WP_OVERVIEW_OF_INTERFERONSMEDIATED_SIGNALING_PATHWAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | IFNGR1 | Interferon gamma receptor 1 | [1] | 0.49[2] | -0.49[3] | -1.76[4] | -1.34[5] | -1.08[6] | -1.54[7] |
2 | STAT1 | Signal transducer and activator of transcription 1-alpha/beta | [8] | -0.36[9] | -1.15[10] | 0.15[11] | 1.57[12] | -0.19[13] | -0.27[14] |
3 | IFNGR2 | Interferon gamma receptor 2 | [15] | -0.32[16] | 0.37[17] | -1.46[18] | -2.33[19] | -0.53[20] | -1.81[21] |
4 | JAK1 | Tyrosine-protein kinase JAK1 | [22] | 0.23[23] | -0.16[24] | 0.22[25] | -0.33[26] | 0.82[27] | 0.31[28] |
5 | IRF9 | Interferon regulatory factor 9 | [29] | -1.10[30] | -2.79[31] | -2.33[32] | -1.33[33] | -1.86[34] | -1.32[35] |
6 | IFNAR2 | Interferon alpha/beta receptor 2 | [36] | -1.50[37] | -1.71[38] | -0.83[39] | -2.35[40] | -1.85[41] | -2.00[42] |
7 | IL10RB | Interleukin-10 receptor subunit beta | [43] | -0.82[44] | -0.88[45] | -1.70[46] | -1.17[47] | -0.54[48] | -1.20[49] |
8 | IFNAR1 | Interferon alpha/beta receptor 1 | [50] | -0.22[51] | 0.38[52] | 0.28[53] | 0.03[54] | 0.52[55] | 1.21[56] |
9 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [57] | -0.76[58] | -0.51[59] | 0.78[60] | 1.11[61] | 1.12[62] | 1.78[63] |
10 | STAT2 | Signal transducer and activator of transcription 2 | [64] | -0.26[65] | 1.24[66] | 0.59[67] | 0.57[68] | 0.53[69] | 1.80[70] |
11 | TYK2 | Non-receptor tyrosine-protein kinase TYK2 | [71] | 0.85[72] | 1.34[73] | 1.67[74] | -0.21[75] | 1.22[76] | 0.76[77] |
12 | PRKCA | Protein kinase C alpha type | [78] | 2.55[79] | 2.72[80] | 3.28[81] | 1.19[82] | 2.06[83] | 0.69[84] |
13 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | -0.67[85] | 1.10[86] | 1.48[87] | 0.17[88] | 0.88[89] | 0.69[90] | |
14 | JAK2 | Tyrosine-protein kinase JAK2 | [91] | -0.06[92] | 0.07[93] | -0.18[94] | -0.20[95] | 0.91[96] | 1.48[97] |
15 | IFNG | Interferon gamma | [98] | [99] | [100] | [101] | -1.65[102] | [103] | -3.52[104] |
16 | IFNK | Interferon kappa | [105] | [106] | [107] | [108] | [109] | [110] | -1.32[111] |
17 | IFNA5 | Interferon alpha-5 | [112] | [113] | [114] | [115] | [116] | [117] | [118] |
18 | IFNA10 | Interferon alpha-10 | [119] | [120] | [121] | [122] | [123] | [124] | [125] |
19 | IFNA17 | Interferon alpha-17 | [126] | [127] | [128] | [129] | [130] | [131] | [132] |
20 | IFNA13 | [133] | [134] | [135] | [136] | [137] | [138] | [139] | |
21 | IFNL1 | Interferon lambda-1 | [140] | [141] | [142] | [143] | [144] | [145] | [146] |
22 | IFNA1 | Interferon alpha-1/13 | [147] | [148] | [149] | [150] | [151] | [152] | [153] |
23 | IFNL3 | Interferon lambda-3 | [154] | [155] | [156] | [157] | [158] | [159] | [160] |
24 | IFNA16 | Interferon alpha-16 | [161] | [162] | [163] | [164] | [165] | [166] | [167] |
25 | IFNA7 | Interferon alpha-7 | [168] | [169] | [170] | [171] | [172] | [173] | [174] |
26 | IFNE | Interferon epsilon | [175] | [176] | [177] | [178] | [179] | [180] | [181] |
27 | IFNLR1 | Interferon lambda receptor 1 | [182] | [183] | [184] | [185] | [186] | [187] | [188] |
28 | IFNA4 | Interferon alpha-4 | [189] | [190] | [191] | [192] | [193] | [194] | [195] |
29 | IFNA14 | Interferon alpha-14 | [196] | [197] | [198] | [199] | [200] | [201] | [202] |
30 | IFNL2 | Interferon lambda-2 | [203] | [204] | [205] | [206] | [207] | [208] | [209] |
31 | IFNA8 | Interferon alpha-8 | [210] | [211] | [212] | [213] | [214] | [215] | [216] |
32 | IFNL4 | Interferon lambda-4 | [217] | [218] | [219] | [220] | [221] | [222] | [223] |
33 | IFNA2 | Interferon alpha-2 | [224] | [225] | [226] | [227] | [228] | [229] | [230] |
34 | IFNW1 | Interferon omega-1 | [231] | [232] | [233] | [234] | [235] | [236] | [237] |
35 | IFNA21 | Interferon alpha-21 | [238] | [239] | [240] | [241] | [242] | [243] | [244] |
36 | IFNA6 | Interferon alpha-6 | [245] | [246] | [247] | [248] | [249] | [250] | [251] |
37 | IFNB1 | Interferon beta | [252] | [253] | [254] | [255] | [256] | [257] | [258] |