WP_NUCLEOTIDE_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SAT1 Diamine acetyltransferase 1 [1] -1.01[2] -1.24[3] -1.17[4] -2.55[5] -1.36[6] 0.30[7]
2 OAZ1 Ornithine decarboxylase antizyme 1 [8] 0.02[9] 0.00[10] -0.23[11] 0.02[12] -0.03[13] 0.18[14]
3 NME2 Nucleoside diphosphate kinase B [15] -2.98[16] -3.25[17] -2.64[18] -3.26[19] -3.71[20] -4.93[21]
4 SRM Spermidine synthase [22] 0.53[23] 1.00[24] -0.25[25] 0.50[26] 0.39[27] -0.45[28]
5 ADSL Adenylosuccinate lyase [29] 1.23[30] 1.23[31] 1.82[32] 0.53[33] 0.18[34] 0.56[35]
6 PRPS1 Ribose-phosphate pyrophosphokinase 1 [36] [37] [38] [39] [40] [41] [42]
7 HPRT1 Hypoxanthine-guanine phosphoribosyltransferase [43] 0.24[44] 0.23[45] 1.42[46] 1.50[47] 1.07[48] -0.01[49]
8 RRM2 Ribonucleoside-diphosphate reductase subunit M2 [50] 2.65[51] 2.58[52] 2.28[53] 3.63[54] 3.25[55] 0.98[56]
9 POLB DNA polymerase beta [57] 0.14[58] -0.02[59] 0.24[60] -0.77[61] -1.00[62] 0.32[63]
10 RRM1 Ribonucleoside-diphosphate reductase large subunit [64] 2.54[65] 1.87[66] 2.77[67] 3.57[68] 3.26[69] 1.91[70]
11 PRPS2 Ribose-phosphate pyrophosphokinase 2 [71] [72] [73] [74] [75] [76] [77]
12 POLG DNA polymerase subunit gamma-1 [78] 1.66[79] 1.22[80] 1.73[81] 1.90[82] 1.66[83] 2.49[84]
13 DHFR Dihydrofolate reductase [85] 2.61[86] 3.12[87] 3.66[88] 2.77[89] 3.21[90] 1.94[91]
14 RRM2B Ribonucleoside-diphosphate reductase subunit M2 B [92] 2.31[93] 2.27[94] 1.30[95] 2.52[96] 1.90[97] 2.27[98]
15 MTHFD2 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial 3.97[99] 4.60[100] 3.47[101] 1.25[102] 3.57[103] -0.53[104]
16 IMPDH1 Inosine-5'-monophosphate dehydrogenase 1 [105] 2.98[106] 2.07[107] 2.02[108] 3.57[109] 2.62[110] 0.58[111]
17 POLD1 DNA polymerase delta catalytic subunit [112] 2.93[113] 2.95[114] 3.97[115] 3.34[116] 3.68[117] 2.48[118]
18 POLA1 DNA polymerase alpha catalytic subunit [119] 3.08[120] 2.99[121] 3.75[122] 4.50[123] 4.05[124] 3.49[125]
19 ADSS2 [126] [127] [128] [129] [130] [131] [132]
[1]
ref_hepatocyte SAT1
Mean 281
Standard deviation 1.6e+02
Values 5.1e+02 2.5e+02 1.9e+02 89 3.7e+02
[2]
HepG2 SAT1
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[3]
HepG2.C3A SAT1
Mean 128
Standard deviation 33
Values 1e+02 1.5e+02
[4]
HuH.7 SAT1
Mean 112
Standard deviation 22
Values 1.3e+02 1.2e+02 86
[5]
SNU475 SAT1
Mean 30.8
Standard deviation 7.6
Values 36 25
[6]
THLE SAT1
Mean 105
Standard deviation 31
Values 1.3e+02 84
[7]
liver SAT1
Mean 139
Standard deviation 1.2e+02
Values 42 48 2.9e+02 1.8e+02
[8]
ref_hepatocyte OAZ1
Mean 222
Standard deviation 1.1e+02
Values 3.4e+02 2.3e+02 3.2e+02 1e+02 1.3e+02
[9]
HepG2 OAZ1
Mean 238
Standard deviation 19
Values 2.2e+02 2.5e+02
[10]
HepG2.C3A OAZ1
Mean 240
Standard deviation 9.1
Values 2.5e+02 2.3e+02
[11]
HuH.7 OAZ1
Mean 170
Standard deviation 46
Values 2.1e+02 1.2e+02 1.8e+02
[12]
SNU475 OAZ1
Mean 144
Standard deviation 20
Values 1.3e+02 1.6e+02
[13]
THLE OAZ1
Mean 210
Standard deviation 17
Values 2e+02 2.2e+02
[14]
liver OAZ1
Mean 101
Standard deviation 69
Values 45 39 1.7e+02 1.5e+02
[15]
ref_hepatocyte NME2
Mean 210
Standard deviation 1.1e+02
Values 2.6e+02 1.5e+02 3.7e+02 97 1.8e+02
[16]
HepG2 NME2
Mean 28.1
Standard deviation 7.3
Values 23 33
[17]
HepG2.C3A NME2
Mean 23.9
Standard deviation 1.1
Values 25 23
[18]
HuH.7 NME2
Mean 30.3
Standard deviation 2
Values 29 29 33
[19]
SNU475 NME2
Mean 14.1
Standard deviation 3.8
Values 11 17
[20]
THLE NME2
Mean 15.4
Standard deviation 5.7
Values 11 19
[21]
liver NME2
Mean 2.78
Standard deviation 3.3
Values 0.053 0.086 4.3 6.7
[22]
ref_hepatocyte SRM
Mean 28.1
Standard deviation 25
Values 70 16 33 6.5 15
[23]
HepG2 SRM
Mean 42.7
Standard deviation 0.29
Values 43 43
[24]
HepG2.C3A SRM
Mean 60.7
Standard deviation 5.5
Values 65 57
[25]
HuH.7 SRM
Mean 21.2
Standard deviation 10
Values 27 9.7 27
[26]
SNU475 SRM
Mean 25.5
Standard deviation 6.7
Values 30 21
[27]
THLE SRM
Mean 35.3
Standard deviation 5.7
Values 31 39
[28]
liver SRM
Mean 8.26
Standard deviation 6.7
Values 2.5 2.4 14 14
[29]
ref_hepatocyte ADSL
Mean 25
Standard deviation 12
Values 21 12 17 34 40
[30]
HepG2 ADSL
Mean 61.7
Standard deviation 4
Values 59 65
[31]
HepG2.C3A ADSL
Mean 63.3
Standard deviation 4.7
Values 67 60
[32]
HuH.7 ADSL
Mean 79.7
Standard deviation 15
Values 94 64 81
[33]
SNU475 ADSL
Mean 23.2
Standard deviation 2.7
Values 25 21
[34]
THLE ADSL
Mean 27.3
Standard deviation 7.7
Values 22 33
[35]
liver ADSL
Mean 14.9
Standard deviation 3.2
Values 11 16 14 18
[36]
ref_hepatocyte PRPS1
Mean 18.8
Standard deviation 5.2
Values 22 17 16 13 26
[37]
HepG2 PRPS1
Missing
[38]
HepG2.C3A PRPS1
Missing
[39]
HuH.7 PRPS1
Missing
[40]
SNU475 PRPS1
Missing
[41]
THLE PRPS1
Missing
[42]
liver PRPS1
Missing
[43]
ref_hepatocyte HPRT1
Mean 13.6
Standard deviation 5.4
Values 8.9 15 7.3 17 20
[44]
HepG2 HPRT1
Mean 16.9
Standard deviation 0.27
Values 17 17
[45]
HepG2.C3A HPRT1
Mean 17.3
Standard deviation 2.3
Values 19 16
[46]
HuH.7 HPRT1
Mean 32.8
Standard deviation 5.1
Values 38 28 32
[47]
SNU475 HPRT1
Mean 24.8
Standard deviation 3.3
Values 22 27
[48]
THLE HPRT1
Mean 27.5
Standard deviation 1.6
Values 26 29
[49]
liver HPRT1
Mean 5.44
Standard deviation 5.1
Values 1.1 1.6 7.1 12
[50]
ref_hepatocyte RRM2
Mean 11.3
Standard deviation 12
Values 0.89 2.6 4.7 21 27
[51]
HepG2 RRM2
Mean 74.3
Standard deviation 40
Values 1e+02 46
[52]
HepG2.C3A RRM2
Mean 72.7
Standard deviation 62
Values 1.2e+02 29
[53]
HuH.7 RRM2
Mean 49
Standard deviation 32
Values 68 12 67
[54]
SNU475 RRM2
Mean 89.3
Standard deviation 5.3
Values 93 86
[55]
THLE RRM2
Mean 103
Standard deviation 25
Values 85 1.2e+02
[56]
liver RRM2
Mean 8.94
Standard deviation 9.7
Values 0.81 9.4 3.1 22
[57]
ref_hepatocyte POLB
Mean 10.8
Standard deviation 1.8
Values 12 11 8.8 9.3 13
[58]
HepG2 POLB
Mean 12.5
Standard deviation 2.5
Values 14 11
[59]
HepG2.C3A POLB
Mean 11.5
Standard deviation 2.8
Values 13 9.5
[60]
HuH.7 POLB
Mean 11.5
Standard deviation 2.4
Values 14 10 10
[61]
SNU475 POLB
Mean 4.06
Standard deviation 0.015
Values 4.1 4.1
[62]
THLE POLB
Mean 5.21
Standard deviation 0.74
Values 5.7 4.7
[63]
liver POLB
Mean 5.42
Standard deviation 4
Values 1.5 2.8 7.1 10
[64]
ref_hepatocyte RRM1
Mean 8.31
Standard deviation 6.1
Values 3.3 4.7 5 11 18
[65]
HepG2 RRM1
Mean 51
Standard deviation 21
Values 66 37
[66]
HepG2.C3A RRM1
Mean 32.9
Standard deviation 21
Values 47 18
[67]
HuH.7 RRM1
Mean 51
Standard deviation 15
Values 61 34 59
[68]
SNU475 RRM1
Mean 63.2
Standard deviation 3.6
Values 66 61
[69]
THLE RRM1
Mean 76.5
Standard deviation 23
Values 60 93
[70]
liver RRM1
Mean 12.6
Standard deviation 3.4
Values 10 15 9.3 16
[71]
ref_hepatocyte PRPS2
Mean 7.85
Standard deviation 4.2
Values 2.7 10 5.9 6.8 14
[72]
HepG2 PRPS2
Missing
[73]
HepG2.C3A PRPS2
Missing
[74]
HuH.7 PRPS2
Missing
[75]
SNU475 PRPS2
Missing
[76]
THLE PRPS2
Missing
[77]
liver PRPS2
Missing
[78]
ref_hepatocyte POLG
Mean 7.58
Standard deviation 4.2
Values 11 2.9 6.8 4.5 12
[79]
HepG2 POLG
Mean 25.2
Standard deviation 1.8
Values 27 24
[80]
HepG2.C3A POLG
Mean 19
Standard deviation 3.1
Values 17 21
[81]
HuH.7 POLG
Mean 22.6
Standard deviation 4.8
Values 24 17 27
[82]
SNU475 POLG
Mean 18.2
Standard deviation 2.7
Values 20 16
[83]
THLE POLG
Mean 23.1
Standard deviation 0.32
Values 23 23
[84]
liver POLG
Mean 17.2
Standard deviation 8.9
Values 28 22 10 9.3
[85]
ref_hepatocyte DHFR
Mean 6.89
Standard deviation 3.8
Values 0.65 9.3 6.3 10 7.9
[86]
HepG2 DHFR
Mean 44.3
Standard deviation 17
Values 56 32
[87]
HepG2.C3A DHFR
Mean 64.7
Standard deviation 42
Values 95 35
[88]
HuH.7 DHFR
Mean 78.4
Standard deviation 42
Values 96 31 1.1e+02
[89]
SNU475 DHFR
Mean 30.2
Standard deviation 0.92
Values 30 31
[90]
THLE DHFR
Mean 61.5
Standard deviation 17
Values 50 73
[91]
liver DHFR
Mean 10.7
Standard deviation 3.8
Values 12 9.2 15 6.4
[92]
ref_hepatocyte RRM2B
Mean 5.12
Standard deviation 4.1
Values 2.8 2.6 1.6 7.3 11
[93]
HepG2 RRM2B
Mean 26.7
Standard deviation 1.8
Values 28 25
[94]
HepG2.C3A RRM2B
Mean 26.7
Standard deviation 5.2
Values 30 23
[95]
HuH.7 RRM2B
Mean 11.3
Standard deviation 1.7
Values 9.5 13 12
[96]
SNU475 RRM2B
Mean 18.9
Standard deviation 5.1
Values 15 23
[97]
THLE RRM2B
Mean 18.4
Standard deviation 0.84
Values 19 18
[98]
liver RRM2B
Mean 9.96
Standard deviation 2.3
Values 8.6 12 7.4 12
[99]
ref_hepatocyte MTHFD2
Mean 4.93
Standard deviation 5.2
Values 5.2 1.3 3.3 14 1.1
[100]
HepG2 MTHFD2
Mean 81.4
Standard deviation 25
Values 64 99
[101]
HepG2.C3A MTHFD2
Mean 129
Standard deviation 63
Values 84 1.7e+02
[102]
HuH.7 MTHFD2
Mean 49.2
Standard deviation 11
Values 55 37 55
[103]
SNU475 MTHFD2
Mean 7.54
Standard deviation 0.064
Values 7.5 7.6
[104]
THLE MTHFD2
Mean 56.2
Standard deviation 0.51
Values 56 57
[105]
liver MTHFD2
Mean 1.38
Standard deviation 0.47
Values 1.2 1.2 2.1 1
[106]
ref_hepatocyte IMPDH1
Mean 4.53
Standard deviation 3.3
Values 5.1 1.2 1.2 8.6 6.6
[107]
HepG2 IMPDH1
Mean 37.5
Standard deviation 10
Values 30 45
[108]
HepG2.C3A IMPDH1
Mean 20.5
Standard deviation 4.3
Values 17 24
[109]
HuH.7 IMPDH1
Mean 16.5
Standard deviation 2.6
Values 17 14 19
[110]
SNU475 IMPDH1
Mean 34.6
Standard deviation 1.1
Values 35 34
[111]
THLE IMPDH1
Mean 26.8
Standard deviation 3.7
Values 24 29
[112]
liver IMPDH1
Mean 2.72
Standard deviation 0.62
Values 3.4 2.2 2.2 3.1
[113]
ref_hepatocyte POLD1
Mean 2.41
Standard deviation 0.8
Values 2.7 1.4 2.4 2 3.5
[114]
HepG2 POLD1
Mean 19.3
Standard deviation 1.9
Values 18 21
[115]
HepG2.C3A POLD1
Mean 20.1
Standard deviation 2.3
Values 22 18
[116]
HuH.7 POLD1
Mean 34
Standard deviation 15
Values 44 16 42
[117]
SNU475 POLD1
Mean 15.6
Standard deviation 2.9
Values 18 14
[118]
THLE POLD1
Mean 29.7
Standard deviation 2.6
Values 28 32
[119]
liver POLD1
Mean 5.43
Standard deviation 0.68
Values 5.1 4.7 6.2 5.8
[120]
ref_hepatocyte POLA1
Mean 0.985
Standard deviation 0.81
Values 0.27 0.41 0.52 1.8 2
[121]
HepG2 POLA1
Mean 8.75
Standard deviation 4.7
Values 12 5.4
[122]
HepG2.C3A POLA1
Mean 8.42
Standard deviation 3.5
Values 11 5.9
[123]
HuH.7 POLA1
Mean 11.9
Standard deviation 5.3
Values 13 6.3 17
[124]
SNU475 POLA1
Mean 14.3
Standard deviation 5.6
Values 18 10
[125]
THLE POLA1
Mean 15.7
Standard deviation 1.1
Values 15 17
[126]
liver POLA1
Mean 4.45
Standard deviation 2.4
Values 4.8 7.6 1.9 3.5
[127]
ref_hepatocyte ADSS2
Missing
[128]
HepG2 ADSS2
Missing
[129]
HepG2.C3A ADSS2
Missing
[130]
HuH.7 ADSS2
Missing
[131]
SNU475 ADSS2
Missing
[132]
THLE ADSS2
Missing
[133]
liver ADSS2
Missing