WP_ONECARBON_METABOLISM_AND_RELATED_PATHWAYS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SOD2 Superoxide dismutase [Mn], mitochondrial [1] -2.99[2] -2.54[3] -3.11[4] -3.41[5] -1.21[6] -2.36[7]
2 SOD1 Superoxide dismutase [Cu-Zn] [8] -1.47[9] -1.69[10] -2.43[11] -1.11[12] -1.17[13] -1.05[14]
3 GPX2 Glutathione peroxidase 2 [15] 1.08[16] 0.20[17] -1.70[18] -8.57[19] -8.66[20] -0.08[21]
4 GPX4 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial [22] 0.13[23] 0.31[24] 0.26[25] -0.07[26] -0.39[27] -1.32[28]
5 MAT1A S-adenosylmethionine synthase isoform type-1 [29] -1.58[30] 0.10[31] -1.58[32] -7.85[33] -10.28[34] 1.41[35]
6 GPX1 Glutathione peroxidase 1 [36] 0.41[37] -0.12[38] 0.50[39] 0.31[40] 1.37[41] -1.07[42]
7 BHMT Betaine--homocysteine S-methyltransferase 1 [43] -4.24[44] -4.62[45] -8.25[46] -6.95[47] -13.64[48] -0.34[49]
8 GPX3 Glutathione peroxidase 3 [50] 2.24[51] 0.61[52] 0.82[53] -0.45[54] -5.04[55] 1.56[56]
9 SHMT1 Serine hydroxymethyltransferase, cytosolic [57] -1.06[58] -1.34[59] -0.62[60] -0.25[61] -0.44[62] 1.65[63]
10 GNMT Glycine N-methyltransferase [64] -5.48[65] -4.24[66] -8.89[67] -6.72[68] -9.48[69] -0.72[70]
11 SHMT2 Serine hydroxymethyltransferase, mitochondrial [71] 1.81[72] 2.69[73] 2.46[74] 0.93[75] 2.29[76] 0.34[77]
12 CDO1 Cysteine dioxygenase type 1 [78] -4.32[79] -6.08[80] -3.86[81] -5.74[82] -10.94[83] 0.34[84]
13 BHMT2 S-methylmethionine--homocysteine S-methyltransferase BHMT2 [85] -1.41[86] -0.88[87] -0.03[88] 1.42[89] -6.16[90] 1.61[91]
14 CHPT1 Cholinephosphotransferase 1 [92] 0.87[93] 1.49[94] 0.59[95] -1.05[96] -0.12[97] -1.02[98]
15 BAAT Bile acid-CoA:amino acid N-acyltransferase [99] -3.58[100] -3.18[101] -5.27[102] -5.67[103] -6.89[104] 2.22[105]
16 PEMT Phosphatidylethanolamine N-methyltransferase [106] -0.98[107] -0.38[108] -1.88[109] -0.86[110] -1.53[111] 0.49[112]
17 GSR Glutathione reductase, mitochondrial [113] 2.46[114] 1.86[115] 2.58[116] 3.38[117] 1.89[118] -0.39[119]
18 ETNK2 Ethanolamine kinase 2 [120] -0.27[121] -0.58[122] -0.27[123] -1.53[124] -1.34[125] 0.76[126]
19 PCYT2 Ethanolamine-phosphate cytidylyltransferase [127] 2.15[128] 3.04[129] 2.23[130] 0.65[131] -0.22[132] 1.00[133]
20 TYMS Thymidylate synthase [134] 0.66[135] 0.87[136] 0.95[137] 1.28[138] 1.43[139] -5.46[140]
21 GCLC Glutamate--cysteine ligase catalytic subunit [141] 1.58[142] 1.73[143] 0.76[144] 3.54[145] 0.91[146] 0.89[147]
22 AGXT2 Alanine--glyoxylate aminotransferase 2, mitochondrial [148] -7.73[149] -8.85[150] 0.66[151] -8.04[152] -9.39[153] 0.68[154]
23 MAT2A S-adenosylmethionine synthase isoform type-2 [155] 2.45[156] 2.57[157] 2.62[158] 3.41[159] 3.73[160] 1.35[161]
24 AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 [162] 2.17[163] 2.06[164] 2.88[165] 3.60[166] 3.56[167] 0.77[168]
25 GCLM Glutamate--cysteine ligase regulatory subunit [169] 0.96[170] -0.02[171] 0.70[172] 3.43[173] 1.70[174] -0.37[175]
26 CTH Cystathionine gamma-lyase [176] -0.49[177] -1.45[178] 0.69[179] -2.01[180] -1.42[181] 0.41[182]
27 GSS Glutathione synthetase [183] 2.64[184] 2.13[185] 1.73[186] 2.92[187] 2.40[188] 0.23[189]
28 DMGDH Dimethylglycine dehydrogenase, mitochondrial [190] -1.46[191] -1.67[192] -0.25[193] 0.19[194] -6.22[195] 1.62[196]
29 PCYT1A Choline-phosphate cytidylyltransferase A [197] 0.45[198] 0.32[199] 0.59[200] 1.25[201] 1.37[202] -0.90[203]
30 SARDH Sarcosine dehydrogenase, mitochondrial [204] 1.13[205] 1.32[206] 1.36[207] -3.10[208] -1.32[209] 2.44[210]
31 CEPT1 Choline/ethanolaminephosphotransferase 1 [211] 1.10[212] 1.50[213] 1.26[214] 1.24[215] 1.82[216] 0.03[217]
32 CHDH Choline dehydrogenase, mitochondrial [218] 2.78[219] 3.54[220] 1.92[221] -3.42[222] -3.64[223] 1.96[224]
33 CSAD Cysteine sulfinic acid decarboxylase [225] -0.76[226] 0.80[227] 0.20[228] 0.73[229] 0.45[230] 1.11[231]
34 CHKA Choline kinase alpha [232] 3.61[233] 3.34[234] 4.29[235] 3.50[236] 1.74[237] 0.48[238]
35 ETNK1 Ethanolamine kinase 1 [239] 1.32[240] 3.13[241] 4.68[242] 2.35[243] 2.80[244] 3.04[245]
36 CHKB Choline/ethanolamine kinase [246] -4.01[247] -2.90[248] -2.86[249] -2.69[250] -4.37[251] -3.14[252]
37 BCAT2 Branched-chain-amino-acid aminotransferase, mitochondrial [253] -0.76[254] 0.00[255] 3.33[256] 3.51[257] 3.01[258] 0.70[259]
38 DNMT3A DNA (cytosine-5)-methyltransferase 3A [260] 3.45[261] 3.56[262] 3.71[263] 2.62[264] 2.11[265] 0.99[266]
39 PLD1 Phospholipase D1 [267] 4.35[268] 4.86[269] 5.60[270] 3.63[271] 4.32[272] 2.53[273]
40 GPX7 Glutathione peroxidase 7 [274] 1.52[275] 2.17[276] 2.30[277] -1.08[278] 1.21[279] 0.00[280]
41 MTR Methionine synthase [281] 4.20[282] 4.68[283] 5.08[284] 5.74[285] 5.16[286] 3.83[287]
42 BCAT1 Branched-chain-amino-acid aminotransferase, cytosolic [288] 5.39[289] 4.93[290] 7.56[291] 6.81[292] 8.32[293] 0.52[294]
43 MTHFR Methylenetetrahydrofolate reductase [295] 3.27[296] 4.42[297] 4.92[298] 5.29[299] 4.15[300] 4.28[301]
44 PCYT1B Choline-phosphate cytidylyltransferase B [302] 6.12[303] 4.91[304] 0.47[305] -0.12[306] 2.58[307] -0.98[308]
45 DNM1 Dynamin-1 [309] 4.17[310] 2.14[311] 4.09[312] 8.18[313] 7.76[314] 2.41[315]
46 GAD1 Glutamate decarboxylase 1 [316] 2.75[317] 2.86[318] 6.47[319] 1.32[320] 2.58[321] -3.32[322]
47 SOD3 Extracellular superoxide dismutase [Cu-Zn] [323] -1.24[324] -0.57[325] [326] 4.88[327] 1.41[328] 4.87[329]
48 GAD2 Glutamate decarboxylase 2 [330] [331] [332] [333] [334] [335] [336]
49 CBSL Cystathionine beta-synthase-like protein [337] [338] [339] [340] [341] [342] [343]
50 MIR6778 [344] [345] [346] [347] [348] [349] [350]
51 GPX5 Epididymal secretory glutathione peroxidase [351] [352] [353] [354] [355] [356] [357]
52 GPX6 Glutathione peroxidase 6 [358] [359] [360] [361] [362] [363] [364]
53 SOD2-OT1 [365] [366] [367] [368] [369] [370] [371]
54 DHFR2 Dihydrofolate reductase 2, mitochondrial [372] [373] [374] [375] [376] [377] [378]
[1]
ref_hepatocyte SOD2
Mean 955
Standard deviation 9.9e+02
Values 2.2e+03 2.7e+02 4e+02 59 1.9e+03
[2]
HepG2 SOD2
Mean 69.3
Standard deviation 2.2
Values 71 68
[3]
HepG2.C3A SOD2
Mean 97.8
Standard deviation 3.8
Values 95 1e+02
[4]
HuH.7 SOD2
Mean 53.1
Standard deviation 23
Values 36 79 44
[5]
SNU475 SOD2
Mean 27.5
Standard deviation 11
Values 35 20
[6]
THLE SOD2
Mean 133
Standard deviation 14
Values 1.2e+02 1.4e+02
[7]
liver SOD2
Mean 191
Standard deviation 1.1e+02
Values 2e+02 3.2e+02 56 1.9e+02
[8]
ref_hepatocyte SOD1
Mean 597
Standard deviation 4e+02
Values 1.7e+02 1.2e+03 7.2e+02 2.9e+02 6.1e+02
[9]
HepG2 SOD1
Mean 125
Standard deviation 15
Values 1.4e+02 1.1e+02
[10]
HepG2.C3A SOD1
Mean 110
Standard deviation 30
Values 1.3e+02 89
[11]
HuH.7 SOD1
Mean 53.3
Standard deviation 20
Values 71 31 57
[12]
SNU475 SOD1
Mean 84.9
Standard deviation 18
Values 72 97
[13]
THLE SOD1
Mean 85.3
Standard deviation 11
Values 78 93
[14]
liver SOD1
Mean 296
Standard deviation 2.4e+02
Values 63 1.1e+02 5.3e+02 4.8e+02
[15]
ref_hepatocyte GPX2
Mean 224
Standard deviation 2.7e+02
Values 19 4.5e+02 5.9e+02 61 9.6
[16]
HepG2 GPX2
Mean 274
Standard deviation 26
Values 2.6e+02 2.9e+02
[17]
HepG2.C3A GPX2
Mean 153
Standard deviation 85
Values 2.1e+02 93
[18]
HuH.7 GPX2
Mean 33.1
Standard deviation 7.7
Values 38 24 37
[19]
SNU475 GPX2
Mean 0.18
Standard deviation 0.025
Values 0.2 0.16
[20]
THLE GPX2
Mean 0.178
Standard deviation 0.026
Values 0.16 0.2
[21]
liver GPX2
Mean 218
Standard deviation 2.6e+02
Values 6.4 30 2.6e+02 5.7e+02
[22]
ref_hepatocyte GPX4
Mean 223
Standard deviation 63
Values 2.2e+02 2.5e+02 2e+02 3.1e+02 1.4e+02
[23]
HepG2 GPX4
Mean 141
Standard deviation 10
Values 1.3e+02 1.5e+02
[24]
HepG2.C3A GPX4
Mean 164
Standard deviation 3.3
Values 1.6e+02 1.7e+02
[25]
HuH.7 GPX4
Mean 128
Standard deviation 29
Values 1.6e+02 1.1e+02 1.1e+02
[26]
SNU475 GPX4
Mean 64.8
Standard deviation 11
Values 57 73
[27]
THLE GPX4
Mean 54.8
Standard deviation 1.7
Values 54 56
[28]
liver GPX4
Mean 91.2
Standard deviation 88
Values 12 18 1.7e+02 1.6e+02
[29]
ref_hepatocyte MAT1A
Mean 212
Standard deviation 2.8e+02
Values 7.2 6.3e+02 3.6e+02 46 12
[30]
HepG2 MAT1A
Mean 41.1
Standard deviation 3.9
Values 44 38
[31]
HepG2.C3A MAT1A
Mean 135
Standard deviation 10
Values 1.3e+02 1.4e+02
[32]
HuH.7 MAT1A
Mean 34.1
Standard deviation 22
Values 22 60 20
[33]
SNU475 MAT1A
Mean 0.281
Standard deviation 0.061
Values 0.24 0.32
[34]
THLE MAT1A
Mean 0.055
Standard deviation 0.048
Values 0.089 0.021
[35]
liver MAT1A
Mean 578
Standard deviation 1.7e+02
Values 4.1e+02 6.1e+02 4.8e+02 8.1e+02
[36]
ref_hepatocyte GPX1
Mean 167
Standard deviation 1e+02
Values 2.7e+02 1.8e+02 2.5e+02 30 1e+02
[37]
HepG2 GPX1
Mean 128
Standard deviation 3.5
Values 1.3e+02 1.3e+02
[38]
HepG2.C3A GPX1
Mean 91.1
Standard deviation 33
Values 1.1e+02 67
[39]
HuH.7 GPX1
Mean 113
Standard deviation 55
Values 1.6e+02 55 1.2e+02
[40]
SNU475 GPX1
Mean 63.3
Standard deviation 6.4
Values 59 68
[41]
THLE GPX1
Mean 139
Standard deviation 16
Values 1.3e+02 1.5e+02
[42]
liver GPX1
Mean 81.8
Standard deviation 69
Values 19 25 1.4e+02 1.4e+02
[43]
ref_hepatocyte BHMT
Mean 117
Standard deviation 1.9e+02
Values 6.9 4.5e+02 1.1e+02 8.1 4.9
[44]
HepG2 BHMT
Mean 3.57
Standard deviation 0.19
Values 3.4 3.7
[45]
HepG2.C3A BHMT
Mean 2.82
Standard deviation 2.3
Values 4.4 1.2
[46]
HuH.7 BHMT
Mean 0.184
Standard deviation 0.018
Values 0.2 0.19 0.16
[47]
SNU475 BHMT
Mean 0.29
Standard deviation 0.11
Values 0.21 0.37
[48]
THLE BHMT
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver BHMT
Mean 94.8
Standard deviation 50
Values 39 69 1.5e+02 1.2e+02
[50]
ref_hepatocyte GPX3
Mean 87.9
Standard deviation 1.1e+02
Values 47 76 2.8e+02 22 17
[51]
HepG2 GPX3
Mean 240
Standard deviation 69
Values 1.9e+02 2.9e+02
[52]
HepG2.C3A GPX3
Mean 79.8
Standard deviation 13
Values 71 89
[53]
HuH.7 GPX3
Mean 74.5
Standard deviation 41
Values 51 1.2e+02 51
[54]
SNU475 GPX3
Mean 19.7
Standard deviation 2.7
Values 22 18
[55]
THLE GPX3
Mean 0.86
Standard deviation 0.062
Values 0.82 0.9
[56]
liver GPX3
Mean 265
Standard deviation 2.9e+02
Values 35 1.2e+02 2.3e+02 6.8e+02
[57]
ref_hepatocyte SHMT1
Mean 76.7
Standard deviation 82
Values 18 1.6e+02 1.7e+02 15 16
[58]
HepG2 SHMT1
Mean 21.2
Standard deviation 4.7
Values 25 18
[59]
HepG2.C3A SHMT1
Mean 18
Standard deviation 5.4
Values 22 14
[60]
HuH.7 SHMT1
Mean 24
Standard deviation 7.5
Values 31 16 25
[61]
SNU475 SHMT1
Mean 19.7
Standard deviation 0.95
Values 19 20
[62]
THLE SHMT1
Mean 18.2
Standard deviation 3.2
Values 16 21
[63]
liver SHMT1
Mean 246
Standard deviation 1.2e+02
Values 1.3e+02 1.6e+02 3.3e+02 3.7e+02
[64]
ref_hepatocyte GNMT
Mean 73.6
Standard deviation 1.2e+02
Values 3.7 2.8e+02 81 2.1 0.55
[65]
HepG2 GNMT
Mean 0.952
Standard deviation 0.94
Values 1.6 0.29
[66]
HepG2.C3A GNMT
Mean 2.32
Standard deviation 0.99
Values 1.6 3
[67]
HuH.7 GNMT
Mean 0.0743
Standard deviation 0.035
Values 0.11 0.045 0.066
[68]
SNU475 GNMT
Mean 0.213
Standard deviation 0.079
Values 0.16 0.27
[69]
THLE GNMT
Mean 0.0331
Standard deviation 0.013
Values 0.024 0.043
[70]
liver GNMT
Mean 46
Standard deviation 29
Values 25 18 77 65
[71]
ref_hepatocyte SHMT2
Mean 66.5
Standard deviation 44
Values 61 78 1.4e+02 27 32
[72]
HepG2 SHMT2
Mean 135
Standard deviation 40
Values 1.1e+02 1.6e+02
[73]
HepG2.C3A SHMT2
Mean 256
Standard deviation 1e+02
Values 1.8e+02 3.3e+02
[74]
HuH.7 SHMT2
Mean 175
Standard deviation 6.4
Values 1.8e+02 1.8e+02 1.7e+02
[75]
SNU475 SHMT2
Mean 38.7
Standard deviation 3
Values 41 37
[76]
THLE SHMT2
Mean 105
Standard deviation 2.1
Values 1.1e+02 1e+02
[77]
liver SHMT2
Mean 86.4
Standard deviation 29
Values 59 67 1e+02 1.2e+02
[78]
ref_hepatocyte CDO1
Mean 64.7
Standard deviation 88
Values 1.9 1.9e+02 1.2e+02 1.9 6.3
[79]
HepG2 CDO1
Mean 1.88
Standard deviation 1.5
Values 2.9 0.83
[80]
HepG2.C3A CDO1
Mean 0.569
Standard deviation 0.38
Values 0.84 0.3
[81]
HuH.7 CDO1
Mean 2.14
Standard deviation 0.25
Values 2 2.4 2
[82]
SNU475 CDO1
Mean 0.371
Standard deviation 0.24
Values 0.54 0.2
[83]
THLE CDO1
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[84]
liver CDO1
Mean 83.9
Standard deviation 21
Values 62 76 87 1.1e+02
[85]
ref_hepatocyte BHMT2
Mean 64.6
Standard deviation 65
Values 21 1.7e+02 89 9.2 37
[86]
HepG2 BHMT2
Mean 14.1
Standard deviation 2.5
Values 12 16
[87]
HepG2.C3A BHMT2
Mean 20.9
Standard deviation 1.5
Values 22 20
[88]
HuH.7 BHMT2
Mean 30.4
Standard deviation 1.6
Values 32 29 29
[89]
SNU475 BHMT2
Mean 53
Standard deviation 14
Values 43 63
[90]
THLE BHMT2
Mean 0.29
Standard deviation 0.05
Values 0.33 0.26
[91]
liver BHMT2
Mean 202
Standard deviation 88
Values 1.2e+02 1.3e+02 2.9e+02 2.7e+02
[92]
ref_hepatocyte CHPT1
Mean 51.9
Standard deviation 41
Values 9.9 50 47 1.2e+02 34
[93]
HepG2 CHPT1
Mean 54.8
Standard deviation 22
Values 70 39
[94]
HepG2.C3A CHPT1
Mean 86.8
Standard deviation 20
Values 1e+02 73
[95]
HuH.7 CHPT1
Mean 37.6
Standard deviation 2.3
Values 40 38 35
[96]
SNU475 CHPT1
Mean 7.64
Standard deviation 0.99
Values 6.9 8.3
[97]
THLE CHPT1
Mean 15.4
Standard deviation 1.6
Values 14 17
[98]
liver CHPT1
Mean 26.3
Standard deviation 11
Values 16 20 39 30
[99]
ref_hepatocyte BAAT
Mean 50.1
Standard deviation 39
Values 17 84 89 1.6 59
[100]
HepG2 BAAT
Mean 2.42
Standard deviation 0.81
Values 3 1.9
[101]
HepG2.C3A BAAT
Mean 3.29
Standard deviation 0.29
Values 3.1 3.5
[102]
HuH.7 BAAT
Mean 0.621
Standard deviation 0.84
Values 0.18 1.6 0.098
[103]
SNU475 BAAT
Mean 0.302
Standard deviation 0.27
Values 0.11 0.49
[104]
THLE BAAT
Mean 0.136
Standard deviation 0.042
Values 0.17 0.11
[105]
liver BAAT
Mean 239
Standard deviation 1.3e+02
Values 1.1e+02 1.7e+02 4.1e+02 2.7e+02
[106]
ref_hepatocyte PEMT
Mean 36.5
Standard deviation 41
Values 13 93 66 5.5 4.4
[107]
HepG2 PEMT
Mean 10.7
Standard deviation 1.2
Values 9.8 12
[108]
HepG2.C3A PEMT
Mean 16.7
Standard deviation 7.9
Values 11 22
[109]
HuH.7 PEMT
Mean 4.78
Standard deviation 0.99
Values 4.9 3.7 5.7
[110]
SNU475 PEMT
Mean 6.17
Standard deviation 0.66
Values 5.7 6.6
[111]
THLE PEMT
Mean 4.09
Standard deviation 0.51
Values 4.4 3.7
[112]
liver PEMT
Mean 52.7
Standard deviation 35
Values 28 17 82 84
[113]
ref_hepatocyte GSR
Mean 31.7
Standard deviation 20
Values 29 12 16 63 38
[114]
HepG2 GSR
Mean 101
Standard deviation 36
Values 75 1.3e+02
[115]
HepG2.C3A GSR
Mean 68.4
Standard deviation 11
Values 77 60
[116]
HuH.7 GSR
Mean 90.7
Standard deviation 6
Values 95 84 93
[117]
SNU475 GSR
Mean 101
Standard deviation 25
Values 83 1.2e+02
[118]
THLE GSR
Mean 37.8
Standard deviation 6.5
Values 33 42
[119]
liver GSR
Mean 24.8
Standard deviation 7.4
Values 32 30 16 21
[120]
ref_hepatocyte ETNK2
Mean 29.3
Standard deviation 27
Values 4.7 59 56 20 6.1
[121]
HepG2 ETNK2
Mean 14.1
Standard deviation 1.1
Values 13 15
[122]
HepG2.C3A ETNK2
Mean 11.7
Standard deviation 2.7
Values 9.7 14
[123]
HuH.7 ETNK2
Mean 11.7
Standard deviation 4.1
Values 8.6 16 10
[124]
SNU475 ETNK2
Mean 3.12
Standard deviation 0.18
Values 3 3.2
[125]
THLE ETNK2
Mean 3.73
Standard deviation 0.27
Values 3.9 3.5
[126]
liver ETNK2
Mean 51
Standard deviation 28
Values 44 26 91 43
[127]
ref_hepatocyte PCYT2
Mean 25.9
Standard deviation 14
Values 9.8 43 25 37 15
[128]
HepG2 PCYT2
Mean 66.4
Standard deviation 26
Values 85 48
[129]
HepG2.C3A PCYT2
Mean 127
Standard deviation 25
Values 1.1e+02 1.4e+02
[130]
HuH.7 PCYT2
Mean 58.3
Standard deviation 11
Values 67 46 62
[131]
SNU475 PCYT2
Mean 12.4
Standard deviation 6.9
Values 7.5 17
[132]
THLE PCYT2
Mean 7.19
Standard deviation 2
Values 5.8 8.6
[133]
liver PCYT2
Mean 53
Standard deviation 21
Values 44 29 78 61
[134]
ref_hepatocyte TYMS
Mean 24.8
Standard deviation 32
Values 2.5 0.91 3.3 69 49
[135]
HepG2 TYMS
Mean 22.7
Standard deviation 7.9
Values 28 17
[136]
HepG2.C3A TYMS
Mean 26.9
Standard deviation 18
Values 40 14
[137]
HuH.7 TYMS
Mean 23
Standard deviation 12
Values 32 9.1 28
[138]
SNU475 TYMS
Mean 18.5
Standard deviation 1.2
Values 19 18
[139]
THLE TYMS
Mean 21.5
Standard deviation 4.9
Values 18 25
[140]
liver TYMS
Mean 0.58
Standard deviation 0.68
Values 0 0.4 0.35 1.6
[141]
ref_hepatocyte GCLC
Mean 23.9
Standard deviation 11
Values 36 37 16 14 17
[142]
HepG2 GCLC
Mean 41.2
Standard deviation 0.21
Values 41 41
[143]
HepG2.C3A GCLC
Mean 47.1
Standard deviation 0.68
Values 47 48
[144]
HuH.7 GCLC
Mean 19.4
Standard deviation 7.4
Values 15 28 15
[145]
SNU475 GCLC
Mean 84.8
Standard deviation 9.1
Values 78 91
[146]
THLE GCLC
Mean 14.4
Standard deviation 0.55
Values 15 14
[147]
liver GCLC
Mean 45.3
Standard deviation 20
Values 64 59 37 22
[148]
ref_hepatocyte AGXT2
Mean 23.4
Standard deviation 33
Values 1.4 72 43 0 0.88
[149]
HepG2 AGXT2
Mean 0.0637
Standard deviation 0.05
Values 0.099 0.029
[150]
HepG2.C3A AGXT2
Mean 0.0302
Standard deviation 0.012
Values 0.021 0.039
[151]
HuH.7 AGXT2
Mean 17.8
Standard deviation 1.5
Values 19 18 16
[152]
SNU475 AGXT2
Mean 0.0272
Standard deviation 0.019
Values 0.041 0.014
[153]
THLE AGXT2
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[154]
liver AGXT2
Mean 38.5
Standard deviation 15
Values 25 25 50 54
[155]
ref_hepatocyte MAT2A
Mean 23.3
Standard deviation 13
Values 14 16 44 15 27
[156]
HepG2 MAT2A
Mean 73.6
Standard deviation 11
Values 81 66
[157]
HepG2.C3A MAT2A
Mean 82.6
Standard deviation 22
Values 98 67
[158]
HuH.7 MAT2A
Mean 68.8
Standard deviation 31
Values 93 34 79
[159]
SNU475 MAT2A
Mean 75.8
Standard deviation 6
Values 80 72
[160]
THLE MAT2A
Mean 99.7
Standard deviation 1.6
Values 1e+02 99
[161]
liver MAT2A
Mean 61
Standard deviation 25
Values 34 46 78 86
[162]
ref_hepatocyte AHCYL1
Mean 21.3
Standard deviation 7.5
Values 12 18 20 25 31
[163]
HepG2 AHCYL1
Mean 55.4
Standard deviation 1.1
Values 55 56
[164]
HepG2.C3A AHCYL1
Mean 52.7
Standard deviation 1.2
Values 52 54
[165]
HuH.7 AHCYL1
Mean 75.1
Standard deviation 17
Values 79 56 90
[166]
SNU475 AHCYL1
Mean 78.9
Standard deviation 16
Values 67 90
[167]
THLE AHCYL1
Mean 80.7
Standard deviation 6.3
Values 76 85
[168]
liver AHCYL1
Mean 37.2
Standard deviation 6
Values 30 41 43 35
[169]
ref_hepatocyte GCLM
Mean 20.7
Standard deviation 17
Values 32 5.2 8.4 12 45
[170]
HepG2 GCLM
Mean 23.3
Standard deviation 15
Values 13 34
[171]
HepG2.C3A GCLM
Mean 12.1
Standard deviation 3.1
Values 14 9.9
[172]
HuH.7 GCLM
Mean 16.1
Standard deviation 2.7
Values 13 19 16
[173]
SNU475 GCLM
Mean 68.3
Standard deviation 0.053
Values 68 68
[174]
THLE GCLM
Mean 21.6
Standard deviation 2.7
Values 20 24
[175]
liver GCLM
Mean 16.4
Standard deviation 8.1
Values 7 14 18 27
[176]
ref_hepatocyte CTH
Mean 20.3
Standard deviation 26
Values 9.9 64 24 1.2 1.6
[177]
HepG2 CTH
Mean 8.35
Standard deviation 5.8
Values 4.2 12
[178]
HepG2.C3A CTH
Mean 4.42
Standard deviation 2.6
Values 2.6 6.3
[179]
HuH.7 CTH
Mean 15.7
Standard deviation 1.2
Values 14 17 16
[180]
SNU475 CTH
Mean 1.54
Standard deviation 0.042
Values 1.6 1.5
[181]
THLE CTH
Mean 2.44
Standard deviation 0.065
Values 2.5 2.4
[182]
liver CTH
Mean 27.6
Standard deviation 15
Values 13 17 38 43
[183]
ref_hepatocyte GSS
Mean 17.2
Standard deviation 2.6
Values 20 17 20 14 16
[184]
HepG2 GSS
Mean 61.8
Standard deviation 7.1
Values 67 57
[185]
HepG2.C3A GSS
Mean 45
Standard deviation 7.3
Values 50 40
[186]
HuH.7 GSS
Mean 27.4
Standard deviation 7
Values 34 20 27
[187]
SNU475 GSS
Mean 39.8
Standard deviation 5.9
Values 36 44
[188]
THLE GSS
Mean 29.3
Standard deviation 2.5
Values 27 31
[189]
liver GSS
Mean 20.8
Standard deviation 9.9
Values 11 14 26 32
[190]
ref_hepatocyte DMGDH
Mean 16.7
Standard deviation 24
Values 0.82 58 19 2.9 2.5
[191]
HepG2 DMGDH
Mean 3.51
Standard deviation 0.46
Values 3.8 3.2
[192]
HepG2.C3A DMGDH
Mean 3.12
Standard deviation 0.38
Values 2.9 3.4
[193]
HuH.7 DMGDH
Mean 6.73
Standard deviation 2.1
Values 4.7 9 6.5
[194]
SNU475 DMGDH
Mean 5.82
Standard deviation 2.5
Values 4 7.6
[195]
THLE DMGDH
Mean 0.0722
Standard deviation 0.057
Values 0.11 0.032
[196]
liver DMGDH
Mean 52.7
Standard deviation 11
Values 62 62 40 47
[197]
ref_hepatocyte PCYT1A
Mean 15.9
Standard deviation 12
Values 32 5.9 6.6 9.8 25
[198]
HepG2 PCYT1A
Mean 12.5
Standard deviation 3.2
Values 15 10
[199]
HepG2.C3A PCYT1A
Mean 11.9
Standard deviation 3.3
Values 14 9.5
[200]
HuH.7 PCYT1A
Mean 11.5
Standard deviation 1.6
Values 10 11 13
[201]
SNU475 PCYT1A
Mean 11.6
Standard deviation 2.1
Values 10 13
[202]
THLE PCYT1A
Mean 13.3
Standard deviation 2.7
Values 11 15
[203]
liver PCYT1A
Mean 8.76
Standard deviation 2.6
Values 9.8 12 5.6 7.9
[204]
ref_hepatocyte SARDH
Mean 15.9
Standard deviation 20
Values 0.51 42 32 4.6 0.76
[205]
HepG2 SARDH
Mean 20.2
Standard deviation 1.3
Values 21 19
[206]
HepG2.C3A SARDH
Mean 23.7
Standard deviation 3.8
Values 21 26
[207]
HuH.7 SARDH
Mean 19.6
Standard deviation 4.3
Values 18 16 24
[208]
SNU475 SARDH
Mean 0.567
Standard deviation 0.057
Values 0.53 0.61
[209]
THLE SARDH
Mean 2.05
Standard deviation 0.015
Values 2.1 2
[210]
liver SARDH
Mean 88.9
Standard deviation 39
Values 1.5e+02 80 71 59
[211]
ref_hepatocyte CEPT1
Mean 12.6
Standard deviation 6.5
Values 5.6 10 9.1 22 16
[212]
HepG2 CEPT1
Mean 15.6
Standard deviation 0.37
Values 16 15
[213]
HepG2.C3A CEPT1
Mean 21.2
Standard deviation 1.2
Values 20 22
[214]
HuH.7 CEPT1
Mean 14.5
Standard deviation 1.6
Values 14 16 13
[215]
SNU475 CEPT1
Mean 9.15
Standard deviation 1.6
Values 8 10
[216]
THLE CEPT1
Mean 14.4
Standard deviation 0.63
Values 15 14
[217]
liver CEPT1
Mean 13.2
Standard deviation 2.2
Values 12 12 17 12
[218]
ref_hepatocyte CHDH
Mean 8.63
Standard deviation 5.4
Values 3.1 14 11 13 2.5
[219]
HepG2 CHDH
Mean 34.2
Standard deviation 8.2
Values 40 28
[220]
HepG2.C3A CHDH
Mean 59.6
Standard deviation 4.1
Values 57 63
[221]
HuH.7 CHDH
Mean 15.6
Standard deviation 0.26
Values 15 16 16
[222]
SNU475 CHDH
Mean 0.247
Standard deviation 0.005
Values 0.24 0.25
[223]
THLE CHDH
Mean 0.222
Standard deviation 0.1
Values 0.3 0.15
[224]
liver CHDH
Mean 34.4
Standard deviation 9.9
Values 21 44 34 39
[225]
ref_hepatocyte CSAD
Mean 7.55
Standard deviation 9.6
Values 0.95 22 12 1.3 0.97
[226]
HepG2 CSAD
Mean 2.57
Standard deviation 0.32
Values 2.8 2.3
[227]
HepG2.C3A CSAD
Mean 7.82
Standard deviation 2
Values 6.4 9.2
[228]
HuH.7 CSAD
Mean 4.16
Standard deviation 1.3
Values 5.5 3.9 3
[229]
SNU475 CSAD
Mean 3.82
Standard deviation 1.3
Values 2.9 4.7
[230]
THLE CSAD
Mean 3.32
Standard deviation 0.99
Values 4 2.6
[231]
liver CSAD
Mean 16.7
Standard deviation 6.4
Values 9.5 14 20 24
[232]
ref_hepatocyte CHKA
Mean 7.34
Standard deviation 5.6
Values 3.8 6.9 5 17 4
[233]
HepG2 CHKA
Mean 51.9
Standard deviation 3.7
Values 54 49
[234]
HepG2.C3A CHKA
Mean 44.3
Standard deviation 5.6
Values 40 48
[235]
HuH.7 CHKA
Mean 69.1
Standard deviation 18
Values 63 89 55
[236]
SNU475 CHKA
Mean 25.4
Standard deviation 0.82
Values 25 26
[237]
THLE CHKA
Mean 7.89
Standard deviation 0.21
Values 7.7 8
[238]
liver CHKA
Mean 10.5
Standard deviation 0.71
Values 10 11 11 9.6
[239]
ref_hepatocyte ETNK1
Mean 7.05
Standard deviation 2
Values 5 5.6 6.7 8 10
[240]
HepG2 ETNK1
Mean 10.1
Standard deviation 2.8
Values 12 8.2
[241]
HepG2.C3A ETNK1
Mean 36.7
Standard deviation 9.6
Values 30 43
[242]
HuH.7 ETNK1
Mean 86.7
Standard deviation 22
Values 74 1.1e+02 74
[243]
SNU475 ETNK1
Mean 11
Standard deviation 0.98
Values 10 12
[244]
THLE ETNK1
Mean 15.8
Standard deviation 1
Values 17 15
[245]
liver ETNK1
Mean 59.6
Standard deviation 17
Values 41 51 68 79
[246]
ref_hepatocyte CHKB
Mean 3.95
Standard deviation 2.4
Values 3.7 6.9 5.8 1.2 2.2
[247]
HepG2 CHKB
Mean 0.142
Standard deviation 0.018
Values 0.13 0.15
[248]
HepG2.C3A CHKB
Mean 0.316
Standard deviation 0.16
Values 0.2 0.43
[249]
HuH.7 CHKB
Mean 0.26
Standard deviation 0.065
Values 0.33 0.2 0.25
[250]
SNU475 CHKB
Mean 0.187
Standard deviation 0.064
Values 0.14 0.23
[251]
THLE CHKB
Mean 0.0615
Standard deviation 0.0033
Values 0.059 0.064
[252]
liver CHKB
Mean 0.459
Standard deviation 0.38
Values 0.15 0.19 0.96 0.54
[253]
ref_hepatocyte BCAT2
Mean 3.91
Standard deviation 2.4
Values 2.9 5 4.6 0.36 6.6
[254]
HepG2 BCAT2
Mean 1.33
Standard deviation 0.16
Values 1.2 1.4
[255]
HepG2.C3A BCAT2
Mean 2.32
Standard deviation 0.055
Values 2.3 2.4
[256]
HuH.7 BCAT2
Mean 18.9
Standard deviation 8.7
Values 24 8.8 23
[257]
SNU475 BCAT2
Mean 13.6
Standard deviation 2.8
Values 12 16
[258]
THLE BCAT2
Mean 10.2
Standard deviation 1.4
Values 9.2 11
[259]
liver BCAT2
Mean 6.53
Standard deviation 4.8
Values 3.2 2.3 13 7.9
[260]
ref_hepatocyte DNMT3A
Mean 2.8
Standard deviation 3.3
Values 1.1 1.3 1.2 8.7 1.7
[261]
HepG2 DNMT3A
Mean 17.7
Standard deviation 0.61
Values 17 18
[262]
HepG2.C3A DNMT3A
Mean 19.7
Standard deviation 0.75
Values 20 19
[263]
HuH.7 DNMT3A
Mean 17.6
Standard deviation 2.3
Values 16 16 20
[264]
SNU475 DNMT3A
Mean 5.28
Standard deviation 2.5
Values 3.5 7
[265]
THLE DNMT3A
Mean 3.91
Standard deviation 0.33
Values 3.7 4.1
[266]
liver DNMT3A
Mean 5.72
Standard deviation 1.9
Values 7.1 6.3 6.5 3
[267]
ref_hepatocyte PLD1
Mean 2.16
Standard deviation 1.3
Values 0.51 3.9 2.2 2.7 1.5
[268]
HepG2 PLD1
Mean 25.5
Standard deviation 3.1
Values 28 23
[269]
HepG2.C3A PLD1
Mean 37.3
Standard deviation 8.3
Values 31 43
[270]
HuH.7 PLD1
Mean 50.2
Standard deviation 9.4
Values 40 59 52
[271]
SNU475 PLD1
Mean 8.19
Standard deviation 1.4
Values 7.2 9.2
[272]
THLE PLD1
Mean 13.9
Standard deviation 1.2
Values 13 15
[273]
liver PLD1
Mean 12.8
Standard deviation 4.4
Values 17 15 12 7.2
[274]
ref_hepatocyte GPX7
Mean 1.92
Standard deviation 3
Values 0.82 0.54 0.82 7.2 0.19
[275]
HepG2 GPX7
Mean 3.18
Standard deviation 0.14
Values 3.1 3.3
[276]
HepG2.C3A GPX7
Mean 5.13
Standard deviation 0.33
Values 4.9 5.4
[277]
HuH.7 GPX7
Mean 4.54
Standard deviation 0.85
Values 5.4 4.5 3.7
[278]
SNU475 GPX7
Mean 0.278
Standard deviation 0.25
Values 0.1 0.45
[279]
THLE GPX7
Mean 1.43
Standard deviation 0.15
Values 1.5 1.3
[280]
liver GPX7
Mean 1.97
Standard deviation 0.54
Values 1.3 1.9 2.1 2.6
[281]
ref_hepatocyte MTR
Mean 1.43
Standard deviation 1
Values 1.2 0.48 0.53 2.9 2.1
[282]
HepG2 MTR
Mean 15.2
Standard deviation 4.2
Values 18 12
[283]
HepG2.C3A MTR
Mean 21.8
Standard deviation 0.68
Values 21 22
[284]
HuH.7 MTR
Mean 23.2
Standard deviation 4.8
Values 20 21 29
[285]
SNU475 MTR
Mean 23.4
Standard deviation 7.7
Values 18 29
[286]
THLE MTR
Mean 16.5
Standard deviation 1
Values 17 16
[287]
liver MTR
Mean 20.9
Standard deviation 9.9
Values 24 34 12 14
[288]
ref_hepatocyte BCAT1
Mean 1.1
Standard deviation 1.6
Values 0.91 0.46 0.078 4 0.11
[289]
HepG2 BCAT1
Mean 26.7
Standard deviation 1
Values 26 27
[290]
HepG2.C3A BCAT1
Mean 20
Standard deviation 6.4
Values 16 25
[291]
HuH.7 BCAT1
Mean 100
Standard deviation 19
Values 92 87 1.2e+02
[292]
SNU475 BCAT1
Mean 37.8
Standard deviation 14
Values 28 48
[293]
THLE BCAT1
Mean 114
Standard deviation 20
Values 1.3e+02 99
[294]
liver BCAT1
Mean 1.62
Standard deviation 0.82
Values 2.1 2.5 0.59 1.4
[295]
ref_hepatocyte MTHFR
Mean 0.857
Standard deviation 0.14
Values 0.91 0.6 0.95 0.9 0.92
[296]
HepG2 MTHFR
Mean 4.76
Standard deviation 0.36
Values 5 4.5
[297]
HepG2.C3A MTHFR
Mean 10.9
Standard deviation 2
Values 9.5 12
[298]
HuH.7 MTHFR
Mean 12.4
Standard deviation 3.7
Values 9.7 17 11
[299]
SNU475 MTHFR
Mean 10.2
Standard deviation 3.7
Values 7.6 13
[300]
THLE MTHFR
Mean 4.9
Standard deviation 0.19
Values 5 4.8
[301]
liver MTHFR
Mean 17.1
Standard deviation 4.4
Values 19 21 17 11
[302]
ref_hepatocyte PCYT1B
Mean 0.237
Standard deviation 0.31
Values 0.45 0.065 0 0.67 0
[303]
HepG2 PCYT1B
Mean 9.5
Standard deviation 8
Values 15 3.9
[304]
HepG2.C3A PCYT1B
Mean 4.24
Standard deviation 2
Values 5.6 2.8
[305]
HuH.7 PCYT1B
Mean 0.157
Standard deviation 0.084
Values 0.25 0.096 0.12
[306]
SNU475 PCYT1B
Mean 0.0667
Standard deviation 0.042
Values 0.096 0.037
[307]
THLE PCYT1B
Mean 0.456
Standard deviation 0.13
Values 0.54 0.37
[308]
liver PCYT1B
Mean 0.123
Standard deviation 0.088
Values 0.16 0.13 0 0.21
[309]
ref_hepatocyte DNM1
Mean 0.16
Standard deviation 0.16
Values 0 0.3 0.35 0 0.15
[310]
HepG2 DNM1
Mean 1.67
Standard deviation 1.2
Values 0.85 2.5
[311]
HepG2.C3A DNM1
Mean 0.418
Standard deviation 0.29
Values 0.21 0.62
[312]
HuH.7 DNM1
Mean 1.31
Standard deviation 0.22
Values 1.1 1.5 1.3
[313]
SNU475 DNM1
Mean 14.2
Standard deviation 4.2
Values 11 17
[314]
THLE DNM1
Mean 11.2
Standard deviation 0.44
Values 11 11
[315]
liver DNM1
Mean 0.869
Standard deviation 0.9
Values 2.2 0.36 0.73 0.21
[316]
ref_hepatocyte GAD1
Mean 0.132
Standard deviation 0.29
Values 0 0 0 0 0.66
[317]
HepG2 GAD1
Mean 0.511
Standard deviation 0.23
Values 0.35 0.67
[318]
HepG2.C3A GAD1
Mean 0.567
Standard deviation 0.17
Values 0.69 0.45
[319]
HuH.7 GAD1
Mean 5.59
Standard deviation 0.85
Values 5.4 6.5 4.9
[320]
SNU475 GAD1
Mean 0.101
Standard deviation 0.044
Values 0.13 0.07
[321]
THLE GAD1
Mean 0.253
Standard deviation 0.1
Values 0.33 0.18
[322]
liver GAD1
Mean 0.0135
Standard deviation 0.019
Values 0.04 0.014 0 0
[323]
ref_hepatocyte SOD3
Mean 0.0499
Standard deviation 0.071
Values 0 0.15 0.095 0 0
[324]
HepG2 SOD3
Mean 0.0122
Standard deviation 0.001
Values 0.013 0.011
[325]
HepG2.C3A SOD3
Mean 0.0199
Standard deviation 0.013
Values 0.011 0.029
[326]
HuH.7 SOD3
Mean 0
Standard deviation 0
Values 0 0 0
[327]
SNU475 SOD3
Mean 0.45
Standard deviation 0.13
Values 0.54 0.36
[328]
THLE SOD3
Mean 0.0426
Standard deviation 0.015
Values 0.053 0.032
[329]
liver SOD3
Mean 1.49
Standard deviation 0.55
Values 1.5 0.96 2.3 1.3
[330]
ref_hepatocyte GAD2
Mean 0.0065
Standard deviation 0.015
Values 0 0.033 0 0 0
[331]
HepG2 GAD2
Missing
[332]
HepG2.C3A GAD2
Missing
[333]
HuH.7 GAD2
Missing
[334]
SNU475 GAD2
Missing
[335]
THLE GAD2
Missing
[336]
liver GAD2
Missing
[337]
ref_hepatocyte CBSL
Missing
[338]
HepG2 CBSL
Missing
[339]
HepG2.C3A CBSL
Missing
[340]
HuH.7 CBSL
Missing
[341]
SNU475 CBSL
Missing
[342]
THLE CBSL
Missing
[343]
liver CBSL
Missing
[344]
ref_hepatocyte MIR6778
Missing
[345]
HepG2 MIR6778
Missing
[346]
HepG2.C3A MIR6778
Missing
[347]
HuH.7 MIR6778
Missing
[348]
SNU475 MIR6778
Missing
[349]
THLE MIR6778
Missing
[350]
liver MIR6778
Missing
[351]
ref_hepatocyte GPX5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[352]
HepG2 GPX5
Mean 0
Standard deviation 0
Values 0 0
[353]
HepG2.C3A GPX5
Mean 0
Standard deviation 0
Values 0 0
[354]
HuH.7 GPX5
Mean 0
Standard deviation 0
Values 0 0 0
[355]
SNU475 GPX5
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[356]
THLE GPX5
Mean 0
Standard deviation 0
Values 0 0
[357]
liver GPX5
Mean 0.00642
Standard deviation 0.013
Values 0 0 0 0.026
[358]
ref_hepatocyte GPX6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[359]
HepG2 GPX6
Mean 0
Standard deviation 0
Values 0 0
[360]
HepG2.C3A GPX6
Mean 0
Standard deviation 0
Values 0 0
[361]
HuH.7 GPX6
Mean 0
Standard deviation 0
Values 0 0 0
[362]
SNU475 GPX6
Mean 0
Standard deviation 0
Values 0 0
[363]
THLE GPX6
Mean 0
Standard deviation 0
Values 0 0
[364]
liver GPX6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[365]
ref_hepatocyte SOD2-OT1
Missing
[366]
HepG2 SOD2-OT1
Missing
[367]
HepG2.C3A SOD2-OT1
Missing
[368]
HuH.7 SOD2-OT1
Missing
[369]
SNU475 SOD2-OT1
Missing
[370]
THLE SOD2-OT1
Missing
[371]
liver SOD2-OT1
Missing
[372]
ref_hepatocyte DHFR2
Missing
[373]
HepG2 DHFR2
Missing
[374]
HepG2.C3A DHFR2
Missing
[375]
HuH.7 DHFR2
Missing
[376]
SNU475 DHFR2
Missing
[377]
THLE DHFR2
Missing
[378]
liver DHFR2
Missing