WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2E1 Cytochrome P450 2E1 [1] -11.37[2] -11.83[3] -8.08[4] -12.20[5] -10.13[6] -0.98[7]
2 CYP2C9 Cytochrome P450 2C9 [8] [9] -13.87[10] -6.45[11] -11.97[12] -10.66[13] 0.45[14]
3 CYP3A4 Cytochrome P450 3A4 [15] -8.62[16] -9.06[17] -10.26[18] -12.28[19] -10.24[20] 0.16[21]
4 CYP4A11 Cytochrome P450 4A11 [22] -11.54[23] -9.23[24] -10.59[25] -8.10[26] -8.61[27] 0.31[28]
5 CYP1A2 Cytochrome P450 1A2 [29] -7.79[30] -6.82[31] -6.96[32] -5.85[33] -5.77[34] -2.22[35]
6 CYP2B6 Cytochrome P450 2B6 [36] -6.51[37] -3.40[38] -1.52[39] -6.84[40] -7.34[41] 1.83[42]
7 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [43] -5.09[44] -2.87[45] -6.28[46] -5.75[47] -7.07[48] 1.88[49]
8 ABCC2 Canalicular multispecific organic anion transporter 1 [50] 3.96[51] 5.21[52] 4.14[53] 3.98[54] -2.29[55] 1.38[56]
9 NR1I3 Nuclear receptor subfamily 1 group I member 3 [57] -4.95[58] -3.76[59] -3.15[60] -5.51[61] -4.29[62] -1.13[63]
10 NR1H4 Bile acid receptor [64] 1.53[65] 1.80[66] 4.10[67] -3.82[68] -3.34[69] -0.05[70]
11 ABCD3 ATP-binding cassette sub-family D member 3 [71] 2.97[72] 3.50[73] 4.06[74] 4.05[75] 4.47[76] 1.14[77]
12 NR1H3 Oxysterols receptor LXR-alpha [78] 1.46[79] 2.16[80] 3.60[81] 1.50[82] 0.66[83] -0.88[84]
13 ABCC3 Canalicular multispecific organic anion transporter 2 [85] 4.21[86] 3.21[87] 2.09[88] 4.50[89] 4.41[90] 2.07[91]
14 ABCB1 Multidrug resistance protein 1 [92] 2.54[93] 3.74[94] 2.63[95] -1.62[96] -2.78[97] 0.11[98]
15 PPARD Peroxisome proliferator-activated receptor delta [99] 2.76[100] 1.90[101] 2.14[102] 4.31[103] 5.23[104] -2.20[105]
16 NR1I2 Nuclear receptor subfamily 1 group I member 2 [106] 1.74[107] 1.17[108] -2.85[109] -5.79[110] -4.33[111] 1.12[112]
17 ABCB4 Phosphatidylcholine translocator ABCB4 [113] 1.27[114] 1.79[115] 3.08[116] -1.13[117] -4.44[118] 3.01[119]
18 ABCG5 ATP-binding cassette sub-family G member 5 [120] 1.14[121] 2.98[122] -3.61[123] -8.04[124] -5.51[125] 1.26[126]
19 RARA Retinoic acid receptor alpha [127] 3.73[128] 1.99[129] 3.04[130] 5.40[131] 5.36[132] -0.42[133]
20 ABCA1 ATP-binding cassette sub-family A member 1 [134] 4.79[135] 5.38[136] 5.67[137] 5.45[138] 6.52[139] 4.64[140]
21 CYP7A1 Cholesterol 7-alpha-monooxygenase [141] -1.22[142] -3.87[143] -6.89[144] -5.74[145] [146] -3.53[147]
22 PPARA Peroxisome proliferator-activated receptor alpha [148] 3.80[149] 4.46[150] 5.82[151] 4.27[152] 3.94[153] 3.58[154]
23 PPARG Peroxisome proliferator-activated receptor gamma [155] 3.04[156] 4.34[157] 5.36[158] 5.08[159] 5.55[160] -0.95[161]
24 ABCB11 Bile salt export pump [162] -3.67[163] [164] -2.17[165] -1.29[166] [167] 4.22[168]
25 ABCG1 ATP-binding cassette sub-family G member 1 [169] 2.11[170] -4.15[171] 2.04[172] -1.25[173] 4.34[174] 1.35[175]
26 CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [176] 11.27[177] 6.09[178] 0.95[179] 8.34[180] 2.04[181] -7.67[182]
27 VDR Vitamin D3 receptor [183] 2.96[184] 3.07[185] 4.22[186] 6.57[187] 8.41[188] -0.09[189]
28 CYP26A1 Cytochrome P450 26A1 [190] 6.29[191] 0.14[192] 4.19[193] 4.38[194] -0.80[195] 0.43[196]
29 RARG Retinoic acid receptor gamma [197] 7.11[198] 4.69[199] 6.91[200] 10.53[201] 10.86[202] 2.46[203]
30 RARB Retinoic acid receptor beta [204] 4.56[205] 1.03[206] 7.37[207] 10.06[208] 9.13[209] 4.20[210]
31 CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [211] 5.80[212] 6.92[213] 6.82[214] 5.42[215] 6.66[216] 1.10[217]
32 ABCD2 ATP-binding cassette sub-family D member 2 [218] [219] [220] 3.25[221] 8.19[222] 9.33[223] 2.71[224]
33 MIR33B [225] [226] [227] [228] [229] [230] [231]
34 CYP4B1 Cytochrome P450 4B1 [232] [233] [234] [235] [236] [237] [238]
35 MIR33A [239] [240] [241] [242] [243] [244] [245]
[1]
ref_hepatocyte CYP2E1
Mean 1.39e+03
Standard deviation 1.9e+03
Values 90 4.1e+03 2.7e+03 0 4.6
[2]
HepG2 CYP2E1
Mean 0.133
Standard deviation 0.1
Values 0.06 0.21
[3]
HepG2.C3A CYP2E1
Mean 0.107
Standard deviation 0.15
Values 0 0.21
[4]
HuH.7 CYP2E1
Mean 0.975
Standard deviation 0.29
Values 0.99 1.3 0.67
[5]
SNU475 CYP2E1
Mean 0.0289
Standard deviation 0.005
Values 0.025 0.032
[6]
THLE CYP2E1
Mean 0.0955
Standard deviation 0.082
Values 0.15 0.037
[7]
liver CYP2E1
Mean 1.49e+03
Standard deviation 8.2e+02
Values 6.9e+02 1e+03 2.6e+03 1.7e+03
[8]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 21 9.2e+02 4.7e+02 0.064 20
[9]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[10]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0.011 0
[11]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[12]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0 0.014
[13]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[14]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 2.9e+02 6.1e+02 8.6e+02 1.5e+03
[15]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 11 9.6e+02 3.2e+02 0.24 11
[16]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.24 0.097
[17]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.2 0.068
[18]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.047 0.064 0.0082
[19]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0.01 0
[20]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[21]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 49 6.4e+02 4.3e+02 1.3e+03
[22]
ref_hepatocyte CYP4A11
Mean 109
Standard deviation 1.6e+02
Values 4 3.4e+02 2e+02 0 0
[23]
HepG2 CYP4A11
Mean 0.0093
Standard deviation 0.005
Values 0.013 0.0057
[24]
HepG2.C3A CYP4A11
Mean 0.0511
Standard deviation 0.0036
Values 0.054 0.049
[25]
HuH.7 CYP4A11
Mean 0.0135
Standard deviation 0.0098
Values 0.0094 0.0064 0.025
[26]
SNU475 CYP4A11
Mean 0.039
Standard deviation 0.0093
Values 0.046 0.032
[27]
THLE CYP4A11
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[28]
liver CYP4A11
Mean 286
Standard deviation 2.2e+02
Values 1.3e+02 87 5.7e+02 3.6e+02
[29]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.97 3e+02 71 0.4 18
[30]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.13 0.052
[31]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.15 0.24
[32]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.15 0.1 0.11
[33]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.2 0.07
[34]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[35]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 19 12 55 58
[36]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 12 1e+02 1.3e+02 0 4.1
[37]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.034 0.24
[38]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 0.92 1.7
[39]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 1.9 5.9 2.1
[40]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.071 0.014
[41]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[42]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 7.4 3.2e+02 23 1.1e+03
[43]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 6.4 86 79 1.2 0.33
[44]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.4 0.11
[45]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 0.98 1.7
[46]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.066 0.096 0.09
[47]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.066 0.06
[48]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[49]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 2.2e+02 1.3e+02 4.2e+02 3e+02
[50]
ref_hepatocyte ABCC2
Mean 31.6
Standard deviation 23
Values 16 17 17 68 40
[51]
HepG2 ABCC2
Mean 125
Standard deviation 1.3
Values 1.3e+02 1.2e+02
[52]
HepG2.C3A ABCC2
Mean 328
Standard deviation 1.2
Values 3.3e+02 3.3e+02
[53]
HuH.7 ABCC2
Mean 105
Standard deviation 48
Values 68 1.6e+02 88
[54]
SNU475 ABCC2
Mean 48.9
Standard deviation 12
Values 41 57
[55]
THLE ABCC2
Mean 0.497
Standard deviation 0.041
Values 0.53 0.47
[56]
liver ABCC2
Mean 174
Standard deviation 96
Values 1.9e+02 3e+02 89 1.1e+02
[57]
ref_hepatocyte NR1I3
Mean 21.5
Standard deviation 28
Values 3.1 56 46 0.98 0.67
[58]
HepG2 NR1I3
Mean 0.177
Standard deviation 0.0012
Values 0.18 0.18
[59]
HepG2.C3A NR1I3
Mean 0.446
Standard deviation 0.084
Values 0.39 0.51
[60]
HuH.7 NR1I3
Mean 0.459
Standard deviation 0.23
Values 0.34 0.72 0.32
[61]
SNU475 NR1I3
Mean 0.0462
Standard deviation 0.0063
Values 0.051 0.042
[62]
THLE NR1I3
Mean 0.0849
Standard deviation 0.022
Values 0.1 0.069
[63]
liver NR1I3
Mean 20.7
Standard deviation 18
Values 7.7 6.7 46 23
[64]
ref_hepatocyte NR1H4
Mean 20.8
Standard deviation 17
Values 3.8 33 43 15 9.3
[65]
HepG2 NR1H4
Mean 15.2
Standard deviation 6.4
Values 20 11
[66]
HepG2.C3A NR1H4
Mean 20.3
Standard deviation 1.1
Values 21 19
[67]
HuH.7 NR1H4
Mean 67.4
Standard deviation 13
Values 58 82 62
[68]
SNU475 NR1H4
Mean 0.144
Standard deviation 0.04
Values 0.17 0.12
[69]
THLE NR1H4
Mean 0.158
Standard deviation 0.028
Values 0.18 0.14
[70]
liver NR1H4
Mean 42.4
Standard deviation 11
Values 39 37 59 35
[71]
ref_hepatocyte ABCD3
Mean 18.8
Standard deviation 10
Values 5.3 32 17 26 14
[72]
HepG2 ABCD3
Mean 37.1
Standard deviation 21
Values 52 22
[73]
HepG2.C3A ABCD3
Mean 59.7
Standard deviation 22
Values 75 44
[74]
HuH.7 ABCD3
Mean 59.3
Standard deviation 4.4
Values 57 56 64
[75]
SNU475 ABCD3
Mean 30.3
Standard deviation 5.6
Values 26 34
[76]
THLE ABCD3
Mean 32.1
Standard deviation 2.2
Values 31 34
[77]
liver ABCD3
Mean 87.4
Standard deviation 1.3
Values 89 87 86 88
[78]
ref_hepatocyte NR1H3
Mean 14.8
Standard deviation 10
Values 6.4 29 22 6.4 9.6
[79]
HepG2 NR1H3
Mean 10.3
Standard deviation 0.1
Values 10 10
[80]
HepG2.C3A NR1H3
Mean 18.6
Standard deviation 4.7
Values 15 22
[81]
HuH.7 NR1H3
Mean 33.8
Standard deviation 2.7
Values 35 36 31
[82]
SNU475 NR1H3
Mean 4.08
Standard deviation 1.1
Values 4.8 3.3
[83]
THLE NR1H3
Mean 1.8
Standard deviation 0.21
Values 1.7 1.9
[84]
liver NR1H3
Mean 16.9
Standard deviation 7.5
Values 9.7 12 25 21
[85]
ref_hepatocyte ABCC3
Mean 14.4
Standard deviation 9.9
Values 5 9.7 31 14 12
[86]
HepG2 ABCC3
Mean 67.6
Standard deviation 20
Values 54 81
[87]
HepG2.C3A ABCC3
Mean 37.4
Standard deviation 7.2
Values 32 42
[88]
HuH.7 ABCC3
Mean 11.6
Standard deviation 4.6
Values 10 17 7.9
[89]
SNU475 ABCC3
Mean 31.8
Standard deviation 16
Values 21 43
[90]
THLE ABCC3
Mean 23.7
Standard deviation 5.8
Values 28 20
[91]
liver ABCC3
Mean 128
Standard deviation 23
Values 1.3e+02 1.4e+02 93 1.5e+02
[92]
ref_hepatocyte ABCB1
Mean 12.8
Standard deviation 7
Values 15 5.6 5.4 17 21
[93]
HepG2 ABCB1
Mean 18.8
Standard deviation 3.2
Values 21 17
[94]
HepG2.C3A ABCB1
Mean 47.9
Standard deviation 1.3
Values 49 47
[95]
HuH.7 ABCB1
Mean 15
Standard deviation 8.7
Values 9 25 11
[96]
SNU475 ABCB1
Mean 0.405
Standard deviation 0.094
Values 0.47 0.34
[97]
THLE ABCB1
Mean 0.143
Standard deviation 0.0068
Values 0.15 0.14
[98]
liver ABCB1
Mean 29
Standard deviation 14
Values 31 46 13 26
[99]
ref_hepatocyte PPARD
Mean 10.1
Standard deviation 15
Values 37 2.2 7.9 1.4 2.3
[100]
HepG2 PPARD
Mean 17.4
Standard deviation 8.1
Values 12 23
[101]
HepG2.C3A PPARD
Mean 10.6
Standard deviation 2.3
Values 8.9 12
[102]
HuH.7 PPARD
Mean 8.45
Standard deviation 0.13
Values 8.3 8.5 8.5
[103]
SNU475 PPARD
Mean 19.7
Standard deviation 2.2
Values 18 21
[104]
THLE PPARD
Mean 29.3
Standard deviation 0.077
Values 29 29
[105]
liver PPARD
Mean 4.66
Standard deviation 1.3
Values 5.3 2.7 4.8 5.8
[106]
ref_hepatocyte NR1I2
Mean 9.56
Standard deviation 6.3
Values 6.4 18 15 5.2 3.7
[107]
HepG2 NR1I2
Mean 8.09
Standard deviation 2.1
Values 9.6 6.6
[108]
HepG2.C3A NR1I2
Mean 6.05
Standard deviation 2.4
Values 7.8 4.3
[109]
HuH.7 NR1I2
Mean 0.251
Standard deviation 0.064
Values 0.23 0.32 0.2
[110]
SNU475 NR1I2
Mean 0.0169
Standard deviation 0.0024
Values 0.015 0.019
[111]
THLE NR1I2
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[112]
liver NR1I2
Mean 43.7
Standard deviation 13
Values 38 37 63 37
[113]
ref_hepatocyte ABCB4
Mean 8.09
Standard deviation 7.8
Values 1.4 12 20 3 4
[114]
HepG2 ABCB4
Mean 4.92
Standard deviation 0.38
Values 5.2 4.7
[115]
HepG2.C3A ABCB4
Mean 7.87
Standard deviation 1.3
Values 6.9 8.8
[116]
HuH.7 ABCB4
Mean 12.9
Standard deviation 0.78
Values 12 14 13
[117]
SNU475 ABCB4
Mean 0.362
Standard deviation 0.12
Values 0.27 0.45
[118]
THLE ABCB4
Mean 0.0287
Standard deviation 0.018
Values 0.041 0.016
[119]
liver ABCB4
Mean 138
Standard deviation 90
Values 2.6e+02 1.5e+02 55 89
[120]
ref_hepatocyte ABCG5
Mean 6.81
Standard deviation 7.7
Values 0.43 18 12 3.9 0.22
[121]
HepG2 ABCG5
Mean 3.81
Standard deviation 0.63
Values 4.3 3.4
[122]
HepG2.C3A ABCG5
Mean 15.1
Standard deviation 4
Values 12 18
[123]
HuH.7 ABCG5
Mean 0.105
Standard deviation 0.098
Values 0.056 0.22 0.041
[124]
SNU475 ABCG5
Mean 0.00253
Standard deviation 0.0036
Values 0.0051 0
[125]
THLE ABCG5
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[126]
liver ABCG5
Mean 34.4
Standard deviation 19
Values 24 18 61 34
[127]
ref_hepatocyte RARA
Mean 5.02
Standard deviation 3.8
Values 5.4 7.5 9.8 1.1 1.3
[128]
HepG2 RARA
Mean 16.9
Standard deviation 3.5
Values 14 19
[129]
HepG2.C3A RARA
Mean 5.59
Standard deviation 2.4
Values 3.9 7.3
[130]
HuH.7 RARA
Mean 7.81
Standard deviation 0.69
Values 7 8.3 8.1
[131]
SNU475 RARA
Mean 20.7
Standard deviation 2.1
Values 19 22
[132]
THLE RARA
Mean 15.9
Standard deviation 0.29
Values 16 16
[133]
liver RARA
Mean 7.93
Standard deviation 1
Values 7.3 7.1 8 9.3
[134]
ref_hepatocyte ABCA1
Mean 4.97
Standard deviation 4
Values 0.95 10 5.2 7.4 1.1
[135]
HepG2 ABCA1
Mean 34.8
Standard deviation 18
Values 48 22
[136]
HepG2.C3A ABCA1
Mean 58.2
Standard deviation 2.3
Values 60 57
[137]
HuH.7 ABCA1
Mean 47.7
Standard deviation 23
Values 26 73 44
[138]
SNU475 ABCA1
Mean 21.2
Standard deviation 3.5
Values 24 19
[139]
THLE ABCA1
Mean 35.1
Standard deviation 5.6
Values 39 31
[140]
liver ABCA1
Mean 262
Standard deviation 1.4e+02
Values 4.4e+02 2.8e+02 2.1e+02 1.2e+02
[141]
ref_hepatocyte CYP7A1
Mean 4.03
Standard deviation 5.2
Values 0 9.7 0.69 9.8 0
[142]
HepG2 CYP7A1
Mean 0.438
Standard deviation 0.47
Values 0.77 0.11
[143]
HepG2.C3A CYP7A1
Mean 0.0774
Standard deviation 0.027
Values 0.097 0.058
[144]
HuH.7 CYP7A1
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[145]
SNU475 CYP7A1
Mean 0.00739
Standard deviation 0.0039
Values 0.01 0.0046
[146]
THLE CYP7A1
Mean 0
Standard deviation 0
Values 0 0
[147]
liver CYP7A1
Mean 0.737
Standard deviation 0.45
Values 0.079 0.94 1.1 0.82
[148]
ref_hepatocyte PPARA
Mean 3.95
Standard deviation 2.1
Values 1.6 6.2 5.5 4.6 1.9
[149]
HepG2 PPARA
Mean 13.9
Standard deviation 0.43
Values 14 14
[150]
HepG2.C3A PPARA
Mean 24.4
Standard deviation 5.6
Values 20 28
[151]
HuH.7 PPARA
Mean 42.3
Standard deviation 18
Values 25 60 42
[152]
SNU475 PPARA
Mean 7.44
Standard deviation 1.6
Values 6.3 8.5
[153]
THLE PPARA
Mean 4.68
Standard deviation 0.38
Values 4.9 4.4
[154]
liver PPARA
Mean 99.6
Standard deviation 24
Values 79 1.3e+02 88 97
[155]
ref_hepatocyte PPARG
Mean 3.66
Standard deviation 0.37
Values 3.1 3.9 3.6 3.6 4.1
[156]
HepG2 PPARG
Mean 7.61
Standard deviation 0.54
Values 7.2 8
[157]
HepG2.C3A PPARG
Mean 20.7
Standard deviation 6.8
Values 16 26
[158]
HuH.7 PPARG
Mean 28.4
Standard deviation 6.2
Values 26 35 24
[159]
SNU475 PPARG
Mean 12.1
Standard deviation 2.4
Values 14 10
[160]
THLE PPARG
Mean 13.2
Standard deviation 1.2
Values 12 14
[161]
liver PPARG
Mean 4
Standard deviation 1.3
Values 2.5 4 3.8 5.7
[162]
ref_hepatocyte ABCB11
Mean 1.97
Standard deviation 1.6
Values 1.8 4.1 3 0 1
[163]
HepG2 ABCB11
Mean 0.0394
Standard deviation 0.025
Values 0.021 0.057
[164]
HepG2.C3A ABCB11
Mean 0
Standard deviation 0
Values 0 0
[165]
HuH.7 ABCB11
Mean 0.0829
Standard deviation 0.04
Values 0.037 0.096 0.11
[166]
SNU475 ABCB11
Mean 0.0787
Standard deviation 0.039
Values 0.11 0.051
[167]
THLE ABCB11
Mean 0
Standard deviation 0
Values 0 0
[168]
liver ABCB11
Mean 77.6
Standard deviation 77
Values 71 1.9e+02 17 36
[169]
ref_hepatocyte ABCG1
Mean 0.617
Standard deviation 0.67
Values 0.5 1.1 1.5 0 0
[170]
HepG2 ABCG1
Mean 0.677
Standard deviation 0.72
Values 0.17 1.2
[171]
HepG2.C3A ABCG1
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[172]
HuH.7 ABCG1
Mean 0.48
Standard deviation 0.39
Values 0.26 0.93 0.25
[173]
SNU475 ABCG1
Mean 0.0253
Standard deviation 0.036
Values 0.051 0
[174]
THLE ABCG1
Mean 0.966
Standard deviation 0.3
Values 1.2 0.76
[175]
liver ABCG1
Mean 3.31
Standard deviation 1.2
Values 3.9 4.6 1.9 2.8
[176]
ref_hepatocyte CYP24A1
Mean 0.344
Standard deviation 0.69
Values 0 0 0 1.6 0.15
[177]
HepG2 CYP24A1
Mean 215
Standard deviation 90
Values 1.5e+02 2.8e+02
[178]
HepG2.C3A CYP24A1
Mean 6.56
Standard deviation 2.9
Values 8.6 4.5
[179]
HuH.7 CYP24A1
Mean 0.126
Standard deviation 0.11
Values 0.019 0.24 0.11
[180]
SNU475 CYP24A1
Mean 10.9
Standard deviation 10
Values 18 3.8
[181]
THLE CYP24A1
Mean 0.109
Standard deviation 0.079
Values 0.053 0.16
[182]
liver CYP24A1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[183]
ref_hepatocyte VDR
Mean 0.333
Standard deviation 0.23
Values 0.19 0.39 0.41 0.038 0.63
[184]
HepG2 VDR
Mean 0.657
Standard deviation 0.019
Values 0.64 0.67
[185]
HepG2.C3A VDR
Mean 0.783
Standard deviation 0.23
Values 0.94 0.62
[186]
HuH.7 VDR
Mean 1.17
Standard deviation 0.57
Values 1.3 0.56 1.7
[187]
SNU475 VDR
Mean 3.08
Standard deviation 3
Values 5.2 0.97
[188]
THLE VDR
Mean 8.71
Standard deviation 1.4
Values 7.8 9.7
[189]
liver VDR
Mean 0.658
Standard deviation 0.17
Values 0.54 0.56 0.63 0.9
[190]
ref_hepatocyte CYP26A1
Mean 0.247
Standard deviation 0.38
Values 0 0.37 0.86 0 0
[191]
HepG2 CYP26A1
Mean 4.9
Standard deviation 3.4
Values 2.5 7.3
[192]
HepG2.C3A CYP26A1
Mean 0.0764
Standard deviation 0.0019
Values 0.075 0.078
[193]
HuH.7 CYP26A1
Mean 0.853
Standard deviation 0.36
Values 0.76 1.3 0.55
[194]
SNU475 CYP26A1
Mean 0.504
Standard deviation 0.37
Values 0.24 0.77
[195]
THLE CYP26A1
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[196]
liver CYP26A1
Mean 0.705
Standard deviation 0.82
Values 0.04 0.74 0.19 1.8
[197]
ref_hepatocyte RARG
Mean 0.0964
Standard deviation 0.071
Values 0.12 0.15 0.16 0.047 0
[198]
HepG2 RARG
Mean 3.38
Standard deviation 0.78
Values 2.8 3.9
[199]
HepG2.C3A RARG
Mean 0.7
Standard deviation 0.096
Values 0.63 0.77
[200]
HuH.7 RARG
Mean 2.19
Standard deviation 0.45
Values 2.6 1.7 2.2
[201]
SNU475 RARG
Mean 13.9
Standard deviation 2
Values 13 15
[202]
THLE RARG
Mean 13.8
Standard deviation 1.3
Values 13 15
[203]
liver RARG
Mean 1.12
Standard deviation 0.52
Values 0.73 0.86 1.9 1
[204]
ref_hepatocyte RARB
Mean 0.0788
Standard deviation 0.11
Values 0 0.19 0.21 0 0
[205]
HepG2 RARB
Mean 0.47
Standard deviation 0.35
Values 0.22 0.72
[206]
HepG2.C3A RARB
Mean 0.0452
Standard deviation 0.018
Values 0.032 0.058
[207]
HuH.7 RARB
Mean 2.47
Standard deviation 0.91
Values 1.7 3.5 2.2
[208]
SNU475 RARB
Mean 8.2
Standard deviation 0.6
Values 7.8 8.6
[209]
THLE RARB
Mean 3.4
Standard deviation 1.1
Values 4.2 2.6
[210]
liver RARB
Mean 3.06
Standard deviation 0.43
Values 2.8 3.6 2.7 3.2
[211]
ref_hepatocyte CYP27B1
Mean 0.0505
Standard deviation 0.082
Values 0.19 0.065 0 0 0
[212]
HepG2 CYP27B1
Mean 0.715
Standard deviation 0.14
Values 0.81 0.62
[213]
HepG2.C3A CYP27B1
Mean 1.72
Standard deviation 0.25
Values 1.5 1.9
[214]
HuH.7 CYP27B1
Mean 1.08
Standard deviation 0.18
Values 1.3 0.89 1.1
[215]
SNU475 CYP27B1
Mean 0.211
Standard deviation 0.1
Values 0.28 0.14
[216]
THLE CYP27B1
Mean 0.395
Standard deviation 0.14
Values 0.5 0.29
[217]
liver CYP27B1
Mean 0.228
Standard deviation 0.17
Values 0.24 0.14 0.071 0.46
[218]
ref_hepatocyte ABCD2
Mean 0.0114
Standard deviation 0.025
Values 0 0.057 0 0 0
[219]
HepG2 ABCD2
Mean 0
Standard deviation 0
Values 0 0
[220]
HepG2.C3A ABCD2
Mean 0
Standard deviation 0
Values 0 0
[221]
HuH.7 ABCD2
Mean 0.0204
Standard deviation 0.023
Values 0 0.045 0.016
[222]
SNU475 ABCD2
Mean 0.325
Standard deviation 0.027
Values 0.34 0.31
[223]
THLE ABCD2
Mean 0.565
Standard deviation 0.062
Values 0.61 0.52
[224]
liver ABCD2
Mean 0.158
Standard deviation 0.14
Values 0.33 0.17 0 0.13
[225]
ref_hepatocyte MIR33B
Missing
[226]
HepG2 MIR33B
Mean 0
Standard deviation 0
Values 0 0
[227]
HepG2.C3A MIR33B
Mean 0.00972
Standard deviation 0.014
Values 0 0.019
[228]
HuH.7 MIR33B
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[229]
SNU475 MIR33B
Mean 0.00232
Standard deviation 0.0033
Values 0 0.0046
[230]
THLE MIR33B
Mean 0
Standard deviation 0
Values 0 0
[231]
liver MIR33B
Mean 0
Standard deviation 0
Values 0 0 0 0
[232]
ref_hepatocyte CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[233]
HepG2 CYP4B1
Mean 0.00501
Standard deviation 0.001
Values 0.0043 0.0057
[234]
HepG2.C3A CYP4B1
Mean 0
Standard deviation 0
Values 0 0
[235]
HuH.7 CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0
[236]
SNU475 CYP4B1
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[237]
THLE CYP4B1
Mean 0.129
Standard deviation 0.077
Values 0.18 0.074
[238]
liver CYP4B1
Mean 0.0575
Standard deviation 0.045
Values 0.11 0 0.047 0.077
[239]
ref_hepatocyte MIR33A
Missing
[240]
HepG2 MIR33A
Mean 0
Standard deviation 0
Values 0 0
[241]
HepG2.C3A MIR33A
Mean 0.00486
Standard deviation 0.0069
Values 0 0.0097
[242]
HuH.7 MIR33A
Mean 0
Standard deviation 0
Values 0 0 0
[243]
SNU475 MIR33A
Mean 0
Standard deviation 0
Values 0 0
[244]
THLE MIR33A
Mean 0
Standard deviation 0
Values 0 0
[245]
liver MIR33A
Mean 0
Standard deviation 0
Values 0 0 0 0