]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.3 2 0.16
[19]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.066 0.037
[20]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[21]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 2e+02 6.2e+02 6.8e+02 1.2e+03
[22]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 21 9.2e+02 4.7e+02 0.064 20
[23]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[24]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[25]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[26]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[27]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[28]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 2.9e+02 6.1e+02 8.6e+02 1.5e+03
[29]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 11 9.6e+02 3.2e+02 0.24 11
[30]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.24 0.097
[31]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.2 0.068
[32]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.047 0.064 0.0082
[33]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[34]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[35]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 49 6.4e+02 4.3e+02 1.3e+03
[36]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 38 5.5e+02 5.6e+02 0 4.6
[37]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[38]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[39]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.12 1 0.11
[40]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.025 0.06
[41]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[42]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 13 1.8e+02 29 2.1e+02
[43]
ref_hepatocyte CYP3A5
Mean 139
Standard deviation 1.6e+02
Values 35 3.9e+02 2e+02 22 55
[44]
HepG2 CYP3A5
Mean 2.75
Standard deviation 2.1
Values 4.2 1.3
[45]
HepG2.C3A CYP3A5
Mean 11.4
Standard deviation 3.8
Values 8.7 14
[46]
HuH.7 CYP3A5
Mean 1.63
Standard deviation 1.6
Values 0.83 3.5 0.58
[47]
SNU475 CYP3A5
Mean 0.471
Standard deviation 0.12
Values 0.39 0.56
[48]
THLE CYP3A5
Mean 0.113
Standard deviation 0.032
Values 0.14 0.09
[49]
liver CYP3A5
Mean 424
Standard deviation 3.2e+02
Values 2.8e+02 2.7e+02 9e+02 2.5e+02
[50]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 18 3.7e+02 2.1e+02 62 8
[51]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 82 59
[52]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 90 1.3e+02
[53]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 8.9 21 7.2
[54]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 9.4 12
[55]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[56]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 1.1e+02 1.2e+02 3.3e+02 2.5e+02
[57]
ref_hepatocyte CYP4A11
Mean 109
Standard deviation 1.6e+02
Values 4 3.4e+02 2e+02 0 0
[58]
HepG2 CYP4A11
Mean 0.0093
Standard deviation 0.005
Values 0.013 0.0057
[59]
HepG2.C3A CYP4A11
Mean 0.0511
Standard deviation 0.0036
Values 0.054 0.049
[60]
HuH.7 CYP4A11
Mean 0.0135
Standard deviation 0.0098
Values 0.0094 0.0064 0.025
[61]
SNU475 CYP4A11
Mean 0.039
Standard deviation 0.0093
Values 0.046 0.032
[62]
THLE CYP4A11
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[63]
liver CYP4A11
Mean 286
Standard deviation 2.2e+02
Values 1.3e+02 87 5.7e+02 3.6e+02
[64]
ref_hepatocyte POR
Mean 97
Standard deviation 75
Values 26 1.3e+02 2.1e+02 90 32
[65]
HepG2 POR
Mean 113
Standard deviation 40
Values 85 1.4e+02
[66]
HepG2.C3A POR
Mean 150
Standard deviation 87
Values 88 2.1e+02
[67]
HuH.7 POR
Mean 61.3
Standard deviation 8.5
Values 56 71 57
[68]
SNU475 POR
Mean 52.1
Standard deviation 1.3
Values 53 51
[69]
THLE POR
Mean 28.6
Standard deviation 2.7
Values 27 31
[70]
liver POR
Mean 355
Standard deviation 1.6e+02
Values 2.3e+02 3.2e+02 2.7e+02 5.9e+02
[71]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[72]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[73]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[74]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[75]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[76]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[77]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[78]
ref_hepatocyte CYP51A1
Mean 63
Standard deviation 38
Values 38 46 27 1.2e+02 88
[79]
HepG2 CYP51A1
Mean 21.2
Standard deviation 5.5
Values 25 17
[80]
HepG2.C3A CYP51A1
Mean 99.9
Standard deviation 49
Values 66 1.3e+02
[81]
HuH.7 CYP51A1
Mean 91.5
Standard deviation 23
Values 78 1.2e+02 79
[82]
SNU475 CYP51A1
Mean 21.5
Standard deviation 2.5
Values 20 23
[83]
THLE CYP51A1
Mean 19
Standard deviation 1.2
Values 18 20
[84]
liver CYP51A1
Mean 156
Standard deviation 52
Values 1.5e+02 1.8e+02 89 2.1e+02
[85]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 12 1e+02 1.3e+02 0 4.1
[86]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.034 0.24
[87]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 0.92 1.7
[88]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 1.9 5.9 2.1
[89]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.071 0.014
[90]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[91]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 7.4 3.2e+02 23 1.1e+03
[92]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 0.06 82 17 77 43
[93]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 2.6 6.2
[94]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.2 1.4
[95]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 17 17 14
[96]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 3.1 0.49
[97]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[98]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.8 0.47 1.2 0.92
[99]
ref_hepatocyte CYP2C18
Mean 43
Standard deviation 35
Values 18 56 51 0 90
[100]
HepG2 CYP2C18
Mean 0.0336
Standard deviation 0.017
Values 0.021 0.046
[101]
HepG2.C3A CYP2C18
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[102]
HuH.7 CYP2C18
Mean 0.593
Standard deviation 0.1
Values 0.53 0.71 0.53
[103]
SNU475 CYP2C18
Mean 0.0076
Standard deviation 0.011
Values 0.015 0
[104]
THLE CYP2C18
Mean 0.0325
Standard deviation 0.029
Values 0.012 0.053
[105]
liver CYP2C18
Mean 44.5
Standard deviation 13
Values 31 57 36 54
[106]
ref_hepatocyte CYB5R3
Mean 42.2
Standard deviation 22
Values 57 46 68 15 25
[107]
HepG2 CYB5R3
Mean 146
Standard deviation 25
Values 1.3e+02 1.6e+02
[108]
HepG2.C3A CYB5R3
Mean 157
Standard deviation 66
Values 1.1e+02 2e+02
[109]
HuH.7 CYB5R3
Mean 105
Standard deviation 6.2
Values 1e+02 1e+02 1.1e+02
[110]
SNU475 CYB5R3
Mean 58.8
Standard deviation 13
Values 49 68
[111]
THLE CYB5R3
Mean 85
Standard deviation 17
Values 73 97
[112]
liver CYB5R3
Mean 92.7
Standard deviation 83
Values 28 15 1.7e+02 1.5e+02
[113]
ref_hepatocyte CYP2D6
Mean 41.3
Standard deviation 55
Values 3.7 87 1.1e+02 0.24 0.47
[114]
HepG2 CYP2D6
Mean 0.382
Standard deviation 0.03
Values 0.4 0.36
[115]
HepG2.C3A CYP2D6
Mean 1.89
Standard deviation 1
Values 1.2 2.6
[116]
HuH.7 CYP2D6
Mean 0.314
Standard deviation 0.087
Values 0.31 0.4 0.23
[117]
SNU475 CYP2D6
Mean 0.0992
Standard deviation 0.004
Values 0.096 0.1
[118]
THLE CYP2D6
Mean 0.0775
Standard deviation 0.049
Values 0.11 0.043
[119]
liver CYP2D6
Mean 137
Standard deviation 1.2e+02
Values 57 53 3.1e+02 1.3e+02
[120]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 6.4 86 79 1.2 0.33
[121]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.4 0.11
[122]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 0.98 1.7
[123]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.066 0.096 0.09
[124]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.066 0.06
[125]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[126]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 2.2e+02 1.3e+02 4.2e+02 3e+02
[127]
ref_hepatocyte CYP4F2
Mean 30.2
Standard deviation 38
Values 11 87 51 1.2 0.054
[128]
HepG2 CYP4F2
Mean 0.677
Standard deviation 0.5
Values 0.32 1
[129]
HepG2.C3A CYP4F2
Mean 7.41
Standard deviation 4.8
Values 4 11
[130]
HuH.7 CYP4F2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[131]
SNU475 CYP4F2
Mean 0.00464
Standard deviation 0.0066
Values 0 0.0093
[132]
THLE CYP4F2
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[133]
liver CYP4F2
Mean 75.6
Standard deviation 42
Values 36 50 86 1.3e+02
[134]
ref_hepatocyte CYP3A7
Mean 29.1
Standard deviation 41
Values 5 32 1e+02 8.7 0.12
[135]
HepG2 CYP3A7
Mean 0.531
Standard deviation 0.38
Values 0.8 0.26
[136]
HepG2.C3A CYP3A7
Mean 2.26
Standard deviation 0.013
Values 2.3 2.3
[137]
HuH.7 CYP3A7
Mean 0.0822
Standard deviation 0.074
Values 0.047 0.17 0.033
[138]
SNU475 CYP3A7
Mean 0
Standard deviation 0
Values 0 0
[139]
THLE CYP3A7
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[140]
liver CYP3A7
Mean 13
Standard deviation 12
Values 5.1 5.2 30 11
[141]
ref_hepatocyte CYP2J2
Mean 23.2
Standard deviation 23
Values 9.9 51 44 1.9 9.2
[142]
HepG2 CYP2J2
Mean 1.21
Standard deviation 0.23
Values 1 1.4
[143]
HepG2.C3A CYP2J2
Mean 1.08
Standard deviation 0.51
Values 0.72 1.4
[144]
HuH.7 CYP2J2
Mean 8.98
Standard deviation 0.32
Values 9.3 9 8.6
[145]
SNU475 CYP2J2
Mean 0.147
Standard deviation 0.13
Values 0.24 0.056
[146]
THLE CYP2J2
Mean 0.454
Standard deviation 0.094
Values 0.52 0.39
[147]
liver CYP2J2
Mean 39.7
Standard deviation 21
Values 24 21 66 48
[148]
ref_hepatocyte CYB5B
Mean 20.4
Standard deviation 19
Values 9.5 9.5 7.9 53 22
[149]
HepG2 CYB5B
Mean 95.5
Standard deviation 22
Values 1.1e+02 80
[150]
HepG2.C3A CYB5B
Mean 127
Standard deviation 43
Values 1.6e+02 97
[151]
HuH.7 CYB5B
Mean 93.6
Standard deviation 26
Values 1.1e+02 64 1.1e+02
[152]
SNU475 CYB5B
Mean 35.8
Standard deviation 4.4
Values 33 39
[153]
THLE CYB5B
Mean 47.2
Standard deviation 2.2
Values 46 49
[154]
liver CYB5B
Mean 23
Standard deviation 8
Values 16 17 28 32
[155]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 72 18 0 5.9
[156]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[157]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.2 0.6 0.098
[159]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[160]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[161]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 38 92 65 1.3e+02
[162]
ref_hepatocyte CYP2A7
Mean 15.1
Standard deviation 22
Values 11 12 52 0 0.06
[163]
HepG2 CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[164]
HepG2.C3A CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 CYP2A7
Mean 0.663
Standard deviation 0.76
Values 0.3 1.5 0.16
[166]
SNU475 CYP2A7
Mean 0.00739
Standard deviation 0.0039
Values 0.01 0.0046
[167]
THLE CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[168]
liver CYP2A7
Mean 6.31
Standard deviation 5.5
Values 1.4 13 2 9
[169]
ref_hepatocyte CYB5R1
Mean 14.8
Standard deviation 8.1
Values 12 21 25 5 11
[170]
HepG2 CYB5R1
Mean 11.1
Standard deviation 1.1
Values 10 12
[171]
HepG2.C3A CYB5R1
Mean 8.69
Standard deviation 1.5
Values 7.6 9.7
[172]
HuH.7 CYB5R1
Mean 11.1
Standard deviation 0.39
Values 12 11 11
[173]
SNU475 CYB5R1
Mean 19.5
Standard deviation 0.35
Values 20 19
[174]
THLE CYB5R1
Mean 14.2
Standard deviation 1.4
Values 13 15
[175]
liver CYB5R1
Mean 14.1
Standard deviation 8.1
Values 8 6.6 23 18
[176]
ref_hepatocyte CYP4F11
Mean 14.8
Standard deviation 11
Values 14 23 28 1.7 6.9
[177]
HepG2 CYP4F11
Mean 5.67
Standard deviation 2.2
Values 4.1 7.3
[178]
HepG2.C3A CYP4F11
Mean 3.76
Standard deviation 0.42
Values 3.5 4.1
[179]
HuH.7 CYP4F11
Mean 0.023
Standard deviation 0.029
Values 0.056 0.013 0
[180]
SNU475 CYP4F11
Mean 12.6
Standard deviation 0.65
Values 13 12
[181]
THLE CYP4F11
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[182]
liver CYP4F11
Mean 35.3
Standard deviation 12
Values 42 46 20 34
[183]
ref_hepatocyte CYP4F3
Mean 13.8
Standard deviation 15
Values 2.4 33 29 3.1 2
[184]
HepG2 CYP4F3
Mean 2.77
Standard deviation 0.38
Values 2.5 3
[185]
HepG2.C3A CYP4F3
Mean 4.62
Standard deviation 0.54
Values 4.2 5
[186]
HuH.7 CYP4F3
Mean 10.7
Standard deviation 7.3
Values 5.8 19 7.3
[187]
SNU475 CYP4F3
Mean 1.11
Standard deviation 0.19
Values 0.97 1.2
[188]
THLE CYP4F3
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[189]
liver CYP4F3
Mean 88.9
Standard deviation 26
Values 70 1.2e+02 68 95
[190]
ref_hepatocyte CYP4V2
Mean 11.2
Standard deviation 14
Values 1.4 36 13 1.9 3.8
[191]
HepG2 CYP4V2
Mean 2.61
Standard deviation 0.57
Values 3 2.2
[192]
HepG2.C3A CYP4V2
Mean 7.77
Standard deviation 2.1
Values 6.3 9.2
[193]
HuH.7 CYP4V2
Mean 1.95
Standard deviation 0.48
Values 1.6 2.5 1.8
[194]
SNU475 CYP4V2
Mean 1.4
Standard deviation 0.069
Values 1.4 1.5
[195]
THLE CYP4V2
Mean 2.28
Standard deviation 0.08
Values 2.3 2.2
[196]
liver CYP4V2
Mean 53.7
Standard deviation 9.2
Values 59 52 62 41
[197]
ref_hepatocyte CYP4F12
Mean 7.85
Standard deviation 7.8
Values 0.73 19 8.4 11 0.13
[198]
HepG2 CYP4F12
Mean 2.67
Standard deviation 0.39
Values 2.4 2.9
[199]
HepG2.C3A CYP4F12
Mean 5.98
Standard deviation 2.1
Values 4.5 7.5
[200]
HuH.7 CYP4F12
Mean 13
Standard deviation 3.4
Values 14 16 9.3
[201]
SNU475 CYP4F12
Mean 0.47
Standard deviation 0.47
Values 0.14 0.8
[202]
THLE CYP4F12
Mean 0.0316
Standard deviation 0.022
Values 0.047 0.016
[203]
liver CYP4F12
Mean 12.8
Standard deviation 14
Values 3.9 5.3 34 8.3
[204]
ref_hepatocyte CYP39A1
Mean 7.02
Standard deviation 11
Values 0.69 25 8.1 0.052 1.3
[205]
HepG2 CYP39A1
Mean 0.464
Standard deviation 0.049
Values 0.43 0.5
[206]
HepG2.C3A CYP39A1
Mean 0.363
Standard deviation 0.032
Values 0.39 0.34
[207]
HuH.7 CYP39A1
Mean 8.71
Standard deviation 0.36
Values 8.4 9.1 8.7
[208]
SNU475 CYP39A1
Mean 0.422
Standard deviation 0.11
Values 0.5 0.35
[209]
THLE CYP39A1
Mean 1.83
Standard deviation 0.14
Values 1.9 1.7
[210]
liver CYP39A1
Mean 13.9
Standard deviation 9.4
Values 7.1 8.3 28 13
[211]
ref_hepatocyte CYP7A1
Mean 4.03
Standard deviation 5.2
Values 0 9.7 0.69 9.8 0
[212]
HepG2 CYP7A1
Mean 0.438
Standard deviation 0.47
Values 0.77 0.11
[213]
HepG2.C3A CYP7A1
Mean 0.0774
Standard deviation 0.027
Values 0.097 0.058
[214]
HuH.7 CYP7A1
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[215]
SNU475 CYP7A1
Mean 0.00739
Standard deviation 0.0039
Values 0.01 0.0046
[216]
THLE CYP7A1
Mean 0
Standard deviation 0
Values 0 0
[217]
liver CYP7A1
Mean 0.737
Standard deviation 0.45
Values 0.079 0.94 1.1 0.82
[218]
ref_hepatocyte CYP4A22
Mean 3.13
Standard deviation 4
Values 0.49 7.8 7.2 0 0.14
[219]
HepG2 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[220]
HepG2.C3A CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[221]
HuH.7 CYP4A22
Mean 0
Standard deviation 0
Values 0 0 0
[222]
SNU475 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[223]
THLE CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[224]
liver CYP4A22
Mean 21.4
Standard deviation 17
Values 18 6.3 46 15
[225]
ref_hepatocyte CYP2R1
Mean 2.89
Standard deviation 1.8
Values 3.6 2.3 3.9 0 4.7
[226]
HepG2 CYP2R1
Mean 0.405
Standard deviation 0.2
Values 0.27 0.54
[227]
HepG2.C3A CYP2R1
Mean 1.25
Standard deviation 0.41
Values 0.95 1.5
[228]
HuH.7 CYP2R1
Mean 5.56
Standard deviation 0.93
Values 6.4 5.8 4.6
[229]
SNU475 CYP2R1
Mean 2.12
Standard deviation 0.069
Values 2.1 2.2
[230]
THLE CYP2R1
Mean 1.67
Standard deviation 0.39
Values 1.9 1.4
[231]
liver CYP2R1
Mean 2.24
Standard deviation 0.78
Values 2 1.6 3.4 2
[232]
ref_hepatocyte CYP4F22
Mean 2.74
Standard deviation 3.4
Values 8.2 1.8 3.5 0 0.23
[233]
HepG2 CYP4F22
Mean 0.103
Standard deviation 0.15
Values 0 0.21
[234]
HepG2.C3A CYP4F22
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 CYP4F22
Mean 0.00273
Standard deviation 0.0047
Values 0 0 0.0082
[236]
SNU475 CYP4F22
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[237]
THLE CYP4F22
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[238]
liver CYP4F22
Mean 1.99
Standard deviation 1.8
Values 1.1 0.59 4.7 1.6
[239]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.92 1.4 2.7 0.024 8
[240]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.03 0.057
[241]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.086 0.029
[242]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.95 1 0.87
[243]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 11 16
[244]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[245]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.2 7.4 6.9 9.5
[246]
ref_hepatocyte CYB5R4
Mean 2.59
Standard deviation 1.1
Values 1.4 2.6 1.6 3.2 4.1
[247]
HepG2 CYB5R4
Mean 8.19
Standard deviation 3.1
Values 10 6
[248]
HepG2.C3A CYB5R4
Mean 8.58
Standard deviation 4.4
Values 12 5.4
[249]
HuH.7 CYB5R4
Mean 9.21
Standard deviation 0.22
Values 9.2 9 9.4
[250]
SNU475 CYB5R4
Mean 4.39
Standard deviation 0.31
Values 4.6 4.2
[251]
THLE CYB5R4
Mean 10
Standard deviation 1.3
Values 9.1 11
[252]
liver CYB5R4
Mean 5.04
Standard deviation 1.9
Values 3.3 3.5 6.9 6.5
[253]
ref_hepatocyte CYB5R2
Mean 2.42
Standard deviation 3
Values 7.6 0.6 1.8 0.35 1.8
[254]
HepG2 CYB5R2
Mean 0.354
Standard deviation 0.11
Values 0.28 0.43
[255]
HepG2.C3A CYB5R2
Mean 0.111
Standard deviation 0.021
Values 0.097 0.13
[256]
HuH.7 CYB5R2
Mean 3.19
Standard deviation 1.7
Values 4.4 1.3 3.9
[257]
SNU475 CYB5R2
Mean 1.01
Standard deviation 0.15
Values 0.9 1.1
[258]
THLE CYB5R2
Mean 2.31
Standard deviation 0.5
Values 2 2.7
[259]
liver CYB5R2
Mean 0.683
Standard deviation 0.29
Values 0.49 0.53 0.61 1.1
[260]
ref_hepatocyte CYP20A1
Mean 1.55
Standard deviation 0.71
Values 0.62 1.9 1.4 2.5 1.3
[261]
HepG2 CYP20A1
Mean 10.5
Standard deviation 1.8
Values 12 9.2
[262]
HepG2.C3A CYP20A1
Mean 12.9
Standard deviation 0.38
Values 13 13
[263]
HuH.7 CYP20A1
Mean 8.21
Standard deviation 0.45
Values 8.1 7.9 8.7
[264]
SNU475 CYP20A1
Mean 6.58
Standard deviation 0.51
Values 6.2 6.9
[265]
THLE CYP20A1
Mean 10.4
Standard deviation 1.6
Values 9.3 12
[266]
liver CYP20A1
Mean 23.3
Standard deviation 4.4
Values 18 22 28 25
[267]
ref_hepatocyte CYP3A43
Mean 1.46
Standard deviation 2.7
Values 0 6.1 1.1 0.059 0
[268]
HepG2 CYP3A43
Mean 0.112
Standard deviation 0.061
Values 0.15 0.069
[269]
HepG2.C3A CYP3A43
Mean 0.735
Standard deviation 0.42
Values 0.44 1
[270]
HuH.7 CYP3A43
Mean 0.622
Standard deviation 0.91
Values 0.14 1.7 0.057
[271]
SNU475 CYP3A43
Mean 0
Standard deviation 0
Values 0 0
[272]
THLE CYP3A43
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[273]
liver CYP3A43
Mean 5.41
Standard deviation 4.2
Values 3.6 2.9 12 3.4
[274]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 1.1 2.7 1.2 0 2.2
[275]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.013 0.011
[276]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.043 0.0097
[277]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[278]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[279]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[280]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 12 17 6.3 4.8
[281]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 0.28 0 0 5.3 0.08
[282]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 10 8.9
[283]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 13 21
[284]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.047 0.5 0.016
[285]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 1.1 0.25
[286]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[287]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0.079 0 0 0
[288]
ref_hepatocyte CYP2U1
Mean 1.09
Standard deviation 0.48
Values 0.46 1.7 1.4 0.81 1.1
[289]
HepG2 CYP2U1
Mean 2.73
Standard deviation 0.62
Values 3.2 2.3
[290]
HepG2.C3A CYP2U1
Mean 0.173
Standard deviation 0.15
Values 0.28 0.068
[291]
HuH.7 CYP2U1
Mean 0.192
Standard deviation 0.045
Values 0.24 0.17 0.16
[292]
SNU475 CYP2U1
Mean 4.71
Standard deviation 1
Values 4 5.4
[293]
THLE CYP2U1
Mean 9.13
Standard deviation 0.16
Values 9 9.2
[294]
liver CYP2U1
Mean 6.54
Standard deviation 1.6
Values 5 8.3 5.5 7.4
[295]
ref_hepatocyte CYP11A1
Mean 0.602
Standard deviation 0.44
Values 0.44 1.3 0.59 0.18 0.47
[296]
HepG2 CYP11A1
Mean 0.843
Standard deviation 0.49
Values 0.49 1.2
[297]
HepG2.C3A CYP11A1
Mean 0.131
Standard deviation 0.049
Values 0.097 0.17
[298]
HuH.7 CYP11A1
Mean 0
Standard deviation 0
Values 0 0 0
[299]
SNU475 CYP11A1
Mean 0.115
Standard deviation 0.045
Values 0.15 0.083
[300]
THLE CYP11A1
Mean 2.14
Standard deviation 0.87
Values 2.8 1.5
[301]
liver CYP11A1
Mean 1.18
Standard deviation 0.65
Values 0.75 0.57 1.4 2
[302]
ref_hepatocyte CYP2W1
Mean 0.591
Standard deviation 1.2
Values 0 0 0.16 2.8 0
[303]
HepG2 CYP2W1
Mean 16.9
Standard deviation 4.5
Values 20 14
[304]
HepG2.C3A CYP2W1
Mean 56.5
Standard deviation 39
Values 29 84
[305]
HuH.7 CYP2W1
Mean 0.798
Standard deviation 0.23
Values 0.65 1.1 0.68
[306]
SNU475 CYP2W1
Mean 0.101
Standard deviation 0.028
Values 0.081 0.12
[307]
THLE CYP2W1
Mean 0.0849
Standard deviation 0.022
Values 0.1 0.069
[308]
liver CYP2W1
Mean 0.0517
Standard deviation 0.06
Values 0.093 0.11 0 0
[309]
ref_hepatocyte CYP2S1
Mean 0.536
Standard deviation 0.51
Values 1.4 0.61 0.1 0.27 0.31
[310]
HepG2 CYP2S1
Mean 8.91
Standard deviation 2.7
Values 7 11
[311]
HepG2.C3A CYP2S1
Mean 3.61
Standard deviation 0.85
Values 3 4.2
[312]
HuH.7 CYP2S1
Mean 1.97
Standard deviation 1.2
Values 2.2 0.73 3
[313]
SNU475 CYP2S1
Mean 2.23
Standard deviation 1.5
Values 3.3 1.2
[314]
THLE CYP2S1
Mean 2.64
Standard deviation 0.9
Values 2 3.3
[315]
liver CYP2S1
Mean 0.486
Standard deviation 0.16
Values 0.45 0.4 0.38 0.72
[316]
ref_hepatocyte CYP24A1
Mean 0.344
Standard deviation 0.69
Values 0 0 0 1.6 0.15
[317]
HepG2 CYP24A1
Mean 215
Standard deviation 90
Values 1.5e+02 2.8e+02
[318]
HepG2.C3A CYP24A1
Mean 6.56
Standard deviation 2.9
Values 8.6 4.5
[319]
HuH.7 CYP24A1
Mean 0.126
Standard deviation 0.11
Values 0.019 0.24 0.11
[320]
SNU475 CYP24A1
Mean 10.9
Standard deviation 10
Values 18 3.8
[321]
THLE CYP24A1
Mean 0.109
Standard deviation 0.079
Values 0.053 0.16
[322]
liver CYP24A1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[323]
ref_hepatocyte CYP4X1
Mean 0.333
Standard deviation 0.41
Values 0 0.79 0.78 0 0.1
[324]
HepG2 CYP4X1
Mean 0.0107
Standard deviation 0.015
Values 0.021 0
[325]
HepG2.C3A CYP4X1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[326]
HuH.7 CYP4X1
Mean 0
Standard deviation 0
Values 0 0 0
[327]
SNU475 CYP4X1
Mean 0.0175
Standard deviation 0.018
Values 0.03 0.0046
[328]
THLE CYP4X1
Mean 0.0452
Standard deviation 0.011
Values 0.053 0.037
[329]
liver CYP4X1
Mean 1.72
Standard deviation 0.26
Values 1.9 1.9 1.3 1.8
[330]
ref_hepatocyte CYP26A1
Mean 0.247
Standard deviation 0.38
Values 0 0.37 0.86 0 0
[331]
HepG2 CYP26A1
Mean 4.9
Standard deviation 3.4
Values 2.5 7.3
[332]
HepG2.C3A CYP26A1
Mean 0.0764
Standard deviation 0.0019
Values 0.075 0.078
[333]
HuH.7 CYP26A1
Mean 0.853
Standard deviation 0.36
Values 0.76 1.3 0.55
[334]
SNU475 CYP26A1
Mean 0.504
Standard deviation 0.37
Values 0.24 0.77
[335]
THLE CYP26A1
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[336]
liver CYP26A1
Mean 0.705
Standard deviation 0.82
Values 0.04 0.74 0.19 1.8
[337]
ref_hepatocyte CYP17A1
Mean 0.208
Standard deviation 0.25
Values 0.31 0.13 0.6 0 0
[338]
HepG2 CYP17A1
Mean 0.0687
Standard deviation 0.024
Values 0.051 0.086
[339]
HepG2.C3A CYP17A1
Mean 1.01
Standard deviation 0.19
Values 0.88 1.1
[340]
HuH.7 CYP17A1
Mean 0.0898
Standard deviation 0.047
Values 0.094 0.13 0.041
[341]
SNU475 CYP17A1
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[342]
THLE CYP17A1
Mean 0.00828
Standard deviation 0.0033
Values 0.0059 0.011
[343]
liver CYP17A1
Mean 0.926
Standard deviation 1.4
Values 0.5 0.057 2.9 0.21
[344]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0.057 0.28 0 0
[345]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[346]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[347]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[348]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[349]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[350]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0.04 0.13 0 0.1
[351]
ref_hepatocyte CYP27C1
Mean 0.0643
Standard deviation 0.067
Values 0.011 0.18 0.026 0.056 0.049
[352]
HepG2 CYP27C1
Mean 0.0973
Standard deviation 0.057
Values 0.14 0.057
[353]
HepG2.C3A CYP27C1
Mean 0.142
Standard deviation 0.033
Values 0.12 0.17
[354]
HuH.7 CYP27C1
Mean 0.128
Standard deviation 0.072
Values 0.21 0.064 0.11
[355]
SNU475 CYP27C1
Mean 0.228
Standard deviation 0.093
Values 0.29 0.16
[356]
THLE CYP27C1
Mean 0.0946
Standard deviation 0.059
Values 0.14 0.053
[357]
liver CYP27C1
Mean 0.158
Standard deviation 0.092
Values 0.2 0.17 0.24 0.026
[358]
ref_hepatocyte CYP27B1
Mean 0.0505
Standard deviation 0.082
Values 0.19 0.065 0 0 0
[359]
HepG2 CYP27B1
Mean 0.715
Standard deviation 0.14
Values 0.81 0.62
[360]
HepG2.C3A CYP27B1
Mean 1.72
Standard deviation 0.25
Values 1.5 1.9
[361]
HuH.7 CYP27B1
Mean 1.08
Standard deviation 0.18
Values 1.3 0.89 1.1
[362]
SNU475 CYP27B1
Mean 0.211
Standard deviation 0.1
Values 0.28 0.14
[363]
THLE CYP27B1
Mean 0.395
Standard deviation 0.14
Values 0.5 0.29
[364]
liver CYP27B1
Mean 0.228
Standard deviation 0.17
Values 0.24 0.14 0.071 0.46
[365]
ref_hepatocyte CYP46A1
Mean 0.0447
Standard deviation 0.068
Values 0 0.15 0.069 0 0
[366]
HepG2 CYP46A1
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[367]
HepG2.C3A CYP46A1
Mean 0.0161
Standard deviation 0.023
Values 0.032 0
[368]
HuH.7 CYP46A1
Mean 0.00761
Standard deviation 0.0083
Values 0 0.0064 0.016
[369]
SNU475 CYP46A1
Mean 0.0139
Standard deviation 0.02
Values 0 0.028
[370]
THLE CYP46A1
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[371]
liver CYP46A1
Mean 0.303
Standard deviation 0.093
Values 0.3 0.17 0.38 0.36
[372]
ref_hepatocyte CYP2F1
Mean 0.026
Standard deviation 0.058
Values 0 0.13 0 0 0
[373]
HepG2 CYP2F1
Mean 0.0336
Standard deviation 0.007
Values 0.039 0.029
[374]
HepG2.C3A CYP2F1
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[375]
HuH.7 CYP2F1
Mean 0.185
Standard deviation 0.058
Values 0.14 0.25 0.16
[376]
SNU475 CYP2F1
Mean 0.129
Standard deviation 0.047
Values 0.096 0.16
[377]
THLE CYP2F1
Mean 0.0674
Standard deviation 0.0051
Values 0.071 0.064
[378]
liver CYP2F1
Mean 0.0726
Standard deviation 0.035
Values 0.093 0.071 0.024 0.1
[379]
ref_hepatocyte CYP4Z1
Mean 0.0179
Standard deviation 0.04
Values 0 0.089 0 0 0
[380]
HepG2 CYP4Z1
Mean 0
Standard deviation 0
Values 0 0
[381]
HepG2.C3A CYP4Z1
Mean 0
Standard deviation 0
Values 0 0
[382]
HuH.7 CYP4Z1
Mean 0
Standard deviation 0
Values 0 0 0
[383]
SNU475 CYP4Z1
Mean 0
Standard deviation 0
Values 0 0
[384]
THLE CYP4Z1
Mean 0
Standard deviation 0
Values 0 0
[385]
liver CYP4Z1
Mean 0.115
Standard deviation 0.038
Values 0.16 0.13 0.071 0.1
[386]
ref_hepatocyte CYP26B1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0.06 0 0
[387]
HepG2 CYP26B1
Mean 0.791
Standard deviation 0.35
Values 0.54 1
[388]
HepG2.C3A CYP26B1
Mean 0.0848
Standard deviation 0.092
Values 0.15 0.019
[389]
HuH.7 CYP26B1
Mean 12
Standard deviation 3.7
Values 14 7.7 14
[390]
SNU475 CYP26B1
Mean 2.31
Standard deviation 2.1
Values 3.8 0.84
[391]
THLE CYP26B1
Mean 1.52
Standard deviation 0.59
Values 1.9 1.1
[392]
liver CYP26B1
Mean 0.794
Standard deviation 0.48
Values 1.5 0.43 0.78 0.49
[393]
ref_hepatocyte CYP4F8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[394]
HepG2 CYP4F8
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[395]
HepG2.C3A CYP4F8
Mean 0
Standard deviation 0
Values 0 0
[396]
HuH.7 CYP4F8
Mean 0.00312
Standard deviation 0.0054
Values 0.0094 0 0
[397]
SNU475 CYP4F8
Mean 0.00253
Standard deviation 0.0036
Values 0.0051 0
[398]
THLE CYP4F8
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[399]
liver CYP4F8
Mean 0
Standard deviation 0
Values 0 0 0 0
[400]
ref_hepatocyte CYP2G1P
Missing
[401]
HepG2 CYP2G1P
Mean 0
Standard deviation 0
Values 0 0
[402]
HepG2.C3A CYP2G1P
Mean 0
Standard deviation 0
Values 0 0
[403]
HuH.7 CYP2G1P
Mean 0.0724
Standard deviation 0.072
Values 0.047 0.15 0.016
[404]
SNU475 CYP2G1P
Mean 0.0342
Standard deviation 0.009
Values 0.041 0.028
[405]
THLE CYP2G1P
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[406]
liver CYP2G1P
Mean 0.0683
Standard deviation 0.07
Values 0.053 0.17 0.024 0.026
[407]
ref_hepatocyte CYP26C1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[408]
HepG2 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[409]
HepG2.C3A CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[410]
HuH.7 CYP26C1
Mean 0.176
Standard deviation 0.084
Values 0.094 0.17 0.26
[411]
SNU475 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[412]
THLE CYP26C1
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[413]
liver CYP26C1
Mean 0.0165
Standard deviation 0.033
Values 0.066 0 0 0
[414]
ref_hepatocyte CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[415]
HepG2 CYP11B1
Mean 0.00287
Standard deviation 0.0041
Values 0 0.0057
[416]
HepG2.C3A CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[417]
HuH.7 CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0
[418]
SNU475 CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[419]
THLE CYP11B1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[420]
liver CYP11B1
Mean 0.00331
Standard deviation 0.0066
Values 0.013 0 0 0
[421]
ref_hepatocyte CYP11B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[422]
HepG2 CYP11B2
Missing
[423]
HepG2.C3A CYP11B2
Missing
[424]
HuH.7 CYP11B2
Missing
[425]
SNU475 CYP11B2
Missing
[426]
THLE CYP11B2
Missing
[427]
liver CYP11B2
Missing
[428]
ref_hepatocyte CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[429]
HepG2 CYP4B1
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[430]
HepG2.C3A CYP4B1
Mean 0
Standard deviation 0
Values 0 0
[431]
HuH.7 CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0
[432]
SNU475 CYP4B1
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[433]
THLE CYP4B1
Mean 0.129
Standard deviation 0.077
Values 0.18 0.074
[434]
liver CYP4B1
Mean 0.0575
Standard deviation 0.045
Values 0.11 0 0.047 0.077
[435]
ref_hepatocyte MIR4651
Missing
[436]
HepG2 MIR4651
Mean 0.00214
Standard deviation 0.003
Values 0.0043 0
[437]
HepG2.C3A MIR4651
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[438]
HuH.7 MIR4651
Mean 0
Standard deviation 0
Values 0 0 0
[439]
SNU475 MIR4651
Mean 0
Standard deviation 0
Values 0 0
[440]
THLE MIR4651
Mean 0
Standard deviation 0
Values 0 0
[441]
liver MIR4651
Mean 0
Standard deviation 0
Values 0 0 0 0