WP_OVERVIEW_OF_PROINFLAMMATORY_AND_PROFIBROTIC_MEDIATORS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | CCL20 | C-C motif chemokine 20 | [1] | -2.50[2] | 0.13[3] | 0.02[4] | -8.08[5] | -4.30[6] | -8.86[7] |
2 | CXCL2 | C-X-C motif chemokine 2 | [8] | -7.20[9] | -7.91[10] | -4.98[11] | -6.25[12] | -2.58[13] | 1.57[14] |
3 | SPP1 | Osteopontin | [15] | 3.46[16] | 2.06[17] | -4.85[18] | 2.98[19] | -5.62[20] | 0.09[21] |
4 | IL1RN | Interleukin-1 receptor antagonist protein | [22] | -3.36[23] | -0.79[24] | -7.38[25] | [26] | -8.18[27] | 0.58[28] |
5 | CCL16 | C-C motif chemokine 16 | [29] | -5.20[30] | -2.78[31] | -7.76[32] | -9.59[33] | -9.35[34] | -0.67[35] |
6 | CXCL1 | Growth-regulated alpha protein | [36] | -6.16[37] | -10.14[38] | -3.63[39] | -4.82[40] | 1.42[41] | -4.33[42] |
7 | VEGFA | Vascular endothelial growth factor A | [43] | 1.50[44] | 2.67[45] | 2.86[46] | 1.52[47] | 1.70[48] | 1.95[49] |
8 | CCL15 | C-C motif chemokine 15 | [50] | -6.47[51] | -6.28[52] | -6.43[53] | -12.44[54] | [55] | -2.84[56] |
9 | CCL3L1 | C-C motif chemokine 3-like 1 | [57] | [58] | [59] | [60] | [61] | [62] | [63] |
10 | IL18 | Interleukin-18 | [64] | -0.58[65] | -4.58[66] | 1.14[67] | -0.09[68] | -1.28[69] | -2.99[70] |
11 | CCL14 | C-C motif chemokine 14 | [71] | [72] | [73] | [74] | [75] | [76] | -4.35[77] |
12 | CCL2 | C-C motif chemokine 2 | [78] | -13.11[79] | [80] | -11.11[81] | -3.03[82] | -1.40[83] | -2.52[84] |
13 | MMP1 | Interstitial collagenase | [85] | -4.88[86] | -8.82[87] | [88] | -0.67[89] | -1.65[90] | -10.96[91] |
14 | MMP3 | Stromelysin-1 | [92] | -4.23[93] | -9.32[94] | -10.09[95] | -0.66[96] | -4.25[97] | -7.15[98] |
15 | CXCL16 | C-X-C motif chemokine 16 | [99] | 0.73[100] | 1.66[101] | 2.02[102] | -0.96[103] | -2.57[104] | 1.18[105] |
16 | CXCL5 | C-X-C motif chemokine 5 | [106] | -3.65[107] | -7.49[108] | 2.58[109] | -2.88[110] | 3.17[111] | -7.01[112] |
17 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [113] | 0.95[114] | 0.46[115] | 1.84[116] | 0.84[117] | 1.21[118] | 1.62[119] |
18 | CCL3 | C-C motif chemokine 3 | [120] | [121] | [122] | [123] | -7.11[124] | [125] | -3.25[126] |
19 | CCL4 | C-C motif chemokine 4 | [127] | [128] | [129] | [130] | [131] | [132] | -2.24[133] |
20 | CX3CL1 | Fractalkine | [134] | 2.11[135] | 2.56[136] | 1.02[137] | -5.80[138] | -8.99[139] | -0.33[140] |
21 | AREG | Amphiregulin | [141] | -2.58[142] | -5.99[143] | -6.15[144] | -8.61[145] | 1.16[146] | -9.14[147] |
22 | CSF1 | Macrophage colony-stimulating factor 1 | [148] | 1.33[149] | -3.55[150] | 2.22[151] | 4.08[152] | 3.02[153] | 1.58[154] |
23 | EPO | Erythropoietin | [155] | -0.85[156] | 1.14[157] | -1.11[158] | -8.59[159] | -11.00[160] | 1.16[161] |
24 | CXCL13 | C-X-C motif chemokine 13 | [162] | -10.40[163] | [164] | -10.17[165] | [166] | [167] | -1.36[168] |
25 | CCL5 | C-C motif chemokine 5 | [169] | -4.48[170] | -4.10[171] | -2.35[172] | -2.62[173] | -4.34[174] | 1.90[175] |
26 | CXCL3 | C-X-C motif chemokine 3 | [176] | -4.54[177] | -6.98[178] | -2.11[179] | -3.38[180] | -0.45[181] | -4.44[182] |
27 | TSLP | Thymic stromal lymphopoietin | [183] | -8.15[184] | [185] | -7.96[186] | -4.74[187] | -2.10[188] | -1.50[189] |
28 | IL1B | Interleukin-1 beta | [190] | -8.41[191] | -8.45[192] | -2.53[193] | -2.51[194] | 2.55[195] | -4.03[196] |
29 | TNFSF13 | Tumor necrosis factor ligand superfamily member 13 | [197] | -1.64[198] | -1.71[199] | -3.13[200] | -2.16[201] | -1.12[202] | -0.98[203] |
30 | TGFB1 | Transforming growth factor beta-1 | [204] | 3.76[205] | 2.55[206] | 1.39[207] | 4.92[208] | 3.62[209] | -0.06[210] |
31 | CXCL6 | C-X-C motif chemokine 6 | [211] | -9.12[212] | [213] | -3.95[214] | -3.06[215] | 2.68[216] | 0.07[217] |
32 | IL27 | Interleukin-27 subunit alpha | [218] | -5.56[219] | -4.09[220] | 0.39[221] | [222] | -9.86[223] | -0.52[224] |
33 | CSF3 | Granulocyte colony-stimulating factor | [225] | -1.89[226] | -5.67[227] | -4.48[228] | -5.86[229] | 5.01[230] | -6.25[231] |
34 | LIF | Leukemia inhibitory factor | [232] | 2.57[233] | 2.23[234] | 4.66[235] | 2.70[236] | 3.19[237] | -4.01[238] |
35 | IL15 | Interleukin-15 | [239] | -1.72[240] | -1.75[241] | 1.90[242] | -1.08[243] | 0.05[244] | 0.28[245] |
36 | CXCL10 | C-X-C motif chemokine 10 | [246] | -8.86[247] | -6.72[248] | -0.01[249] | -0.47[250] | -8.60[251] | -1.21[252] |
37 | EBI3 | Interleukin-27 subunit beta | [253] | -0.55[254] | -0.01[255] | -1.23[256] | 0.76[257] | -3.84[258] | 0.12[259] |
38 | IL6 | Interleukin-6 | [260] | -8.16[261] | [262] | -3.13[263] | 0.23[264] | 2.21[265] | [266] |
39 | IL23A | Interleukin-23 subunit alpha | [267] | -1.86[268] | -1.92[269] | -2.08[270] | -3.85[271] | -3.31[272] | -2.62[273] |
40 | IL7 | Interleukin-7 | [274] | -2.37[275] | -1.07[276] | -5.09[277] | -4.72[278] | -1.62[279] | 2.47[280] |
41 | IL24 | Interleukin-24 | [281] | [282] | [283] | -8.20[284] | -0.92[285] | 0.41[286] | -5.40[287] |
42 | CCL4L2 | [288] | [289] | [290] | [291] | [292] | [293] | [294] | |
43 | CXCL12 | Stromal cell-derived factor 1 | [295] | -6.30[296] | -5.92[297] | -3.78[298] | 4.57[299] | 5.72[300] | 5.70[301] |
44 | MMP9 | Matrix metalloproteinase-9 | [302] | -2.43[303] | -3.65[304] | -4.46[305] | -0.35[306] | -3.44[307] | 1.03[308] |
45 | CCL28 | C-C motif chemokine 28 | [309] | -4.49[310] | -4.27[311] | -2.82[312] | 0.43[313] | -0.35[314] | -0.30[315] |
46 | CCL18 | C-C motif chemokine 18 | [316] | [317] | [318] | -7.17[319] | [320] | [321] | -1.64[322] |
47 | IL10 | Interleukin-10 | [323] | -1.59[324] | -2.01[325] | -0.24[326] | -0.90[327] | -1.90[328] | -0.42[329] |
48 | XCL2 | Cytokine SCM-1 beta | [330] | -8.64[331] | [332] | -3.48[333] | -3.14[334] | [335] | -1.98[336] |
49 | IL33 | Interleukin-33 | [337] | -2.65[338] | -7.39[339] | 1.94[340] | -2.10[341] | 6.46[342] | 5.83[343] |
50 | IL36G | Interleukin-36 gamma | [344] | -7.14[345] | -7.38[346] | -2.60[347] | [348] | -5.16[349] | -4.14[350] |
51 | CCL3L3 | [351] | [352] | [353] | [354] | [355] | [356] | [357] | |
52 | CXCL11 | C-X-C motif chemokine 11 | [358] | -8.00[359] | -5.56[360] | -3.80[361] | -1.46[362] | -4.80[363] | -1.67[364] |
53 | CCL26 | C-C motif chemokine 26 | [365] | 0.00[366] | -4.57[367] | [368] | 2.25[369] | -2.55[370] | -3.40[371] |
54 | TNFSF13B | Tumor necrosis factor ligand superfamily member 13B | [372] | -5.61[373] | -2.80[374] | -2.33[375] | 0.01[376] | 0.94[377] | 4.00[378] |
55 | IL19 | Interleukin-19 | [379] | [380] | [381] | -5.96[382] | -5.66[383] | [384] | -2.63[385] |
56 | IL37 | Interleukin-37 | [386] | -4.99[387] | -2.73[388] | -3.84[389] | -6.75[390] | -2.56[391] | [392] |
57 | CXCL9 | C-X-C motif chemokine 9 | [393] | -7.40[394] | [395] | -2.58[396] | -0.89[397] | [398] | 1.56[399] |
58 | CCL22 | C-C motif chemokine 22 | [400] | -1.09[401] | -1.10[402] | -0.85[403] | -1.08[404] | -1.67[405] | -1.51[406] |
59 | PPBP | Platelet basic protein | [407] | [408] | [409] | [410] | [411] | -3.03[412] | 1.65[413] |
60 | CCL23 | C-C motif chemokine 23 | [414] | -3.09[415] | -3.22[416] | -5.03[417] | [418] | [419] | 3.91[420] |
61 | IL17D | Interleukin-17D | [421] | 0.04[422] | 1.31[423] | 1.09[424] | 0.49[425] | -1.34[426] | -1.19[427] |
62 | IFNG | Interferon gamma | [428] | [429] | [430] | [431] | 0.39[432] | [433] | -1.13[434] |
63 | CTF1 | Cardiotrophin-1 | [435] | 1.98[436] | 1.52[437] | 0.54[438] | -2.76[439] | 1.75[440] | -1.20[441] |
64 | XCL1 | Lymphotactin | [442] | 0.72[443] | 1.99[444] | 3.34[445] | 2.12[446] | -4.83[447] | 0.05[448] |
65 | CCL27 | C-C motif chemokine 27 | [449] | -5.09[450] | -4.29[451] | -2.66[452] | -5.79[453] | -4.73[454] | -1.96[455] |
66 | IL12A | Interleukin-12 subunit alpha | [456] | -1.12[457] | [458] | 1.80[459] | -0.46[460] | 0.81[461] | -2.00[462] |
67 | IL17B | Interleukin-17B | [463] | -0.44[464] | 3.89[465] | -2.52[466] | 1.39[467] | -4.16[468] | -3.17[469] |
68 | PF4 | Platelet factor 4 | [470] | [471] | [472] | [473] | -1.41[474] | 1.64[475] | 0.72[476] |
69 | TNF | Tumor necrosis factor | [477] | 1.38[478] | -0.92[479] | -3.92[480] | -1.14[481] | -4.89[482] | -0.72[483] |
70 | IFNK | Interferon kappa | [484] | [485] | [486] | [487] | [488] | [489] | 1.08[490] |
71 | CCL7 | C-C motif chemokine 7 | [491] | [492] | [493] | [494] | -1.62[495] | -1.87[496] | [497] |
72 | CCL21 | C-C motif chemokine 21 | [498] | [499] | [500] | [501] | [502] | [503] | 5.67[504] |
73 | OSM | Oncostatin-M | [505] | -5.01[506] | -0.62[507] | -3.78[508] | -4.12[509] | -4.60[510] | -0.56[511] |
74 | IL11 | Interleukin-11 | [512] | 6.77[513] | 2.97[514] | 2.05[515] | 4.26[516] | 3.66[517] | -0.47[518] |
75 | CCL24 | C-C motif chemokine 24 | [519] | -5.95[520] | [521] | [522] | -4.06[523] | -4.69[524] | -0.18[525] |
76 | CCL8 | C-C motif chemokine 8 | [526] | [527] | [528] | [529] | -1.01[530] | [531] | [532] |
77 | IL36A | Interleukin-36 alpha | [533] | [534] | [535] | [536] | [537] | [538] | [539] |
78 | CCL17 | C-C motif chemokine 17 | [540] | [541] | -3.21[542] | -1.19[543] | [544] | [545] | -1.91[546] |
79 | IL20 | Interleukin-20 | [547] | [548] | [549] | [550] | [551] | -2.00[552] | -2.75[553] |
80 | IL1A | Interleukin-1 alpha | [554] | -0.14[555] | -0.71[556] | -0.30[557] | 0.44[558] | 6.66[559] | -0.41[560] |
81 | LTA | Lymphotoxin-alpha | [561] | -3.09[562] | [563] | -1.24[564] | 0.23[565] | -2.56[566] | -0.67[567] |
82 | IL36RN | Interleukin-36 receptor antagonist protein | [568] | [569] | [570] | [571] | -2.92[572] | -4.48[573] | [574] |
83 | CSF2 | Granulocyte-macrophage colony-stimulating factor | [575] | 0.75[576] | -3.37[577] | -1.14[578] | -0.63[579] | 6.73[580] | -0.30[581] |
84 | CNTF | Ciliary neurotrophic factor | [582] | [583] | -1.17[584] | -1.62[585] | -0.01[586] | -2.63[587] | 1.89[588] |
85 | PF4V1 | Platelet factor 4 variant | [589] | [590] | [591] | [592] | -0.99[593] | -0.33[594] | 2.59[595] |
86 | CXCL14 | C-X-C motif chemokine 14 | [596] | 1.36[597] | 2.31[598] | 2.40[599] | 4.73[600] | 3.29[601] | 8.86[602] |
87 | IL17A | Interleukin-17A | [603] | [604] | [605] | [606] | [607] | [608] | [609] |
88 | IL26 | Interleukin-26 | [610] | [611] | [612] | [613] | -0.25[614] | [615] | -1.63[616] |
89 | CCL19 | C-C motif chemokine 19 | [617] | [618] | -1.56[619] | [620] | [621] | [622] | 4.08[623] |
90 | IFNA1 | Interferon alpha-1/13 | [624] | [625] | [626] | [627] | [628] | [629] | [630] |
91 | IL12B | Interleukin-12 subunit beta | [631] | [632] | [633] | [634] | [635] | [636] | [637] |
92 | IFNL3 | Interferon lambda-3 | [638] | [639] | [640] | [641] | [642] | [643] | [644] |
93 | IFNA7 | Interferon alpha-7 | [645] | [646] | [647] | [648] | [649] | [650] | [651] |
94 | IFNA16 | Interferon alpha-16 | [652] | [653] | [654] | [655] | [656] | [657] | [658] |
95 | CCL11 | Eotaxin | [659] | [660] | [661] | [662] | [663] | [664] | [665] |
96 | CCL13 | C-C motif chemokine 13 | [666] | [667] | [668] | [669] | [670] | [671] | [672] |
97 | IFNA17 | Interferon alpha-17 | [673] | [674] | [675] | [676] | [677] | [678] | [679] |
98 | IFNA10 | Interferon alpha-10 | [680] | [681] | [682] | [683] | [684] | [685] | [686] |
99 | IFNA5 | Interferon alpha-5 | [687] | [688] | [689] | [690] | [691] | [692] | [693] |
100 | IL17F | Interleukin-17F | [694] | [695] | [696] | [697] | [698] | [699] | [700] |
101 | IFNL1 | Interferon lambda-1 | [701] | [702] | [703] | [704] | [705] | [706] | [707] |
102 | IFNA13 | [708] | [709] | [710] | [711] | [712] | [713] | [714] | |
103 | IL21 | Interleukin-21 | [715] | [716] | [717] | [718] | [719] | [720] | [721] |
104 | IL25 | Interleukin-25 | [722] | [723] | [724] | [725] | [726] | [727] | [728] |
105 | CXCL17 | C-X-C motif chemokine 17 | [729] | [730] | [731] | [732] | [733] | [734] | [735] |
106 | IL2 | Interleukin-2 | [736] | [737] | [738] | [739] | [740] | [741] | [742] |
107 | IL22 | Interleukin-22 | [743] | [744] | [745] | [746] | [747] | [748] | [749] |
108 | IL9 | Interleukin-9 | [750] | [751] | [752] | [753] | [754] | [755] | [756] |
109 | CCL1 | C-C motif chemokine 1 | [757] | [758] | [759] | [760] | [761] | [762] | [763] |
110 | CCL25 | C-C motif chemokine 25 | [764] | [765] | [766] | [767] | [768] | [769] | [770] |
111 | IFNA2 | Interferon alpha-2 | [771] | [772] | [773] | [774] | [775] | [776] | [777] |
112 | IL5 | Interleukin-5 | [778] | [779] | [780] | [781] | [782] | [783] | [784] |
113 | IL17C | Interleukin-17C | [785] | [786] | [787] | [788] | [789] | [790] | [791] |
114 | IFNA6 | Interferon alpha-6 | [792] | [793] | [794] | [795] | [796] | [797] | [798] |
115 | IL3 | Interleukin-3 | [799] | [800] | [801] | [802] | [803] | [804] | [805] |
116 | IFNA21 | Interferon alpha-21 | [806] | [807] | [808] | [809] | [810] | [811] | [812] |
117 | IFNW1 | Interferon omega-1 | [813] | [814] | [815] | [816] | [817] | [818] | [819] |
118 | IL31 | Interleukin-31 | [820] | [821] | [822] | [823] | [824] | [825] | [826] |
119 | IFNB1 | Interferon beta | [827] | [828] | [829] | [830] | [831] | [832] | [833] |
120 | IL36B | Interleukin-36 beta | [834] | [835] | [836] | [837] | [838] | [839] | [840] |
121 | CXCL8 | Interleukin-8 | [841] | [842] | [843] | [844] | [845] | [846] | [847] |
122 | IL4 | Interleukin-4 | [848] | [849] | [850] | [851] | [852] | [853] | [854] |
123 | IFNA14 | Interferon alpha-14 | [855] | [856] | [857] | [858] | [859] | [860] | [861] |
124 | IFNA4 | Interferon alpha-4 | [862] | [863] | [864] | [865] | [866] | [867] | [868] |
125 | IL1F10 | Interleukin-1 family member 10 | [869] | [870] | [871] | [872] | [873] | [874] | [875] |
126 | IL13 | Interleukin-13 | [876] | [877] | [878] | [879] | [880] | [881] | [882] |
127 | IFNA8 | Interferon alpha-8 | [883] | [884] | [885] | [886] | [887] | [888] | [889] |
128 | IFNL2 | Interferon lambda-2 | [890] | [891] | [892] | [893] | [894] | [895] | [896] |