WP_OVERVIEW_OF_NANOPARTICLE_EFFECTS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CRP C-reactive protein [1] [2] [3] -15.42[4] [5] -15.67[6] -0.21[7]
2 FN1 Fibronectin [8] 4.46[9] 4.45[10] 4.48[11] 4.31[12] 4.38[13] 2.06[14]
3 HMOX1 Heme oxygenase 1 [15] 0.49[16] 0.07[17] -0.91[18] -0.20[19] -0.57[20] -2.32[21]
4 BAX Apoptosis regulator BAX [22] 1.30[23] 1.02[24] 0.69[25] -0.21[26] 0.04[27] -4.19[28]
5 PTK2 Focal adhesion kinase 1 [29] 1.71[30] 2.70[31] 3.22[32] 3.34[33] 2.41[34] 0.52[35]
6 CCND3 G1/S-specific cyclin-D3 [36] 1.92[37] 1.37[38] -0.12[39] 5.06[40] 4.10[41] 0.42[42]
7 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2.86[43] 4.46[44] 0.78[45] 1.67[46] 2.31[47] 0.06[48]
8 NFRKB Nuclear factor related to kappa-B-binding protein [49] 3.85[50] 4.22[51] 4.30[52] 3.87[53] 3.33[54] 2.07[55]
9 IL6 Interleukin-6 [56] -7.47[57] [58] -3.22[59] 0.54[60] 2.92[61] [62]
10 LAMA3 Laminin subunit alpha-3 [63] 4.50[64] 4.85[65] 0.95[66] 5.88[67] 3.05[68] 1.29[69]
11 AKT3 RAC-gamma serine/threonine-protein kinase [70] -0.87[71] -2.92[72] -2.10[73] 7.24[74] 6.06[75] 3.37[76]
12 COL4A1 Collagen alpha-1(IV) chain [77] -1.76[78] -2.24[79] -0.75[80] 8.78[81] 8.42[82] 5.83[83]
13 CDH3 Cadherin-3 [84] -0.41[85] -2.22[86] -2.52[87] -0.90[88] -1.20[89] -2.95[90]
14 ITGAD Integrin alpha-D [91] -4.21[92] [93] [94] -3.52[95] [96] 3.23[97]
15 PTGS1 Prostaglandin G/H synthase 1 [98] 2.32[99] -4.08[100] -2.21[101] 4.08[102] 6.77[103] 2.74[104]
16 TNF Tumor necrosis factor [105] 2.07[106] 0.45[107] -4.02[108] -0.83[109] -4.18[110] -2.13[111]
17 BCL2 Apoptosis regulator Bcl-2 [112] -1.88[113] 4.03[114] -3.24[115] 3.17[116] 2.75[117] 3.00[118]
18 PTGS2 Prostaglandin G/H synthase 2 [119] [120] -1.14[121] -0.75[122] 4.26[123] 9.94[124] 2.60[125]
19 CXCL8 Interleukin-8 [126] [127] [128] [129] [130] [131] [132]
[1]
ref_hepatocyte CRP
Mean 3.33e+03
Standard deviation 5.7e+03
Values 7.6e+02 2.4e+03 1.3e+04 0 4.8
[2]
HepG2 CRP
Mean 0
Standard deviation 0
Values 0 0
[3]
HepG2.C3A CRP
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 CRP
Mean 0.0466
Standard deviation 0.01
Values 0.037 0.045 0.057
[5]
SNU475 CRP
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE CRP
Mean 0.0547
Standard deviation 0.04
Values 0.083 0.027
[7]
liver CRP
Mean 4.8e+03
Standard deviation 4.3e+03
Values 1.6e+03 3.6e+03 2.9e+03 1.1e+04
[8]
ref_hepatocyte FN1
Mean 152
Standard deviation 1.4e+02
Values 27 3.8e+02 1.7e+02 1.3e+02 57
[9]
HepG2 FN1
Mean 3.78e+03
Standard deviation 3.9e+02
Values 3.5e+03 4.1e+03
[10]
HepG2.C3A FN1
Mean 2.34e+03
Standard deviation 1.3e+03
Values 1.4e+03 3.2e+03
[11]
HuH.7 FN1
Mean 2.08e+03
Standard deviation 9.6e+02
Values 1.3e+03 3.1e+03 1.8e+03
[12]
SNU475 FN1
Mean 2.11e+03
Standard deviation 1.4e+02
Values 2.2e+03 2e+03
[13]
THLE FN1
Mean 2.73e+03
Standard deviation 1.5e+03
Values 1.7e+03 3.8e+03
[14]
liver FN1
Mean 1.06e+03
Standard deviation 3.8e+02
Values 1.4e+03 1.3e+03 5.9e+02 9.3e+02
[15]
ref_hepatocyte HMOX1
Mean 45.4
Standard deviation 44
Values 1.2e+02 37 47 19 4.5
[16]
HepG2 HMOX1
Mean 71.8
Standard deviation 29
Values 52 92
[17]
HepG2.C3A HMOX1
Mean 33.6
Standard deviation 4.7
Values 37 30
[18]
HuH.7 HMOX1
Mean 14.9
Standard deviation 6.3
Values 12 22 10
[19]
SNU475 HMOX1
Mean 27.6
Standard deviation 4.6
Values 31 24
[20]
THLE HMOX1
Mean 26.2
Standard deviation 9.7
Values 19 33
[21]
liver HMOX1
Mean 15.2
Standard deviation 2.1
Values 15 13 16 18
[22]
ref_hepatocyte BAX
Mean 24.8
Standard deviation 9.1
Values 34 11 27 30 21
[23]
HepG2 BAX
Mean 68.8
Standard deviation 16
Values 58 80
[24]
HepG2.C3A BAX
Mean 35.4
Standard deviation 3
Values 33 38
[25]
HuH.7 BAX
Mean 24.6
Standard deviation 9.8
Values 34 14 26
[26]
SNU475 BAX
Mean 15
Standard deviation 0.87
Values 16 14
[27]
THLE BAX
Mean 21.9
Standard deviation 0.028
Values 22 22
[28]
liver BAX
Mean 2.27
Standard deviation 0.64
Values 1.4 2.5 2.3 2.9
[29]
ref_hepatocyte PTK2
Mean 8.92
Standard deviation 4.8
Values 11 3.9 4.1 15 11
[30]
HepG2 PTK2
Mean 32.8
Standard deviation 5.2
Values 36 29
[31]
HepG2.C3A PTK2
Mean 40.9
Standard deviation 2.3
Values 39 43
[32]
HuH.7 PTK2
Mean 51.1
Standard deviation 2.8
Values 48 52 53
[33]
SNU475 PTK2
Mean 63.1
Standard deviation 3.5
Values 61 66
[34]
THLE PTK2
Mean 40.6
Standard deviation 3.7
Values 38 43
[35]
liver PTK2
Mean 21.5
Standard deviation 4.9
Values 24 27 19 16
[36]
ref_hepatocyte CCND3
Mean 3.59
Standard deviation 2.1
Values 3.5 3.9 6.6 0.75 3.2
[37]
HepG2 CCND3
Mean 15.4
Standard deviation 1
Values 16 15
[38]
HepG2.C3A CCND3
Mean 6.55
Standard deviation 2.7
Values 8.4 4.7
[39]
HuH.7 CCND3
Mean 2.03
Standard deviation 0.8
Values 2.6 1.1 2.3
[40]
SNU475 CCND3
Mean 83.7
Standard deviation 2.9
Values 86 82
[41]
THLE CCND3
Mean 52.9
Standard deviation 6.7
Values 48 58
[42]
liver CCND3
Mean 8.04
Standard deviation 5
Values 4.1 3.8 10 14
[43]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 3.3 0.66 0.38 4.1 0.94
[44]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 13 18
[45]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 27 31
[46]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 1.6 2.3 2
[47]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 3.7 4.6
[48]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[49]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 5.1 3 2.4 2.6
[50]
ref_hepatocyte NFRKB
Mean 1.5
Standard deviation 0.32
Values 1.3 1.3 1.6 2 1.2
[51]
HepG2 NFRKB
Mean 24.3
Standard deviation 0.19
Values 24 24
[52]
HepG2.C3A NFRKB
Mean 19.7
Standard deviation 2.8
Values 18 22
[53]
HuH.7 NFRKB
Mean 18.2
Standard deviation 0.27
Values 18 18 18
[54]
SNU475 NFRKB
Mean 15.2
Standard deviation 0.87
Values 15 16
[55]
THLE NFRKB
Mean 12.9
Standard deviation 0.21
Values 13 13
[56]
liver NFRKB
Mean 10.5
Standard deviation 0.81
Values 11 10 11 9.7
[57]
ref_hepatocyte IL6
Mean 1.35
Standard deviation 2.5
Values 5.9 0.28 0.6 0 0
[58]
HepG2 IL6
Mean 0.0086
Standard deviation 0.012
Values 0 0.017
[59]
HepG2.C3A IL6
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 IL6
Mean 0.0895
Standard deviation 0.012
Values 0.1 0.083 0.082
[61]
SNU475 IL6
Mean 1.37
Standard deviation 1.7
Values 2.6 0.15
[62]
THLE IL6
Mean 8.81
Standard deviation 1.5
Values 7.7 9.9
[63]
liver IL6
Mean 0
Standard deviation 0
Values 0 0 0 0
[64]
ref_hepatocyte LAMA3
Mean 0.394
Standard deviation 0.27
Values 0.29 0.27 0.35 0.19 0.87
[65]
HepG2 LAMA3
Mean 10
Standard deviation 3.2
Values 7.7 12
[66]
HepG2.C3A LAMA3
Mean 7.99
Standard deviation 3.7
Values 11 5.4
[67]
HuH.7 LAMA3
Mean 0.467
Standard deviation 0.18
Values 0.28 0.64 0.48
[68]
SNU475 LAMA3
Mean 16.2
Standard deviation 10
Values 8.8 24
[69]
THLE LAMA3
Mean 2.8
Standard deviation 0.21
Values 2.7 2.9
[70]
liver LAMA3
Mean 1.61
Standard deviation 1.2
Values 2.9 2.4 0.66 0.49
[71]
ref_hepatocyte AKT3
Mean 0.387
Standard deviation 0.32
Values 0.83 0.41 0.16 0 0.53
[72]
HepG2 AKT3
Mean 0.238
Standard deviation 0.15
Values 0.13 0.34
[73]
HepG2.C3A AKT3
Mean 0.036
Standard deviation 0.0097
Values 0.043 0.029
[74]
HuH.7 AKT3
Mean 0.0557
Standard deviation 0.031
Values 0.028 0.09 0.049
[75]
SNU475 AKT3
Mean 40.8
Standard deviation 10
Values 34 48
[76]
THLE AKT3
Mean 22.1
Standard deviation 4.4
Values 25 19
[77]
liver AKT3
Mean 6.71
Standard deviation 4.9
Values 9.4 12 2.8 2.3
[78]
ref_hepatocyte COL4A1
Mean 0.353
Standard deviation 0.31
Values 0.76 0.46 0.43 0 0.11
[79]
HepG2 COL4A1
Mean 0.117
Standard deviation 0.069
Values 0.069 0.17
[80]
HepG2.C3A COL4A1
Mean 0.0526
Standard deviation 0.047
Values 0.086 0.019
[81]
HuH.7 COL4A1
Mean 0.129
Standard deviation 0.08
Values 0.037 0.16 0.19
[82]
SNU475 COL4A1
Mean 108
Standard deviation 58
Values 67 1.5e+02
[83]
THLE COL4A1
Mean 104
Standard deviation 59
Values 62 1.5e+02
[84]
liver COL4A1
Mean 33.7
Standard deviation 21
Values 36 58 8.2 32
[85]
ref_hepatocyte CDH3
Mean 0.292
Standard deviation 0.51
Values 1.2 0.22 0 0 0.06
[86]
HepG2 CDH3
Mean 0.247
Standard deviation 0.14
Values 0.15 0.34
[87]
HepG2.C3A CDH3
Mean 0.0442
Standard deviation 0.047
Values 0.011 0.078
[88]
HuH.7 CDH3
Mean 0.0314
Standard deviation 0.025
Values 0.028 0.058 0.0082
[89]
SNU475 CDH3
Mean 0.109
Standard deviation 0.062
Values 0.066 0.15
[90]
THLE CDH3
Mean 0.109
Standard deviation 0.0037
Values 0.11 0.11
[91]
liver CDH3
Mean 0.0631
Standard deviation 0.046
Values 0.093 0.057 0 0.1
[92]
ref_hepatocyte ITGAD
Mean 0.118
Standard deviation 0.17
Values 0 0.37 0.22 0 0
[93]
HepG2 ITGAD
Mean 0.00716
Standard deviation 0.002
Values 0.0086 0.0057
[94]
HepG2.C3A ITGAD
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 ITGAD
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 ITGAD
Mean 0.00717
Standard deviation 0.003
Values 0.0051 0.0093
[97]
THLE ITGAD
Mean 0
Standard deviation 0
Values 0 0
[98]
liver ITGAD
Mean 1.85
Standard deviation 1.7
Values 2.6 3.8 0.071 0.9
[99]
ref_hepatocyte PTGS1
Mean 0.117
Standard deviation 0.16
Values 0.13 0.39 0.06 0 0
[100]
HepG2 PTGS1
Mean 0.657
Standard deviation 0.75
Values 0.13 1.2
[101]
HepG2.C3A PTGS1
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[102]
HuH.7 PTGS1
Mean 0.0156
Standard deviation 0.02
Values 0 0.039 0.0082
[103]
SNU475 PTGS1
Mean 1.38
Standard deviation 0.25
Values 1.2 1.5
[104]
THLE PTGS1
Mean 11
Standard deviation 1.1
Values 10 12
[105]
liver PTGS1
Mean 1.31
Standard deviation 0.36
Values 0.78 1.5 1.4 1.6
[106]
ref_hepatocyte TNF
Mean 0.113
Standard deviation 0.17
Values 0 0.39 0.17 0 0
[107]
HepG2 TNF
Mean 0.533
Standard deviation 0.44
Values 0.22 0.84
[108]
HepG2.C3A TNF
Mean 0.108
Standard deviation 0.029
Values 0.13 0.087
[109]
HuH.7 TNF
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[110]
SNU475 TNF
Mean 0.0443
Standard deviation 0.023
Values 0.061 0.028
[111]
THLE TNF
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[112]
liver TNF
Mean 0.0431
Standard deviation 0.06
Values 0.13 0.014 0 0.026
[113]
ref_hepatocyte BCL2
Mean 0.0984
Standard deviation 0.087
Values 0.15 0.2 0.12 0.019 0
[114]
HepG2 BCL2
Mean 0.0301
Standard deviation 0.0061
Values 0.026 0.034
[115]
HepG2.C3A BCL2
Mean 1.13
Standard deviation 0.21
Values 0.99 1.3
[116]
HuH.7 BCL2
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[117]
SNU475 BCL2
Mean 0.618
Standard deviation 0.094
Values 0.68 0.55
[118]
THLE BCL2
Mean 0.568
Standard deviation 0.0088
Values 0.56 0.57
[119]
liver BCL2
Mean 1.31
Standard deviation 1
Values 2.5 1.8 0.49 0.49
[120]
ref_hepatocyte PTGS2
Mean 0.032
Standard deviation 0.045
Values 0 0.065 0.095 0 0
[121]
HepG2 PTGS2
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A PTGS2
Mean 0.0102
Standard deviation 0.00071
Values 0.011 0.0097
[123]
HuH.7 PTGS2
Mean 0.0117
Standard deviation 0.013
Values 0.0094 0.026 0
[124]
SNU475 PTGS2
Mean 0.428
Standard deviation 0.51
Values 0.79 0.07
[125]
THLE PTGS2
Mean 27
Standard deviation 7.8
Values 33 22
[126]
liver PTGS2
Mean 0.325
Standard deviation 0.24
Values 0.26 0.67 0.24 0.13
[127]
ref_hepatocyte CXCL8
Missing
[128]
HepG2 CXCL8
Missing
[129]
HepG2.C3A CXCL8
Missing
[130]
HuH.7 CXCL8
Missing
[131]
SNU475 CXCL8
Missing
[132]
THLE CXCL8
Missing
[133]
liver CXCL8
Missing